The DOI matches its Crossref record; 261 of the 263 references it cites were found in a registry or an index.
The Glial Nature of Embryonic and Adult Neural Stem Cells
Open accessAbstract
Glial cells were long considered end products of neural differentiation, specialized supportive cells with an origin very different from that of neurons. New studies have shown that some glial cells—radial glia (RG) in development and specific subpopulations of astrocytes in adult mammals—function as primary progenitors or neural stem cells (NSCs). This is a fundamental departure from classical views separating neuronal and glial lineages early in development. Direct visualization of the behavior of NSCs and lineage-tracing studies reveal how neuronal lineages emerge. In development and in the adult brain, many neurons and glial cells are not the direct progeny of NSCs, but instead originate from transit amplifying, or intermediate, progenitor cells (IPCs). Within NSCs and IPCs, genetic programs unfold for generating the extraordinary diversity of cell types in the central nervous system. The timing in development and location of NSCs, a property tightly linked to their neuroepithelial origin, appear to be the key determinants of the types of neurons generated. Identification of NSCs and IPCs is critical to understand brain development and adult neurogenesis and to develop new strategies for brain repair.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“GFAP is also expressed by progenitor cells15 and its expression depends on developmental stages16,17.”
From Reactive astrocyte nomenclature, definitions, and future directions (2021) · cites this paper as [15]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“In particular, and by taking advantage of Btg2 and Tubb3 expression, our group has generated a combinatorial, double-reporter mouse line in which RFP and or GFP expression allowed the isolation specifically of PP, DP and N based on their endogenous fluorescence (RFP-, RFP+ and GFP+, respectively) (31).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Unsurprisingly, when analyzing the expression pattern of the host genes of switch miRNAs (data retrieved from ( 31)), we found a high degree of overlap in their differential expression within different cell populations (Figure 3).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Experimental — accuracy not yet measuredIn the citing paper
“There is evidence of neurogenesis from adult neural stem cells deriving from the subventricular zone (SVZ) and the subgranular zone (SGZ) of the hippocampal dentate gyrus, that can give rise to neurons, oligodendrocytes and astrocytes [107,108].”
From Ageing, Cellular Senescence and Neurodegenerative Disease (2018) · cites this paper as [108]
In the citing paper
“The predicted progenitors expressed proliferation (Mki67) and known markers (Pax6, Rspo2/3, Wnt5a/3a/1, Fabp7, clusters 7 and 8 in Figure 2A,B S2B; STAR Methods), previously reported for precursors of ependymal cells and cortical neurons (Kriegstein and Alvarez-Buylla, 2009), with Wnt1 having the most specific expression (Figure S2G).”
From A cellular and spatial map of the choroid plexus across brain ventricles and ages (2021) · cites this paper as Kriegstein and Alvarez-Buylla, 2009
In the citing paper
“In embryos, subsets of glial cells expressed markers of neural progenitor/stem-like cells (e.g. Pax6, Nes, Sox2, Rspo2/3) or of oligodendrocyte precursor cells (OPCs, e.g. Olig1, Olig2) (Kriegstein and Alvarez-Buylla, 2009) (Figure 2A, S2A,B).”
From A cellular and spatial map of the choroid plexus across brain ventricles and ages (2021) · cites this paper as Kriegstein and Alvarez-Buylla, 2009
In the citing paper
“Validation and use of this mouse line revealed to be very powerful in the identification of several new genes and biological processes regulating cortical development (31).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
In the citing paper
“our group previously concluded that a transient up-or down-regulation specifically in DP compared to both their PP progenitors and N progeny (on-and off-switch transcripts, respectively) represented a hallmark of functional commitment to the neurogenic lineage (31,36).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Neurogenesis in the adult human hippocampus
Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369
Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 4,786
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,586
Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127 · cited 1×
“Astrocytes may retain fundamental properties and positional information linked to the original array of RG in the developing brain (Rakic 1988).”
