Regulation Mechanisms and Signaling Pathways of Autophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Kominami, E., Ohsumi, Y., & Yoshimori, T. (2000) · The EMBO Journal · doi:10.1093/emboj/19.21.5720 · Cited by 6,605

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J.-A., Outzen, H., Øvervatn, A., Bjørkøy, G., & Johansen, T. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702824200 · Cited by 4,578

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914

Autophagy as a Regulated Pathway of Cellular Degradation

Klionsky, D. J., & Emr, S. D. (2000) · Science · doi:10.1126/science.290.5497.1717 · Cited by 3,630

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200507002 · Cited by 3,276

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082

Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy

Bravo-Santano, N., Ellis, J. K., Mateos, L. M., Calle, Y., Keun, H. C., Behrends, V., & Letek, M. (2018) · mSphere · doi:10.1128/msphere.00374-18 · Cited by 101

Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells

Xavier, C. P. R., Lima, C. F., Pedro, D. F. N., Wilson, J. M., Kristiansen, K., & Pereira‐Wilson, C. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.04.004 · Cited by 101

Autophagy-regulating small molecules and their therapeutic applications

Baek, K.-H., Park, J., & Shin, I. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15328a · Cited by 101

Autophagy in Neurodegenerative Diseases and Metal Neurotoxicity

Zhang, Z., Miah, M. R., Culbreth, M. E., & Aschner, M. (2016) · Neurochemical Research · doi:10.1007/s11064-016-1844-x · Cited by 101

Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement

Zhou, H., Feng, L., Xu, F., Sun, Y., Ma, Y., Zhang, X., Liu, H., Xu, G., Wu, X., Shen, Y., et al. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.03.003 · Cited by 101

Ontogeny and water temperature influences the antiviral response of the Pacific oyster, Crassostrea gigas

Green, T. J., Montagnani, C., Benkendorff, K., Robinson, N., & Speck, P. G. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.10.026 · Cited by 100

Autophagic pathways in Parkinson disease and related disorders

Xilouri, M., & Stefanis, L. (2011) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399411001803 · Cited by 100

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway

Gui, D., Cui, Z., Zhang, L., Chang, Y., Yao, D., Xu, M., Chen, M., Wu, P., Li, G., Wang, L., et al. (2017) · BMC Pulmonary Medicine · doi:10.1186/s12890-017-0477-4 · Cited by 100

The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia

Lai, M., Yao, H., Shah, S. Z. A., Wu, W., Wang, D., Zhao, Y., Wang, L., Zhou, X., Zhao, D., & Yang, L. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00116 · Cited by 100

Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells

Xu, Y., Zhang, Y., García‐Cañaveras, J. C., Guo, L., Kan, M., Yu, S., Blair, I. A., Rabinowitz, J. D., & Yang, X. (2020) · Science · doi:10.1126/science.abb4467 · Cited by 100

Cytoprotective effects of hesperetin and hesperidin against amyloid β‐induced impairment of glucose transport through downregulation of neuronal autophagy

Huang, S., Tsai, S.-Y., Lin, J., Wu, C., & Yen, G. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100682 · Cited by 100

New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation

Bamias, G., Corridoni, D., Pizarro, T. T., & Cominelli, F. (2012) · Cytokine · doi:10.1016/j.cyto.2012.06.014 · Cited by 100

FoxO, Autophagy, and Cardiac Remodeling

Ferdous, A., Battiprolu, P. K., Ni, Y. G., Rothermel, B. A., & Hill, J. A. (2010) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-010-9200-z · Cited by 100

RNF185, a Novel Mitochondrial Ubiquitin E3 Ligase, Regulates Autophagy through Interaction with BNIP1

Tang, F., Wang, B., Li, N., Wu, Y., Jia, J., Suo, T., Chen, Q., Liu, Y., & Tang, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024367 · Cited by 99

Beclin-1: a therapeutic target at the intersection of autophagy, immunotherapy, and cancer treatment

Cao, Z., Tian, K., Ran, Y., Zhou, H., Zhou, L., Ding, Y., & Tang, X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1506426 · Cited by 101

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Noguchi, M., Hirata, N., & Suizu, F. (2014) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2014.07.013 · Cited by 99

Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

Napolitano, G., Johnson, J. L., He, J. N., Rocca, C. J., Monfregola, J., Pestonjamasp, K. N., Cherqui, S., & Catz, S. D. (2015) · EMBO Molecular Medicine · doi:10.15252/emmm.201404223 · Cited by 99

Autophagy, apoptosis, and mitochondria: molecular integration and physiological relevance in skeletal muscle

Bloemberg, D., & Quadrilatero, J. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00261.2018 · Cited by 100

The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function

Montaseri, A., Giampietri, C., Rossi, M., Riccioli, A., Fattore, A. D., & Filippini, A. (2020) · Biomolecules · doi:10.3390/biom10101398 · Cited by 98

Resistance to Intervention: Paclitaxel in Breast Cancer

Dan, V. M., Raveendran, R. S., & Baby, S. (2020) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557520999201214234421 · Cited by 98

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

Kaza, N., Kohli, L., & Roth, K. A. (2011) · Brain Pathology · doi:10.1111/j.1750-3639.2011.00544.x · Cited by 98

Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll‐like receptor‐mediated autophagy

Xu, C., Liu, J., Hsu, L., Luo, Y., Xiang, R., & Chuang, T. (2011) · The FASEB Journal · doi:10.1096/fj.10-167676 · Cited by 98

Antiviral immunity in marine molluscs

Green, T. J., Raftos, D. A., Speck, P. G., & Montagnani, C. (2015) · Journal of General Virology · doi:10.1099/jgv.0.000244 · Cited by 98

Mycobacterial Induction of Autophagy Varies by Species and Occurs Independently of Mammalian Target of Rapamycin Inhibition

Zullo, A. J., & Lee, S. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.320135 · Cited by 97

Neurodegeneration with Brain Iron Accumulation: Genetic Diversity and Pathophysiological Mechanisms

Meyer, E., Kurian, M. A., & Hayflick, S. J. (2015) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090314-025011 · Cited by 97

Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

Zhao, C., Chen, Z., Qi, J., Duan, S., Huang, Z., Zhang, C., Wu, L., Zeng, M., Zhang, B., Wang, N., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.15470 · Cited by 97

Aging‐related Atg5 defect impairs neutrophil extracellular traps formation

Xu, F., Zhang, C., Zou, Z., Fan, E., Chen, L., Li, Y., Billiar, T. R., Wilson, M. A., Shi, X., & Fan, J. (2017) · Immunology · doi:10.1111/imm.12740 · Cited by 98

Molecular targets and anticancer potential of sanguinarine—a benzophenanthridine alkaloid

Galadari, S., Rahman, A. U., Pallichankandy, S., & Thayyullathil, F. (2017) · Phytomedicine · doi:10.1016/j.phymed.2017.08.006 · Cited by 97

CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation

Li, X., Wu, X.-Q., Deng, R., Li, D., Tang, J., Chen, W.-D., Chen, J.-H., Ji, J., Jiao, L., Jiang, S., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01272-2 · Cited by 97

Hematopoietic stem cell fate through metabolic control

Ito, K., & Ito, K. (2018) · Experimental Hematology · doi:10.1016/j.exphem.2018.05.005 · Cited by 98

The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review

Luo, P., Gao, F., Niu, D., Sun, X., Song, Q., Guo, C., Liang, Y., & Sun, W. (2019) · BioMed Research International · doi:10.1155/2019/5171602 · Cited by 97

Sirtuin function in aging heart and vessels

Cencioni, C., Spallotta, F., Mai, A., Martelli, F., Farsetti, A., Zeiher, A. M., & Gaetano, C. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.12.023 · Cited by 97

Genes and Environment: How Will Our Concepts on the Pathophysiology of IBD Develop in the Future?

Kaser, A., Zeißig, S., & Blumberg, R. S. (2010) · Digestive Diseases · doi:10.1159/000320393 · Cited by 97

IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway

Qin, B., Zhou, Z. L., He, J., Yan, C., & Ding, S. (2015) · Scientific Reports · doi:10.1038/srep15701 · Cited by 97

Apoptosis, autophagy & endoplasmic reticulum stress in diabetes mellitus

Demirtaş, L., Güçlü, A., Erdur, F. M., Akbaş, E. M., Özçiçek, A., Önk, D., & Türkmen, K. (2016) · The Indian Journal of Medical Research · doi:10.4103/0971-5916.200887 · Cited by 99

