Cited by 156Probiotics and Fermented FoodsGastrointestinal motility and disordersGut microbiota and health

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A prospective randomised study of the probiotic Lactobacillus plantarum 299V on indices of gut barrier function in elective surgical patients

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McNaught, C E, Woodcock, N P, MacFie, J, Mitchell, C J·2002·Gut

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Abstract

Background: Bacterial translocation occurs in surgical patients and may predispose to postoperative septic morbidity. Many factors are thought to influence the prevalence of bacterial translocation, one of which is the composition of the gut microflora. The aim of this prospective and randomised study was to assess the effect of the probiotic Lactobacillus plantarum 299v on the incidence of bacterial translocation, gastric colonisation, and septic complications in elective surgical patients. Methods: Patients undergoing elective major abdominal surgery were randomised to either a treatment or control group. The treatment group received an oral preparation containing Lactobacillus plantarum 299v ( Proviva ) for at least one week preoperatively and also in the postoperative period. Bacterial translocation was determined by culture of a mesenteric lymph node and serosal scraping obtained at laparotomy. Gastric colonisation was assessed by microbiological culture of nasogastric aspirates. All postoperative septic complications were recorded. Results: A total of 129 patients completed the study (probiotic group n=64). There was no significant difference between the two groups in terms of bacterial translocation (12% v 12%; p=0.82), gastric colonisation with enteric organisms (11% v 17%; p=0.42), or septic morbidity (13% v 15%; p=0.74). Conclusions: Administration of Lactobacillus plantarum 299v in elective surgical patients does not influence the rate of bacterial translocation, gastric colonisation, or incidence of postoperative septic morbidity.

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Probiotics in man and animals
AFRC, R. F. (1989) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1989.tb05105.x · Cited by 4,831
Manual for the identification of medical bacteria.
Cowan, S. T., & Steel, K. (1965) · Cambridge University Press eBooks · Cited by 4,823
POSSUM: A scoring system for surgical audit
Copeland, G. P., Jones, D., & Walters, M. (1991) · British journal of surgery · doi:10.1002/bjs.1800780327 · Cited by 1,716
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial
Gionchetti, P., Rizzello, F., Venturi, A., Brigidi, P., Matteuzzi, D., Bazzocchi, G., Poggioli, G., Miglioli, M., & Campieri, M. (2000) · Gastroenterology · doi:10.1053/gast.2000.9370 · Cited by 1,485
Probiotics in man and animals.
Fuller, R. (1989) · PubMed · Cited by 1,292
Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial
Rembacken, B., Snelling, A. M., Hawkey, P. M., Chalmers, D. M., & Axon, A. (1999) · The Lancet · doi:10.1016/s0140-6736(98)06343-0 · Cited by 1,100
Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus
Saavedra, J. M., Bauman, N. A., Perman, J. A., Yolken, R. H., Saavedra, J. M., Bauman, N. A., & Oung, I. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91708-6 · Cited by 958
Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression
Mack, D. R., Michail, S. K., Wei, S. H., McDougall, L., & Hollingsworth, M. A. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.276.4.g941 · Cited by 839
Double‐blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis
Kruis, W., SCHÜTZ, E., Fric, P., Fixa, B., Judmaier, G., & Stolte, M. (1997) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1997.00225.x · Cited by 774
Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria.
Bernet‐Camard, M., Brassart, D., Neeser, J., & Servin, A. L. (1994) · Gut · doi:10.1136/gut.35.4.483 · Cited by 751

Show all 30 references

Research works printed but not linked: 4

1991, Br J Surg, 78, 356
1999, Am J Physiol, 276, G941
10.1002/bjs.1800841005 · DOI
2000, Care Crit Ill, 16, 6

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Authors: McNaught, C. E., Woodcock, N. P., MacFie, J., & Mitchell, C. J.
Affiliations: Scarborough General Hospital (GB)
Corresponding author: MacFie, J
ORCID: MacFie, J
Mitchell, C J
Venue: Gut
Publisher: BMJ
Published: 2002-12
Volume: 51
Issue: 6
Pages: 827-831
ISSN: 0017-5749 (ISSN-L)
1468-3288
DOI: 10.1136/gut.51.6.827
PMC: PMC1773461
OpenAlex: W2156266318
Cited by: 156
References: 30
Citations by year: 2026: 3 · 2025: 1 · 2024: 3 · 2023: 5 · 2022: 1 · 2021: 7 · 2020: 4 · 2019: 7 · 2018: 5 · 2017: 6 · 2016: 4 · 2015: 10 · 2014: 4 · 2013: 11 · 2012: 8
FWCI: 13.01
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Gut (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: Lactobacillus plantarum 299v, probiotics, bacterial translocation, intestinal barrier, postoperative sepsis, elective abdominal surgery, mesenteric lymph nodes, gut microbiota
MeSH terms: Adult, Aged, Bacterial Infections, C-Reactive Protein, Female, Gastric Mucosa, Humans, Intestinal Mucosa, Lactobacillus, Lymph Nodes, Male, Middle Aged, Postoperative Complications, Preoperative Care, Prospective Studies, Chi-Square Distribution, Statistics, Nonparametric, Bacterial Translocation, Probiotics

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A prospective randomised study of the probiotic Lactobacillus plantarum 299V on indices of gut barrier function in elective surgical patients

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