Fat and Beyond: The Diverse Biology of PPARγ

Obesity is associated with macrophage accumulation in adipose tissue

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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The hormone resistin links obesity to diabetes

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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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Inflammation, stress, and diabetes

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

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An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

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The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity

Cho, Y. M., Kim, D. H., Lee, K. H., Jeong, S., & Kwon, O. (2018) · Experimental & Molecular Medicine · doi:10.1038/s12276-018-0131-0 · Cited by 28

Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth

Pich-Bavastro, C., Meylan, P., Mastelic-Gavillet, B., Nguyễn, T. N., Loyon, R., Trang, B. K., Moser, H., Moret, C., Goepfert, C., Hafner, J., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-0912 · Cited by 27

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity

Yanagida, K., Igarashi, H., Yasuda, D., Kobayashi, D., Ohto‐Nakanishi, T., Akahoshi, N., Sekiba, A., Toyoda, T., Ishijima, T., Nakai, Y., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.97293 · Cited by 28

RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes

Jeon, Y. G., Lee, J. H., Ji, Y., Sohn, J. H., Lee, D., Kim, D. W., Yoon, S. G., Shin, K. C., Park, J., Seong, J. K., et al. (2019) · Diabetes · doi:10.2337/db19-0508 · Cited by 28

Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development

Vernochet, C., Peres, S. B., & Farmer, S. R. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07302.x · Cited by 28

Decreased PPARγ Expression Compromises Perigonadal-Specific Fat Deposition and Insulin Sensitivity

Tsai, Y.-S., Tsai, P.-J., Jiang, M.-J., Chou, T.-Y., Pendse, A. A., Kim, H., & Maeda, N. (2009) · Molecular Endocrinology · doi:10.1210/me.2009-0073 · Cited by 28

Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes

Moon, M., Jeong, J., Lee, Y.-J., Seol, J., & Park, S. (2014) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2014.1856 · Cited by 28

Therapeutic Targeting of PPARγ in Nonalcoholic Fatty Liver Disease: Efficacy, Safety, and Drug Development

Zhou, Z., Jin, R., Gu, Y., Ji, Y., Lou, Y., & Wu, J. (2025) · Drug Design Development and Therapy · doi:10.2147/dddt.s524893 · Cited by 29

Blocking the Peroxisome Proliferator‐Activated Receptor (PPAR): An Overview

Ammazzalorso, A., Filippis, B. D., Giampietro, L., & Amoroso, R. (2013) · ChemMedChem · doi:10.1002/cmdc.201300250 · Cited by 27

Sweet and Sour - Oxidative and Carbonyl Stress in Neurological Disorders

Harris, R. A., & Amor, S. (2011) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152711794488656 · Cited by 27

Improved insulin sensitivity after treatment with PPARγ and PPARα ligands is mediated by genetically modulated transcripts

Rasouli, N., Kern, P. A., Elbein, S. C., Sharma, N., & Das, S. K. (2012) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e328352a72e · Cited by 27

Suppression of Very Early Stage Of Adipogenesis by Baicalein, a Plant-Derived Flavonoid through Reduced Akt-C/EBPα-GLUT4 Signaling-Mediated Glucose Uptake in 3T3-L1 Adipocytes

Nakao, Y., Hideto, Y., & Fujimori, K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163640 · Cited by 27

Relationship of PPARG, PPARGC1A, and PPARGC1B polymorphisms with susceptibility to hepatocellular carcinoma in an eastern Chinese Han population

Zhang, S., Jiang, J., Chen, Z., Wang, Y., Tang, W., Chen, Y., & Liu, L. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s168274 · Cited by 27

Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice

Shin, S.-K., Cho, H.-W., Song, S.-E., Bae, J., Im, S., Hwang, I., Ha, H., & Song, D. (2019) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-018-02250-3 · Cited by 27

Current Research Approaches and Challenges in the Obesogen Field

Chamorro-García, R., & Blumberg, B. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00167 · Cited by 27

The Concept of Pathogenic TH2 Cells: Collegium Internationale Allergologicum Update 2021

Bertschi, N., Bazzini, C., & Schlapbach, C. (2021) · International Archives of Allergy and Immunology · doi:10.1159/000515144 · Cited by 26

Sphingosine‐1‐phosphate in mitochondrial function and metabolic diseases

Duan, M., Gao, P., Chen, S., Novák, P., Yin, K., & Zhu, X. (2022) · Obesity Reviews · doi:10.1111/obr.13426 · Cited by 29

