The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Measurement of gastrointestinal pH profiles in normal ambulant human subjects
Open accessAbstract
Gastrointestinal (GI) pH has been measured in 66 normal subjects using a pH sensitive radiotelemetry capsule passing freely through the gastrointestinal tract. Signals were recorded with a portable solid state receiver and recording system, enabling unconstrained measurements with normal ambulatory activities for up to 48 h during normal GI transit. Capsule position in the gut was monitored by surface location using a directional detector. Gastric pH was highly acidic (range 1.0-2.5) in all subjects. The mean pH in the proximal small intestine was 6.6 (0.5) for the first hour of intestinal recording. By comparison the mean pH in the terminal ileum was 7.5 (0.4) (p less than 0.001). In all subjects there was a sharp fall in pH to a mean of 6.4 (0.4) (p less than 0.001) as the capsule passed into the caecum. Values are means (SD). pH then rose progressively from the right to the left colon with a final mean value of 7.0 (0.7) (p less than 0.001).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This suggests that aNFC/AP cryogels can generally protect acid-sensitive drugs in the gastric environment while achieving rapid release in the healthy small intestine, typically at a pH of 6.5–7.5 [52].”
From Amidated Pectin/Nanocellulose Hybrid Cryogel System with a pH-Responsive Release Profile for Small Intestinal Delivery (2025) · cites this paper as [52]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Narisawa, T., Magadia, N. E., Weisburger, J. H., & Wynder, E. L. (1974) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/53.4.1093 · Cited by 704
A Handbook on Biotelemetry and Radio Tracking
(1980) · Elsevier eBooks · doi:10.1016/c2013-0-05926-9 · Cited by 540
Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats.
Reddy, B. S., Watanabe, K., Weisburger, J. H., & Wynder, E. L. (1977) · PubMed · Cited by 438
The geographical distribution of cancer.
Doll, R. (1969) · British Journal of Cancer · doi:10.1038/bjc.1969.1 · Cited by 251
Bown, R. L., Gibson, J., Sladen, G. E., Hicks, B. D., & Dawson, A. M. (1974) · Gut · doi:10.1136/gut.15.12.999 · Cited by 232
HIGH COLONIC pH PROMOTES COLORECTAL CANCER
THORNTON, J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92244-3 · Cited by 220
The effect of food on the gastrointestinal transit of pellets and an osmotic device (Osmet)
Davis, S. S., Hardy, J. G., Taylor, M. J., WHALLEY, D. R., & WILSON, C. G. (1984) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(84)90191-1 · Cited by 132
pH profile of gut as measured by radiotelemetry capsule.
Watson, B. W., Meldrum, S. J., Riddle, H. C., Brown, R. L., & Sladen, G. E. (1972) · BMJ · doi:10.1136/bmj.2.5805.104 · Cited by 111
Colonic release of 5‐amino salicylic acid from an oral preparation in active ulcerative colitis.
Dew, M. J., Ryder, R. E. J., Evans, N., Evans, B. K., & Rhodes, J. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb04983.x · Cited by 111
Branicki, F. J., Evans, D. F., Ogilvie, A. L., Atkinson, M. A., & Hardcastle, J. D. (1982) · Gut · doi:10.1136/gut.23.11.992 · Cited by 107
Self-citation
Flagged first, then by citations
Research works printed but not linked: 8
- Pietrousti A, Caprilli R, Guilano M, Serrano S, Vita S. Faecal pH in co!orectal cancer. ItalJ Gastroenterol 1985; 17: 88-91.
- Evans DF, Jones JA, Hardcastle JD. Ambulatory monitoring of gastrointestinal pH in man using a radiotelemetry capsule and a new solid state recorder. J Physiol 1985; 74: 4P.
- Ford PH, Pike GH. Decce series 4 user guide. Nottingham: Nottingham University Press, 1986.
- Da Cruz F. Kermit -A file transfer profile. Digital Press, 1984.
