Standing-based office work shows encouraging signs of attenuating post-prandial glycaemic excursion
Open accessAbstract
OBJECTIVES: The main aim of this study was to compare two days of continuous monitored capillary blood glucose (CGM) responses to sitting and standing in normally desk-based workers. DESIGN, SETTING AND PARTICIPANTS: This open repeated-measures study took place in a real office environment, during normal working hours and subsequent CGM overnight measures in 10 participants aged 21-61 years (8 female). MAIN OUTCOMES: Postprandial (lunch) measures of: CGM, accelerometer movement counts (MC) heart rate, energy expenditure (EE) and overnight CGM following one afternoon of normal sitting work compared with one afternoon of the same work performed at a standing desk. RESULTS: Area-under-the-curve analysis revealed an attenuated blood glucose excursion by 43% (p=0.022) following 185 min of standing (143, 95% CI 5.09 to 281.46 mmol/L min) compared to sitting work (326; 95% CI 228 to 425 mmol/L min). Compared to sitting, EE during an afternoon of standing work was 174 kcals greater (0.83 kcals/min; p=0.028). The accelerometer MC showed no differences between the afternoons of seated versus standing work; reported differences were thus a function of the standing work and not from additional physical movements around the office. CONCLUSIONS: This is the first known 'office-based' study to provide CGM measures that add some of the needed mechanistic information to the existing evidence-base on why avoiding sedentary behaviour at work could lead to a reduced risk of cardiometabolic diseases.
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One study using continuous glucose monitors found blood sugars after standing for an afternoon of 185 minutes were reduced by 43% compared with sitting.
“One study utilizing continuous glucose monitors found blood sugars after standing for an afternoon (185 minutes) was reduced by 43% in those standing compared to sitting.”
From The Impact of Physical Activity in Patients With Type 2 Diabetes (2025) · cites this paper as [87]
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- Authors
- Buckley, J. P., Mellor, D. D., Morris, M., & Joseph, F.
- Affiliations
- University of Chester (GB)
- University of Nottingham (GB)
- Countess of Chester Hospital NHS Foundation Trust (GB)
- Corresponding author
- Buckley, John P
- Venue
- Occupational and Environmental Medicine
- Publisher
- BMJ
- Published
- 2013-12-02
- Volume
- 71
- Issue
- 2
- Pages
- 109-111
- ISSN
- 0007-1072 (ISSN-L)
- 1351-0711
- 1470-7926
- OpenAlex
- W2168710749
- Cited by
- 124
- References
- 12
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 9 · 2019: 12 · 2018: 19 · 2017: 25 · 2016: 17 · 2015: 17 · 2014: 11
- FWCI
- 10.42
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- cc-by
- Locations
- Occupational and Environmental Medicine (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion, cc-by)
- HighWire Press Open Archive (submittedVersion)
- Funders
- University of Chester
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Social Sciences › Psychology › Social Psychology › Ergonomics and Musculoskeletal Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- standing work, sitting work, blood glucose, energy expenditure, sedentary behavior, office workers, continuous glucose monitoring, cardiometabolic risk
- MeSH terms
- Adult, Blood Glucose, Energy Metabolism, Female, Humans, Male, Middle Aged, Posture, Workplace, Area Under Curve, Young Adult, Sedentary Behavior
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