Geranylgeranyl pyrophosphate stimulates PPARγ expression and adipogenesis through the inhibition of osteoblast differentiation

Weivoda, M. M., & Hohl, R. J. (2011) · Bone · doi:10.1016/j.bone.2011.09.056 · Cited by 27

PPARγand PPARGC1B polymorphisms modify the association between phthalate metabolites and breast cancer risk

Martínez‐Nava, G. A., Burguete-García, A. I., López‐Carrillo, L., Hernández‐Ramírez, R. U., Madrid‐Marina, V., & Cebrián, M. E. (2013) · Biomarkers · doi:10.3109/1354750x.2013.816776 · Cited by 27

Specific Unsaturated Fatty Acids Enforce the Transdifferentiation of Human Cancer Cells toward Adipocyte-like Cells

Ruiz‐Vela, A., Aguilar-Gallardo, C., Martínez-Arroyo, A. M., Soriano‐Navarro, M., Ruiz, V., & Simón, C. (2011) · Stem Cell Reviews and Reports · doi:10.1007/s12015-011-9253-7 · Cited by 27

Role of physiological levels of 4-hydroxynonenal on adipocyte biology: implications for obesity and metabolic syndrome

Dasuri, K., Ebenezer, P. J., Fernandez‐Kim, S. O., Zhang, L., Gao, Z., Bruce‐Keller, A. J., Freeman, L. R., & Keller, J. N. (2012) · Free Radical Research · doi:10.3109/10715762.2012.733003 · Cited by 27

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes

Zheng, W., Feng, X., Qiu, L., Pan, Z., Wang, R., Lin, S., Hou, D., Jin, L., & Li, Y. (2012) · Diabetologia · doi:10.1007/s00125-012-2777-9 · Cited by 27

The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation

Kilroy, G. E., Carter, L. E., Newman, S. S., Burk, D. H., Manuel, J., Möller, A., Bowtell, D. D. L., Mynatt, R. L., Ghosh, S., & Floyd, Z. E. (2015) · Obesity · doi:10.1002/oby.21220 · Cited by 25

Reduced PPARγ2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modifications

Lecoutre, S., Pourpe, C., Butruille, L., Marousez, L., Laborie, C., Guinez, C., Lésage, J., Vieau, D., Eeckhoute, J., Gabory, A., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201700997r · Cited by 27

Multi-omics Analysis Reveals Adipose–tumor Crosstalk in Patients with Colorectal Cancer

Holowatyj, A. N., Haffa, M., Lin, T., Scherer, D., Gigic, B., Ose, J., Warby, C. A., Himbert, C., Abbenhardt, C., Achaintre, D., et al. (2020) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-19-0538 · Cited by 24

Good or bad: Paradox of plasminogen activator inhibitor 1 (PAI-1) in digestive system tumors

Wang, B., Gu, B., Zhang, T., Li, X., Wang, N., Ma, C., Xiang, L., Wang, Y., Gao, L., Yu, Y., et al. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216117 · Cited by 26

ACSS2 controls PPARγ activity homeostasis to potentiate adipose-tissue plasticity

Chen, N., Zhao, M., Wu, N., Guo, Y., Cao, B., Zhan, B., Li, Y., Zhou, T., Zhu, F., Guo, C. H., et al. (2024) · Cell Death and Differentiation · doi:10.1038/s41418-024-01262-0 · Cited by 29

Epigenetic and Genotoxic Mechanisms of PFAS-Induced Neurotoxicity: A Molecular and Transgenerational Perspective

Kebieche, N., Yim, S., Lambert, C., & Soulimani, R. (2025) · Toxics · doi:10.3390/toxics13080629 · Cited by 29

The PVH as a Site of CB1-Mediated Stimulation of Thermogenesis by MC4R Agonism in Male Rats

Monge-Roffarello, B., Labbé, S. M., Roy, M.-C., Lemay, M.-L., Coneggo, E., Samson, P., Lanfray, D., & Richard, D. (2014) · Endocrinology · doi:10.1210/en.2013-2092 · Cited by 26

Activation of PPARγ by rosiglitazone attenuates intestinal Cl−secretion

Bajwa, P. J., Lee, J. W., Straus, D. S., & Lytle, C. Y. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.90640.2008 · Cited by 26

Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity

Peña, L., Meana, C., Astudillo, A. M., Lordén, G., Valdearcos, M., Sato, H., Murakami, M., Balsinde, J., & Balboa, M. A. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.06.004 · Cited by 26

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

Göbel, T., Diehl, O., Heering, J., Merk, D., Angioni, C., Wittmann, S. K., la Buscató, E., Kottke, R., Weizel, L., Schader, T., et al. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00263 · Cited by 26

Effects of Three Thiazolidinediones on Metabolic Regulation and Cold-Induced Thermogenesis.

