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Cited by 398

The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.

Early Events in B Cell Activation

Harwood, Naomi E., Batista, Facundo D.·2010·Annual Review of Immunology

Abstract

B cell activation is initiated by the ligation of the B cell receptor (BCR) with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here we review recent literature concerned with the spatiotemporal dynamic characterization of the early molecular events of B cell activation, including the initiation of BCR triggering, the formation of BCR microclusters, and the dynamic regulation of BCR signaling. Because these events involve the considerable reorganization of molecules within the membrane, an important role for the cytoskeleton is emerging in the regulation of B cell activation. At each stage we highlight the role of the cytoskeleton, establishing its pivotal position during the initiation and regulation of B cell activation.

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Crossref · 10.1146/annurev-immunol-030409-101216

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Metadata

Authors
Harwood, N. E., & Batista, F. D.
Venue
Annual Review of Immunology
Published
2010-03-01
Volume
28
Issue
1
Pages
185-210
ISSN
  • 0732-0582 (ISSN-L)
  • 1545-3278
OpenAlex
W2167423357
Cited by
398
References
147
FWCI
1.76
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Early Events in B Cell Activation. https://app.cochat.ai/papers/10.1146/annurev-immunol-030409-101216
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Harwood, N. E., & Batista, F. D. (2010). Early Events in B Cell Activation. Annual Review of Immunology. https://doi.org/10.1146/annurev-immunol-030409-101216

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.