- Walker ARP, Walker BF, Segal I. Faecal pH value and its modification in S. African black and white schoolchildren. S Afr Med J 1979; 55: 495-8.
- Stower MJ, Hardcastle JD. Five year survival of 1,115 patients with colorectal cancer. J Clin Oncol 1985; 11: 119-23.
- Evans DF, Pye G, Bramley RB, Dyson TJ, Balfour TW, Hardcastle JD. Is colonic pH important in colorectal cancer? [Abstract]. Gut 1986; 27: A1257.
- Pye G, Crompton J, Evans DF, Clark AG, Hardcastle JD. The effect of dietary fibre supplementation on colonic pH in healthy volunteers. [Abstract] Gut 1987; 28: A 1366.
Cited by
Sorted by citations
Items 801–900 of 1,001
Haines, S., Gautheron, S., Nasser, W., & Renauld‐Mongénie, G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141469 · Cited by 12
Bombonnel, C., Vancaeyzeele, C., Guérin, G., & Vidal, F. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110495 · Cited by 12
Liu, Y., Horn, A. M. V., Pham, M. T. N., Dinh, B. N. N., Chen, R., Raphael, S. D. R., Paulino, A. J., Thaker, K., Somadder, A., Frost, D. J., et al. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.02096-23 · Cited by 11
Characterization of luminal contents from the fasted human proximal colon
Steigert, S., Brouwers, J., Verbeke, K., Vanuytsel, T., & Augustijns, P. (2024) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2024.106821 · Cited by 12
Mechanoadaptive Bioelectronics for Deep Tissue Sensing
Ren, X., Yuan, Y., Li, J., & Hu, B. (2024) · Chinese Journal of Chemistry · doi:10.1002/cjoc.202400879 · Cited by 11
Piao, H., Liu, S., Piao, H., Li, X., & Cui, F. (2012) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2012.707206 · Cited by 11
Newton, A. M. J., Prabakaran, L., & Jayaveera, K. (2012) · Asian Journal of Pharmaceutics · doi:10.4103/0973-8398.104832 · Cited by 11
Does Colonic Transit Time Affect Colonic pH?
Abbas, A. H., Wilding, G. E., Semler, J., & Sitrin, M. (2010) · The American Journal of Gastroenterology · doi:10.14309/00000434-201010001-00333 · Cited by 11
Monro, J. A., Mishra, S. S., & Hardacre, A. (2011) · Food Digestion · doi:10.1007/s13228-011-0009-2 · Cited by 11
The development andin vivoevaluation of a colon drug delivery system using human volunteers
Zimová, L., Vetchý, D., Muselík, J., & Štembírek, J. (2012) · Drug Delivery · doi:10.3109/10717544.2011.644350 · Cited by 11
Roine, J., Murtomaa, M., Myllys, M., & Salonen, J. (2012) · Journal of Electrostatics · doi:10.1016/j.elstat.2012.06.003 · Cited by 11
Wegeberg, A., Brock, C., Brock, B., Farmer, A. D., Hobson, A. R., Semler, J. R., & Scott, S. M. (2018) · Neurogastroenterology & Motility · doi:10.1111/nmo.13407 · Cited by 11
Preparation and Drug Release Properties of Nanostructured CaCO3 Porous Hollow Microspheres
Li, L., Zhu, Y., Cao, S., & Ma, M. (2009) · Journal of Inorganic Materials · doi:10.3724/sp.j.1077.2009.00166 · Cited by 11
