The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

The regulation of IL-10 production by immune cells

Saraiva, M., & O’Garra, A. (2010) · Nature reviews. Immunology · doi:10.1038/nri2711 · Cited by 3,293

Innate lymphoid cells — a proposal for uniform nomenclature

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Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature · doi:10.1038/nature09380 · Cited by 1,939

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature · doi:10.1038/nature10491 · Cited by 1,898

Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals

Denison, M. S., & Nagy, S. R. (2003) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.135828 · Cited by 1,895

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

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An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

Mezrich, J. D., Fechner, J. H., Zhang, X., Johnson, B. P., Burlingham, W. J., & Bradfield, C. A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903670 · Cited by 1,674

Innate IL-17-producing cells: the sentinels of the immune system

Cua, D. J., & Tato, C. M. (2010) · Nature reviews. Immunology · doi:10.1038/nri2800 · Cited by 1,640

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

Veldhoen, M., Hirota, K., Westendorf, A. M., Buer, J., Dumoutier, L., Renauld, J.-C., & Stockinger, B. (2008) · Nature · doi:10.1038/nature06881 · Cited by 1,634

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

Wang, Z., Zang, C., Cui, K., Schones, D. E., Barski, A., Peng, W., & Zhao, K. (2009) · Cell · doi:10.1016/j.cell.2009.06.049 · Cited by 1,344

The Microbial Pecking Order: Utilization of Intestinal Microbiota for Poultry Health

Maki, J. J., Klima, C. L., Sylte, M. J., & Looft, T. P. (2019) · Microorganisms · doi:10.3390/microorganisms7100376 · Cited by 130

Food Chemicals Disrupt Human Gut Microbiota Activity And Impact Intestinal Homeostasis As Revealed By In Vitro Systems

Defois, C., Ratel, J., Garrait, G., Denis, S., Goff, O. L., Talvas, J., Mosoni, P., Engel, E., & Peyret, P. (2018) · Scientific Reports · doi:10.1038/s41598-018-29376-9 · Cited by 128

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence

Tsatsakis, A. M., Petrakis, D., Νikolouzakis, Τ. Κ., Docea, A. O., Călina, D. C., Vinceti, M., Γούμενου, Μ., Kostoff, R. N., Mamoulakis, C., Aschner, M., et al. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111418 · Cited by 130

Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity

Haas, K., Weighardt, H., Deenen, R., Köhrer, K., Clausen, B., Zahner, S., Boukamp, P., Bloch, W., Krutmann, J., & Esser, C. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.06.627 · Cited by 125

Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models

Oesch, F., Fabian, E. J., Guth, K., & Landsiedel, R. (2014) · Archives of Toxicology · doi:10.1007/s00204-014-1382-8 · Cited by 123

Evidence for New Light-Independent Pathways for Generation of the Endogenous Aryl Hydrocarbon Receptor Agonist FICZ

Smirnova, A. V., Wincent, E., Bergander, L. V., Alsberg, T. E., Bergman, J., Rannug, A., & Rannug, U. (2015) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00416 · Cited by 125

The Role of PARPs in Inflammation—And Metabolic—Related Diseases: Molecular Mechanisms and Beyond

Ke, Y., Wang, C., Zhang, J., Zhong, X., Wang, R., Zeng, X., & Ba, X. (2019) · Cells · doi:10.3390/cells8091047 · Cited by 124

Endothelial AHR activity prevents lung barrier disruption in viral infection

Major, J., Crotta, S., Finsterbusch, K., Chakravarty, P., Shah, K., Frederico, B., D’Antuono, R., Green, M. J., Meader, L., Suárez‐Bonnet, A., et al. (2023) · Nature · doi:10.1038/s41586-023-06287-y · Cited by 127

Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses

Merlo, L. M. F., DuHadaway, J. B., Montgomery, J. D., Peng, W., Murray, P. J., Prendergast, G. C., Caton, A. J., Muller, A. J., & Mandik‐Nayak, L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01861 · Cited by 124

AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization

Yang, X., Liu, H., Ye, T., Duan, C., Lv, P., Wu, X., Liu, J., Jiang, K., Lu, H., Yang, H., et al. (2020) · Theranostics · doi:10.7150/thno.51144 · Cited by 124

Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation

Kawai, S., Iijima, H., Shinzaki, S., Hiyama, S., Yamaguchi, T., Araki, M., Iwatani, S., Shiraishi, E., Mukai, A., Inoue, T., et al. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1292-z · Cited by 120

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer

Kubli, S. P., Bassi, C., Roux, C., Wakeham, A. C., Göbl, C., Zhou, W., Jafari, S. M., Snow, B. E., Jones, L., Palomero, L., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1815126116 · Cited by 116

Role for diet in normal gut barrier function: developing guidance within the framework of food-labeling regulations

Camilleri, M., Lyle, B. J., Madsen, K. L., Sonnenburg, J. L., Verbeke, K., & Wu, G. D. (2019) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00063.2019 · Cited by 115

Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon Cancer

Greathouse, K. L., & Wyatt, M. (2021) · Nutrients · doi:10.3390/nu13041189 · Cited by 116

The aryl hydrocarbon receptor controls cell-fate decisions in B cells

Vaidyanathan, B., Chaudhry, A., Yewdell, W. T., Angeletti, D., Yen, W.-F., Wheatley, A. K., Bradfield, C. A., McDermott, A. B., Yewdell, J. W., Rudensky, A. Y., et al. (2016) · The Journal of Experimental Medicine · doi:10.1084/jem.20160789 · Cited by 116

Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functions

Bock, K. W. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.06.015 · Cited by 114

Amino Acid Trp: The Far Out Impacts of Host and Commensal Tryptophan Metabolism

Grifka‐Walk, H. M., Jenkins, B. R., & Kominsky, D. J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.653208 · Cited by 115

Modeling the binding of diverse ligands within the Ah receptor ligand binding domain

Giani Tagliabue, S., Faber, S. C., Motta, S., Denison, M. S., & Bonati, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-47138-z · Cited by 106

A dysregulated sebum–microbial metabolite–IL-33 axis initiates skin inflammation in atopic dermatitis

Qiu, Z., Zhu, Z., Liu, X., Chen, B., Yin, H., Gu, C., Fang, X., Zhu, R., Yu, T., Mi, W., et al. (2022) · The Journal of Experimental Medicine · doi:10.1084/jem.20212397 · Cited by 110

Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis

Alrouji, M., Manouchehrinia, A., Gran, B., & Constantinescu, C. S. (2018) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2018.10.004 · Cited by 110

20 Years of fish immunotoxicology – what we know and where we are

Rehberger, K., Werner, I., Hitzfeld, B., Segner, H. E., & Baumann, L. (2017) · Critical Reviews in Toxicology · doi:10.1080/10408444.2017.1288024 · Cited by 103

Regulation of Astrocyte Functions in Multiple SclerosisPreprint

Wheeler, M. A., & Quintana, F. J. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029009 · Cited by 103

Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

Manzella, C. R., Singhal, M., Alrefai, W. A., Saksena, S., Dudeja, P. K., & Gill, R. K. (2018) · Scientific Reports · doi:10.1038/s41598-018-24213-5 · Cited by 102

Indole Propionic Acid, an Unusual Antibiotic Produced by the Gut Microbiota, With Anti-inflammatory and Antioxidant Properties

Negatu, D. A., Gengenbacher, M., Dartois, V. A., & Dick, T. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.575586 · Cited by 108

Indole compounds may be promising medicines for ulcerative colitis

Sugimoto, S., Naganuma, M., & Kanai∥, T. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1220-2 · Cited by 101

The complex biology of aryl hydrocarbon receptor activation in cancer and beyond

Opitz, C. A., Holfelder, P., Prentzell, M. T., & Trump, S. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115798 · Cited by 109

High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism

Vacher, S., Castagnet, P., Chemlali, W., Lallemand, F., Meseure, D., Pocard, M. D., Bièche, I., & Perrot‐Applanat, M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190619 · Cited by 103

The role of AhR in transcriptional regulation of immune cell development and function

Trikha, P., & Lee, D. A. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2019.188335 · Cited by 96

