Regulation Mechanisms and Signaling Pathways of Autophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Kominami, E., Ohsumi, Y., & Yoshimori, T. (2000) · The EMBO Journal · doi:10.1093/emboj/19.21.5720 · Cited by 6,605

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914

Autophagy as a Regulated Pathway of Cellular Degradation

Klionsky, D. J., & Emr, S. D. (2000) · Science · doi:10.1126/science.290.5497.1717 · Cited by 3,630

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082

Mitochondria in lung diseases

Aravamudan, B., Thompson, M. A., Pabelick, C. M., & Prakash, Y. S. (2013) · Expert Review of Respiratory Medicine · doi:10.1586/17476348.2013.834252 · Cited by 89

Neuronal Autophagy as a Mediator of Life and Death

Puyal, J., Ginet, V., Grishchuk, Y., Truttmann, A. C., & Clarke, P. G. H. (2011) · The Neuroscientist · doi:10.1177/1073858411404948 · Cited by 89

TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice

Kökten, T., Gibot, S., Lepage, P., D’Alessio, S., Hablot, J., Ndiaye, N. C., Busby-Venner, H., Monot, C., Garnier, B., Moulin, D., et al. (2017) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjx129 · Cited by 89

Targeting EGFR‐mediated autophagy as a potential strategy for cancer therapy

Sooro, M. A., Zhang, N., & Zhang, P. (2018) · International Journal of Cancer · doi:10.1002/ijc.31398 · Cited by 88

Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer

Park, K. C., Paluncic, J., Kovačević, Ž., & Richardson, D. R. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.05.020 · Cited by 88

Build-UPS and break-downs: metabolism impacts on proteostasis and aging

Ottens, F., Franz, A., & Hoppe, T. (2021) · Cell Death and Differentiation · doi:10.1038/s41418-020-00682-y · Cited by 88

Regulated cell death in acute myocardial infarction: Molecular mechanisms and therapeutic implications

Zhu, L., Liu, Y., Wang, K., & Wang, N. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102629 · Cited by 89

Autophagic LC3B overexpression correlates with malignant progression and predicts a poor prognosis in hepatocellular carcinoma

Wu, D., Jia, C., Chen, J., Lin, Z., Ruan, D., Li, X., Lin, Q., Min‐Dong, Ma, X., Wan, X., et al. (2014) · Tumor Biology · doi:10.1007/s13277-014-2531-7 · Cited by 88

Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure

Hashem, S. I., Perry, C. N., Bauer, M., Han, S. J., Clegg, S. D., Ouyang, K., Deacon, D. C., Spinharney, M., Panopoulos, A. D., Belmonte, J. C. I., et al. (2015) · Stem Cells · doi:10.1002/stem.2015 · Cited by 88

Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia

Sumitomo, Y., Koya, J., Nakazaki, K., Kataoka, K., Tsuruta-Kishino, T., Morita, K., Sato, T., & Kurokawa, M. (2016) · Blood · doi:10.1182/blood-2015-12-684696 · Cited by 89

Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Ghosh, A. K., Mau, T., O’Brien, M., Garg, S., & Yung, R. L. (2016) · Aging · doi:10.18632/aging.101083 · Cited by 88

Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases

Wang, S.-F., Wu, M.-Y., Cai, C.-Z., Li, M., & Lu, J. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.10.069 · Cited by 88

Using Drosophila as an integrated model to study mild repetitive traumatic brain injury

Barekat, A., Gonzalez, A., Mauntz, R. E., Kotzebue, R. W., Molina, B., El-Mecharrafie, N., Conner, C. J., Garza, S., Melkani, G. C., Joiner, W. J., et al. (2016) · Scientific Reports · doi:10.1038/srep25252 · Cited by 87

Novel Role of Silent Information Regulator 1 in Myocardial Ischemia

Yang, Y., Duan, W., Li, Y., Jin, Z., Yan, J., Yu, S., & Yi, D. (2013) · Circulation · doi:10.1161/circulationaha.113.002480 · Cited by 87

Apoptosis-Modulating Drugs for Improved Cancer Therapy

Ocker, M., & Höpfner, M. (2012) · European Surgical Research · doi:10.1159/000336875 · Cited by 87

Complex regulation of autophagy in cancer – Integrated approaches to discover the networks that hold a double-edged sword

Kubisch, J., Türei, D., Földvári-Nagy, L., Dunai, Z. A., Zsákai, L., Varga, M., Vellai, T., Csermely, P., & Korcsmáros, T. (2013) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2013.06.009 · Cited by 87

Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

Kuramoto, K., Liang, H., Hong, J., & He, C. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.01.011 · Cited by 87

Autophagy in airway diseases: a new frontier in human asthma?

