The DOI matches its Crossref record; 261 of the 263 references it cites were found in a registry or an index.
The Glial Nature of Embryonic and Adult Neural Stem Cells
Open accessAbstract
Glial cells were long considered end products of neural differentiation, specialized supportive cells with an origin very different from that of neurons. New studies have shown that some glial cells—radial glia (RG) in development and specific subpopulations of astrocytes in adult mammals—function as primary progenitors or neural stem cells (NSCs). This is a fundamental departure from classical views separating neuronal and glial lineages early in development. Direct visualization of the behavior of NSCs and lineage-tracing studies reveal how neuronal lineages emerge. In development and in the adult brain, many neurons and glial cells are not the direct progeny of NSCs, but instead originate from transit amplifying, or intermediate, progenitor cells (IPCs). Within NSCs and IPCs, genetic programs unfold for generating the extraordinary diversity of cell types in the central nervous system. The timing in development and location of NSCs, a property tightly linked to their neuroepithelial origin, appear to be the key determinants of the types of neurons generated. Identification of NSCs and IPCs is critical to understand brain development and adult neurogenesis and to develop new strategies for brain repair.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“GFAP is also expressed by progenitor cells15 and its expression depends on developmental stages16,17.”
From Reactive astrocyte nomenclature, definitions, and future directions (2021) · cites this paper as [15]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“In particular, and by taking advantage of Btg2 and Tubb3 expression, our group has generated a combinatorial, double-reporter mouse line in which RFP and or GFP expression allowed the isolation specifically of PP, DP and N based on their endogenous fluorescence (RFP-, RFP+ and GFP+, respectively) (31).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Unsurprisingly, when analyzing the expression pattern of the host genes of switch miRNAs (data retrieved from ( 31)), we found a high degree of overlap in their differential expression within different cell populations (Figure 3).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Experimental — accuracy not yet measuredIn the citing paper
“There is evidence of neurogenesis from adult neural stem cells deriving from the subventricular zone (SVZ) and the subgranular zone (SGZ) of the hippocampal dentate gyrus, that can give rise to neurons, oligodendrocytes and astrocytes [107,108].”
From Ageing, Cellular Senescence and Neurodegenerative Disease (2018) · cites this paper as [108]
In the citing paper
“The predicted progenitors expressed proliferation (Mki67) and known markers (Pax6, Rspo2/3, Wnt5a/3a/1, Fabp7, clusters 7 and 8 in Figure 2A,B S2B; STAR Methods), previously reported for precursors of ependymal cells and cortical neurons (Kriegstein and Alvarez-Buylla, 2009), with Wnt1 having the most specific expression (Figure S2G).”
From A cellular and spatial map of the choroid plexus across brain ventricles and ages (2021) · cites this paper as Kriegstein and Alvarez-Buylla, 2009
In the citing paper
“In embryos, subsets of glial cells expressed markers of neural progenitor/stem-like cells (e.g. Pax6, Nes, Sox2, Rspo2/3) or of oligodendrocyte precursor cells (OPCs, e.g. Olig1, Olig2) (Kriegstein and Alvarez-Buylla, 2009) (Figure 2A, S2A,B).”
From A cellular and spatial map of the choroid plexus across brain ventricles and ages (2021) · cites this paper as Kriegstein and Alvarez-Buylla, 2009
In the citing paper
“Validation and use of this mouse line revealed to be very powerful in the identification of several new genes and biological processes regulating cortical development (31).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
In the citing paper
“our group previously concluded that a transient up-or down-regulation specifically in DP compared to both their PP progenitors and N progeny (on-and off-switch transcripts, respectively) represented a hallmark of functional commitment to the neurogenic lineage (31,36).”
From MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis (2020) · cites this paper as [31]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Neurogenesis in the adult human hippocampus
Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369
Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 4,786
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,586
Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127 · cited 1×
“Astrocytes may retain fundamental properties and positional information linked to the original array of RG in the developing brain (Rakic 1988).”