Sohn, J. H., Kim, J. I., Jeon, Y. G., Park, J., & Kim, J. B. (2018) · Europe PMC (PubMed Central) · doi:10.14348/molcells.2018.0294 · Cited by 26

Ameliorative effect of combined low dose of Pioglitazone and omega‐3 on spermatogenesis and steroidogenesis in diabetic rats

Hasan, M. M., El‐Shal, A. S., Mackawy, A. M. H., Ibrahim, E. M., Abdelghany, E. M. A., Saeed, A. A., & El‐Gendy, J. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29388 · Cited by 26

Antibiotics promote abdominal fat accumulation in broilers

Li, D., Zhang, K., Pan, Z., Yu, M., Lu, Y., Wang, G., Wu, J., Zhang, J., Zhang, K., & Du, W. (2020) · Animal Science Journal · doi:10.1111/asj.13326 · Cited by 26

Dysregulated H3K27 Acetylation Is Implicated in Fatty Liver Hemorrhagic Syndrome in Chickens

Zhu, Y., Zeng, Q., Li, F., Fang, H., Zhou, Z., Jiang, T., Yin, C., Wei, Q., Wang, Y., Ruan, J., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2020.574167 · Cited by 26

Tributyltin and high‐refined carbohydrate diet lead to metabolic and reproductive abnormalities, exacerbating premature ovary failure features in the female rats

Zanol, J. F., Niño, O. M. S., da Costa, C. S., Freitas‐Lima, L. C., Miranda‐Alves, L., & Graceli, J. B. (2021) · Reproductive Toxicology · doi:10.1016/j.reprotox.2021.06.004 · Cited by 26

Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet

Kan, S., Li, R., Tan, Y., Yang, F., Xu, S., Wang, L., Zhang, L., Sun, X., Chen, X., Yang, Y., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04636-9 · Cited by 26

Epigenetic landscape in PPARγ2 in the enhancement of adipogenesis of mouse osteoporotic bone marrow stromal cell

Zhang, Y., Ma, C., Liu, X., Wu, Z., Yan, P., Ma, N., Fan, Q., & Zhao, Q. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.08.020 · Cited by 26

Protective Effects of Turbinaria ornata and Padina pavonia against Azoxymethane-Induced Colon Carcinogenesis through Modulation of PPAR Gamma, NF-κB and Oxidative Stress

Mahmoud, A. M., Abdella, E. M., El-Derby, A. M., & Abd‐Ella, E. M. (2015) · Phytotherapy Research · doi:10.1002/ptr.5310 · Cited by 26

Angiotensin II Type 1 Receptor Blocker Telmisartan Reduces Cerebral Infarct Volume and Peri-infarct Cytosolic Phospholipase A 2 Level in Experimental Stroke

Kobayashi, T., Kawamata, T., Shibata, N., Okada, Y., Kobayashi, M., & Hori, T. (2009) · Journal of Neurotrauma · doi:10.1089/neu.2009.0965 · Cited by 26

Tributyltin affects adipogenic cell fate commitment in mesenchymal stem cells by a PPARγ independent mechanism

Biemann, R., Fischer, B., Blüher, M., & Santos, A. N. (2014) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2014.01.021 · Cited by 26

Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor γ Activity and on Glucose Uptake by Thiazolidinediones

Lee, K. W., Ku, Y. H., Kim, M., Ahn, B. Y., Chung, S. S., & Park, K. S. (2011) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2011.35.4.340 · Cited by 26

Lipid profile and plasma antioxidant status in sweet carbonated beverage-induced metabolic syndrome in rat

Losada, M. E. O., Grana, D. R., Müller, A., Ottaviano, G., Ambrosio, G., & Milei, J. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.09.066 · Cited by 26

Estrogen related receptor α-induced adipogenesis is PGC-1β-dependent

Ju, D., He, J., Zhao, L., Zheng, X., & Yang, G. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-1104-8 · Cited by 26

The anti-inflammatory effect of a pomegranate husk extract on inflamed adipocytes and macrophages cultivated independently, but not on the inflammatory vicious cycle between adipocytes and macrophages

Winand, J., & Schneider, Y. (2013) · Food & Function · doi:10.1039/c3fo60443h · Cited by 26

Ligand-Dependent and -Independent Regulation of PPARγ and Orphan Nuclear Receptors

