Fat and Beyond: The Diverse Biology of PPARγ

Obesity is associated with macrophage accumulation in adipose tissue

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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The hormone resistin links obesity to diabetes

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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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Inflammation, stress, and diabetes

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

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An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

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Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting

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PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

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Zebrafish Embryonic Lipidomic Analysis Reveals that the Yolk Cell Is Metabolically Active in Processing Lipid

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Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics

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PPAR and Oxidative Stress: Con() Catenating NRF2 and FOXO

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Inhibiting Adipose Tissue Lipogenesis Reprograms Thermogenesis and PPARγ Activation to Decrease Diet-Induced Obesity

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PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

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Mechanisms of insulin resistance related to white, beige, and brown adipocytes

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Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

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Obesity alters pathology and treatment response in inflammatory disease

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Surface plasmon resonance technology: Recent advances, applications and experimental cases

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Cross‐Talk between PPARγand Insulin Signaling and Modulation of Insulin Sensitivity

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Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells

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Initial Quantitative Proteomic Map of 28 Mouse Tissues Using the SILAC Mouse

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Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)

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Prospective functional classification of all possible missense variants in PPARG

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Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

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Regulation of gene expression in osteoblasts

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Age‐related thymic involution: Mechanisms and functional impact

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Impact of nutrients on circadian rhythmicity

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The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts

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Review of the Structural and Dynamic Mechanisms of PPAR γ Partial Agonism

Kroker, A. J., & Bruning, J. B. (2015) · PPAR Research · doi:10.1155/2015/816856 · Cited by 231

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

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Obesogens: an emerging threat to public health

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Minireview: Pref-1: Role in Adipogenesis and Mesenchymal Cell Fate

Sul, H. S. (2009) · Molecular Endocrinology · doi:10.1210/me.2009-0160 · Cited by 218

From chronic overnutrition to insulin resistance: The role of fat-storing capacity and inflammation

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Nuclear Hormone Receptors Enable Macrophages and Dendritic Cells to Sense Their Lipid Environment and Shape Their Immune Response

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Cell-Specific Determinants of Peroxisome Proliferator-Activated Receptor γ Function in Adipocytes and Macrophages

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Signal transduction in pancreatic stellate cells

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The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders

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Adipocyte metrnl antagonizes insulin resistance through PPARγ signaling

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The endocrine disruptor mono-(2-ethylhexyl)phthalate promotes adipocyte differentiation and induces obesity in mice

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Maternal and fetal lipid metabolism under normal and gestational diabetic conditions

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Predicting Later-Life Outcomes of Early-Life Exposures

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Ligand Binding and Activation of PPAR γ by Firemaster® 550: Effects on Adipogenesis and Osteogenesis in Vitro

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Brown Adipose Tissue—A Translational Perspective

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Endocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis

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PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis

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Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner

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A role of peroxisome proliferator‐activated receptor γ in non‐alcoholic fatty liver disease

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Mammalian Sirtuins and Energy Metabolism

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PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis

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Deciphering the Roles of PPARγ in Adipocytes via Dynamic Change of Transcription Complex

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The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

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Appearance and disappearance of the mRNA signature characteristic of T reg cells in visceral adipose tissue: Age, diet, and PPARγ effects

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Docosahexaenoic acid: one molecule diverse functions

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Environmental Obesogens and Their Impact on Susceptibility to Obesity: New Mechanisms and Chemicals

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Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function

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PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue Plasticity

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Bone Loss in Diabetes: Use of Antidiabetic Thiazolidinediones and Secondary Osteoporosis

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New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease

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The adipose organ: white‐brown adipocyte plasticity and metabolic inflammation

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Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation

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The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory

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Obesity is a concern for bone health with aging

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Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis

Jiang, Y., Berry, D. C., Tang, W., & Graff, J. M. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.09.049 · Cited by 182

The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes

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Differential effects of environmental chemicals and food contaminants on adipogenesis, biomarker release and PPARγ activation

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Effects of diabetes drugs on the skeleton

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Adiponectin and energy homeostasis

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The Metabolic Requirements of Th2 Cell Differentiation

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The regulation of adipose tissue health by estrogens

Steiner, B. M., & Berry, D. C. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.889923 · Cited by 171

Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids

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Colorectal Cancer Expression of Peroxisome Proliferator-Activated Receptor γ (PPARG, PPARgamma) Is Associated With Good Prognosis

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Marrow fat metabolism is linked to the systemic energy metabolism

Lecka‐Czernik, B. (2011) · Bone · doi:10.1016/j.bone.2011.06.032 · Cited by 168

Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation

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The CD36-PPARγ Pathway in Metabolic Disorders

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Human Urothelial Cells Isolation, In Vitro Expansion and Characterization for Evaluating Bio-Engineering Potentials

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‘Metabolically healthy obesity’: Origins and implications

Denis, G. V., & Obin, M. S. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.10.004 · Cited by 176

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

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Systemic Analysis of PPARγ in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity

Gautier, E. L., Chow, A. T., Spanbroek, R., Marcelin, G., Greter, M., Jakubzick, C., Bogunovic, M., Leboeuf, M., van Rooijen, N., Habenicht, A. J. R., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200495 · Cited by 175

The Microbiota and Epigenetic Regulation of T Helper 17/Regulatory T Cells: In Search of a Balanced Immune System

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Adipose Organ Development and Remodeling

Cinti, S. (2018) · Comprehensive physiology · doi:10.1002/cphy.c170042 · Cited by 197

Effects of Age and Dysfunction on Human Meibomian Glands

Nien, C. J. (2011) · Archives of Ophthalmology · doi:10.1001/archophthalmol.2011.69 · Cited by 164

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

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The brain and brown fat

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Free radicals and male reproduction.

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Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

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Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota

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Physiological functions of peroxisome proliferator-activated receptor β

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Emerging therapeutic opportunities for skeletal restoration

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Brucella spp. Virulence Factors and Immunity

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Neurological Effects of Bisphenol A and its Analogues

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Before They Were Fat: Adipocyte Progenitors

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The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling

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Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance

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Contrôle du métabolisme par des ligands de PPARγ

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