BackgroundMechanisms and Functional Implications of Adult Neurogenesis
Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007
Running enhances neurogenesis, learning, and long-term potentiation in mice
van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426
Research works printed but not linked: 7
- 10.1016/S0092-8674(00)80783-7 · DOI · Paper page
- Hajós F, 1981, Acta Morphol. Acad. Sci. Hung., 29, 361
- Magini J, 1888, Arch. Ital. Biol., 10, 384
- Miyata T, 2008, Dev. Growth Differ., 50, S105
- Retzius G, 1894, Biol. Unters., 6, 1
- Smart IH, 1973, J. Anat., 116, 67
- 10.1523/JNEUROSCI.18-20-08331.1998 · DOI
Cited by
Sorted by citations
Items 601–700 of 1,011
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
Laddach, A., Chng, S. H., Lasrado, R., Progatzky, F., Shapiro, M., Erickson, A. G., Castañeda, M. S., Artemov, A. V., Bon‐Frauches, A. C., Amaniti, E.-M., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41492-3 · Cited by 54
Li, X., Sun, C., Lin, C., Ma, T., Madhavan, M., Campbell, K., & Yang, Z. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0939-11.2011 · Cited by 55
Sonic hedgehog promotes generation and maintenance of human forebrain Olig2 progenitors
Ortega, J. A., Radonjić, N. V., & Zečević, N. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00254 · Cited by 53
Adult pituitary progenitors/stem cells: from in vitro characterization to in vivo function
Rizzoti, K. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07524.x · Cited by 53
Valente, M. M., Bortolotto, V., Cuccurazzu, B., Ubezio, F., Meneghini, V., Francese, M. T., Canonico, P. L., & Grilli, M. (2012) · Molecular Pharmacology · doi:10.1124/mol.112.077636 · Cited by 53
You, L., Yan, K., Zhou, J., Hong, Z., Bertos, N., Park, M., Wang, E., & Yang, X. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005034 · Cited by 53
Doxycycline increases neurogenesis and reduces microglia in the adult hippocampus
Sultan, S., Gebara, E., & Toni, N. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00131 · Cited by 53
Adult Neurogenesis in Mammals: Variations and Confusions
Lipp, H., & Bonfanti, L. (2016) · Brain Behavior and Evolution · doi:10.1159/000446905 · Cited by 54
Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation
Tsuyama, T., Tsubouchi, A., Usui, T., Imamura, H., & Uemura, T. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201604065 · Cited by 54
Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier
Yulyaningsih, E., Rudenko, I. A., Valdearcos, M., Dahlén, E., Vagena, E., Chan, A. Y., Álvarez-Buylla, A., Vaisse, C., Koliwad, S. K., & Xu, A. W. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.05.060 · Cited by 53
HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development
Tang, T., Zhang, Y., Wang, Y., Cai, Z., Lu, Z., Li, L., Huang, R., Hagelkrüys, A., Matthias, P., Zhang, H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.01.007 · Cited by 54
Yin, J., Shen, Y., Si, Y., Zhang, Y., Du, J., Hu, X., Cai, M., Bao, H., & Xing, Y. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01970-7 · Cited by 53
Hoye, M. L., Calviello, L., Poff, A., Ejimogu, E., Newman, C. R., Montgomery, M. D., Ou, J., Floor, S. N., & Silver, D. L. (2022) · eLife · doi:10.7554/elife.78203 · Cited by 55
Concise Review: Fragile X Proteins in Stem Cell Maintenance and Differentiation
Li, Y., & Zhao, X. (2014) · Stem Cells · doi:10.1002/stem.1698 · Cited by 57
Kraushar, M. L., Viljetić, B., Wijeratne, H. R. S., Thompson, K., Jiao, X., Pike, J. W., Medvedeva, V. P., Groszer, M., Kiledjian, M., Hart, R. P., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0601-15.2015 · Cited by 53
D-serine increases adult hippocampal neurogenesis
Sultan, S., Gebara, E., Moullec, K., & Toni, N. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00155 · Cited by 55
Stipursky, J., Francis, D., & Gomes, F. C. A. (2012) · Developmental Neuroscience · doi:10.1159/000338108 · Cited by 52
Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis
Artegiani, B., Domingues, A. M. D. J., Alonso, S. B., Brandl, E., Massalini, S., Dahl, A., & Calegari, F. (2014) · The EMBO Journal · doi:10.15252/embj.201490061 · Cited by 53