Zeki, A. A., Yeganeh, B., Kenyon, N. J., Post, M., & Ghavami, S. (2015) · Allergy · doi:10.1111/all.12761 · Cited by 87

Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

Liu, X.-D., Yao, J., Tripathi, D. N., Ding, Z., Xu, Y., Sun, M., Zhang, J., Bai, S., Germán, P., Hoang, A. G., et al. (2014) · Oncogene · doi:10.1038/onc.2014.199 · Cited by 87

Characteristics and requirements of basal autophagy in HEK 293 cells

Musiwaro, P., Smith, M. D., Manifava, M., Walker, S. A., & Ktistakis, N. T. (2013) · Autophagy · doi:10.4161/auto.25455 · Cited by 87

Sirtuin1 and autophagy protect cells from fluoride-induced cell stress

Suzuki, M., & Bartlett, J. D. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.11.023 · Cited by 87

Suppression of Autophagy by FIP200 Deletion Impairs DNA Damage Repair and Increases Cell Death upon Treatments with Anticancer Agents

Bae, H. R., & Guan, J. (2011) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-11-0098 · Cited by 87

Metabolic Dependencies in Pancreatic Cancer

Gohar, A. V., Zarei, M., Brody, J. R., & Winter, J. M. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00617 · Cited by 87

Curcumin and resveratrol suppress dextran sulfate sodium‑induced colitis in mice

Zhang, L., Xue, H., Zhao, G., Qiao, C., Sun, X., Pang, C., & Zhang, D. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.9974 · Cited by 87

IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes

Gupta, M., Shin, D.-M., Ramakrishna, L., Goussetis, D. J., Platanias, L. C., Xiong, H., Morse, H. C., & Ozato, K. (2015) · Nature Communications · doi:10.1038/ncomms7379 · Cited by 86

Mitochondrial dynamics, cell death and the pathogenesis of Parkinson’s disease

Büeler, H. (2010) · APOPTOSIS · doi:10.1007/s10495-010-0465-0 · Cited by 87

Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death

Meßner, B., Frotschnig, S., Steinacher-Nigisch, A., Winter, B., Eichmair, E., Gebetsberger, J., Schwaiger, S., Ploner, C., Laufer, G., & Bernhard, D. (2012) · Cell Death and Disease · doi:10.1038/cddis.2012.162 · Cited by 86

Autophagy Impairment in a Mouse Model of Neuropathic Pain

Berliocchi, L., Russo, R., Maiarù, M., Levato, A., Bagetta, G., & Corasaniti, M. T. (2011) · Molecular Pain · doi:10.1186/1744-8069-7-83 · Cited by 86

Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells

Chen, Z., Cao, J., Zhou, J.-S., Liu, H., Che, L., Mizumura, K., Li, W., Choi, A. M. K., & Shen, H. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00268.2013 · Cited by 86

Oxidative stress induces dysregulated autophagy in corneal epithelium of keratoconus patients

Shetty, R., Sharma, A., Pahuja, N. K., Chevour, P., Padmajan, N., Dhamodaran, K., Jayadev, C., Nuijts, R. M. M. A., Ghosh, A., & Jeyabalan, N. (2017) · PLoS ONE · doi:10.1371/journal.pone.0184628 · Cited by 86

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

Bilanges, B., Alliouachene, S., Pearce, W. P., Morelli, D., Szabadkai, G., Chung, Y.-L., Chicanne, G., Valet, C., Hill, J. M., Voshol, P. J., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01969-4 · Cited by 86

The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy

Pei, G., Buijze, H., Liu, H., Moura‐Alves, P., Goosmann, C., Brinkmann, V., Kawabe, H., Dorhoi, A., & Kaufmann, S. H. E. (2017) · Autophagy · doi:10.1080/15548627.2017.1376160 · Cited by 86

Chiral polymer modified nanoparticles selectively induce autophagy of cancer cells for tumor ablation