Tang, T. B., Chen, H., & Murray, A. F. (2004) · IEE Proceedings - Nanobiotechnology · doi:10.1049/ip-nbt:20040213 · Cited by 11
Swelling and Ketoprofen Release Characteristics of Thermo- and pH-Responsive Copolymer Gels
Negishi, M., Hiroki, A., Horikoshi, Y., Miyajima, M., Asano, M., Katakai, R., & Yoshida, M. (1999) · Drug Development and Industrial Pharmacy · doi:10.1081/ddc-100102193 · Cited by 11
Gan, A., Kang, X., Goh, S. S., Wong, S. H., & Loo, S. C. J. (2025) · Journal of Functional Foods · doi:10.1016/j.jff.2025.106804 · Cited by 10
Hydrogel-based experimental models of the gastrointestinal tract
Sieders, M., Candry, P., & Aidy, S. E. (2025) · Microbiome · doi:10.1186/s40168-025-02208-5 · Cited by 12
Ngo, L. T., Cho, H., & Lee, Y. (2018) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2018.03.031 · Cited by 10
de Lemos, H., Prado, L. D., & Rocha, H. V. A. (2022) · Brazilian Journal of Pharmaceutical Sciences · doi:10.1590/s2175-97902022e19759 · Cited by 10
Preparation of nanodelivery systems for oral administration of low molecular weight heparin
Özemre, G. R., Kara, A. A., Pezik, E., Tort, S., Vural, İ., & Acartürk, F. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.104068 · Cited by 11
Freestanding region-responsive bilayer for functional packaging of ingestible devices
Straker, M. A., Levy, J. A., Stine, J. M., Borbash, V., Beardslee, L. A., & Reza Ghodssi, A. (2023) · Microsystems & Nanoengineering · doi:10.1038/s41378-023-00536-w · Cited by 10
Lipids in Oral Controlled Release Drug Delivery
Boyd, B. J., Nguyen, T., & Müllertz, A. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1004-1_15 · Cited by 10
Colon Targeting Using pH Sensitive Materials
Jain, A. (2018) · Advanced Research in Gastroenterology & Hepatology · doi:10.19080/argh.2018.08.555748 · Cited by 10
Gastrointestinal Delivery of APIs from Chitosan Nanoparticles
Sabra, R., & Billa, N. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.95363 · Cited by 10
Park, N.-Y., & Koh, A. (2022) · International Journal of Stem Cells · doi:10.15283/ijsc21243 · Cited by 10
Vambhurkar, G. B., Amulya, E., Sikder, A., Shah, S., Famta, P., Khatri, D. K., Singh, S. B., & Srivastava, S. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112816 · Cited by 10
Kovačič, N. N., Pišlar, M., Ilić, I. G., Mrhar, A., & Bogataj, M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.07.031 · Cited by 11
Ceruti, S., Dell’Era, S., Ruggiero, F., Bona, G., Glotta, A., Biggiogero, M., Tasciotti, E., Kronenberg, C., Lollo, G., & Saporito, A. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269024 · Cited by 10
Wiltink, E. H. H., Mulder, C. J. J., Stolk, L. M., Rietbroek, R. C., Verbeek, C., & Tytgat, G. N. J. (1990) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529009095533 · Cited by 10
Ileal mucosal absorption of bile acid in man: validation of a miniature flux chamber technique.
