The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Cell Culture Models in Microfluidic Systems
Abstract
Microfluidic technology holds great promise for the creation of advanced cell culture models. In this review, we discuss the characterization of cell culture in microfluidic systems, describe important biochemical and physical features of the cell microenvironment, and review studies of microfluidic cell manipulation in the context of these features. Finally, we consider the integration of analytical elements, ways to achieve high throughput, and the design constraints imposed by cell biology applications.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382
Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Regulation of angiogenesis by hypoxia: role of the HIF system
Pugh, C. W., & Ratcliffe, P. J. (2003) · Nature Medicine · doi:10.1038/nm0603-677 · Cited by 2,520
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells
Anderson, D. G., Levenberg, S., & Langer, R. (2004) · Nature Biotechnology · doi:10.1038/nbt981 · Cited by 747
Observations of the living developing nerve fiber
Harrison, R. G., Greenman, M. J., Mall, F. P., & Jackson, C. M. (1907) · The Anatomical Record · doi:10.1002/ar.1090010503 · Cited by 515 · cited 1×
“Although our understanding of molecular and cell biology has increased tremendously over the past 100 years, the methods used today are surprisingly similar to those employed by Harrison in his 1907 study of frog neurons cultured in hanging drops of clotted frog lymph on a depression slide (1).”
MethodA novel 3D mammalian cell perfusion-culture system in microfluidic channels
Toh, Y.-C., Zhang, C., Zhang, J., Khong, Y. M., Chang, S., Samper, V. D., van Noort, D., Hutmacher, D. W., & Yu, H. (2007) · Lab on a Chip · doi:10.1039/b614872g · Cited by 414
A microfluidic platform for 3-dimensional cell culture and cell-based assays
Kim, M. S., Yeon, J. H., & Park, J.-K. (2007) · Biomedical Microdevices · doi:10.1007/s10544-006-9016-4 · Cited by 166
Cited by
Reconstituting organ-level lung functions on a chip
Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250
From 3D cell culture to organs-on-chips
Huh, D., Hamilton, G. A., & Ingber, D. E. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.09.005 · Cited by 1,834
A guide to the organ-on-a-chip
Leung, C. M., de Haan, P., Ronaldson-Bouchard, K., Kim, G.-A., Ko, J., Rho, H. S., Chen, Z., Habibovic, P., Jeon, N. L., Takayama, S., et al. (2022) · Nature Reviews Methods Primers · doi:10.1038/s43586-022-00118-6 · Cited by 1,116
Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
Halldorsson, S., Lucumi, E., Gómez-Sjöberg, R., & Fleming, R. M. T. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.07.029 · Cited by 1,027
Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics
Friend, J., & Yeo, L. Y. (2011) · Reviews of Modern Physics · doi:10.1103/revmodphys.83.647 · Cited by 964
Metadata
- Authors
- Meyvantsson, I., & Beebe, D. J.
- Venue
- Annual Review of Analytical Chemistry
- Publisher
- Annual Reviews
- Published
- 2008-07-01
- Volume
- 1
- Issue
- 1
- Pages
- 423-449
- ISSN
- 1936-1327 (ISSN-L)
- 1936-1335
- OpenAlex
- W2160322193
- Cited by
- 345
- References
- 8
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- Meyvantsson, I., & Beebe, D. J. (2008). Cell Culture Models in Microfluidic Systems. Annual Review of Analytical Chemistry. https://doi.org/10.1146/annurev.anchem.1.031207.113042
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