Regulation of epithelial-mesenchymal transition and metastasis by TGF-β, P-bodies, and autophagy

Hardy, S. D., Shinde, A. B., Wang, W., Wendt, M. K., & Geahlen, R. L. (2017) · Oncotarget · doi:10.18632/oncotarget.21871 · Cited by 96

The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos: a mechanistic study

Kang, M.-H., Das, J., Gurunathan, S., Park, H., Song, H., Park, C., & Kim, J. (2017) · Theranostics · doi:10.7150/thno.21662 · Cited by 96

Exosomal cargos modulate autophagy in recipient cells via different signaling pathways

Hassanpour, M., Rezabakhsh, A., Rezaie, J., Nouri, M., & Rahbarghazi‬, R. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00455-7 · Cited by 96

Autophagy in acute leukemias: A double-edged sword with important therapeutic implications

Evangelisti, C., Evangelisti, C., Chiarini, F., Lonetti, A., Buontempo, F., Neri, L. M., McCubrey, J. A., & Martelli, A. M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.09.023 · Cited by 96

Tumor suppressive functions of ceramide: evidence and mechanisms

Galadari, S., Rahman, A. U., Pallichankandy, S., & Thayyullathil, F. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1109-1 · Cited by 97

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

Patergnani, S., Marchi, S., Rimessi, A., Bonora, M., Giorgi, C., Mehta, K. D., & Pinton, P. (2013) · Autophagy · doi:10.4161/auto.25239 · Cited by 96

Removing Protein Aggregates: The Role of Proteolysis in Neurodegeneration

Nijholt, D. A. T., Kimpe, L. D., Elfrink, H. L., Hoozemans, J. J. M., & Scheper, W. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711795843236 · Cited by 96

IL-37 induces autophagy in hepatocellular carcinoma cells by inhibiting the PI3K/AKT/mTOR pathway

Li, T.-T., Zhu, D., Mou, T., Guo, Z., Pu, J., Chen, Q., Wei, X., & Wu, Z. (2017) · Molecular Immunology · doi:10.1016/j.molimm.2017.04.010 · Cited by 96

Inside the β Cell: Molecular Stress Response Pathways in Diabetes Pathogenesis

Kulkarni, A., Muralidharan, C., May, S. C., Tersey, S. A., & Mirmira, R. G. (2022) · Endocrinology · doi:10.1210/endocr/bqac184 · Cited by 95

Autophagy Protects against Oxaliplatin-Induced Cell Death via ER Stress and ROS in Caco-2 Cells

Shi, Y., Tang, B., Yu, P.-W., Tang, B., Hao, Y., Lei, X., Luo, H.-X., & Zeng, D.-Z. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051076 · Cited by 95

Herpes Simplex Virus γ34.5 Interferes with Autophagosome Maturation and Antigen Presentation in Dendritic Cells

Gobeil, P., & Leib, D. A. (2012) · mBio · doi:10.1128/mbio.00267-12 · Cited by 95

AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells

Lotsberg, M. L., Wnuk-Lipińska, K., Terry, S., Tan, T. Z., Lü, N., Trachsel-Moncho, L., Røsland, G. V., Siraji, M. I., Hellesøy, M., Rayford, A. J., et al. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.01.015 · Cited by 95

Crosstalk between exosomes and autophagy: A review of molecular mechanisms and therapies

Xing, H., Tan, J., Miao, Y., Lv, Y., & Zhang, Q. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16276 · Cited by 95

Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

Hu, Y., Shi, Y., Chen, H., Tao, M., Zhou, X., Li, J., Ma, X., Wang, Y., & Liu, N. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.858494 · Cited by 98

Molecular machinery of macroautophagy and its deregulation in diseases

Wong, A. S. L., Cheung, Z. H., & Ip, N. Y. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.07.005 · Cited by 95

Autophagic pathways and metabolic stress

Kaushik, S., Singh, R., & Cuervo, A. M. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01263.x · Cited by 95

CD47 deficiency confers cell and tissue radioprotection by activation of autophagy

Soto‐Pantoja, D. R., Miller, T. W., Pendrak, M. L., DeGraff, W., Sullivan, C., Ridnour, L. A., Abu-Asab, M. S., Wink, D. A., Tsokos, M., & Roberts, D. D. (2012) · Autophagy · doi:10.4161/auto.21562 · Cited by 95

Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK

Dai, S., Dulcey, A. E., Hu, X., Wassif, C. A., Porter, F. D., Austin, C. P., Ory, D. S., Marugán, J., & Zheng, W. (2017) · Autophagy · doi:10.1080/15548627.2017.1329081 · Cited by 95

Autophosphorylation Within the Atg1 Activation Loop Is Required for Both Kinase Activity and the Induction of Autophagy in Saccharomyces cerevisiae

Yeh, Y.-Y., Wrasman, K., & Herman, P. K. (2010) · Genetics · doi:10.1534/genetics.110.116566 · Cited by 94

Autophagy, its mechanisms and regulation: Implications in neurodegenerative diseases

Moloudizargari, M., Asghari, M. H., Ghobadi, E., Fallah, M., Rasouli, S., & Abdollahi, M. R. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2017.09.005 · Cited by 94

Selective Acetogenins and Their Potential as Anticancer Agents

Jacobo-Herrera, N. J., Pérez‐Plasencia, C., Castro‐Torres, V. A., Martínez‐Vázquez, M., González‐Esquinca, A. R., & Zentella‐Dehesa, A. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00783 · Cited by 94

Insights into the toxicity and biodegradation of fipronil in contaminated environment

Bhatt, P., Gangola, S., Ramola, S., Bilal, M., Bhatt, K., Huang, Y., Zhou, Z., & Chen, S. (2022) · Microbiological Research · doi:10.1016/j.micres.2022.127247 · Cited by 94

Broad-spectrum antiviral agents

Zhu, J., Meng, W., Wang, X.-J., & Wang, H. R. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00517 · Cited by 94

Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein

Boland, B., Smith, D. A., Mooney, D., Jung, S. S., Walsh, D. M., & Platt, F. M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.186411 · Cited by 93

A Dual Role for Receptor-interacting Protein Kinase 2 (RIP2) Kinase Activity in Nucleotide-binding Oligomerization Domain 2 (NOD2)-dependent Autophagy

Homer, C. R., Kabi, A., Marina–García, N., Sreekumar, A., Nesvizhskii, A. I., Nickerson, K. P., Chinnaiyan, A. M., Núñez, G., & McDonald, C. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.326835 · Cited by 93

Defects in Mitochondrial Clearance Predispose Human Monocytes to Interleukin-1β Hypersecretion

van der Burgh, R., Nijhuis, L., Pervolaraki, K., Compeer, E. B., Jongeneel, L. H., van Gijn, M. E., Coffer, P. J., Murphy, M. P., Mastroberardino, P. G., Frenkel, J., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.536920 · Cited by 93

MALAT1 modulates the autophagy of retinoblastoma cell through miR‐124‐mediated stx17 regulation

Huang, J. X., Yang, Y., Fang, F., & Liu, K. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26464 · Cited by 93

Autophagy and pulmonary disease

Liao, S., Sun, P., Gu, Y., Rao, X., Zhang, L., & Ouyang, Y. (2019) · Therapeutic Advances in Respiratory Disease · doi:10.1177/1753466619890538 · Cited by 94

Diminished Parkin Solubility and Co-Localization with Intraneuronal Amyloid-β are Associated with Autophagic Defects in Alzheimer's Disease

Lonskaya, I., Shekoyan, A. R., Hebron, M. L., Desforges, N. M., Algarzae, N. K., & Moussa, C. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-121141 · Cited by 93

Beclin 1 Complex in Autophagy and Alzheimer Disease

Jaeger, P. A., & Wyss‐Coray, T. (2010) · Archives of Neurology · doi:10.1001/archneurol.2010.258 · Cited by 93

Autophagy regulates inflammation following oxidative injury in diabetes

Wang, Y., Li, Y., Yin, J.-J., Wang, Y., Zhu, L., Xie, G., & Pan, S. (2013) · Autophagy · doi:10.4161/auto.23628 · Cited by 93

Functions of Autophagy in Pathological Cardiac Hypertrophy

Li, Z., Wang, J., & Yang, X. Y. (2015) · International Journal of Biological Sciences · doi:10.7150/ijbs.11883 · Cited by 93

Hints on ATGL implications in cancer: beyond bioenergetic clues

Vegliante, R., Leo, L. D., Ciccarone, F., & Ciriolo, M. R. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0345-z · Cited by 93