Hosie, K. B., DAVIE, R. J., Panagamuwa, B., Grobler, S., Keighley, M. R. B., & Birch, N. J. (1992) · Gut · doi:10.1136/gut.33.4.490 · Cited by 10
Kuang, J., Zheng, X., & Jia, W. P. (2024) · Protein & Cell · doi:10.1093/procel/pwae058 · Cited by 10
Tronel, A., Roger‐Margueritat, M., Plazy, C., Cunin, V., Mohanty, I., Dorrestein, P. C., Soranzo, T., & Gouëllec, A. L. (2025) · Metabolomics · doi:10.1007/s11306-025-02288-2 · Cited by 9
Tronel, A., Roger‐Margueritat, M., Plazy, C., Biennier, S., Craspay, A., Mohanty, I., Cools-Portier, S., Laiola, M., Roeselers, G., Mathieu, N., et al. (2025) · ISME Communications · doi:10.1093/ismeco/ycaf224 · Cited by 11
Yang, Y., Wang, X., Chen, G., Zhou, W., Zeng, X., Hu, B., Li, Y., & Huang, Q. (2018) · Food & Function · doi:10.1039/c8fo00563j · Cited by 9
Developmental Changes in Phosphate Homeostasis
MacDonald, T., Saurette, M., Beggs, M. R., & Alexander, R. T. (2020) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/112_2020_52 · Cited by 9
Efstathiou, S., Ma, C., Coursari, D., Patias, G., Al-Shok, L., Eissa, A. M., & Haddleton, D. M. (2022) · Polymer Chemistry · doi:10.1039/d2py00167e · Cited by 9
In vitroglucuronidation of aprepitant: a moderate inhibitor of UGT2B7
House, L. K., Ramı́rez, J., Seminerio, M. J., Mirkov, S., & Ratain, M. J. (2015) · Xenobiotica · doi:10.3109/00498254.2015.1038743 · Cited by 9
Mechanisms of antibiotic resistance and delivery strategies to prevent its emergence
Khoder, M., Tsapis, N., & Fattal, E. (2010) · Journal of Drug Delivery Science and Technology · doi:10.1016/s1773-2247(10)50072-8 · Cited by 9
Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency
Brock, A., Aldag, I., Edskes, S., Hartmann, M., Herzog, T., Uhl, W. H., & Schnekenburger, J. (2016) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000000720 · Cited by 9
Bawa, P., Choonara, Y. E., du Toit, L. C., Kumar, P., Ndesendo, V. M. K., Meyer, L. C. R., & Pillay, V. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.011 · Cited by 9
Khan, M. Z. I., Raušl, D., Radošević, S., Filić, D., Danilovski, A., Dumić, M., & Knežević, Z. (2006) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.58.11.0008 · Cited by 9
Li, J., Chai, H., Li, Y., Chai, X., Zhao, Y. H., Zhao, Y., Tao, T., & Xiang, X. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160260 · Cited by 9
Felicijan, T., Pišlar, M., Vene, K., & Bogataj, M. (2018) · AAPS PharmSciTech · doi:10.1208/s12249-018-1140-y · Cited by 9
Vroom, A., Barton, C. M., & Willian, K. R. (2020) · Journal of Chemical Education · doi:10.1021/acs.jchemed.9b00926 · Cited by 10
Sørensen, A., & Bukhave, K. (2010) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2010.06.002 · Cited by 9
Delivery, safety and efficacy of 5-aminosalicylate preparations
Bjarnason, I., & Macpherson, A. J. (1993) · Inflammopharmacology · doi:10.1007/bf02660618 · Cited by 9
Characterization of the pH-Dependent Disintegration of Chemically Modified Alginate Hydrogels
Morningstar, J. T., Alwan, A., Dixon, T., Opara, E. C., & Welker, M. E. (2025) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-024-00378-6 · Cited by 8
Islam, M. T., Chowdhury, R., Bhuia, M. S., Hasan, M. S. A., Akbor, M. S., Farhad, F., Domiciano, C. B., Silva, D. A. E., & Coutinho, H. D. M. (2025) · Pharmaceutical Science Advances · doi:10.1016/j.pscia.2025.100070 · Cited by 8
Electroactive ecosystem insights from corrosion microbiomes inform gut microbiome modulation
Jones, L. M., & Aidy, S. E. (2025) · The ISME Journal · doi:10.1093/ismejo/wraf112 · Cited by 9
Suzuki, S., Shirasaka, Y., Okada, R., Eguchi, A., Kishimoto, H., Langguth, P., & Inoue, K. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.05.006 · Cited by 9
On the feasibility of spray-dried eudragit-trehalose microparticles for enteric drug delivery
Karim, S. B., Ordoubadi, M., Wang, H., Gomez, M., & Vehring, R. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121264 · Cited by 8