BackgroundMechanisms and Functional Implications of Adult Neurogenesis
Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007
Running enhances neurogenesis, learning, and long-term potentiation in mice
van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426
Research works printed but not linked: 7
- 10.1016/S0092-8674(00)80783-7 · DOI · Paper page
- Hajós F, 1981, Acta Morphol. Acad. Sci. Hung., 29, 361
- Magini J, 1888, Arch. Ital. Biol., 10, 384
- Miyata T, 2008, Dev. Growth Differ., 50, S105
- Retzius G, 1894, Biol. Unters., 6, 1
- Smart IH, 1973, J. Anat., 116, 67
- 10.1523/JNEUROSCI.18-20-08331.1998 · DOI
Cited by
Sorted by citations
Items 301–400 of 1,011
The role of Notch signaling in adult neurogenesis
Imayoshi, I., & Kageyama, R. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8186-0 · Cited by 102
Gebara, E., Sultan, S., Kocher-Braissant, J., & Toni, N. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00145 · Cited by 102
Purushothaman, A., Sugahara, K., & Faissner, A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.298430 · Cited by 104
An O2-Sensitive Glomus Cell-Stem Cell Synapse Induces Carotid Body Growth in Chronic Hypoxia
Platero-Luengo, A., González-Granero, S., Durán, R., Castro, B. D., Piruat, J. I., García‐Verdugo, J. M., Pardal, R., & López‐Barneo, J. (2014) · Cell · doi:10.1016/j.cell.2013.12.013 · Cited by 102
Synapse formation on adult‐born hippocampal neurons
Toni, N., & Sultan, S. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07604.x · Cited by 105
Vitucci, M., Hayes, D. N., & Miller, C. R. (2010) · British Journal of Cancer · doi:10.1038/sj.bjc.6606031 · Cited by 101
Perez, J. D., Rubinstein, N. D., & Dulac, C. G. (2016) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113708 · Cited by 106
Ventricular Zone Disruption in Human Neonates With Intraventricular Hemorrhage
McAllister, J. P., Guerra, M. M., Castañeyra-Ruiz, L., Jimenez, A. J., Domínguez-Pinos, D., Sival, D. A., den Dunnen, W. F. A., Morales, D. M., Schmidt, R. E., Rodríguez, E. M., et al. (2017) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlx017 · Cited by 101
Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes
Tiwari, N., Pataskar, A., Péron, S., Thakurela, S., Sahu, S. K., Figueres‐Oñate, M., Marichal, N., López‐Mascaraque, L., Tiwari, V. K., & Berninger, B. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.09.008 · Cited by 104
Sonic hedgehog signaling in the postnatal brain
Álvarez-Buylla, A., & Ihrie, R. A. (2014) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2014.05.008 · Cited by 100
Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury
Jinnou, H., Sawada, M., Kawase, K., Kaneko, N., Herranz‐Pérez, V., Miyamoto, T., Kawaue, T., Miyata, T., Tabata, Y., Akaike, T., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.11.005 · Cited by 100
TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway
Falace, A., Buhler, E., Fadda, M., Watrin, F., Lippiello, P., Pallesi‐Pocachard, E., Baldelli, P., Benfenati, F., Zara, F., Represa, A., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1316294111 · Cited by 104
Falk, S., & Götz, M. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.10.025 · Cited by 99
Centrosome anchoring regulates progenitor properties and cortical formation
Shao, W., Yang, J., He, M., Yu, X.-Y., Lee, C. H., Yang, Z., Joyner, A. L., Anderson, K. V., Zhang, J., Tsou, M.-F. B., et al. (2020) · Nature · doi:10.1038/s41586-020-2139-6 · Cited by 102
The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity
Heraud-Farlow, J. E., & Kiebler, M. A. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.05.009 · Cited by 99
Type-1 Cannabinoid Receptor Signaling in Neuronal Development
Gaffuri, A.-L., Ladarré, D., & Lenkei, Z. (2012) · Pharmacology · doi:10.1159/000339075 · Cited by 107
Binary recombinase systems for high-resolution conditional mutagenesis
Hermann, M., Stillhard, P., Wildner, H., Seruggia, D., Kapp, V., Sánchez-Iranzo, H., Mercader, N., Montoliu, L., Zeilhofer, H. U., & Pelczar, P. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1361 · Cited by 99
Adult neural stem cells: an endogenous tool to repair brain injury?
