The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

The regulation of IL-10 production by immune cells

Saraiva, M., & O’Garra, A. (2010) · Nature reviews. Immunology · doi:10.1038/nri2711 · Cited by 3,293

Innate lymphoid cells — a proposal for uniform nomenclature

Spits, H., Artis, D., Colonna, M., Diefenbach, A., Disanto, J. D., Eberl, G., Koyasu, S., Locksley, R., McKenzie, A., Mebius, R., et al. (2013) · Nature reviews. Immunology · doi:10.1038/nri3365 · Cited by 2,380

Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature · doi:10.1038/nature09380 · Cited by 1,939

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature · doi:10.1038/nature10491 · Cited by 1,898

Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals

Denison, M. S., & Nagy, S. R. (2003) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.135828 · Cited by 1,895

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

Quintana, F. J., Basso, A. S., Iglesias, A. H., Korn, T., Farez, M. F., Bettelli, E., Caccamo, M., Oukka, M., & Weiner, H. L. (2008) · Nature · doi:10.1038/nature06880 · Cited by 1,865

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

Mezrich, J. D., Fechner, J. H., Zhang, X., Johnson, B. P., Burlingham, W. J., & Bradfield, C. A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903670 · Cited by 1,674

Innate IL-17-producing cells: the sentinels of the immune system

Cua, D. J., & Tato, C. M. (2010) · Nature reviews. Immunology · doi:10.1038/nri2800 · Cited by 1,640

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

Veldhoen, M., Hirota, K., Westendorf, A. M., Buer, J., Dumoutier, L., Renauld, J.-C., & Stockinger, B. (2008) · Nature · doi:10.1038/nature06881 · Cited by 1,634

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

Wang, Z., Zang, C., Cui, K., Schones, D. E., Barski, A., Peng, W., & Zhao, K. (2009) · Cell · doi:10.1016/j.cell.2009.06.049 · Cited by 1,344

Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting

Puccetti, M., Pariano, M., Renga, G., Santarelli, I., D’Onofrio, F., Bellet, M. M., Stincardini, C., Bartoli, A., Costantini, C., Romani, L. R., et al. (2021) · Cells · doi:10.3390/cells10071601 · Cited by 28

New insights into benzo[⍺]pyrene osteotoxicity in zebrafish

Tarasco, M., Gavaia, P. J., Bensimon‐Brito, A., Cardeira-da-Silva, J., Ramkumar, S., Cordelières, F. P., Günther, S., Bebianno, M. J., Stainier, D. Y. R., Cancela, M. L., et al. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112838 · Cited by 27

Therapeutic potential of targeting kynurenine pathway in neurodegenerative diseases

Shen, H., Xu, X., Bai, Y., Wang, X., Wu, Y., Zhong, J., Wu, Q., Luo, Y., Shang, T., Shen, R., et al. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115258 · Cited by 27

Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

Li, M., Tian, F., Guo, J., Li, X., Ma, L., Jiang, M., & Zhao, J. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1243820 · Cited by 27

Naturally Occurring Marine Brominated Indoles Are Aryl Hydrocarbon Receptor Ligands/Agonists

DeGroot, D. E., Franks, D. G., Higa, T., Tanaka, J., Hahn, M. E., & Denison, M. S. (2015) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00003 · Cited by 28

The aryl hydrocarbon receptor regulates the expression of TIPARP and its cis long non-coding RNA, TIPARP-AS1

Grimaldi, G., Rajendra, S., & Matthews, J. B. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.12.113 · Cited by 27

Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22

Rekik, R., Khanfir, M. S., Larbi, T., Zamali, I., Beldi‐Ferchiou, A., Kammoun, O., Marzouki, S., Hamzaoui, S., Mrad, S., Barbouche, M., et al. (2018) · Cytokine · doi:10.1016/j.cyto.2018.04.011 · Cited by 27

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

Villa, M., Crotta, S., Dingwell, K. S., Hirst, E. M. A., Gialitakis, M., Ahlfors, H., Smith, J. C., Stockinger, B., & Wack, A. (2016) · Nature Communications · doi:10.1038/ncomms12652 · Cited by 28

Aryl hydrocarbon receptor (AHR) functions in NAD+ metabolism, myelopoiesis and obesity

Bock, K. W. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.02.021 · Cited by 26

Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model

Tian, C., Zhang, G., Xia, Z., Chen, N., Yang, S., & Li, L. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114122 · Cited by 28

Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

Avancini, D., Testori, A., Fresolone, L., Andolfi, G., Vuono, M., Martinelli, V., de Sio, F. R. S., & Gregori, S. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112193 · Cited by 31

Aryl Hydrocarbon Receptor–Dependent Pathways in Immune Regulation

Gargaro, M., Pirro, M., Romani, R., Zelante, T., & Fallarino, F. (2016) · American Journal of Transplantation · doi:10.1111/ajt.13716 · Cited by 24

Impaired glucose and lipid metabolism in ageing aryl hydrocarbon receptor deficient mice

Biljes, D., Hammerschmidt-Kamper, C., Kadow, S., Diel, P. R., Weigt, C., Burkart, V., & Esser, C. (2015) · EXCLI journal · doi:10.17179/excli2015-638 · Cited by 26

FICZ generates human tDCs that induce CD4+ CD25high Foxp3+ Treg-like cell differentiation

Jurado-Manzano, B. B., Reyes, D. Z., Turrubiartes-Martínez, E., Portales‐Pérez, D. P., González‐Amaro, R., & Layseca‐Espinosa, E. (2017) · Immunology Letters · doi:10.1016/j.imlet.2017.07.013 · Cited by 26

Gastrodin ameliorates ulcerative colitis via modulating gut microbial tryptophan metabolism and AhR/NLRP3 pathway

Zhang, D., Wu, J., Feng, H., Tang, P., Zhou, Y., Zhao, C., Liu, J., Feng, W., & Peng, C. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157217 · Cited by 28

Tryptophan metabolism in health and disease- implications for non-communicable diseases

Gabela, A. M., Mthembu, N., & Hadebe, S. (2025) · Immunology Letters · doi:10.1016/j.imlet.2025.107093 · Cited by 31

Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model

Suwannasual, U., Lucero, J., Davis, G., McDonald, J. D., & Lund, A. K. (2019) · Toxicological Sciences · doi:10.1093/toxsci/kfz121 · Cited by 25

Epigenetic Regulations of AhR in the Aspect of Immunomodulation

Wajda, A., Łapczuk-Romańska, J., & Paradowska‐Gorycka, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176404 · Cited by 29

The Aryl hydrocarbon receptor mediates reproductive toxicity of polychlorinated biphenyl congener 126 in rats

Klenov, V. E., Flor, S., Ganesan, S., Adur, M. K., Eti, N. A., Iqbal, K., Soares, M. J., Ludewig, G., Ross, J. W., Robertson, L. W., et al. (2021) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2021.115639 · Cited by 26

Type II alveolar epithelial cell aryl hydrocarbon receptor protects against allergic airway inflammation through controlling cell autophagy

Wang, J., Zhao, Y., Zhang, X., Tu, W., Wan, R., Shen, Y., Zhang, Y., Trivedi, R., & Gao, P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.964575 · Cited by 28

Oxidative stress modulates expression of immune checkpoint genes via activation of AhR signaling

Kou, Z., Yang, R., Lee, E., Cuddapah, S., Choi, B. H., & Dai, W. (2022) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2022.116314 · Cited by 25

Indole-3-pyruvic acid alleviates rheumatoid arthritis via the aryl hydrocarbon receptor pathway

Huang, T., Cheng, L., Jiang, Y. J., Zhang, L., & Qian, L. (2023) · Annals of Translational Medicine · doi:10.21037/atm-23-1074 · Cited by 28

Microbial metabolites and immunotherapy: Basic rationale and clinical indications

Kovtonyuk, L. V., & McCoy, K. D. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101755 · Cited by 25

Ah receptor ligands and their impacts on gut resilience: structure–activity effects

Safe, S. H., Jayaraman, A., & Chapkin, R. S. (2020) · Critical Reviews in Toxicology · doi:10.1080/10408444.2020.1773759 · Cited by 26

Activation of aryl hydrocarbon receptor by 6‐formylindolo[3,2‐b]carbazole alleviated acute kidney injury by repressing inflammation and apoptosis

Tao, S., Guo, F., Ren, Q., Liu, J., Wei, T., Li, L., Ma, L., & Fu, P. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16168 · Cited by 25

Genome-wide transcriptional analysis reveals novel AhR targets that regulate dendritic cell function during influenza A virus infection

Franchini, A. M., Myers, J. R., Jin, G.-B., Shepherd, D. M., & Lawrence, B. P. (2019) · ImmunoHorizons · doi:10.4049/immunohorizons.1900004 · Cited by 23

Oil mistparticulate matter exposure induces hyperlipidemia-related inflammation via microbiota/ SCFAs/GPR43 axis inhibition and TLR4/NF-κB activation