Dietary and Microbial Determinants in Food Allergy

Victor, E. S., Crestani, E., & Chatila, T. A. (2020) · Immunity · doi:10.1016/j.immuni.2020.07.025 · Cited by 101

Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities

Pastor-Fernández, G., Mariblanca, I. R., & Navarro, M. N. (2020) · Cells · doi:10.3390/cells9092044 · Cited by 102

Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study

Sugimoto, S., Naganuma, M., Kiyohara, H., Arai, M., Ono, K., Mori, K., Saigusa, K., Nanki, K., Takeshita, K., Takeshita, T., et al. (2016) · Digestion · doi:10.1159/000444217 · Cited by 100

Host/microbiota interactions-derived tryptophan metabolites modulate oxidative stress and inflammation via aryl hydrocarbon receptor signaling

Tan, Y.-Q., Wang, Y., Feng, H.-Y., Guo, Z.-Y., Li, X., Nie, X.-L., & Zhao, Y. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.03.025 · Cited by 100

The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities

Mikó, É., Csaszar, A., Bódis, J., & Kovács, K. A. (2022) · Life · doi:10.3390/life12030424 · Cited by 103

Aryl hydrocarbon receptor is required for optimal B‐cell proliferation

Villa, M., Gialitakis, M., Tolaini, M., Ahlfors, H., Henderson, C. J., Wolf, C. R., Brink, R. A., & Stockinger, B. (2016) · The EMBO Journal · doi:10.15252/embj.201695027 · Cited by 92

Control of immune-mediated pathology via the aryl hydrocarbon receptor

Wheeler, M. A., Rothhammer, V., & Quintana, F. J. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r116.767723 · Cited by 95

Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases

Ghiboub, M., Verburgt, C. M., Sovran, B., Benninga, M. A., de Jonge, W. J., & Limbergen, J. V. (2020) · Nutrients · doi:10.3390/nu12092846 · Cited by 97

Immunotoxic, genotoxic, and endocrine disrupting impacts of polyamide microplastic particles and chemicals

Alijagić, A., Kotlyar, O., Larsson, M., Salihović, S., Hedbrant, A., Eriksson, U., Karlsson, P. G., Persson, A., Scherbak, N. N., Färnlund, K., et al. (2023) · Environment International · doi:10.1016/j.envint.2023.108412 · Cited by 92

The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation

Polonio, C. M., McHale, K. A., Sherr, D. H., Rubenstein, D., & Quintana, F. J. (2025) · Nature Reviews Drug Discovery · doi:10.1038/s41573-025-01172-x · Cited by 104

Breast Milk and Solid Food Shaping Intestinal Immunity

Parigi, S. M., Eldh, M., Larssen, P., Gabrielsson, S., & Villablanca, E. J. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00415 · Cited by 97

Overview on the Prevalence of Fungal Infections, Immune Response, and Microbiome Role in COVID-19 Patients

Roudbary, M., Kumar, S., Kumar, A., Černáková, L., Nikoomanesh, F., & Rodrigues, C. F. (2021) · Journal of Fungi · doi:10.3390/jof7090720 · Cited by 89

The aryl hydrocarbon receptor: structure, signaling, physiology and pathology

Coumoul, X., Barouki, R., Esser, C., Haarmann‐Stemmann, T., Lawrence, B. P., Lehmann, J., Moura‐Alves, P., Murray, I. A., Opitz, C. A., Perdew, G. H., et al. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02500-8 · Cited by 111

The case of tryptamine and serotonin in plants: a mysterious precursor for an illustrious metabolite

Negri, S., Commisso, M., Avesani, L., & Guzzo, F. (2021) · Journal of Experimental Botany · doi:10.1093/jxb/erab220 · Cited by 90

Microbiota control of a tryptophan–AhR pathway in disease tolerance to fungi

Romani, L. R., Zelante, T., LUCA, A. D., Iannitti, R. G., Moretti, S., Bartoli, A., Aversa, F., & Puccetti, P. (2014) · European Journal of Immunology · doi:10.1002/eji.201344406 · Cited by 93

Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation

Chen, Y., Wang, Y., Fu, Y., Yin, Y., & Xu, K. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01046-y · Cited by 92