Thin‐Plate Superstructures of the Immunogenic 33‐mer Gliadin Peptide
Herrera, M. G., Amundarain, M. J., Nicoletti, F., Drechsler, M., Costabel, M. D., Gentili, P. L., & Dodero, V. I. (2022) · ChemBioChem · doi:10.1002/cbic.202200552 · Cited by 8
A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles
Amekyeh, H., Sabra, R., & Billa, N. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s439975 · Cited by 9
Determination of consistency in pH of some commercial herbal formulations in Ghana
Kumadoh, D., Amekyeh, H., Archer, M.-A., Kyene, M. O., Yeboah, G. N., Brew-Daniels, H., Adi‐Dako, O., Osei-Asare, C., Adase, E., & Appiah, A. A. (2024) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2024.100876 · Cited by 8
Diurnal Variations in Digestion and Flow Drive Microbial Dynamics in the Gut
Salari, A., & Cremer, J. (2025) · PRX Life · doi:10.1103/prxlife.3.023012 · Cited by 9
Sweed, N. M., Basalious, E. B., & Nour, S. A. E.-K. (2019) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2019.1656737 · Cited by 8
Polymeric nanoparticles for controlled drug delivery
Sponchioni, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817838-6.00001-2 · Cited by 8
Radice, C., Korzekwa, K., & Nagar, S. (2022) · Drug Metabolism and Disposition · doi:10.1124/dmd.122.000831 · Cited by 8
Cherne, M. D., Gentry, A. B., Nemudraia, A., Nemudryi, A. A., Hedges, J. F., Grifka‐Walk, H. M., Blackwell, K., Snyder, D. T., Jerome, M. E., Madden, W. G., et al. (2022) · Gastro Hep Advances · doi:10.1016/j.gastha.2022.06.002 · Cited by 8
Cheng, K., Tsai, S., & Lin, W. (2003) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-003-1145-x · Cited by 8
Prodruggability of carbohydrates — oral FimH antagonists
Schönemann, W., Kleeb, S., Dätwyler, P., Schwardt, O., & Ernst, B. (2016) · Canadian Journal of Chemistry · doi:10.1139/cjc-2015-0582 · Cited by 8
Ma, R., Liu, F., Yap, S. F., Lee, H., Leong, R. W. L., Riordan, S. M., Grimm, M., & Zhang, L. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00896 · Cited by 8
Watanabe, K., Itoh, K., Park, S., Kaku, M., Ishii, K., Sasano, H., Naitoh, T., Unno, M., & Fukushima, K. (2020) · Surgery Today · doi:10.1007/s00595-020-01974-z · Cited by 8
Rebollar-Flores, J. E., Medina-Aparicio, L., Osio-Becerro, V. E., Villarreal, J. M., Mayo, S., Mendoza, B. D., Rodriguez-Gutierrez, S., Olvera, L., Dávila‐Ramos, S., Encarnación‐Guevara, S., et al. (2020) · Journal of Bacteriology · doi:10.1128/jb.00783-19 · Cited by 8
Zhang, Z., Wells, C. J. R., Davies, G., & Williams, G. R. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121155 · Cited by 8
The Role of Kinetics as Key Determinant in Toxicity of Pyrrolizidine Alkaloids and Their N-Oxides
Widjaja, F., Alhejji, Y., & Rietjens, I. M. C. M. (2021) · Planta Medica · doi:10.1055/a-1582-9794 · Cited by 8
Conditions for efficient alkaline storage of cover crops for biomethane production
van Vlierberghe, C., Escudié, R., Bernet, N., Santa‐Catalina, G., Frédéric, S., & Carrère, H. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.126722 · Cited by 8
Zeybek, N., Büyükkileci, A. O., Güleç, Ş., Polat, M., & Polat, H. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.103983 · Cited by 8
Molecularly Imprinted Polymers
Peeters, M., Eersels, K., Junkers, T., & Wagner, P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801301-4.00013-x · Cited by 8
Hadi, M. A. (2015) · Scientia Pharmaceutica · doi:10.3797/scipharm.1503-16 · Cited by 8
El-Hanboushy, S., El‐Rahman, M. K. A., Fayez, Y. M., LOTFY, H. M., & Abdelkawy, M. A. A. (2019) · Journal of The Electrochemical Society · doi:10.1149/2.0741908jes · Cited by 8
Broesder, A., Kosta, A.-M. M. A. C., Woerdenbag, H. J., Nguyen, D. N., Frijlink, H. W., & Hinrichs, W. L. J. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.06.012 · Cited by 8
Optimizing gastrointestinal delivery of drugs