Yuan, L., Zhang, F., Qi, X., Yang, Y., Yan, C., Jiang, J., & Deng, J. (2018) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0383-9 · Cited by 87

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: Functional analysis of p62 and autophagy in hypoxic neuronal cells

Tanabe, F., Yone, K., Kawabata, N., Sakakima, H., Matsuda, F., Ishidou, Y., Maeda, S., Abematsu, M., Komiya, S., & Setoguchi, T. (2011) · Autophagy · doi:10.4161/auto.7.12.17892 · Cited by 85

Involvement of Autophagy in Coronavirus Replication

Maier, H. J., & Britton, P. (2012) · Viruses · doi:10.3390/v4123440 · Cited by 85

Metabolism as master of hematopoietic stem cell fate

Ito, K., Bonora, M., & Ito, K. (2018) · International Journal of Hematology · doi:10.1007/s12185-018-2534-z · Cited by 85

The small GTP ase MoYpt 7 is required for membrane fusion in autophagy and pathogenicity of M agnaporthe oryzae

Liu, X., Chen, S., Gao, H., Ning, G., Shi, H., Wang, Y., Dong, B., Qi, Y., Zhang, D., Lu, G., et al. (2015) · Environmental Microbiology · doi:10.1111/1462-2920.12903 · Cited by 85

Autophagy, signaling and obesity

Lavallard, V., Meijer, A. J., Codogno, P., & Gual, P. (2012) · Pharmacological Research · doi:10.1016/j.phrs.2012.09.003 · Cited by 85

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases

Li, B., Hu, Q., Wang, H., Man, N., Ren, H., Wen, L., Nukina, N., Fei, E., & Wang, G. (2010) · Cell Death and Differentiation · doi:10.1038/cdd.2010.55 · Cited by 85

Keeping bugs in check: The mucus layer as a critical component in maintaining intestinal homeostasis

Faderl, M., Noti, M., Corazza, N., & Mueller, C. (2015) · IUBMB Life · doi:10.1002/iub.1374 · Cited by 85

Involvement of autophagy in ovarian cancer: a working hypothesis

Peracchio, C., Alabiso, O., Valente, G., & Isidoro, C. (2012) · Journal of Ovarian Research · doi:10.1186/1757-2215-5-22 · Cited by 85

Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy

Zhao, Y., Guo, Q., Zhao, K., Zhou, Y., Li, W., Pan, C., Qiang, L., Li, Z., & Lu, N. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1375640 · Cited by 85

cPKCγ-Modulated Autophagy in Neurons Alleviates Ischemic Injury in Brain of Mice with Ischemic Stroke Through Akt-mTOR Pathway

Wei, H., Li, Y., Han, S., Liu, S., Zhang, N., Zhao, L., Li, S., & Li, J. (2016) · Translational Stroke Research · doi:10.1007/s12975-016-0484-4 · Cited by 84

Targeting Reactive Oxygen Species in Cancer via Chinese Herbal Medicine

Qian, Q., Chen, W., Cao, Y., Cao, Q., Cui, Y., Li, Y., & Wu, J. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/9240426 · Cited by 84

CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis

An, H., Chung, K. M., Park, H., Hong, J., Gim, J.-E., Choi, H., Lee, Y. W., Choi, J., Mun, J. Y., & Yu, S. (2019) · Autophagy · doi:10.1080/15548627.2019.1695398 · Cited by 84

Hexavalent chromium induces renal apoptosis and autophagy via disordering the balance of mitochondrial dynamics in rats

Zheng, X., Li, S., Li, J., Lv, Y., Wang, X., Wu, P., Yang, Q., Tang, Y., Liu, Y., & Zhang, Z. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111061 · Cited by 84

Amino Acid Homeostasis in Mammalian Cells with a Focus on Amino Acid Transport

Bröer, S., & Gauthier-Coles, G. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab342 · Cited by 86

Autophagy in term normal human placentas

Signorelli, P., Avagliano, L., Virgili, E., Gagliostro, V., Doi, P., Braidotti, P., Bulfamante, G., Ghidoni, R., & Marconi, A. M. (2011) · Placenta · doi:10.1016/j.placenta.2011.03.005 · Cited by 84

Autophagy in breast cancer and its implications for therapy.

