The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Irritable bowel syndrome in the general population.
Open accessAbstract
OBJECTIVE: To determine the prevalence of symptoms compatible with a clinical diagnosis of irritable bowel syndrome in the general population. DESIGN: Validated postal questionnaire sent to 2280 subjects randomly selected in 10 year age bands from the lists of eight general practitioners. The Manning criteria were used to define irritable bowel syndrome. SETTING: Urban population in Southampton and mixed urban-rural population in Andover, Hampshire. RESULTS: A response of 71% yielded 1620 questionnaires for analysis, of which 412 (25%) reported more than six episodes of abdominal pain in the preceding year, with 350 (22%) reporting symptoms consistent with the diagnosis of irritable bowel syndrome. The male: female ratio was 1:1.38. More subjects with irritable bowel syndrome had constipation and diarrhoea and 35% with the syndrome reported rectal bleeding compared with an overall prevalence of 20%. Other symptoms and conditions including heartburn, dyspepsia, flushing, palpitations, migraine, and urinary symptoms were significantly more common in the group with irritable bowel syndrome. Abdominal pain in childhood was more common in the subjects with irritable bowel syndrome (12%) than without (3%). One third of the group with irritable bowel syndrome had sought medical advice during the study period (male:female ratio 1:1.21); consultation behaviour was influenced by age and the presence of associated symptoms, varied considerably among patients registered with different general practitioners, and was poorly correlated with symptom severity. CONCLUSION: Symptoms consistent with a diagnosis of irritable bowel syndrome are present in almost one quarter of the general population and tend to be associated with a number of other complaints and conditions, some of which may reflect smooth muscle dysfunction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Psychosocial Factors in the Irritable Bowel Syndrome
Drossman, D. A., McKee, D. C., Sandler, R. S., Mitchell, C. M., Cramer, E. M., Lowman, B. C., & Burger, A. L. (1988) · Gastroenterology · doi:10.1016/s0016-5085(88)80017-9 · Cited by 757
Non-colonic features of irritable bowel syndrome.
Whorwell, P. J., McCallum, M., Creed, F. H., & Roberts, C. T. (1986) · Gut · doi:10.1136/gut.27.1.37 · Cited by 473
Symptom complaints and health care seeking behavior in subjects with bowel dysfunction
Sandler, R. S., Drossman, D. A., Nathan, H. P., & McKee, D. C. (1984) · Gastroenterology · doi:10.1016/0016-5085(84)90706-6 · Cited by 326
Cited by
Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Lovell, R. M., & Ford, A. C. (2012) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2012.02.029 · Cited by 2,155
AGA technical review on irritable bowel syndrome.
Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.37095 · Cited by 1,384
Guidelines on the irritable bowel syndrome: mechanisms and practical management
Spiller, R., Aziz, Q., Creed, F., Emmanuel, A., Houghton, L., Hungin, P., Jones, R., Kumar, D., Rubin, G., Trudgill, N., et al. (2007) · Gut · doi:10.1136/gut.2007.119446 · Cited by 818
Self-citationMast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome
Barbara, G., Wang, B., Stanghellini, V., de Giorgio, R., Cremon, C., Di Nardo, G., Trevisani, M., Campi, B., Geppetti, P., Tonini, M., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2006.11.039 · Cited by 783
The role of psychological and biological factors in postinfective gut dysfunction
Gwee, K.-A., Leong, Y.-L., Graham, C., McKendrick, M. W., Collins, S. M., Walters, S. J., Underwood, J. E., & Read, N. W. (1999) · Gut · doi:10.1136/gut.44.3.400 · Cited by 764
Halpin, S. J., & Ford, A. C. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.260 · Cited by 607