Liu, H., Nie, H., Shi, Y., Lai, W., Bian, L., Tian, L., Li, K., Xi, Z., & Lin, B. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123331 · Cited by 26

Modulation of Host Immunity by Microbiome‐Derived Indole‐3‐Propionic Acid and Other Bacterial Metabolites

Schütz, B., Krause, F. F., Taudte, R. V., Zaiss, M. M., Luu, M., & Visekruna, A. (2025) · European Journal of Immunology · doi:10.1002/eji.202451594 · Cited by 29

The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma

Sarić, N., Selby, M. P., Ramaswamy, V., Kool, M., Stockinger, B., Högstrand, C., Williamson, D., Marino, S., Taylor, M. D., Clifford, S. C., et al. (2020) · Scientific Reports · doi:10.1038/s41598-019-56876-z · Cited by 28

Tryptophan in the diet ameliorates motor deficits in a rotenone‐induced rat Parkinson's disease model via activating the aromatic hydrocarbon receptor pathway

Wang, Y., Chen, S., Tan, J., Gao, Y., Yan, H., Liu, Y., Yi, S., Xiao, Z., & Wu, H. (2021) · Brain and Behavior · doi:10.1002/brb3.2226 · Cited by 24

Pharmacological Modulation of Immune Responses by Nutritional Components

van Daal, M. T., Folkerts, G., Garssen, J., & Braber, S. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000063 · Cited by 24

AhR–STAT3–HO‐1/COX‐2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver

Han, L., Ma, C., Wu, Z., Xu, H., Li, H., & Pan, G. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16208 · Cited by 26

Targeting aryl hydrocarbon receptor to prevent cancer in barrier organs

Congues, F., Wang, P., Lee, J., Lin, D., Shahid, A., Xie, J., & Huang, Y. S. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116156 · Cited by 29

Transcriptional Control of NK Cells

Sun, J. C.-Y. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_452 · Cited by 24

Potential involvement of placental AhR in unexplained recurrent spontaneous abortion

Wu, Y., Chen, X., Chang, X., Huang, Y., Bao, S., He, Q., Li, Y., Zheng, J., Duan, T., & Wang, K. (2015) · Reproductive Toxicology · doi:10.1016/j.reprotox.2015.11.005 · Cited by 27

Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury

Richter, J., Jiménez, J., Nagatomo, T., Toelen, J., Brady, P., Salaets, T., Lesage, F., Vanoirbeek, J. A., & Deprest, J. A. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-1009-3 · Cited by 24

Pilot study of global endocrine disrupting activity in Iowa public drinking water utilities using cell-based assays

Jones, R. R., Stavreva, D. A., Weyer, P. J., Varticovski, L., Inoue‐Choi, M., Medgyesi, D. N., Chavis, N. S., Graubard, B. I., Cain, T. G., Wichman, M. D., et al. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.136317 · Cited by 24

Aryl hydrocarbon Receptor activation during in vitro and in vivo digestion of raw and cooked broccoli ( brassica oleracea var. Italica )

Koper, J. E. B., Kortekaas, M., Loonen, L. M. P., Huang, Z., Wells, J. M., Gill, C. I. R., Pourshahidi, L. K., McDougall, G. J., Rowland, I. R., Pereira‐Caro, G., et al. (2020) · Food & Function · doi:10.1039/d0fo00472c · Cited by 23

The aryl hydrocarbon receptor: An environmental effector in the pathogenesis of fibrosis

Shi, Y., Zeng, Z., Yu, J., Tang, B., Tang, R., & Xiao, R. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105180 · Cited by 23

Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation

Bock, K. W. (2021) · Archives of Toxicology · doi:10.1007/s00204-021-03134-9 · Cited by 23

Tryptophan Metabolism and COVID-19-Induced Skeletal Muscle Damage: Is ACE2 a Key Regulator?