The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity

Oliva, L., Orfanelli, U., Resnati, M., Raimondi, A., Orsi, A., Milan, E., Palladini, G. O., Milani, P., Cerruti, F., Cascio, P., et al. (2017) · Blood · doi:10.1182/blood-2016-08-730978 · Cited by 92

Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy

Buraschi, S., Neill, T., & Iozzo, R. V. (2017) · Matrix Biology · doi:10.1016/j.matbio.2017.10.005 · Cited by 92

Response to Persistent ER Stress in Plants: A Multiphasic Process That Transitions Cells from Prosurvival Activities to Cell Death

Srivastava, R., Li, Z., Russo, G., Tang, J., Bi, R., Muppirala, U. K., Chudalayandi, S., Severin, A. J., He, M., Vaitkevicius, S. I., et al. (2018) · The Plant Cell · doi:10.1105/tpc.18.00153 · Cited by 92

Improved efficacy of a next-generation ERT in murine Pompe disease

Xu, S., Lun, Y., Frascella, M., Garcia, A., Soska, R., Nair, A., Ponery, A. S., Schilling, A. E., Feng, J., Tuske, S. J., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.125358 · Cited by 92

Dysregulation of Intestinal Epithelial Cell RIPK Pathways Promotes Chronic Inflammation in the IBD Gut

Garcia‐Carbonell, R., Yao, S.-J., Das, S., & Gumá, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01094 · Cited by 92

Autophagy as a Potential Therapy for Malignant Glioma

Escamilla-Ramírez, Á., Castillo‐Rodríguez, R. A., Zavala-Vega, S., Jiménez‐Farfán, D., Anaya‐Rubio, I., Briseño, E., Palencia, G., Guevara, P., Cruz-Salgado, A., Sotelo, J., et al. (2020) · Pharmaceuticals · doi:10.3390/ph13070156 · Cited by 94

Control of Oxidative Stress in Cancer Chemoresistance: Spotlight on Nrf2 Role

Barrera, G., Cucci, M. A., Grattarola, M., Dianzani, C., Muzio, G., & Pizzimenti, S. (2021) · Antioxidants · doi:10.3390/antiox10040510 · Cited by 92

Knockdown of estrogen receptor‐α induces autophagy and inhibits antiestrogen‐mediated unfolded protein response activation, promoting ROS‐induced breast cancer cell death

Cook, K. L., Clarke, P. A. G., Parmar, J. H., Hu, R., Schwartz‐Roberts, J. L., Abu-Asab, M. S., Wärri, A. M., Baumann, W. T., & Clarke, R. C. (2014) · The FASEB Journal · doi:10.1096/fj.13-247353 · Cited by 92

Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

Chen, S., Zhou, L., Zhang, Y., Leng, Y., Pei, X.-Y., Lin, H., Jones, R., Orlowski, R. Z., Dai, Y., & Grant, S. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.01383-13 · Cited by 92

Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury

Chandrika, B. B., Yang, C., Ou, Y., Feng, X., Muhoza, D., Holmes, A. F., Theus, S. A., Deshmukh, S., Haun, R. S., & Kaushal, G. P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140025 · Cited by 92

ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance

Liu, K., Zhao, Q., Liu, P., Cao, J., Gong, J., Wang, C., Wang, W., Li, X., Sun, H., Zhang, C., et al. (2016) · Autophagy · doi:10.1080/15548627.2016.1212786 · Cited by 92

Oxidative/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis

Hosseinzadeh, A., Javad-Moosavi, S. A., Reiter, R. J., Yarahmadi, R., Ghaznavi, H., & Mehrzadi, S. (2018) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2018.1541318 · Cited by 91

A review of arsenic exposure and lung cancer

Wei, S., Zhang, H., & Tao, S. (2019) · Toxicology Research · doi:10.1039/c8tx00298c · Cited by 91

Intracellular calcium signaling regulates autophagy via calcineurin-mediated TFEB dephosphorylation

Tong, Y., & Song, F. (2015) · Autophagy · doi:10.1080/15548627.2015.1054594 · Cited by 91

Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells

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Lysosomal Transmembrane Protein LAPTM4B Promotes Autophagy and Tolerance to Metabolic Stress in Cancer Cells

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Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine

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