Jain, K., Paranandi, K. S., Sridharan, S., & Basu, A. (2013) · PubMed Central · Cited by 84

Arabidopsis SINAT Proteins Control Autophagy by Mediating Ubiquitylation and Degradation of ATG13

Qi, H., Li, J., Xia, F., Chen, J., Xue, L., Han, M.-Q., Xie, L., Zhou, Q., & Xiao, S. (2019) · The Plant Cell · doi:10.1105/tpc.19.00413 · Cited by 83

Betulin Inhibits Lung Metastasis by Inducing Cell Cycle Arrest, Autophagy, and Apoptosis of Metastatic Colorectal Cancer Cells

Han, Y., Mun, J., Jeon, H. D., Kee, J., & Hong, S. (2019) · Nutrients · doi:10.3390/nu12010066 · Cited by 83

Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons

Moruno-Manchon, J. F., Lejault, P., Wang, Y., McCauley, B. S., Honarpisheh, P., Morales‐Scheihing, D., Singh, S. S., Dang, W., Kim, N., Urayama, A., et al. (2020) · eLife · doi:10.7554/elife.52283 · Cited by 84

Reactive Oxygen Species: A Double-Edged Sword in the Modulation of Cancer Signaling Pathway Dynamics

Nigam, M., Punia, B., Dimri, D. B., Mishra, A. P., Radu, A.-F., & Bungau, G. S. (2025) · Cells · doi:10.3390/cells14151207 · Cited by 83

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

Dunlop, E. A., Seifan, S., Claessens, T., Behrends, C., Kamps, M. A. F., Rozycka, E., Kemp, A. J., Nookala, R. K., Blenis, J., Coull, B. J., et al. (2014) · Autophagy · doi:10.4161/auto.29640 · Cited by 83

Porcine Circovirus Type 2 Induces Autophagy via the AMPK/ERK/TSC2/mTOR Signaling Pathway in PK-15 Cells

Zhu, B., Zhou, Y., Xu, F., Shuai, J., Li, X., & Fang, W. (2012) · Journal of Virology · doi:10.1128/jvi.01434-12 · Cited by 83

Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating autophagy

Liu, H., Gu, L., Tu, Y., Hu, H., Huang, Y., & Sun, W. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2015.114 · Cited by 83

Muscle Stem Cells and Aging

Hwang, A. B., & Brack, A. S. (2017) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2017.08.008 · Cited by 83

Emergent Properties of Proteostasis in Managing Cystic FibrosisPreprint

Balch, W. E., Roth, D. M., & Hutt, D. M. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004499 · Cited by 83

zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function

Herzog, C., Yang, C., Holmes, A., & Kaushal, G. P. (2012) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00659.2011 · Cited by 82

Interaction of autophagy with microRNAs and their potential therapeutic implications in human cancers

Zhao, J., Han, W., Sui, X., Xie, J., & Pan, H. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.09.039 · Cited by 82

Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment

Mehrzadi, S., Hemati, K., Reiter, R. J., & Hosseinzadeh, A. (2020) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2020.1737015 · Cited by 82

Apigetrin induces extrinsic apoptosis, autophagy and G2/M phase cell cycle arrest through PI3K/AKT/mTOR pathway in AGS human gastric cancer cell

Kim, S. M., Vetrivel, P., Ha, S. E., Kim, H. H., Kim, J., & Kim, G. S. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108427 · Cited by 82

A Message from the Human Placenta: Structural and Immunomodulatory Defense against SARS-CoV-2

Kreis, N., Ritter, A., Louwen, F., & Yuan, J. (2020) · Cells · doi:10.3390/cells9081777 · Cited by 83

The perplexing role of autophagy in plant innate immune responses

Zhou, J., Yu, J., & Chen, Z. (2014) · Molecular Plant Pathology · doi:10.1111/mpp.12118 · Cited by 82

cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1

Ugland, H. G., Naderi, S., Brech, A., Collas, P., & Blomhoff, H. K. (2011) · Autophagy · doi:10.4161/auto.7.10.16649 · Cited by 82

DJ-1, a cancer and Parkinson’s disease associated protein, regulates autophagy through JNK pathway in cancer cells

Ren, H., Fu, K., Mu, C., Li, B., Wang, D., & Wang, G. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.05.001 · Cited by 82