Effects of melatonin and its analogues on neural stem cells
Chu, J., Tu, Y., Chen, J., Tan, D. X., Liu, X., & Pi, R. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.10.012 · Cited by 55
Tuoc, T., Dere, E., Radyushkin, K., Pham, L., Nguyen, H., Tonchev, A. B., Sun, G., Ronnenberg, A., Shi, Y., Staiger, J. F., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9948-5 · Cited by 53
McLean, W. J., McLean, D. T., Eatock, R. A., & Edge, A. S. B. (2016) · Development · doi:10.1242/dev.139840 · Cited by 52
Hypothalamic Neurogenesis as an Adaptive Metabolic Mechanism
Recabal, A., Caprile, T., & García, M. D. L. Á. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00190 · Cited by 52
Understanding the Role of lncRNAs in Nervous System Development
Clark, B. S., & Blackshaw, S. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-5203-3_9 · Cited by 56
Blood Exposure Causes Ventricular Zone Disruption and Glial Activation In Vitro
Castañeyra-Ruiz, L., Morales, D. M., McAllister, J. P., Brody, S. L., Isaacs, A. M., Strahle, J. M., Dahiya, S. M., & Limbrick, D. D. (2018) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nly058 · Cited by 52
Birkhoff, J. C., Huylebroeck, D., & Conidi, A. (2021) · Genes · doi:10.3390/genes12071037 · Cited by 52
Heurck, R. V., Bonnefont, J., Wojno, M., Suzuki, I., Velez-Bravo, F. D., Erkol, E., Nguyen, D. T., Herpoel, A., Bilheu, A., Beckers, S., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.10.018 · Cited by 55
Mechanisms of Neurogenesis in the Normal and Injured Adult Brain
Sawada, M., & Sawamoto, K. (2013) · The Keio Journal of Medicine · doi:10.2302/kjm.2012-0005-re · Cited by 55
mTOR signaling in neural stem cells: from basic biology to disease
Magri, L., & Galli, R. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1196-x · Cited by 52
Zhu, S., Wildonger, J., Barshow, S., Younger, S. H., Huang, Y., & Lee, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046724 · Cited by 51
Postembryonic neuronal addition in Zebrafish dorsal root ganglia is regulated by Notch signaling
McGraw, H. F., Snelson, C. D., Prendergast, A. E., Suli, A., & Raible, D. W. (2012) · Neural Development · doi:10.1186/1749-8104-7-23 · Cited by 51
Development and aging of a brain neural stem cell niche
Conover, J. C., & Todd, K. L. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.11.007 · Cited by 53
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo
Smart, A. D., Pache, R. A., Thomsen, N. D., Kortemme, T., Davis, G. W., & Wells, J. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1705064114 · Cited by 53
Treating Brain Disorders by Targeting Adult Neural Stem Cells
Bao, H., & Song, J. (2018) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.10.001 · Cited by 53
Thyroid hormone regulation of neural stem cell fate: From development to ageing
Gothié, J. M., Vancamp, P., DEMENEIX, B. A., & Remaud, S. (2019) · Acta Physiologica · doi:10.1111/apha.13316 · Cited by 54
Ahmad, S. T., Rogers, A. D., Chen, M. J., Dixit, R., Adnani, L., Frankiw, L., Lawn, S. O., Blough, M. D., Alshehri, M. M., Wu, W., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09949-6 · Cited by 52
In Vitro Models for NeurogenesisPreprint
Azari, H., & Reynolds, B. A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021279 · Cited by 54
Kang, K., Lee, D., Hong, S., Park, S., & Song, M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.398263 · Cited by 50
The interaction between microglia and neural stem/precursor cells
Su, P., Zhang, J., Zhao, F., Aschner, M., Chen, J., & Luo, W. (2014) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2014.09.005 · Cited by 50
Thumkeo, D., Shinohara, R., Watanabe, K., Takebayashi, H., Toyoda, Y., Tohyama, K., Ishizaki, T., Furuyashiki, T., & Narumiya, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025465 · Cited by 50
Pistollato, F., Canovas-Jorda, D., Zagoura, D., & Price, A. (2017) · Journal of Visualized Experiments · doi:10.3791/55702 · Cited by 50
Nuclear deterrents: Intrinsic regulators of IL-1β-induced effects on hippocampal neurogenesis
