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The role of DXA bone density scans in the diagnosis and treatment of osteoporosis
Open accessAbstract
Dual energy x ray absorptiometry (DXA) scans to measure bone mineral density (BMD) at the spine and hip have an important role in the evaluation of individuals at risk of osteoporosis, and in helping clinicians advise patients about the appropriate use of antifracture treatment. Compared with alternative bone densitometry techniques, hip and spine DXA examinations have a number of advantages that include a consensus that BMD results can be interpreted using the World Health Organization T-score definition of osteoporosis, a proven ability to predict fracture risk, proven effectiveness at targeting antifracture therapies, and the ability to monitor response to treatment. This review discusses the evidence for these and other clinical aspects of DXA scanning, including its role in the new WHO algorithm for treating patients on the basis of their individual fracture risk.
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“Currently, the diagnosis of osteoporosis primarily relies on the assessment of bone mass through bone densitometry, also known as dual-energy X-ray absorptiometry (DEXA) [46].”
From Osteoporosis: Molecular Pathology, Diagnostics, and Therapeutics (2023) · cites this paper as [46]
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Mohammadi, A., Hedayati, R., & Sadighi, M. (2025) · International Journal for Numerical Methods in Biomedical Engineering · doi:10.1002/cnm.70122
Øyen, J. (2011) · NORA - Norwegian Open Research Archives
Lu, T., Forgetta, V., Keller‐Baruch, J., Nethander, M., Bennett, D., Forest, M., Bhatnagar, S., Walters, R. G., Lin, K., Chen, Z., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13710811
Akil, S., Al-Mohammed, H., Al-Batati, N., Tirsen, M., Al-Otaibi, A., AlZahrani, A., Bakhder, D., AlSubaie, R., & AbuAlsaud, S. (2021) · Figshare · doi:10.6084/m9.figshare.16909870
Tayyab, M., Ahmad, M., Akbar, R., Syed, R., Ullah, K. I., Haq, N. U., Khan, I., Khan, A. A., Khan, A., & Javaid, M. H. (2025) · Cureus · doi:10.7759/cureus.98776
“Secondary outcomes included changes in BMD [17] of the proximal femur, bone turnover markers (procollagen type I N-terminal propeptide (PINP), β -C-terminal telopeptide ( β -CTX), and N-terminal mid-fragment of osteocalcin (N-MID osteocalcin)) [18], and the incidence of adverse events such as…”
Osteoporosis Detection From Dental Periapical Radiographs Using Deep Learning Approaches
Bhat, S., & Shanthi, P. B. (2026) · IEEE Access · doi:10.1109/access.2026.3658368
Metadata
- Authors
- Blake, G. M., & Fogelman, I.
- Affiliations
- King's College London (GB)
- Corresponding author
- Blake, Glen M
- ORCID
- Blake, Glen M
- Venue
- Postgraduate Medical Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-08-01
- Volume
- 83
- Issue
- 982
- Pages
- 509-517
- ISSN
- 0032-5473 (ISSN-L)
- 1469-0756
- PMC
- PMC2600106
- OpenAlex
- W2000878199
- Cited by
- 532
- References
- 74
- Citations by year
- 2026: 31 · 2025: 55 · 2024: 56 · 2023: 34 · 2022: 55 · 2021: 54 · 2020: 31 · 2019: 31 · 2018: 33 · 2017: 26 · 2016: 22 · 2015: 16 · 2014: 19 · 2013: 22 · 2012: 13
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Postgraduate Medical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Keywords
- dual-energy X-ray absorptiometry, bone mineral density, osteoporosis diagnosis, fracture risk prediction, treatment response monitoring
- MeSH terms
- Humans, Osteoporosis, Risk Factors, Absorptiometry, Photon, Bone Density, Risk Assessment, Fractures, Bone
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