SILK, D. B. A., DAVIS, A., VULEVIC, J., TZORTZIS, G., & GIBSON, G. R. (2009) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03911.x · Cited by 551
Akbar, A., Yiangou, Y., Facer, P., Walters, J. R. F., Anand, P., & Ghosh, S. (2008) · Gut · doi:10.1136/gut.2007.138982 · Cited by 526
Medical costs in community subjects with irritable bowel syndrome
Talley, N. J., Gabriel, S. E., Harmsen, W. S., Zinsmeister, A. R., & Evans, R. W. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90738-6 · Cited by 460
Rollman, G. B. (1995) · Pain Forum · doi:10.1016/s1082-3174(11)80026-7 · Cited by 399
Epidemiology and health care seeking in the functional GI disorders: a population-based study
Koloski, N. A., Talley, N. J., & Boyce, P. M. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05783.x · Cited by 371
Irritable bowel syndrome: A clinical review
Soares, R. L. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i34.12144 · Cited by 266
Predictors of health care seeking for irritable bowel syndrome: a population based study
Talley, N. J., Boyce, P. M., & Jones, M. (1997) · Gut · doi:10.1136/gut.41.3.394 · Cited by 250
Irritable bowel syndrome and surgery: A multivariable analysis☆
Longstreth, G. F., & Yao, J. F. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.02.020 · Cited by 248
Mearin, X. B. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520152584770 · Cited by 240
Ford, A. C., Forman, D., Bailey, A. G., Axon, A. T. R., & Moayyedi, P. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01740.x · Cited by 233
Efficacy of alosetron in irritable bowel syndrome: a meta‐analysis of randomized controlled trials
Cremonini, F., Delgado‐Aros, S., & Camilleri, M. (2003) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2003.00389.x · Cited by 219
Gender-related differences in IBS symptoms
Lee, O. Y., Mayer, E. A., Schmulson, M., Chang, L., & Naliboff, B. (2001) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03961.x · Cited by 228
van der Veek, P. P. J., van den Berg, M., de Kroon, Y. E., Verspaget, H. W., & Masclee, A. A. M. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.00257.x · Cited by 217
Boyce, P. M., Koloski, N. A., & Talley, N. J. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03197.x · Cited by 225
Kennedy, T. M., Jones, R. H., Hungin, A. P. S., O’Flanagan, H., & Kelly, P. (1998) · Gut · doi:10.1136/gut.43.6.770 · Cited by 199
Self-citationGwee, K.-A., Wee, S., Wong, M.-L., & J C Png, D. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04161.x · Cited by 190
Validation of a specific quality of life questionnaire for functional digestive disorders
Chassany, O., Marquis, P., Scherrer, B., Read, N. W., Finger, T., Bergmann, J. F., Fraitag, B., Geneve, J., & Caulin, C. (1999) · Gut · doi:10.1136/gut.44.4.527 · Cited by 180
Diagnostic utility of alarm features for colorectal cancer: systematic review and meta-analysis
Ford, A. C., Veldhuyzen van Zanten, S. J. O., Rodgers, C. C., Talley, N. J., Vakil, N. B., & Moayyedi, P. (2008) · Gut · doi:10.1136/gut.2008.159723 · Cited by 154
Talley, N. J., Boyce, P. M., & Jones, M. (1998) · Gut · doi:10.1136/gut.42.1.47 · Cited by 154
van Hemert, S., Breedveld, A. C., Rovers, J. M. P., Vermeiden, J. P. W., Witteman, B. J. M., Smits, M. G., & de Roos, N. M. (2014) · Frontiers in Neurology · doi:10.3389/fneur.2014.00241 · Cited by 150
HOUGHTON, L. A., HEYMAN, D. J., & WHORWELL, P. J. (1996) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.1996.tb00181.x · Cited by 141
Bowel Habit Subtypes and Temporal Patterns in Irritable Bowel Syndrome: Systematic Review
Guilera, M., Balboa, A., & Mearin, F. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40674.x · Cited by 131
Daley, A., Grimmett, C., Roberts, L., Wilson, S., Fatek, M., Roalfe, A., & Singh, S. (2008) · International Journal of Sports Medicine · doi:10.1055/s-2008-1038600 · Cited by 118