Ó’Léime, C. S., Cryan, J. F., & Nolan, Y. M. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.07.153 · Cited by 53
Krefft, O., Jabali, A., Iefremova, V., Koch, P., & Ladewig, J. (2018) · Journal of Visualized Experiments · doi:10.3791/56768 · Cited by 53
Takahashi, H., Yoshihara, S., & Tsuboi, A. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00229 · Cited by 50
Wilems, T. S., Vardhan, S., Wu, S., & Sakiyama‐Elbert, S. E. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.03.004 · Cited by 50
Neural Stem Cell Regulation by Adhesion Molecules Within the Subependymal Niche
Morante‐Redolat, J. M., & Porlan, E. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00102 · Cited by 50
Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex
Chen, P., Zhang, T., Yuan, Z., Shen, B., & Chen, L. (2019) · Molecular Brain · doi:10.1186/s13041-019-0496-6 · Cited by 50
Diversity of Neural Precursors in the Adult Mammalian BrainPreprint
Bonaguidi, M. A., Stadel, R. P., Berg, D. A., Sun, J., Ming, G., & Song, H. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018838 · Cited by 51
Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells
Baena-López, L. A., Arthurton, L., Bischoff, M., Vincent, J., Alexandre, C., & McGregor, R. (2018) · Development · doi:10.1242/dev.170811 · Cited by 49
Treating Parkinson’s disease by astrocyte reprogramming: Progress and challenges
Wei, Z. D., & Shetty, A. K. (2021) · Science Advances · doi:10.1126/sciadv.abg3198 · Cited by 50
houcke, J. V., Mariën, V., Zandecki, C., Vanhunsel, S., Moons, L., Ayana, R., Seuntjens, E., & Arckens, L. (2021) · Aging Cell · doi:10.1111/acel.13464 · Cited by 51
Progenitor Cell Dynamics in the Newt Telencephalon during Homeostasis and Neuronal Regeneration
Kirkham, M., Hameed, L. S., Berg, D. A., Wang, H., & Simon, A. (2014) · Stem Cell Reports · doi:10.1016/j.stemcr.2014.01.018 · Cited by 49
A role for Bicaudal-D2 in radial cerebellar granule cell migration
Jaarsma, D., van den Berg, R., Wulf, P. S., van Erp, S., Keijzer, N., Schlager, M. A., de Graaff, E., Zeeuw, C. I. D., Pasterkamp, R. J., Akhmanova, A. S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4411 · Cited by 49
Balasubramanian, S., Packard, J. A., Leach, J. B., & Powell, E. M. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0103 · Cited by 53
Regulation of adult neural progenitor cell functions by purinergic signaling
Tang, Y., & Illés, P. (2016) · Glia · doi:10.1002/glia.23056 · Cited by 51
Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord
Wang, L.-L., & Zhang, C. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2729-2 · Cited by 50
Nagashima, M., D’Cruz, T. S., Danku, A. E., Hesse, D., Sifuentes, C. J., Raymond, P. A., & Hitchcock, P. F. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.1675-19.2019 · Cited by 49
Kase, Y., Shimazaki, T., & Okano, H. (2020) · Inflammation and Regeneration · doi:10.1186/s41232-020-00122-x · Cited by 51
Neuronal Network Formation from Reprogrammed Early Postnatal Rat Cortical Glial Cells
Blum, R., Heinrich, C., Sánchez, R., Lepier, A., Gundelfinger, E. D., Berninger, B., & Götz, M. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq107 · Cited by 54
Braun, S. M. G., Petrova, R., Tang, J., Krokhotin, A., Miller, E. L., Tang, Y., Panagiotakos, G., & Crabtree, G. R. (2021) · Genes & Development · doi:10.1101/gad.342345.120 · Cited by 51
Kraushar, M. L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M. C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C. H., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2020.11.037 · Cited by 49
Zimmer, T. S., Broekaart, D. W. M., Gruber, V.-E., van Vliet, E. A., Mühlebner, A., & Aronica, E. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.01028 · Cited by 48
A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice
Hoffmann, N., Fernández, V., Pereira, R. C., Rancati, S., Pelizzoli, R., & Tonelli, D. D. P. (2019) · iScience · doi:10.1016/j.isci.2019.100813 · Cited by 49
Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models
Pranty-Weßelmann, A. I., Shumka, S., & Adjaye, J. (2022) · Cells · doi:10.3390/cells11172647 · Cited by 48