Takeshita, H., & Yamamoto, K. I. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.868845 · Cited by 22

Aryl hydrocarbon receptor nuclear translocator (ARNT) isoforms control lymphoid cancer cell proliferation through differentially regulating tumor suppressor p53 activity

Gardella, K. A., Muro, I., Fang, G., Sarkar, K., Méndez-Solís, O., & Wright, C. W. (2016) · Oncotarget · doi:10.18632/oncotarget.7539 · Cited by 22

Modulation of the monocyte/macrophage system in heart failure by targeting heme oxygenase-1

Tomczyk, M., Kraszewska, I., Dulak, J., & Jaźwa, A. (2018) · Vascular Pharmacology · doi:10.1016/j.vph.2018.08.011 · Cited by 24

NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice

Cheng, X., Haeberle, S., Shytaj, I. L., Gama-Brambila, R. A., Theobald, J., Ghafoory, S., Wölker, J., Basu, U., Schmidt, C., Timm, A., et al. (2020) · Communications Biology · doi:10.1038/s42003-019-0716-8 · Cited by 23

Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor

Choudhary, M., Safe, S. H., & Malek, G. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.02.015 · Cited by 23

Innate lymphoid cell sensing of tissue vitality

Barrow, A. D., & Colonna, M. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.11.004 · Cited by 22

Aryl hydrocarbon receptor expression in serum, peripheral blood mononuclear cells, and skin lesions of patients with atopic dermatitis and its correlation with disease severity

Hu, Y., Liu, P., Mu, Z., & Zhang, J. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000591 · Cited by 22

Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses

de Araújo, E. F., Preite, N. W., Veldhoen, M., Loures, F. V., & Calich, V. L. G. (2020) · Scientific Reports · doi:10.1038/s41598-020-68322-6 · Cited by 22

The Aryl Hydrocarbon Receptor–Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis

Cirac, A., Tsaktanis, T., Beyer, T., Linnerbauer, M., Andlauer, T. F. M., Grummel, V., Nirschl, L., Lößlein, L., Quintana, F. J., Hemmer, B., et al. (2021) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000001043 · Cited by 23

The aryl hydrocarbon receptor as a model PAS sensor

Vazquez-Rivera, E., Rojas, B. L., Parrott, J. C., Shen, A. L., Xing, Y., Carney, P. R., & Bradfield, C. A. (2021) · Toxicology Reports · doi:10.1016/j.toxrep.2021.11.017 · Cited by 22

Naringenin protects against acute pancreatitis-associated intestinal injury by inhibiting NLRP3 inflammasome activation via AhR signaling

Xu, Y. H., Lin, T., Zhu, Q., Zhang, Y., Song, Z., & Pan, X. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1090261 · Cited by 22

The gastrointestinal-brain-microbiota axis: a promising therapeutic target for ischemic stroke

Wei, Y., Bi, R., Qiu, Y., Zhang, C., Li, J., Li, Y., & Hu, B. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1141387 · Cited by 26

Innate lymphoid cells: a new key player in atopic dermatitis

Jia, H., Wan, H., & Zhang, D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1277120 · Cited by 23

Amino acid metabolic reprogramming in the tumor microenvironment and its implication for cancer therapy

Zhang, J., Chen, M., Yang, Y., Liu, Z., Guo, W., Xiang, P., Zeng, Z., Wang, D., & Xiong, W. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31349 · Cited by 23

The Role of Indirubins in Inflammation and Associated Tumorigenesis

Cheng, X., & Merz, K. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-41342-6_12 · Cited by 24

Sensing of physiological regulators by innate lymphoid cells

Seillet, C., & Jacquelot, N. (2019) · Cellular and Molecular Immunology · doi:10.1038/s41423-019-0217-1 · Cited by 22

Short‐term and long‐term outcomes of indigo naturalis treatment for inflammatory bowel disease

Matsuno, Y., Hirano, A., Torisu, T., Okamoto, Y., Fuyuno, Y., Fujioka, S., Umeno, J., Moriyama, T., Nagai, S., Hori, Y., et al. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14823 · Cited by 22

Bacterial Metabolites and Inflammatory Skin Diseases

Jiminez, V. S., & Yusuf, N. (2023) · Metabolites · doi:10.3390/metabo13080952 · Cited by 23

Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells

Li, B., Liang, X. S., Li, Y., Wang, R., Wei, Y., Liu, Q., Zhang, J., Wang, Q., Miao, Q., Xiao, X., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2557979 · Cited by 23

Serum Levels of Aryl Hydrocarbon Receptor, Cytochromes P450 1A1 and 1B1 in Patients with Exacerbated Psoriasis Vulgaris

Beránek, M., Fiala, Z., Kremláček, J., Andrýs, C., Krejsek, J., Hamáková, K., Palička, V., & Borská, L. (2018) · Folia Biologica · doi:10.14712/fb2018064030097 · Cited by 21

Anti-Aging Physiological Roles of Aryl Hydrocarbon Receptor and Its Dietary Regulators

Serna, E., Cespedes, C., & Viña, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010374 · Cited by 21

Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells

Almeida-da-Silva, C. L. C., Dakafay, H. M., Liu, K., & Ojcius, D. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147669 · Cited by 21

Th17 cells in the liver: balancing autoimmunity and pathogen defense

Taniki, N., Nakamoto, N., Chu, P., Ichikawa, M., Teratani, T., & Kanai∥, T. (2022) · Seminars in Immunopathology · doi:10.1007/s00281-022-00917-9 · Cited by 22

Metabolic regulation of immune responses to cancer

Wißfeld, J., Werner, A., Yan, X., ten Bosch, N., & Cui, G. (2022) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2022.0381 · Cited by 21

Zhizhu decoction alleviates slow transit constipation by regulating aryl hydrocarbon receptor through gut microbiota

Wen, Y., Zhan, Y., Tang, S., Liu, F., Wu, R., Kong, P., Li, Q., & Tang, X. (2022) · Pharmaceutical Biology · doi:10.1080/13880209.2022.2157020 · Cited by 23

Evolutionary Physiology and Genomics in the Highly Adaptable Killifish ( Fundulus heteroclitus )

Crawford, D. L., Schulte, P. M., Whitehead, A., & Oleksiak, M. F. (2020) · Comprehensive physiology · doi:10.1002/cphy.c190004 · Cited by 23

A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR

Xu, M., Mehl, L. C., Zhang, T., Thakur, R., Sowards, H., Myers, T. A., Jessop, L., Chesi, A., Johnson, M. E., Wells, A. D., et al. (2021) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2021.07.002 · Cited by 17

Aryl hydrocarbon receptor–targeted therapy for CD4+ T cell–mediated idiopathic pneumonia syndrome in mice

Lee, S.-M., Kim, C. E., Park, H. Y., Yoon, E. H., Won, H. J., Ahn, J. M., Nguyen, N. Z. N., Kim, M., Jang, W. H., Lee, W. S., et al. (2022) · Blood · doi:10.1182/blood.2021013849 · Cited by 20

Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation

Alessandrini, F., de Jong, R., Wimmer, M., Maier, A.-M., Fernandez, I. E., Hils, M., Buters, J., Biedermann, T., Zissler, U. M., Hoffmann, C., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.901194 · Cited by 20

Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro

Groestlinger, J., Seidl, C., Varga, E., Favero, G. D., & Marko, D. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.882222 · Cited by 20

Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

Yang, C., Wierbiłowicz, K., Dworak, N. M., Bae, S. Y., Tengse, S. B., Abianeh, N., Drake, J. M., Abbas, T., Ratan, A., Wotton, D., et al. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0086 · Cited by 20

The double-edged sword effect of indigo naturalis

Xu, Y., Lin, C., Tan, H., & Bian, Z. (2024) · Food and Chemical Toxicology · doi:10.1016/j.fct.2024.114476 · Cited by 19

Cellular and molecular pathways through which commensal bacteria modulate sensitization to dietary antigens

Feehley, T., & Nagler‐Anderson, C. (2014) · Current Opinion in Immunology · doi:10.1016/j.coi.2014.10.001 · Cited by 20

Brain inflammatory cascade controlled by gut-derived molecules

Wekerle, H. (2018) · Nature · doi:10.1038/d41586-018-05113-0 · Cited by 20

Transcriptome Profiling Reveals Indoxyl Sulfate Should Be Culpable of Impaired T Cell Function in Chronic Kidney Disease

Xiang, F., Cao, X., Shen, B., Chen, X., Guo, M., Ding, X., & Zou, J. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00178 · Cited by 20

AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes

Wang, L., Cheng, B., Ju, Q., & Sun, B. K. (2021) · Journal of Innate Immunity · doi:10.1159/000517627 · Cited by 20

Gut microbiota in cancer initiation, development and therapy

Zhang, R., Zhang, X., Lau, H. C.-H., & Yu, J. Q. (2024) · Science China Life Sciences · doi:10.1007/s11427-024-2831-x · Cited by 19

AhR governs lipid metabolism: the role of gut microbiota

Zheng, W., Liu, M., Lv, X., He, C., Yin, J., & Ma, J. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1442282 · Cited by 21

The regulatory effects and mechanisms of plant food-derived bioactive components on gut barrier function and intestinal homeostasis: a comprehensive review

Xie, P., Ma, Z., Yang, X., Pan, H., Shen, P., Du, H., Cao, Y., Xiao, J., Xiao, H., & Song, M. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2481983 · Cited by 20

Aryl Hydrocarbon Receptor in Health and Disease

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