The Role of Autophagy for the Regeneration of the Aging Liver

Xu, F., Hua, C., Tautenhahn, H., Dirsch, O., & Dahmen, U. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103606 · Cited by 81

Impaired autophagy: The collateral damage of lysosomal storage disorders

Myerowitz, R., Puertollano, R., & Raben, N. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.103166 · Cited by 81

The role of autophagy in bone homeostasis

Guo, Y., Su, T., Yang, M., Li, C., Guo, Q., Xiao, Y., Huang, Y., Liu, Y., & Luo, X. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30111 · Cited by 81

The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy

Sheridan, M., & Öğretmen, B. (2021) · Cancers · doi:10.3390/cancers13102475 · Cited by 82

PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells

Navaei, Z. N., Khalili‐Tanha, G., Zangouei, A. S., Abbaszadegan, M. R., & Moghbeli, M. (2021) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.32604/or.2022.025323 · Cited by 81

Yeast vacuoles: more than a model lysosome

Armstrong, J. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.06.010 · Cited by 81

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

Ambjørn, M., Ejlerskov, P., Liu, Y., Lees, M. J., Jäättelä, M., & Issazadeh‐Navikas, S. (2012) · Autophagy · doi:10.4161/auto.22831 · Cited by 81

Palmitic acid induces autophagy in hepatocytes via JNK2 activation

Tu, Q., Zheng, R., Li, J., Hu, L., Chang, Y., Li, L., Li, M., Wang, R., Huang, D., Wu, M., et al. (2014) · Acta Pharmacologica Sinica · doi:10.1038/aps.2013.170 · Cited by 81

The Evolving, Multifaceted Roles of Autophagy in Cancer

Liu, J., & Debnath, J. (2016) · Advances in cancer research · doi:10.1016/bs.acr.2016.01.005 · Cited by 82

Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice

Yang, H., Ni, H., Guo, F., Ding, Y., Shi, Y., Lahiri, P., Fröhlich, L. F., Rülicke, T., Smole, C., Schmidt, V. C., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.739821 · Cited by 81

Apple autophagy-related protein MdATG3s afford tolerance to multiple abiotic stresses

Wang, P., Sun, X., Jia, X., & Ma, F. (2016) · Plant Science · doi:10.1016/j.plantsci.2016.12.003 · Cited by 81

Autophagy and acetaminophen-induced hepatotoxicity

Shan, S., Shen, Z., & Song, F. (2018) · Archives of Toxicology · doi:10.1007/s00204-018-2237-5 · Cited by 81

Contrasting and emerging roles of autophagy in plant immunity

Leary, A. Y., Savage, Z., Tümtaş, Y., & Bozkurt, T. O. (2019) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2019.07.002 · Cited by 81

Resilience of death: intrinsic disorder in proteins involved in the programmed cell death

Peng, Z., Xue, B., Kurgan, L., & Uversky, V. N. (2013) · Cell Death and Differentiation · doi:10.1038/cdd.2013.65 · Cited by 80

Mitochondrial quality control in AMD: does mitophagy play a pivotal role?

Hyttinen, J. M. T., Viiri, J., Kaarniranta, K., & Błasiak, J. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2843-7 · Cited by 82

Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

Leong, Y. Q., Ng, K. Y., Chye, S. M., Ling, A. P. K., & Koh, R. Y. (2019) · Metabolic Brain Disease · doi:10.1007/s11011-019-00516-y · Cited by 80

Autophagy in the cancer-immunity dialogue

Yamazaki, T., Pedro, J. M. B., Galluzzi, L., Kroemer, G., & Pietrocola, F. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.12.003 · Cited by 80

An updated review of autophagy in ischemic stroke: From mechanisms to therapies

Wang, X., Fang, Y., Huang, Q., Xu, P., Lenahan, C., Lü, J., Zheng, J., Dong, X., Shao, A., & Zhang, J. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113684 · Cited by 80

Inducing autophagy

Harder, L. M., Bunkenborg, J., & Andersen, J. (2013) · Autophagy · doi:10.4161/auto.26863 · Cited by 80

Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy

Gagliostro, V., Casas, J., Caretti, A., Abad, J. L., Tagliavacca, L., Ghidoni, R., Fabriàs, G., & Signorelli, P. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.08.025 · Cited by 80

Pro-autophagic signal induction by bacterial pore-forming toxins

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The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

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