Ishaque, S. M., Khosruzzaman, S. M., Ahmed, D. S., & Sah, M. P. (2018) · BMC Gastroenterology · doi:10.1186/s12876-018-0788-9 · Cited by 109
Studying the Overlap Between IBS and GERD: A Systematic Review of the Literature
Nastaskin, I., Mehdikhani, E., Conklin, J., Park, S., & Pimentel, M. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9306-y · Cited by 98
Dear, K. L. E., Elia, M., & Hunter, J. O. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2570-4 · Cited by 97
Lovell, R. M., & Ford, A. C. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.336 · Cited by 95
Kennedy, T., Chalder, T., McCrone, P., Darnley, S., Knapp, M., Jones, R., & Wessely, S. (2006) · Health Technology Assessment · doi:10.3310/hta10190 · Cited by 92
Self-citationMüller-Lissner, S. (2003) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(03)00027-1 · Cited by 91
Proinflammatory Cytokine Gene Polymorphisms in Irritable Bowel Syndrome
Barkhordari, E., Rezaei, N., Ansaripour, B., Larki, P., Alighardashi, M., Ahmadi-Ashtiani, H. R., Mahmoudi, M., Keramati, M.-R., Habibollahi, P., Bashashati, M., et al. (2010) · Journal of Clinical Immunology · doi:10.1007/s10875-009-9342-4 · Cited by 78
Si, J.-M., Wang, L.-J., Chen, S.-J., Sun, L.-M., & Dai, N. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i7.1059 · Cited by 71
Emerging disease model for functional gastrointestinal disorders
Mayer, E. A. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00277-6 · Cited by 69
(2010) · PubMed · Cited by 65
Casiday, R. E., Hungin, A. P. S., Cornford, C. S., de Wit, N. J., & Blell, M. T. (2008) · Family Practice · doi:10.1093/fampra/cmn087 · Cited by 64
Psychosocial predictors of irritable bowel syndrome diagnosis and symptom severity
Phillips, K., Wright, B. J., & Kent, S. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.08.002 · Cited by 61
Rutter, C. L., & Rutter, D. R. (2007) · Journal of Health Psychology · doi:10.1177/1359105307071748 · Cited by 59
Prevalence of Irritable Bowel Syndrome in Chronic Fatigue
Gomborone, J., Gorard, D., Dewsnap, P., Libby, G., & Farthing, M. (1996) · Journal of the Royal College of Physicians of London · doi:10.1016/s0035-8819(25)00303-4 · Cited by 58
Irritable Bowel Syndrome and Chronic Pelvic Pain
Longstreth, G. F. (1994) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-199407000-00027 · Cited by 55
Long-term impact of irritable bowel syndrome: a qualitative study
Farndale, R., & Roberts, L. (2011) · Primary Health Care Research & Development · doi:10.1017/s1463423610000095 · Cited by 53
What are functional bowel disorders?
Zighelboim, J., & Talley, N. J. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)90293-l · Cited by 46
T-Helper 1, T-Helper 2, and T-Regulatory Cytokines Gene Polymorphisms in Irritable Bowel Syndrome
Barkhordari, E., Rezaei, N., Mahmoudi, M., Larki, P., Ahmadi-Ashtiani, H. R., Ansaripour, B., Alighardashi, M., Bashashati, M., Amirzargar, A. A., & Ebrahimi-Daryani, N. (2010) · Inflammation · doi:10.1007/s10753-010-9183-6 · Cited by 46
Gastroesophageal reflux disease and irritable bowel syndrome: A common overlap syndrome
Dickman, R., Feroze, H., & Fass, R. (2006) · Current Gastroenterology Reports · doi:10.1007/s11894-006-0045-1 · Cited by 26
Fedorak, R. N., Vanner, S. J., Paterson, W. G., & Bridges, R. J. (2012) · Canadian Journal of Gastroenterology · doi:10.1155/2012/861478 · Cited by 18
Patients with irritable bowel syndrome in primary care appear not to be heavy healthcare utilizers
FARESJÖ, Å., GRODZINSKY, E., FOLDEVI, M., JOHANSSON, S., & WALLANDER, M. ‐. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02815.x · Cited by 14
Metadata
- Authors
- Jones, R., & Lydeard, S.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1992-01-11
- Volume
- 304
- Issue
- 6819
- Pages
- 87-90
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2045032027
- Cited by
- 636
- References
- 3
- FWCI
- 29.91
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.