Extreme environments and the origins of biodiversity: Adaptation and speciation in sulphide spring fishes

Tobler, M., Kelley, J. L., Plath, M. W., & Riesch, R. (2018) · Molecular Ecology · doi:10.1111/mec.14497 · Cited by 88

Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review

Silverberg, J. I., Boguniewicz, M., Quintana, F. J., Clark, R. A., Gross, L., Hirano, I., Tallman, A. M., Brown, P. M., Fredericks, D., Rubenstein, D. S., et al. (2023) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2023.12.013 · Cited by 94

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value

Román, Á., Carvajal-González, J. M., Merino, J. M., Mulero‐Navarro, S., & Fernández‐Salguero, P. M. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.12.003 · Cited by 89

Cytokine Networks between Innate Lymphoid Cells and Myeloid Cells

Mortha, A., & Burrows, K. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00191 · Cited by 88

From TCDD-mediated toxicity to searches of physiologic AHR functions

Bock, K. W. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.032 · Cited by 90

Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors

Barry, S., Carlsen, E., Marques, P., Stiles, C. E., Gadaleta, E., Berney, D. M., Roncaroli, F., Chelala, C., Solomou, A., Herincs, M., et al. (2019) · Oncogene · doi:10.1038/s41388-019-0779-5 · Cited by 84

CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway

Kyoreva, M., Li, Y., Hoosenally, M., Hardman, J. A., Morrison, K., Tosi, I., Tolaini, M., Barinaga, G., Stockinger, B., Mrowietz, U., et al. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.11.024 · Cited by 84

Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus

Yang, J. Y., Yang, X., Zou, H., & Li, M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/2526174 · Cited by 89

Third trimester phthalate exposure is associated with DNA methylation of growth-related genes in human placenta

Zhao, Y., Chen, J., Wang, X., Song, Q., Xu, H., & Zhang, Y. (2016) · Scientific Reports · doi:10.1038/srep33449 · Cited by 83

Amino acid metabolism as drug target in autoimmune diseases

Mondanelli, G., Iacono, A., Carvalho, A., Orabona, C., Volpi, C., Pallotta, M. T., Matino, D., Esposito, S., & Grohmann, U. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.02.004 · Cited by 84

Environmental Immunology: Lessons Learned from Exposure to a Select Panel of Immunotoxicants

Kreitinger, J. M., Beamer, C. A., & Shepherd, D. M. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502149 · Cited by 88

How the AHR Became Important in Intestinal Homeostasis—A Diurnal FICZ/AHR/CYP1A1 Feedback Controls Both Immunity and Immunopathology

Rannug, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165681 · Cited by 83

Aryl hydrocarbon receptor (AHR) functions: Balancing opposing processes including inflammatory reactions

Bock, K. W. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114093 · Cited by 84

Intestinal microbial metabolites in human metabolism and type 2 diabetes

Herrema, H., & Niess, J. H. (2020) · Diabetologia · doi:10.1007/s00125-020-05268-4 · Cited by 83

Tryptophan Feeding of the IDO1-AhR Axis in Host–Microbial Symbiosis

Zelante, T., Iannitti, R. G., Fallarino, F., Gargaro, M., LUCA, A. D., Moretti, S., Bartoli, A., & Romani, L. R. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00640 · Cited by 79

Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health

Sivaprakasam, S., Bhutia, Y. D., Ramachandran, S., & Ganapathy, V. (2017) · Nutrients · doi:10.3390/nu9080856 · Cited by 79

Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

Gargaro, M., Vacca, C., Massari, S., Scalisi, G., Manni, G., Mondanelli, G., Mazza, E. M. C., Bicciato, S., Pallotta, M. T., Orabona, C., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01973 · Cited by 79

Ahr-Foxp3-RORγt axis controls gut homing of CD4 + T cells by regulating GPR15

Xiong, L., Dean, J. W., Fu, Z., Oliff, K. N., Bostick, J. W., Ye, J., Chen, Z. E., Mühlbauer, M., & Zhou, L. (2020) · Science Immunology · doi:10.1126/sciimmunol.aaz7277 · Cited by 76

