Regulation Mechanisms and Signaling Pathways of Autophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

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p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

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Autophagy as a Regulated Pathway of Cellular Degradation

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

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MicroRNA 17-5p regulates autophagy inMycobacterium tuberculosis-infected macrophages by targeting Mcl-1 and STAT3

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DJ-1 as a human oncogene and potential therapeutic target

Cao, J., Lou, S., Ying, M., & Yang, B. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.11.012 · Cited by 117

Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells

Basu, S., Rajakaruna, S., Reyes, B. A. S., Bockstaele, E. V., & Menko, A. S. (2014) · Autophagy · doi:10.4161/auto.28768 · Cited by 117

Autophagy inhibition of hsa-miR-19a-3p/19b-3p by targeting TGF-β R II during TGF-β1-induced fibrogenesis in human cardiac fibroblasts

Zou, M., Wang, F., Gao, R., Wu, J., Ou, Y., Chen, X., Wang, T., Zhou, X. Y., Zhu, W., Li, P., et al. (2016) · Scientific Reports · doi:10.1038/srep24747 · Cited by 117

Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype

Sallman, D. A., Cluzeau, T., Basiorka, A. A., & List, A. F. (2016) · Frontiers in Oncology · doi:10.3389/fonc.2016.00151 · Cited by 117

Autophagy-related approaches for improving nutrient use efficiency and crop yield protection

Avin‐Wittenberg, T., Baluška, F., Bozhkov, P. V., Elander, P. H., Fernie, A. R., Galili, G., Hassan, A., Hofius, D., Isono, E., Bars, R. L., et al. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/ery069 · Cited by 117

Cardiovascular protection by SGLT2 inhibitors – Do anti-inflammatory mechanisms play a role?

Elrakaybi, A., Laubner, K., Zhou, Q., Hug, M. J., & Seufert, J. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101549 · Cited by 118

Astrocyte elevated gene-1 induces protective autophagy

Bhutia, S. K., Kegelman, T. P., Das, S. K., Azab, B., Su, Z.-Z., Lee, S., Sarkar, D., & Fisher, P. B. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009479107 · Cited by 117

The yeast autophagy protease Atg4 is regulated by thioredoxin

Pérez‐Pérez, M. E., Zaffagnini, M., Marchand, C. H., Crespo, J. L., & Lemaire, S. D. (2014) · Autophagy · doi:10.4161/auto.34396 · Cited by 117

A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells

Milan, E., Perini, T., Resnati, M., Orfanelli, U., Oliva, L., Raimondi, A., Cascio, P., Bachi, A., Marcatti, M., Ciceri, F., et al. (2015) · Autophagy · doi:10.1080/15548627.2015.1052928 · Cited by 116

Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

Servin, A. L. (2014) · Clinical Microbiology Reviews · doi:10.1128/cmr.00036-14 · Cited by 116

The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis

Fortini, P., Ferretti, C., Iorio, E., Cagnin, M., Garribba, L., Pietraforte, D., Falchi, M., Pascucci, B., Baccarini, S., Morani, F., et al. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.50 · Cited by 116

Mitochondria-Associated Membranes and ER Stress

van Vliet, A. R., & Agostinis, P. (2017) · Current topics in microbiology and immunology · doi:10.1007/82_2017_2 · Cited by 116

PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses

Tsubouchi, K., Araya, J., & Kuwano, K. (2018) · Inflammation and Regeneration · doi:10.1186/s41232-018-0077-6 · Cited by 117

Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice

Brown, J. L., Lee, D. E., Rosa‐Caldwell, M. E., Brown, L. A., Perry, R. A., Haynie, W. S., Huseman, K., Sataranatarajan, K., Remmen, H. V., Washington, T. A., et al. (2018) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12354 · Cited by 117

Specificity of 3D MSC Spheroids Microenvironment: Impact on MSC Behavior and Properties

Jauković, A., Abadjieva, D. V., Trivanović, D. I., Stoyanova, E., Kostadinova, M., Pashova, S., Kestendjieva, S., Кукољ, Т., Ješeta, M., Kistanova, E. K., et al. (2020) · Stem Cell Reviews and Reports · doi:10.1007/s12015-020-10006-9 · Cited by 116

Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination

Xu, C., Feng, K., Zhao, X., Huang, S., Cheng, Y., Liu, Q., Wang, Y., Sun, H., Jin, M., Chuang, T., et al. (2014) · Autophagy · doi:10.4161/15548627.2014.981792 · Cited by 116

Autophagy, an important therapeutic target for pulmonary fibrosis diseases

Zhao, H., Wang, Y., Qiu, T., Liu, W., & Yao, P. (2020) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.12.016 · Cited by 115

This old heart: Cardiac aging and autophagy

Linton, P., Gurney, M. A., Sengstock, D. M., Mentzer, R. M., & Gottlieb, R. A. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.12.017 · Cited by 115

Immunity to viruses

Braciale, T. J., & Hahn, Y. S. (2013) · Immunological Reviews · doi:10.1111/imr.12109 · Cited by 115

The Placenta as a Barrier to Viral Infections

Delorme‐Axford, E., Sadovsky, Y., & Coyne, C. B. (2014) · Annual Review of Virology · doi:10.1146/annurev-virology-031413-085524 · Cited by 115

Converging Pathways in the Occurrence of Endoplasmic Reticulum (ER) Stress in Huntingtons Disease

Vidal, R. L., Caballero, B., Couve, A., & Hetz, C. A. (2011) · Current Molecular Medicine · doi:10.2174/156652411794474419 · Cited by 115

Modulation of Autophagy by Sorafenib: Effects on Treatment Response

Prieto‐Domínguez, N., Ordóñez, R., Fernández, A., Palomo, A. G., Muntané, J., González‐Gallego, J., & Mauriz, J. L. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00151 · Cited by 115

Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria

Krakauer, T. (2019) · Mediators of Inflammation · doi:10.1155/2019/2471215 · Cited by 115

Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection

Kuang, E., Okumura, C. Y. M., Sheffy-Levin, S., Varsano, T., Shu, V. C.-W., Qi, J., Niesman, I. R., Yang, H., López-Otı́n, C., Yang, W. Y., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003007 · Cited by 115

Untitled work

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Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers

Nogalska, A., D'Agostino, C., Terracciano, C., Engel, W. K., & Askanas, V. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.100050 · Cited by 114

Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation

Martínez‐Vicente, M. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.03.005 · Cited by 114

Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint

Zheng, K., Li, Y., Wang, S., Wang, X., Liao, C., Hu, X., Fan, L., Kang, Q., Zeng, Y., Wu, X., et al. (2016) · Autophagy · doi:10.1080/15548627.2016.1192751 · Cited by 114

The Interrelation between Reactive Oxygen Species and Autophagy in Neurological Disorders

Fang, C., Gu, L., Smerin, D., Mao, S., & Xiong, X. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/8495160 · Cited by 114

Aspirin Recapitulates Features of Caloric Restriction

Pietrocola, F., Castoldi, F., Markaki, M., Lachkar, S., Chen, G., Enot, D. P., Durand, S., Bossut, N., Tong, M., Malik, S. A., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.02.024 · Cited by 114

Acquired resistance to aromatase inhibitors: where we stand!

Augusto, T. V., Correia‐da‐Silva, G., Rodrigues, C., Teixeira, N. A. A., & Amaral, C. (2018) · Endocrine Related Cancer · doi:10.1530/erc-17-0425 · Cited by 114

Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism

Cheng, X., Ma, X., Zhu, Q., Song, D., Ding, X., Li, L., Jiang, X. M., Wang, X., Tian, R. L., Su, H., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2018.12.017 · Cited by 115

Autophagy: A Crucial Moderator of Redox Balance, Inflammation, and Apoptosis in Lung Disease

Nakahira, K., Cloonan, S. M., Mizumura, K., Choi, A. M. K., & Ryter, S. W. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5373 · Cited by 115

Therapeutic Effects of Rapamycin on MPTP-Induced Parkinsonism in Mice

Liu, K., Shi, N., Sun, Y., Zhang, T., & Sun, X. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0909-8 · Cited by 114

Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors

Kanai, R., Zaupa, C., Sgubin, D., Antoszczyk, S. J., Martuza, R. L., Wakimoto, H., & Rabkin, S. D. (2012) · Journal of Virology · doi:10.1128/jvi.00017-12 · Cited by 114

Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

Walters, H. E., Deneka-Hannemann, S., & Cox, L. S. (2016) · Aging · doi:10.18632/aging.100872 · Cited by 113

Modeling general proteostasis: proteome balance in health and disease

Roth, D., & Balch, W. E. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.11.001 · Cited by 113

The Role of Autophagy During Development in Higher Eukaryotes

Bartolomeo, S. D., Nazio, F., & Cecconi, F. (2010) · Traffic · doi:10.1111/j.1600-0854.2010.01103.x · Cited by 113

The roles of reactive oxygen species (ROS) and autophagy in the survival and death of leukemia cells

Chen, Y., Liu, H., Luo, X.-J., Zhao, Z., Zou, Z., Li, J., Lin, X., & Liang, Y. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.02.004 · Cited by 113

Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives

Sun, X., Yan, P., Zou, C., Wong, Y., Shu, Y., Lee, Y. M., Zhang, C., Yang, N., Wang, J., & Zhang, J. (2019) · Medicinal Research Reviews · doi:10.1002/med.21580 · Cited by 113

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

Mariño, G., Pietrocola, F., Madeo, F., & Kroemer, G. (2014) · Autophagy · doi:10.4161/auto.36413 · Cited by 112

New Insight into the Mechanism and Function of Autophagy in Plant Cells

Yang, X., & Bassham, D. C. (2015) · International review of cytology · doi:10.1016/bs.ircmb.2015.07.005 · Cited by 112

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish

Huang, G., Zhang, F., Ye, Q., & Wang, H. (2016) · Autophagy · doi:10.1080/15548627.2016.1183843 · Cited by 112

Proteotoxicity and Cardiac Dysfunction

McLendon, P. M., & Robbins, J. M. (2015) · Circulation Research · doi:10.1161/circresaha.116.305372 · Cited by 111

MiR-214 increases the sensitivity of breast cancer cells to tamoxifen and fulvestrant through inhibition of autophagy

Yu, X., Luo, A., Liu, Y., Wang, S., Li, Y., Shi, W., Liu, Z., & Qu, X. (2015) · Molecular Cancer · doi:10.1186/s12943-015-0480-4 · Cited by 111

Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling

Choi, H., Merceron, C., Mangiavini, L., Seifert, E. L., Schipani, E., Shapiro, I. M., & Risbud, M. V. (2016) · Autophagy · doi:10.1080/15548627.2016.1192753 · Cited by 111

Differential processing of Arabidopsis ubiquitin-like Atg8 autophagy proteins by Atg4 cysteine proteases

Woo, J., Park, E., & Dinesh‐Kumar, S. P. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1318207111 · Cited by 111

Autophagy takes flight in Drosophila

Chang, Y.-Y., & Neufeld, T. P. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.006 · Cited by 110

mTOR inhibitors and their clinical application in cervical, endometrial and ovarian cancers: A critical review

Husseinzadeh, N., & Husseinzadeh, H. D. (2014) · Gynecologic Oncology · doi:10.1016/j.ygyno.2014.02.017 · Cited by 110

Induction of Autophagy and Apoptosis via PI3K/AKT/TOR Pathways by Azadirachtin A in Spodoptera litura Cells

Shao, X., Lai, D., Zhang, L., & Xu, H. (2016) · Scientific Reports · doi:10.1038/srep35482 · Cited by 110

Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma

Roy, M., Liang, L., Xiao, X., Peng, Y., Luo, Y., Zhou, W., Zhang, J., Qiu, L., Zhang, S., Liu, F., et al. (2016) · Theranostics · doi:10.7150/thno.15584 · Cited by 110