Wilding, I. R., Davis, S. S., & O’Hagan, D. T. (1994) · Baillière s Clinical Gastroenterology · doi:10.1016/0950-3528(94)90004-3 · Cited by 8
Novel Combinations of Rate-Controlling Polymers for the Release of Leuprolide Acetate in the Colon
Prabhu, S. V., Kanthamneni, N., & Ma, C. (2008) · Drug Delivery · doi:10.1080/10717540801905157 · Cited by 8
Variability, Uncertainty, and Sensitivity Analysis
(2012) · Wiley eBooks · doi:10.1002/9781118140291.ch8 · Cited by 8
Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
Kensuke, A., & Kazutaka, I. (2019) · Worldwide Protein Data Bank · doi:10.2210/pdb6j5l/pdb · Cited by 8
Jačić, J. K., Dimitrijević, M., Bajuk‐Bogdanović, D., Stanković, D. M., Savić, S., Spasojević, I., & Milenković, M. R. (2023) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-023-02018-w · Cited by 7
Chen, P., Wang, Y., Cai, Z., & Lu, X. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.142841 · Cited by 7
Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility
Rispal, J., Garcia, J. R., Palikuqi, B., Vegesna, M., Vaka, D., Kang, S., Trentesaux, C., Du, J., Realini, N. R., Vega, P. N., et al. (2026) · Cell · doi:10.1016/j.cell.2026.02.007 · Cited by 7
Bowel transit studies in children: evidence base, role and practicalities
Popescu, M., & Mutalib, M. (2021) · Frontline Gastroenterology · doi:10.1136/flgastro-2020-101719 · Cited by 7
An engineered genetic circuit for lactose intolerance alleviation
Cheng, M., Cheng, Z., Yu, Y., Liu, W., Li, R., Guo, Z., Qin, J., Zeng, Z., Di, L., Mo, Y., et al. (2021) · BMC Biology · doi:10.1186/s12915-021-01070-9 · Cited by 7
Jain, S., Kumar, V., Koul, A., Singh, A. K., & Sandal, N. (2023) · BioMetals · doi:10.1007/s10534-023-00508-7 · Cited by 7
Woodward, S. E., Neufeld, L. M. P., Peña-Díaz, J., Feng, W., Serapio-Palacios, A., Tarrant, I., Deng, W., & Finlay, B. B. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002761 · Cited by 7
Ben‐Haim, A. E., Shalev, N., Amalraj, A. J. J., Zelinger, E., Mani, K. A., Belausov, E., Shoval, I., Nativ‐Roth, E., Maria, R., Atkins, A., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.140822 · Cited by 7
Development of pressure-sensitive dosage forms with a core liquefying at body temperature
Wilde, L., Bock, M., Wolf, M., Glöckl, G., Garbacz, G., & Weitschies, W. (2013) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2013.12.008 · Cited by 7
Infer Metagenomic Abundance and Reveal Homologous Genomes Based on the Structure of Taxonomy Tree
Qiu, Y., Tian, X., & Zhang, S. (2015) · IEEE Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2015.2415814 · Cited by 7
Ayele, G. T., Monfray, S., Bœuf, F., Cloarec, J., Ecoffey, S., Drouin, D., Puyoo, E., & Souifi, A. (2017) · European Solid-State Device Research Conference · doi:10.1109/essderc.2017.8066642 · Cited by 7
Premilling pearling for producing wheat fractions with distinct digestibility and fermentability
Brier, N. D., Lemmens, E., Gomand, S. V., Verbeke, K., & Delcour, J. A. (2021) · Cereal Chemistry · doi:10.1002/cche.10419 · Cited by 7
Kono, T., Maejima, T., Ono, Y., Ito, T., Furukawa, S., Nishiyama, M., Yamamoto, M., Sugitani, A., Karasaki, H., Mizukami, Y., et al. (2022) · Gene · doi:10.1016/j.gene.2022.146266 · Cited by 7
Salem, M. B., Aiche, G., Haddab, Y., Rubbert, L., & Renaud, P. (2022) · Journal of Medical Devices · doi:10.1115/1.4055250 · Cited by 7
Liu, Y., Zhang, X., Meng, C., Ji, S., & Guo, K. (2022) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2022.2151016 · Cited by 7
Predicting Food Effects on Oral Extended-Release Drug Products: A Retrospective Evaluation
Zou, P., Vaidyanathan, J., Tran, D. C., Raines, K., Chatterjee, P., Madabushi, R., & Seo, S. K. (2023) · The AAPS Journal · doi:10.1208/s12248-023-00804-7 · Cited by 7
Bioavailability of AREDS1 micronutrients from softgel capsules and tablets: a pilot study.
