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Neuroinflammation and neurodegeneration in overnutrition-induced diseases

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Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis

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20 YEARS OF LEPTIN: Leptin at 20: an overview

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Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation

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Inhibition of PTP1B by Trodusquemine (MSI‐1436) Causes Fat‐specific Weight Loss in Diet‐induced Obese Mice

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Maternal pre‐pregnancy obesity and risk for inattention and negative emotionality in children

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20 YEARS OF LEPTIN: Connecting leptin signaling to biological function

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Leptin resistance in diet‐induced obesity: the role of hypothalamic inflammation

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Altered hypothalamic function in diet-induced obesity

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Leptin in Leanness and Obesity

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Protein-Tyrosine Phosphatase 1B Is Required for HER2/ Neu –Induced Breast Cancer

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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

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Leptin resistance: a prediposing factor for diet-induced obesity

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Leptin: molecular mechanisms, systemic pro-inflammatory effects, and clinical implications

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The Gut Microbiota Reduces Leptin Sensitivity and the Expression of the Obesity-Suppressing Neuropeptides Proglucagon (Gcg) and Brain-Derived Neurotrophic Factor (Bdnf) in the Central Nervous System

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Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance

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Brain insulin signalling in metabolic homeostasis and disease

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PTP1B and TCPTP – nonredundant phosphatases in insulin signaling and glucose homeostasis

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Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction

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Endoplasmic Reticulum Stress Induces Leptin Resistance

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Metabolic Pitfalls of CNS Cre-Based Technology

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Nonreceptor Protein-Tyrosine Phosphatases in Immune Cell Signaling

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The two faces of PTP1B in cancer

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PTP1B: A simple enzyme for a complex world

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CNS insulin signaling in the control of energy homeostasis and glucose metabolism – from embryo to old age

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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

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Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling

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AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity

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Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance

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Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons

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Leptin receptor signaling: pathways to leptin resistance

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The Leptin Receptor Complex: Heavier Than Expected?

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The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

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Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice

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Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B

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The role of leptin in health and disease

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Leptin and the Control of Body Weight: A Review of Its Diverse Central Targets, Signaling Mechanisms, and Role in the Pathogenesis of Obesity

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Hormone Interactions Regulating Energy Balance During Pregnancy

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Hypothalamic inflammation: a double‐edged sword to nutritional diseases

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Protein-tyrosine phosphatase 1B substrates and metabolic regulation

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Protein Tyrosine Phosphatase 1B (PTP1B) and Obesity

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Antidiabetic, Chemical, and Physical Properties of Organic Vanadates as Presumed Transition-State Inhibitors for Phosphatases

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The therapeutic potential of phosphatase inhibitors

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An expanded view of energy homeostasis: Neural integration of metabolic, cognitive, and emotional drives to eat

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Leptin and the brain: Influences on brain development, cognitive functioning and psychiatric disorders

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HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms

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Hypothalamic dysfunction in obesity

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Ursolic acid improves high fat diet-induced cognitive impairments by blocking endoplasmic reticulum stress and IκB kinase β/nuclear factor-κB-mediated inflammatory pathways in mice

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PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity

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Emerging Therapeutic Strategies for Obesity

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Adipokines in Obesity

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Diet-Induced Inflammation of the Hypothalamus in Obesity

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Mice with a Disruption of the Imprinted <i>Grb10</i> Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life

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In Brief

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Deficiency of PTP1B in Leptin Receptor-Expressing Neurons Leads to Decreased Body Weight and Adiposity in Mice

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Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action

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PTP1B Regulates Leptin Signal Transduction In Vivo

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Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B

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