Ubiquitin-Dependent Lysosomal Membrane Protein Sorting and Degradation

Li, M., Rong, Y., Chuang, Y.-S., Peng, D., & Emr, S. D. (2015) · Molecular Cell · doi:10.1016/j.molcel.2014.12.012 · Cited by 110

Omega-3 Polyunsaturated Fatty Acids and Cancer

Jing, K., Wu, T., & Lim, K. (2013) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/18715206113139990319 · Cited by 110

Autophagy as an emerging target in cardiorenal metabolic disease: From pathophysiology to management

Zhang, Y., Whaley‐Connell, A. T., Sowers, J. R., & Ren, J. T. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.06.004 · Cited by 109

Natural compounds modulate the autophagy with potential implication of stroke

Ahsan, A., Liu, M., Zheng, Y., Yan, W., Pan, L., Li, Y., Ma, S., Zhang, X., Cao, M., Wu, Z., et al. (2020) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2020.10.018 · Cited by 109

Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy

Shen, T., Cai, L.-D., Liu, Y., Li, S., Gan, W.-J., Li, X., Wang, J., Guo, P.-D., Zhou, Q. Y., Lu, X.-X., et al. (2018) · Journal of Hematology & Oncology · doi:10.1186/s13045-018-0638-9 · Cited by 109

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells

Zhou, J., Hu, S.-E., Tan, S.-H., Cao, R., Chen, Y., Xia, D., Zhu, X., Yang, X., Ong, C. N., & Shen, H. (2012) · Autophagy · doi:10.4161/auto.18721 · Cited by 108

AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability

Jonas, M. C., Pehar, M., & Puglielli, L. (2010) · Journal of Cell Science · doi:10.1242/jcs.068841 · Cited by 108

Autophagy is required and protects against apoptosis during myoblast differentiation

McMillan, E. M., & Quadrilatero, J. (2014) · Biochemical Journal · doi:10.1042/bj20140312 · Cited by 108

Metabolic effects of fasting on human and mouse blood in vivo

Pietrocola, F., Demont, Y., Castoldi, F., Enot, D. P., Durand, S., Semeraro, M., Baracco, E. E., Pol, J. G., Pedro, J. M. B., Bordenave, C., et al. (2017) · Autophagy · doi:10.1080/15548627.2016.1271513 · Cited by 107

C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy

Salcher, S., Hermann, M., Kiechl‐Kohlendorfer, U., Ausserlechner, M. J., & Obexer, P. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0661-4 · Cited by 107

Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease

Khambu, B., Yan, S., Huda, N., Liu, G., & Yin, X. (2018) · Liver Research · doi:10.1016/j.livres.2018.09.004 · Cited by 107

Endometrial TGF-β, IL-10, IL-17 and autophagy are dysregulated in women with recurrent implantation failure with chronic endometritis

Wang, W., Zhang, H., Chen, Z.-Q., Zhang, W., Liu, X., Fang, J.-Y., Liu, F., & Kwak-Kim, J. Y.-H. (2019) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-018-0444-9 · Cited by 107

Stress-induced cleavage of Myc promotes cancer cell survivalPreprint

Conacci‐Sorrell, M., Ngouenet, C., Anderson, S., Brabletz, T., & Eisenman, R. N. (2014) · Genes & Development · doi:10.1101/gad.231894.113 · Cited by 107

Far-Red-Absorbing Cationic Phthalocyanine Photosensitizers: Synthesis and Evaluation of the Photodynamic Anticancer Activity and the Mode of Cell Death Induction

Macháček, M., Cidlina, A., Novakova, V., Svec, J., Rudolf, E., Miletín, M., Kučera, R., Šimůnek, T., & Zimčík, P. (2015) · Journal of Medicinal Chemistry · doi:10.1021/jm5014852 · Cited by 106

Neferine isolated from Nelumbo nucifera enhances anti-cancer activities in Hep3B cells: Molecular mechanisms of cell cycle arrest, ER stress induced apoptosis and anti-angiogenic response

Yoon, J., Kim, H.-M., Yadunandam, A. K., Kim, N., Jung, H., Choi, J., Kim, C.-Y., & Kim, G. (2013) · Phytomedicine · doi:10.1016/j.phymed.2013.03.024 · Cited by 106