Johnson, E. J., Vishwanathan, R., Rasmussen, H., & Lang, J. C. (2014) · Europe PMC (PubMed Central) · Cited by 7
Roldo, M., Barbu, E., Brown, J. F., Laight, D. W., Smart, J. D., & Tsibouklis, J. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30810 · Cited by 7
Soil-Transmitted Helminths: Does Nutrition Make a Difference?
Scott, M. E., & Koski, K. G. (2020) · Springer eBooks · doi:10.1007/978-3-030-56913-6_12 · Cited by 7
Sakuma, S., 小倉, 涼., Masaoka, Y., Kataoka, M., Tanno, F. K., Kokubo, H., & Yamashita, S. (2009) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21716 · Cited by 7
Activity, stability and folding analysis of the chitinase from Entamoeba histolytica
Muñoz-Muñoz, P. L. A., Minchaca, A. Z., Mares, R. E., & Ramos, M. A. (2015) · Parasitology International · doi:10.1016/j.parint.2015.10.006 · Cited by 7
Theismann, E., Keppler, J. K., Knipp, J.-R., Fangmann, D., Appel, E., Gorb, S. N., Waetzig, G. H., Schreiber, S., Laudes, M., & Schwarz, K. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.04.039 · Cited by 9
Monney, B., Dibble, A. G., Moatsou, D., & Weder, C. (2020) · ACS Omega · doi:10.1021/acsomega.9b04336 · Cited by 7
Gareb, B., Beugeling, M., Posthumus, S., Otten, A. T., Dijkstra, G. D. H., Kosterink, J. G. W., & Frijlink, H. W. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102552 · Cited by 7
Metadata
- Authors
- Evans, D. F., Pye, G., Bramley, R., Clark, A. G., Dyson, T. J., & Hardcastle, J. D.
- Affiliations
- Queen's Medical Centre (GB)
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1988-08
- Volume
- 29
- Issue
- 8
- Pages
- 1035-1041
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC1433896
- OpenAlex
- W2089407496
- Cited by
- 1,240
- References
- 23
- Citations by year
- 2026: 38 · 2025: 74 · 2024: 52 · 2023: 67 · 2022: 70 · 2021: 84 · 2020: 67 · 2019: 58 · 2018: 47 · 2017: 55 · 2016: 49 · 2015: 59 · 2014: 67 · 2013: 43 · 2012: 56
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Chemistry and Sensors
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Keywords
- gastrointestinal pH, gastric pH, terminal ileum, cecum, colon, ambulatory pH monitoring, gastrointestinal transit, normal subjects
- MeSH terms
- Adult, Aged, Aged, 80 and over, Female, Gastrointestinal Contents, Humans, Hydrogen-Ion Concentration, Male, Middle Aged, Reference Values
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review