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Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology

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Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle

Fisher, A. G., Seaborne, R. A., Hughes, T. M., Gutteridge, A., Stewart, C., Coulson, J., Sharples, A., & Jarvis, J. (2017) · The FASEB Journal · doi:10.1096/fj.201700089rr · Cited by 54

Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy

Bongers, K. S., Fox, D. K., Kunkel, S. D., Stebounova, L. V., Murry, D. J., Pufall, M. A., Ebert, S. M., Dyle, M. C., Bullard, S. A., Dierdorff, J. M., et al. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00472.2014 · Cited by 64

High throughput screening of mitochondrial bioenergetics in human differentiated myotubes identifies novel enhancers of muscle performance in aged mice

Biesemann, N., Ried, J. S., Ding‐Pfennigdorff, D., Dietrich, A., Rudolph, C., Hahn, S., Hennerici, W., Asbrand, C., Leeuw, T., & Strübing, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-27614-8 · Cited by 60

Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults

Messi, M. L., Li, T., Wang, Z.-M., Marsh, A. P., Nicklas, B. J., & Delbono, O. (2015) · The Journals of Gerontology Series A · doi:10.1093/gerona/glv176 · Cited by 58

Mitochondrial Quality Control in Sarcopenia: Updated Overview of Mechanisms and Interventions

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Adaptive Remodeling of the Neuromuscular Junction with Aging

Deschenes, M. R., Flannery, R. E., Hawbaker, A., Patek, L. G., & Mifsud, M. (2022) · Cells · doi:10.3390/cells11071150 · Cited by 63

High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state

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Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine

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Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy

Ebert, S. M., Rasmussen, B. B., Judge, A. R., Judge, S. M., Larsson, L., Wek, R. C., Anthony, T. G., Marcotte, G. R., Miller, M. J., Yorek, M. A., et al. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab440 · Cited by 64

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The translation of age-related body composition findings from rodents to humans

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool

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Skeletal Muscle Degeneration and Regeneration in Mice and Flies

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Effects of loaded voluntary wheel exercise on performance and muscle hypertrophy in young and old male C 57 B l/6 J mice

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Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4

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Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

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Regrowth after skeletal muscle atrophy is impaired in aged rats, despite similar responses in signaling pathways

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Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat

(2016)

Article of Significant Interest Selected from This Issue by the Editors

(2012) · Molecular and Cellular Biology · doi:10.1128/mcb.01541-12

Mitochondrial pathways and sarcopenia in the geroscience era

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Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice

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Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials

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