Neuronal polarization in vivo: Growing in a complex environment
Funahashi, Y., Namba, T., Nakamuta, S., & Kaibuchi, K. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.04.009 · Cited by 51
Kaneko, N., Kako, E., & Sawamoto, K. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00235 · Cited by 49
Role of miRNAs and epigenetics in neural stem cell fate determination
Lopez‐Ramirez, M. A., & Nicoli, S. (2013) · Epigenetics · doi:10.4161/epi.27536 · Cited by 48
Radmis, a Novel Mitotic Spindle Protein that Functions in Cell Division of Neural Progenitors
Yumoto, T., Nakadate, K., Nakamura, Y., Sugitani, Y., Yoshida-Sugitani, R., Ueda, S., & Sakakibara, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079895 · Cited by 52
Physiological roles of ion channels in adult neural stem cells and their progeny
Yasuda, T., & Adams, D. J. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06822.x · Cited by 48
UbC-StarTrack, a clonal method to target the entire progeny of individual progenitors
Figueres‐Oñate, M., García‐Marqués, J., & López‐Mascaraque, L. (2016) · Scientific Reports · doi:10.1038/srep33896 · Cited by 48
Potential mechanisms of Zika‐linked microcephaly
Merfeld, E., Ben‐Avi, L., Kennon, M., & Cerveny, K. L. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.273 · Cited by 49
Radial Glia Cells Control Angiogenesis in the Developing Cerebral Cortex Through TGF-β1 Signaling
Siqueira, M., Francis, D., Gisbert, D., Gomes, F. C. A., & Stipursky, J. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0557-8 · Cited by 48
Zhu, J., Palliyil, S., Chen, R., & Kumar, J. P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1610614114 · Cited by 51
Midbrain tectal stem cells display diverse regenerative capacities in zebrafish
Lindsey, B. W., Aitken, G., Tang, J., Khabooshan, M. A., Douek, A. M., Vandestadt, C., & Kaslin, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-40734-z · Cited by 48
Lam, M., Moslem, M., Bryois, J., Pronk, R., Uhlin, E., Ellström, I. D., Laan, L., Olive, J. F., Morse, R., Rönnholm, H., et al. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.06.014 · Cited by 50
Functional integration of “undead” neurons in the olfactory system
Prieto-Godino, L. L., Silbering, A. F., Khallaf, M. A., Cruchet, S., Bojkowska, K., Pradervand, S., Hansson, B. S., Knaden, M., & Benton, R. (2020) · Science Advances · doi:10.1126/sciadv.aaz7238 · Cited by 48
Ontogeny of adult neural stem cells in the mammalian brain
Bond, A. M., Ming, G., & Song, H. (2020) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.11.002 · Cited by 51
Bonfanti, L., & Seki, T. (2021) · Cells · doi:10.3390/cells10102542 · Cited by 54
Circuit formation and maintenance—perspectives from the mammalian olfactory bulb
Adam, Y., & Mizrahi, A. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.11.001 · Cited by 48
ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease
Tang, X., Walter, E., Wohleb, E., Fan, Y., & Wang, C. (2024) · Autophagy · doi:10.1080/15548627.2023.2277634 · Cited by 43
Gampe, K., Stefani, J., Hammer, K., Brendel, P., Pötzsch, A., Enikolopov, G., Enjyoji, K., Acker‐Palmer, A., Robson, S. C., & Zimmermann, H. (2014) · Stem Cells · doi:10.1002/stem.1846 · Cited by 48
Brain Cancer Stem Cells: Current Status on Glioblastoma Multiforme
Facchino, S., Abdouh, M., & Bernier, G. (2011) · Cancers · doi:10.3390/cancers3021777 · Cited by 47
Park, T., Monzó, H. J., Mee, E. W., Bergin, P., Teoh, H. H., Montgomery, J. M., Faull, R. L. M., Curtis, M. A., & Dragunow, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037742 · Cited by 47
NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche
Heng, Y. H. E., Zhou, B., Harris, L., Harvey, T. J., Smith, A. G., Horne, E., Martynoga, B., Andersen, J., Achimastou, A., Cato, K., et al. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu253 · Cited by 47
Zhang, S., Anderson, M. A., Ao, Y., Khakh, B. S., Fan, J. H., Deming, T. J., & Sofroniew, M. V. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.005 · Cited by 48
Lopez, C. I., Saud, K., Aguilar, R., Berndt, F. A., Cánovas, J., Montecino, M. A., & Manuel Kukuljan, P. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22397 · Cited by 47