Bellenchi, G. C., Volpicelli, F., Piscopo, V. E. C., Perrone‐Capano, C., & di Porzio, U. (2012) · Journal of Neurochemistry · doi:10.1111/jnc.12084 · Cited by 101
Therapeutic Plasticity of Neural Stem Cells
Ottoboni, L., von Wunster, B., & Martino, G. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00148 · Cited by 105
4E-BP is a target of the GCN2–ATF4 pathway during Drosophila development and aging
Kang, M., Vasudevan, D., Kang, K., Kim, K., Park, J.-E., Zhang, N., Zeng, X., Neubert, T. A., Marr, M. T., & Ryoo, H. D. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201511073 · Cited by 102
Neurogenesis and vascularization of the damaged brain using a lactate-releasing biomimetic scaffold
Álvarez, Z., Castaño, Ó., Castells, A. A., Mateos‐Timoneda, M. A., Planell, J. A., Engel, E., & Alcántara, S. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.02.051 · Cited by 97
Shaping the brain: The emergence of cortical structure and folding
Akula, S. K., Exposito-Alonso, D., & Walsh, C. A. (2023) · Developmental Cell · doi:10.1016/j.devcel.2023.11.004 · Cited by 104
Baffet, A. D., Hu, D. J. K., & Vallee, R. B. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.04.022 · Cited by 97
Neural Stem Cell Niches in Health and Diseases
Decimo, I., Bifari, F., Krampera, M., & Fumagalli, G. F. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212799859611 · Cited by 102
Aromatase, estrogen receptors and brain development in fish and amphibians
Coumailleau, P., Pellegrini, E., Adrio, F., Diotel, N., Cano‐Nicolau, J., Nasri, A., Vaillant, C., & Kah, O. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.07.002 · Cited by 96
Blood‐brain barrier development: Systems modeling and predictive toxicology
Saili, K. S., Zurlinden, T. J., Schwab, A. J., Silvin, A., Baker, N., Hunter, E. S., Ginhoux, F., & Knudsen, T. B. (2017) · Birth Defects Research · doi:10.1002/bdr2.1180 · Cited by 101
The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Kumar, V., Umair, Z., Kumar, S., Goutam, R. S., Park, S., & Kim, J. (2021) · Fluids and Barriers of the CNS · doi:10.1186/s12987-021-00265-0 · Cited by 102
Transgenic fluorescent zebrafish lines that have revolutionized biomedical research
Choe, C. P., Choi, S., Kee, Y., Kim, J. M., Kim, S.-H., Lee, Y., Park, H., & Ro, H. (2021) · Laboratory Animal Research · doi:10.1186/s42826-021-00103-2 · Cited by 104
Mending the broken brain: neuroimmune interactions in neurogenesis
Molina‐Holgado, E., & Molina‐Holgado, F. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06849.x · Cited by 96
Coevolution of radial glial cells and the cerebral cortex
Romero, C. D. J., & Borrell, V. (2015) · Glia · doi:10.1002/glia.22827 · Cited by 102
Zhu, S., Barshow, S., Wildonger, J., Jan, L. Y., & Jan, Y. N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1118595109 · Cited by 96
RNA-Binding Protein FXR2 Regulates Adult Hippocampal Neurogenesis by Reducing Noggin Expression
Guo, W., Zhang, L., Christopher, D. M., Teng, Z., Fausett, S. R., Liu, C.-M., George, O. L., Klingensmith, J., Jin, P., & Zhao, X. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.027 · Cited by 96
Beattie, R., Postiglione, M. P., Burnett, L. E., Laukoter, S., Streicher, C., Pauler, F. M., Xiao, G., Klezovitch, O., Vasioukhin, V. I., Ghashghaei, T., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.012 · Cited by 100
Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, M., Knoblich, J. A., & van Lohuizen, M. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.93 · Cited by 98
Sandvig, I., Augestad, I. L., Håberg, A. K., & Sandvig, A. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.13959 · Cited by 94
