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Cited by 476

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia

Open access
Alagaili, Abdulaziz N., Briese, Thomas, Mishra, Nischay, Kapoor, Vishal, Sameroff, Stephen C., de Wit, Emmie, Munster, Vincent J., Hensley, Lisa E., Zalmout, Iyad S., Kapoor, Amit, Epstein, Jonathan H., Karesh, William B., Daszak, Peter, Mohammed, Osama B., Lipkin, W. Ian·2014·mBio

Abstract

The Middle East respiratory syndrome (MERS) is proposed to be a zoonotic disease; however, the reservoir and mechanism for transmission of the causative agent, the MERS coronavirus, are unknown. Dromedary camels have been implicated through reports that some victims have been exposed to camels, camels in areas where the disease has emerged have antibodies to the virus, and viral sequences have been recovered from camels in association with outbreaks of the disease among humans. Nonetheless, whether camels mediate transmission to humans is unresolved. Here we provide evidence from a geographic and temporal survey of camels in the Kingdom of Saudi Arabia that MERS coronaviruses have been circulating in camels since at least 1992, are distributed countrywide, and can be phylogenetically classified into clades that correlate with outbreaks of the disease among humans. We found no evidence of infection in domestic sheep or domestic goats. IMPORTANCE This study was undertaken to determine the historical and current prevalence of Middle East respiratory syndrome (MERS) coronavirus infection in dromedary camels and other livestock in the Kingdom of Saudi Arabia, where the index case and the majority of cases of MERS have been reported.

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Research works printed but not linked: 18

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Metadata

Authors
Alagaili, A. N., Briese, T., Mishra, N., Kapoor, V., Sameroff, S. C., de Wit, E., Munster, V. J., Hensley, L. E., Zalmout, I. S., Kapoor, A., Epstein, J. H., Karesh, W. B., Daszak, P., Mohammed, O. B., & Lipkin, W. I.
Venue
mBio
Published
2014-05
Volume
5
Issue
2
Pages
e00884-14
ISSN
  • 2150-7511 (ISSN-L)
  • 2161-2129
OpenAlex
W2119837294
Cited by
476
References
1
FWCI
38.72
Type
journal article
Language
en
Open access
gold
Licence

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