Regulation of Innate Lymphoid Cells by Aryl Hydrocarbon Receptor

Li, S., Bostick, J. W., & Zhou, L. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01909 · Cited by 81

A dysbiotic microbiome promotes head and neck squamous cell carcinoma

Frank, D. N., Qiu, Y., Cao, Y. Q., Zhang, S., Lu, L., Kofonow, J. M., Robertson, C. E., Liu, Y., Wang, H., Levens, C. L., et al. (2022) · Oncogene · doi:10.1038/s41388-021-02137-1 · Cited by 81

Clostridium sporogenes -derived metabolites protect mice against colonic inflammation

Krause, F. F., Mangold, K., Ruppert, A.-L., Leister, H., Hellhund, A., Krol, A. L., Pesek, J., Watzer, B., Winterberg, S., Raifer, H., et al. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2412669 · Cited by 79

Environmental Endocrine Disruptors and Endometriosis

Rumph, J. T., Stephens, V. R., Archibong, A. E., Osteen, K. G., & Bruner‐Tran, K. L. (2020) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-030-51856-1_4 · Cited by 74

Microbiota Metabolite Regulation of Host Immune Homeostasis: A Mechanistic Missing Link

Steinmeyer, S. H., Lee, K., Jayaraman, A., & Alaniz, R. C. (2015) · Current Allergy and Asthma Reports · doi:10.1007/s11882-015-0524-2 · Cited by 73

Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

Pandey, S. P., Bender, M. J., McPherson, A. C., Phelps, C. M., Sanchez, L. M., Rana, M., Hedden, L., Sangani, K. A., Chen, L., Shapira, J. H., et al. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.05.006 · Cited by 72

AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome:” a translational review and therapeutic perspectives

Turski, W. A., Wnorowski, A., Turski, G. N., Turski, C. A., & Turski, L. (2020) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-201042 · Cited by 73

The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation

Kenison, J. E., Wang, Z., Yang, K., Snyder, M., Quintana, F. J., & Sherr, D. H. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012692118 · Cited by 72

Aryl hydrocarbon receptor (AHR)-mediated inflammation and resolution: Non-genomic and genomic signaling

Bock, K. W. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114220 · Cited by 73

AHR is a master regulator of diverse pathways in endogenous metabolism

Granados, J. C., Falah, K., Koo, I., Morgan, E. W., Perdew, G. H., Patterson, A. D., Jamshidi, N., & Nigám, S. K. (2022) · Scientific Reports · doi:10.1038/s41598-022-20572-2 · Cited by 78

Modulation of Immune Responses by Nutritional Ligands of Aryl Hydrocarbon Receptor

de Juan, A., & Segura, É. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.645168 · Cited by 71

The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice

Diny, N. L., Schonfeldova, B., Shapiro, M., Winder, M. L., Varsani-Brown, S., & Stockinger, B. (2022) · The Journal of Experimental Medicine · doi:10.1084/jem.20210970 · Cited by 71

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity

Gomez, A. V., Bindesbøll, C., Satheesh, S. V., Grimaldi, G., Hutin, D., MacPherson, L., Ahmed, S., Tamblyn, L., Cho, T., Nebb, H. I., et al. (2018) · Biochemical Journal · doi:10.1042/bcj20180347 · Cited by 69

Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight

Burris, H. H., Baccarelli, A., Byun, H., Cantoral, A., Just, A. C., Pantic, I., Solano-González, M., Svensson, K., Tamayo‐Ortiz, M., Zhao, Y., et al. (2015) · Epigenetics · doi:10.1080/15592294.2015.1078963 · Cited by 70

Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation

Pinto, C. J. G., Ávila‐Gálvez, M. Á., Lian, Y., Moura‐Alves, P., & dos Santos, C. N. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102622 · Cited by 73

An integrative data mining approach to identifying adverse outcome pathway signatures

Oki, N. O., & Edwards, S. W. (2016) · Toxicology · doi:10.1016/j.tox.2016.04.004 · Cited by 68

The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs

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Indoxyl sulfate–induced TNF‐α is regulated by crosstalk between the aryl hydrocarbon receptor, NF‐κB, and SOCS2 in human macrophages

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