Subclinical left ventricular dysfunction in normotensive women with Turner’s syndrome
Open accessAbstract
Objective A qualitative study performed with a cross-sectional survey to report staff perceptions on emergency department (ED) communication while trialling a personal hands-free wireless communication device (WCD) between August and October 2008 in a busy inner city ED. Method A survey of all Royal London Hospital ED staff was conducted pre and post-implementation of a personal WCD. The survey included responses to occupation, experience, communication modes, communication wait times, perceived interruptions at the bedside and general perceptions of communication efficiency. Results No appreciable change in communication modes or perceived waiting times was reported No increase in bedside interruptions were reported. An overwhelming number of respondents considered the system had contributed significantly to improving the quality of the work environment, patient safety and care. Conclusion This study correlated with others showing a very strong perception of improved communication and working environment: less noise, better handovers and improved staff resource use. The study adds to the limited number of published trials examining WCD in health care. Observational reports post-implementation were overwhelmingly positive. Quantitative studies measuring the impact on patient flow, safety and cost benefits should be considered.
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Left ventricular hypertrophy and increased ventricular mass are commonly observed in TS, even in those who do not have a diagnosis of hypertension.
“Left ventricular hypertrophy and increased ventricular mass are commonly observed in TS, even in those who do not have a diagnosis of hypertension.460,461”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [460]
Cites
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“Women with Turner’s syndrome (TS) are at risk of not only congenital cardiovascular malformations but also hypertension and ischaemic heart disease,”
BackgroundOstberg, J. E., Brookes, J. A. S., McCarthy, C., Halcox, J., & Conway, G. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1090 · Cited by 146 · see citing works
Nocturnal hypertension and impaired sympathovagal tone in Turner syndrome
Gravholt, C. H., Hansen, K. W., Erlandsen, M., Ebbehøj, E., & Christiansen, J. S. (2006) · Journal of Hypertension · doi:10.1097/01.hjh.0000200509.17947.0f · Cited by 90 · see citing works
Self-citationElsheikh, M., Bird, R., Casadei, B., Conway, G. S., & Wass, J. A. H. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.2.6384 · Cited by 86 · see citing works
Left ventricular dysfunction in hypertensive patients with Type 2 diabetes mellitus
Andersen, N. H., Poulsen, S. H., Poulsen, P. L., Knudsen, S. T., Helleberg, K., Hansen, K. W., Berg, T. J., Flyvbjerg, A., & Mogensen, C. E. (2005) · Diabetic Medicine · doi:10.1111/j.1464-5491.2005.01589.x · Cited by 60 · see citing works
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Gravholt, C. H., Andersen, N. H., Conway, G. S., Dekkers, O. M., Geffner, M. E., Klein, K. O., Lin, A. E., Mauras, N., Quigley, C. A., Rubin, K., et al. (2017) · European Journal of Endocrinology · doi:10.1530/eje-17-0430 · Cited by 1,101 · see citing works
Self-citationClinical practice guidelines for the care of girls and women with Turner syndrome.
Gravholt, C. H., Andersen, N. H., Christin-Maitre, S., Davis, S. M., Duijnhouwer, A., Gawlik, A., Maciel-Guerra, A. T., Gutmark-Little, I., Fleischer, K., Hong, D., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae050 · Cited by 224 · see citing works
Self-citationCardiovascular imaging in Turner syndrome: state-of-the-art practice across the lifespan
Mortensen, K. H., Young, L., De Backer, J., Silberbach, M., Collins, R. T., Duijnhouwer, A. L., Pandya, B., Gravholt, C. H., Lopez, L., & Roos-Hesselink, J. W. (2018) · Heart · doi:10.1136/heartjnl-2017-312658 · Cited by 35 · see citing works
Self-citationWen, J., Trolle, C., Viuff, M. H., Ringgaard, S., Laugesen, E., Gutmark, E. J., Subramaniam, D. R., Backeljauw, P., Gutmark-Little, I., Andersen, N. H., et al. (2018) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-018-0497-0 · Cited by 35 · see citing works
Self-citationBrun, S., Cleemann, L., Holm, K., Salskov, G., Erlandsen, M., Berglund, A., Andersen, N. H., & Gravholt, C. H. (2019) · Hypertension · doi:10.1161/hypertensionaha.118.11742 · Cited by 24 · see citing works
Self-citationLeft ventricular thickness is increased in nonhypertensive Turner's syndrome
Sozen, A. B., Cefle, K., Kudat, H., Ozturk, S., Oflaz, H., Akkaya, V., Palanduz, S., Demirel, S., Ozcan, M., Goren, T., et al. (2009) · Echocardiography · doi:10.1111/j.1540-8175.2009.00902.x · Cited by 19 · see citing works
Left ventricular hypertrophy in Turner syndrome: a prospective echocardiographic study
Mortensen, K. H., Gravholt, C. H., Hjerrild, B. E., Stochholm, K., & Andersen, N. H. (2012) · Echocardiography · doi:10.1111/j.1540-8175.2012.01754.x · Cited by 15 · see citing works
Self-citationHypertension in Turner syndrome: a review of proposed mechanisms, management and new directions
Jones, L., Blair, J., Hawcutt, D. B., Lip, G. Y. H., & Shantsila, A. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003321 · Cited by 13 · see citing works
The prevalence of hypertension in paediatric Turner syndrome: a systematic review and meta-analysis
McCarrison, S., Carr, A., Wong, S. C., & Mason, A. (2022) · Journal of Human Hypertension · doi:10.1038/s41371-022-00777-8 · Cited by 9 · see citing works
“Lack of this normal mechanism, termed ‘non-dipper’, has been associated with increased morbidity and is likely to play a part in the end-organ damage, including left ventricular hypertrophy observed in ‘normotensive’ women with TS [49, 50].”
BackgroundPeppa, M., Pavlidis, G., Mavroeidi, I., Katogiannis, K., Varoudi, M., Thymis, J., Kostelli, G., Vlastos, D., Plotas, P., Bamias, A., et al. (2021) · Journal of Hypertension · doi:10.1097/hjh.0000000000002903 · Cited by 7 · see citing works
- Authors
- Andersen, N. H., Hjerrild, B. E., Sørensen, K., Pedersen, E. M., Stochholm, K., Gormsen, L. C., Hørlyck, A., Christiansen, J. S., & Gravholt, C. H.
- Affiliations
- Aarhus University Hospital (DK)
- Corresponding author
- Gravholt, C H
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2006-09-14
- Volume
- 92
- Issue
- 10
- Pages
- 1516-1517
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1861017
- OpenAlex
- W2137618904
- Cited by
- 36
- References
- 5
- Citations by year
- 2025: 2 · 2024: 2 · 2022: 2 · 2021: 4 · 2019: 4 · 2018: 4 · 2017: 2 · 2016: 1 · 2013: 3 · 2012: 3
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Novo Nordisk
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- Turner syndrome, subclinical left ventricular dysfunction, normotensive women, women's cardiovascular health, left ventricular function
- MeSH terms
- Adult, Blood Flow Velocity, Blood Pressure, Female, Heart Rate, Humans, Turner Syndrome, Echocardiography, Doppler, Ventricular Dysfunction, Left
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