Kim, M., Jung, K., Kim, I., Lee, I.-S., Ko, Y., Shin, J. E., & Park, K. I. (2018) · Experimental & Molecular Medicine · doi:10.1038/s12276-018-0033-1 · Cited by 47
Pitzer, E. M., Sugimoto, C., Gudelsky, G. A., Adams, C. L. H., Williams, M. T., & Vorhees, C. V. (2019) · Toxicological Sciences · doi:10.1093/toxsci/kfz067 · Cited by 47
Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects
Mei, X., Qi, D., Zhang, T., Zhao, Y., Li, J., Hou, J., Wang, J., Lin, Y., Xue, Y., Zhu, P., et al. (2020) · EMBO Molecular Medicine · doi:10.15252/emmm.201809469 · Cited by 47
Roth, J. G., Muench, K. L., Asokan, A., Mallett, V. M., Gai, H., Verma, Y., Weber, S., Charlton, C. A., Fowler, J. L., Loh, K. M., et al. (2020) · eLife · doi:10.7554/elife.58178 · Cited by 47
Neuronal fate acquisition and specification: time for a change
Bonnefont, J., & Vanderhaeghen, P. (2021) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.12.006 · Cited by 49
Diotel, N., Servili, A., Guéguen, M., Mironov, S., Pellegrini, E., Vaillant, C., Zhu, Y., Kah, O., & Anglade, I. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028375 · Cited by 46
Noguchi, H., Kimura, A., Murao, N., Matsuda, T., Namihira, M., & Nakashima, K. (2015) · Neuroscience Research · doi:10.1016/j.neures.2015.01.014 · Cited by 49
Raines, A. N., Nagdas, S., Kerber, M. L., & Cheney, R. E. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.369173 · Cited by 46
Embryonic stem cell neurogenesis and neural specification
Germain, N. D., Banda, E. C., & Grabel, L. B. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22747 · Cited by 48
Oboti, L., Ibarra-Soria, X., Pérez‐Gómez, A., Schmid, A., Pyrski, M. M., Paschek, N., Kircher, S., Logan, D. W., Leinders‐Zufall, T., Zufall, F., et al. (2015) · BMC Biology · doi:10.1186/s12915-015-0211-8 · Cited by 46
Li, J., Ma, J., Meng, G., Lin, H., Wu, S. L. Y., Wang, J., Luo, J., Xu, X., Tough, D. F., Lindon, M. J., et al. (2016) · Stem Cell Research · doi:10.1016/j.scr.2016.07.006 · Cited by 47
Magistri, M., Khoury, N., Mazza, E. M. C., Velmeshev, D., Lee, J. K., Bicciato, S., Tsoulfas, P., & Faghihi, M. A. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13382 · Cited by 46
Sild, M., Ruthazer, E. S., & Booij, L. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.09.014 · Cited by 47
Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth
Sarpal, R., Yan, V., Kazakova, L., Sheppard, L., Yu, J. C., Fernández‐González, R., & Tepaß, U. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008454 · Cited by 47
Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye
Wong, B. H., & Silver, D. L. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-6082-8_14 · Cited by 49
Metadata
- Authors
- Kriegstein, A., & Alvarez-Buylla, A.
- Affiliations
- University of California, San Francisco (US)
- The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Departments of Neurology, Neurological Surgery, and School of Medicine, University of California, San Francisco, California 94143-0525;,
- ORCID
- Kriegstein, Arnold
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2009-06-01
- Volume
- 32
- Issue
- 1
- Pages
- 149-184
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- PMC
- PMC3086722
- OpenAlex
- W2172266256
- Cited by
- 2,475
- References
- 263
- Citations by year
- 2026: 87 · 2025: 141 · 2024: 138 · 2023: 131 · 2022: 133 · 2021: 168 · 2020: 162 · 2019: 147 · 2018: 166 · 2017: 155 · 2016: 162 · 2015: 129 · 2014: 167 · 2013: 172 · 2012: 155
- FWCI
- 12.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (R01NS035710, R01NS028478, R01NS021223)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- neural stem cells, radial glia, astrocytes, intermediate progenitor cells, transit amplifying cells, neuronal lineage, neuroepithelium, adult neurogenesis, brain development, lineage tracing, brain repair
- MeSH terms
- Animals, Cell Differentiation, Central Nervous System, Humans, Neuroglia, Neurons, Stem Cells, Gene Expression Regulation, Developmental, Cell Lineage, Adult Stem Cells, Neurogenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