Xu, H. E., & Li, Y. (2008) · Science Signaling · doi:10.1126/scisignal.148pe52 · Cited by 26

New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile

Obermoser, V., Urban, M. E., Murgueitio, M. S., Wolber, G., Kintscher, U., & Gust, R. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.08.027 · Cited by 26

Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction

Duszka, K., Picard, A., Ellero‐Simatos, S., Chen, J., Defernez, M., Paramalingam, E., Pigram, A., Vanoaica, L., Canlet, C., Parini, P., et al. (2016) · Scientific Reports · doi:10.1038/srep36937 · Cited by 28

Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties

Filho, H. V. R., Videira, N. B., Bridi, A. V., Tittanegro, T., Batista, F. A. H., Pereira, J. G. D. C., de Oliveira, P. S. L., Bajgelman, M. C., le Maire, A., & Figueira, A. C. M. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00011 · Cited by 26

Nr4a1 Is Required for Fasting-Induced Down-Regulation of Pparγ2 in White Adipose Tissue

Duszka, K., Bogner‐Strauß, J. G., Hackl, H., Rieder, D., Neuhold, C., Prokesch, A., Trajanoski, Z., & Krogsdam, A. (2012) · Molecular Endocrinology · doi:10.1210/me.2012-1248 · Cited by 27

Organization of nuclear architecture during adipocyte differentiation

Charó, N. L., Ceschan, M. I. R., Galigniana, N. M., Toneatto, J., & Piwien‐Pilipuk, G. (2016) · Nucleus · doi:10.1080/19491034.2016.1197442 · Cited by 27

Effects of type 5-phosphodiesterase inhibition on energy metabolism and mitochondrial biogenesis in human adipose tissue ex vivo

De Toni, L., Strapazzon, G., Gianesello, L., Caretta, N., Pilon, C., Bruttocao, A., & Foresta, C. (2011) · Journal of Endocrinological Investigation · doi:10.1007/bf03346724 · Cited by 25

Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB

Zhou, Y., Xiong, X., Cheng, Z., Chen, Z., Wu, S., Yu, Y., Liu, Y., Chen, G., & Li, L. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s481769 · Cited by 25

Grape seed procyanidin extract inhibits adipogenesis and stimulates lipolysis of porcine adipocytes in vitro1

Wei, S., Zheng, Y., Zhang, M., Zheng, H., & Yan, P. (2018) · Journal of Animal Science · doi:10.1093/jas/sky158 · Cited by 25

Comparative analysis of fecal metabolite profiles in HFD-induced obese mice after oral administration of huangjinya green tea extract

Li, M., Xu, J., Zhang, Y., Chu, S., Sun, S., Huo, Y., Zhao, J., Hu, X., Wan, C. C., & Li, L. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111744 · Cited by 25

Pharmacological Approaches Using Diabetic Drugs Repurposed for Alzheimer’s Disease

Adem, M. A., Decourt, B., & Sabbagh, M. N. (2024) · Biomedicines · doi:10.3390/biomedicines12010099 · Cited by 30

The influence of maternal energy status during mid-gestation on beef offspring tenderness, muscle characteristics, and gene expression

Mohrhauser, D. A., Taylor, A. R., Gonda, M., Underwood, K. R., Pritchard, R. H., Wertz-Lutz, A. E., & Blair, A. D. (2015) · Meat Science · doi:10.1016/j.meatsci.2015.07.017 · Cited by 25

Coordinated and Interactive Expression of Genes of Lipid Metabolism and Inflammation in Adipose Tissue and Liver during Metabolic Overload

Liang, W., Tonini, G., Mulder, P., Kelder, T., van Erk, M., van den Hoek, A. M., Mariman, R., Wielinga, P. Y., Baccini, M., Kooistra, T., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075290 · Cited by 25

Seeking the source of adipocytes in adult white adipose tissues

Lee, Y., & Granneman, J. G. (2012) · Adipocyte · doi:10.4161/adip.20804 · Cited by 28

Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice

Kim, M. K., Yang, S., Lee, K. H., Um, J., Liu, M., Kang, H., Park, S. J., & Chung, J. H. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00092.2011 · Cited by 27

Peroxisome Proliferator–activated Receptor Gamma in the Colon

Speca, S., Dubuquoy, L., & Desreumaux, P. (2014) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000253 · Cited by 25

Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism

Zhang, P., Li, L., Bao, Z., & Huang, F. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0090-1 · Cited by 29

Relationship between the Balance of Hypertrophic/Hyperplastic Adipose Tissue Expansion and the Metabolic Profile in a High Glucocorticoids Model