High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy

Gonzalez-Malerva, L. G., Park, J.-H., Zou, L., Hu, Y., Moradpour, Z., Pearlberg, J., Sawyer, J., Stevens, H., Harlow, E., & LaBaer, J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018157108 · Cited by 106

Quinacrine-Mediated Autophagy and Apoptosis in Colon Cancer Cells Is Through a p53- and p21-Dependent Mechanism

Mohapatra, P., Preet, R., Das, D., Satapathy, S. R., Choudhuri, T., Wyatt, M. D., & Kundu, C. N. (2012) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504012x13473664562628 · Cited by 106

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

Richter‐Landsberg, C., & Leyk, J. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1158-x · Cited by 106

Autophagy in Cancer Therapy

Fulda, S. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00128 · Cited by 106

Autophagy in Adipose Tissue Physiology and Pathophysiology

Ferhat, M., Funai, K., & Boudina, S. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7626 · Cited by 106

Natural Compounds and Autophagy: Allies Against Neurodegeneration

Stacchiotti, A., & Corsetti, G. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.555409 · Cited by 106

Circadian autophagy rhythm: a link between clock and metabolism?

Ma, D., Li, S., Molusky, M. M., & Lin, J. D. (2012) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2012.03.004 · Cited by 106

p53-mediated autophagic regulation: A prospective strategy for cancer therapy

Tang, J., Di, J., Cao, H., Bai, J., & Zheng, J. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.04.014 · Cited by 105

Regulation of membrane biogenesis in autophagy via PI3P dynamics

Noda, T., Matsunaga, K., Taguchi‐Atarashi, N., & Yoshimori, T. (2010) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2010.04.002 · Cited by 105

Statins, autophagy and cancer metastasis

Zhang, J., Yang, Z., Xie, L., Xu, L., Xu, D., & Liu, X. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.11.001 · Cited by 105

NUPR1 maintains autolysosomal efflux by activatingSNAP25transcription in cancer cells

Mu, Y., Yan, X., Li, D., Zhao, D., Wang, L., Wang, X., Gao, D., Yang, J., Zhang, H., Li, Y., et al. (2017) · Autophagy · doi:10.1080/15548627.2017.1338556 · Cited by 105

The physiological roles of autophagy in the mammalian life cycle

Wang, L., Ye, X., & Zhao, T. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12464 · Cited by 105

δ‐Tocotrienol induces apoptosis, involving endoplasmic reticulum stress and autophagy, and paraptosis in prostate cancer cells

Fontana, F., Moretti, R. M., Raimondi, M., Marzagalli, M., Beretta, G., Procacci, P., Sartori, P., Marelli, M. M., & Limonta, P. (2019) · Cell Proliferation · doi:10.1111/cpr.12576 · Cited by 105

ER stress modulates cellular metabolism

Wang, X., Eno, C. O., Altman, B. J., Zhu, Y., Zhao, G., Olberding, K. E., Rathmell, J. C., & Li, C. (2011) · Biochemical Journal · doi:10.1042/bj20101864 · Cited by 105

Autophagy is activated to protect against endotoxic acute kidney injury

Mei, S., Livingston, M., Hao, J., li, L., Mei, C., & Dong, Z. (2016) · Scientific Reports · doi:10.1038/srep22171 · Cited by 104

Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR

Wang, Y., Huang, Y., Hobbs, H. H., & Cohen, J. C. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m028563 · Cited by 104

Autophagic flux is required for the synthesis of triacylglycerols and ribosomal protein turnover in Chlamydomonas

Couso, I., Pérez‐Pérez, M. E., Martínez‐Force, E., Kim, H.-S., He, Y., Umen, J., & Crespo, J. L. (2017) · Journal of Experimental Botany · doi:10.1093/jxb/erx372 · Cited by 104

NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter

Lee, D.-E., Yoo, J. E., Kim, J., Kim, S., Kim, S., Lee, H., & Cheong, H. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2242-5 · Cited by 104

The role of lipotoxicity in kidney disease: From molecular mechanisms to therapeutic prospects

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