Zubiría, M. G., Alzamendi, A., Moreno, G., Portales, A. E., Castrogiovanni, D. C., Spinedi, E., & Giovambattista, A. (2016) · Nutrients · doi:10.3390/nu8070410 · Cited by 24

Transcriptome-Wide Analysis Reveals the Role of PPAR γ Controlling the Lipid Metabolism in Goat Mammary Epithelial Cells

Shi, H., Zhao, W., Zhang, C., Shahzad, K., Luo, J., & Loor, J. J. (2016) · PPAR Research · doi:10.1155/2016/9195680 · Cited by 26

Atorvastatin alleviates renal ischemia-reperfusion injury in rats by promoting M1-M2 transition

Wang, Q., Su, Y., Li, Y., Zhang, Y., Yang, S., Wang, J., & Li, H. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.6074 · Cited by 25

PPARγ is dispensable for clear cell renal cell carcinoma progression

Sanchez, D. J., Steger, D. J., Skuli, N., Bansal, A., & Simon, M. C. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.05.013 · Cited by 26

The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARγ in Adipogenesis: An in Vitro Study

Hall, J. M., Powell, H. R., Rajic, L., & Korach, K. S. (2019) · Environmental Health Perspectives · doi:10.1289/ehp3444 · Cited by 28

Dual soluble epoxide hydrolase inhibitor/PPAR-γ agonist attenuates renal fibrosis

Stavniichuk, A., Khan, A. H., Yeboah, M. M., Chesnik, M. A., Jankiewicz, W. K., Hartmann, M., Blöcher, R., Kircher, T., Savchuk, О., Proschak, E., et al. (2020) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2020.106472 · Cited by 25

Peroxisome Proliferator-Activated Receptor γ Decouples Fatty Acid Uptake from Lipid Inhibition of Insulin Signaling in Skeletal Muscle

Hu, S., Yao, J., Howe, A. A., Menke, B. M., Sivitz, W. I., Spector, A. A., & Norris, A. W. (2012) · Molecular Endocrinology · doi:10.1210/me.2011-1253 · Cited by 25

Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells

Cabrera-Reyes, F., Parra-Ruiz, C., Yuseff, M. I., & Zanlungo, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.790568 · Cited by 24

Interaction ofVeratrum nigrumwithPanax ginsengagainst Obesity: A Sang-ban Relationship

Park, J., Jeon, Y., Kim, H.-L., Lim, H., Jung, Y., Youn, D., Jeong, M., Kim, H., Kim, S., Kim, S., et al. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/732126 · Cited by 24

Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARγ and Fatty Acid Uptake

Labrie, M., Lalonde, S., Najyb, O., Thiery, M., Daneault, C., Rosiers, C. D., Rassart, É., & Mounier, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0130230 · Cited by 26

The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users

Jones, J. D., Sullivan, M. A., Manubay, J. M., Mogali, S., Metz, V. E., Ciccocioppo, R., & Comer, S. D. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.10.006 · Cited by 24

Cholesterol metabolites alleviate injured liver function and decrease mortality in an LPS-induced mouse model

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Injection of phosphatidylcholine and deoxycholic acid regulates gene expression of lipolysis-related factors, pro-inflammatory cytokines, and hormones on mouse fat tissue

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Pruning of the Adipocyte Peroxisome Proliferator-Activated Receptor γ Cistrome by Hematopoietic Master Regulator PU.1

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Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells

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Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency

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Identification of a natural beige adipose depot in mice

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Exploring the mechanism of PPARγ phosphorylation mediated by CDK5

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Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction

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PPARγ activation by pioglitazone does not suppress cravings for alcohol, and is associated with a risk of myopathy in treatment seeking alcohol dependent patients: a randomized controlled proof of principle study

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Comprehensive analysis and establishment of a prediction model of alternative splicing events reveal the prognostic predictor and immune microenvironment signatures in triple negative breast cancer

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Peroxisome Proliferator-Activated Receptor .GAMMA. Ligands Isolated from Adlay Seed (Coix lacryma-jobi L. var. ma-yuen STAPF.)

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Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist

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Comparison of SGLT1, SGLT2, and Dual Inhibitor Biological Activity in Treating Type 2 Diabetes Mellitus

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Long-Term Effects of Placental Growth on Overweight and Body Composition

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Peroxisome proliferator-activated receptor-γ: a versatile metabolic regulator

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The clinical significance of PPARα and γ agonism

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PPARγ in human and mouse physiology

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Contrôle du métabolisme par des ligands de PPARγ

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