Defining stem cell types: understanding the therapeutic potential of ESCs, ASCs, and iPS cells
Álvarez, C. V., García-Lavandeira, M., Garcia-Rendueles, M. E. R., Díaz‐Rodriguez, E., Garcia-Rendueles, Á. R., Pérez-Romero, S., Vila, T. V., Rodrigues, J. S., Lear, P., & Bravo, S. B. (2012) · Journal of Molecular Endocrinology · doi:10.1530/jme-12-0072 · Cited by 97
Bowman, A. N., van Amerongen, R., Palmer, T. D., & Nusse, R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305411110 · Cited by 94
Gli3 Is Required for Maintenance and Fate Specification of Cortical Progenitors
Wang, H., Ge, G., Uchida, Y., Luu, B., & Ahn, S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4892-10.2011 · Cited by 93
Wullimann, M. F. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00027 · Cited by 93
Daynac, M., Morizur, L., Chicheportiche, A., Mouthon, M., & Boussin, F. D. (2016) · Scientific Reports · doi:10.1038/srep21505 · Cited by 93
Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB
Rolando, C., Erni, A., Grison, A., Beattie, R., Engler, A., Gokhale, P. J., Milo, M., Wegleiter, T., Jessberger, S., & Taylor, V. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.07.003 · Cited by 93
Saino, O., Taguchi, A., Nakagomi, T., Nakano‐Doi, A., Kashiwamura, S., Doe, N., Nakagomi, N., Soma, T., Yoshikawa, H., Stern, D. M., et al. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22410 · Cited by 95
Mechanisms of astrocytogenesis in the mammalian brain
Namihira, M., & Nakashima, K. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.06.002 · Cited by 93
Najas, S., Arranz, J., Lochhead, P. A., Ashford, A. L., Oxley, D., Delabar, J. M., Cook, S. J., Barallobre, M. J., & Arbonés, M. L. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.01.010 · Cited by 92
Classic and novel stem cell niches in brain homeostasis and repair
Lin, R., & Iacovitti, L. (2015) · Brain Research · doi:10.1016/j.brainres.2015.04.029 · Cited by 96
Johnson, K. A., Barragan, J., Bashiruddin, S., Smith, C. J., Tyrrell, C., Parsons, M. J., Doris, R., Kucenas, S., Downes, G. B., Velez, C. M., et al. (2016) · Glia · doi:10.1002/glia.22990 · Cited by 92
A fluorescent toolkit for spatiotemporal tracking of apoptotic cells in living Drosophila tissues
Schott, S., Ambrosini, A., Barbaste, A., Benassayag, C., Gracia, M., Proag, A., Rayer, M., Monier, B., & Suzanne, M. (2017) · Development · doi:10.1242/dev.149807 · Cited by 92
AGING OF THE SUBVENTRICULAR ZONE NEURAL STEM CELL NICHE.
Conover, J. C., & Shook, B. A. (2011) · Europe PMC (PubMed Central) · Cited by 92
Candelario, K. M., Shuttleworth, C. W., & Cunningham, L. A. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12204 · Cited by 92
Enteric nervous system development: Recent progress and future challenges
Laranjeira, C., & Pachnis, V. (2009) · Autonomic Neuroscience · doi:10.1016/j.autneu.2009.09.001 · Cited by 92
The involvement of astrocytes in early‐life adversity induced programming of the brain
Abbink, M. R., van Deijk, A. F., Heine, V. M., Verheijen, M. H. G., & Kőrösi, A. (2019) · Glia · doi:10.1002/glia.23625 · Cited by 95
Unlocking epigenetic codes in neurogenesisPreprint
Yao, B., & Jin, P. (2014) · Genes & Development · doi:10.1101/gad.241547.114 · Cited by 97
Neural Stem Cell of the Hippocampus
Rolando, C., & Taylor, V. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416022-4.00007-x · Cited by 99
Henderson, K. W., Gupta, J., Tagliatela, S., Litvina, E. Y., Zheng, X., Zandt, M. A. V., Woods, N. I., Grund, E. M., Lin, D., Royston, S. E., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0005-14.2014 · Cited by 91
Ohata, S., Aoki, R., Kinoshita, S., Yamaguchi, M., Tsuruoka-Kinoshita, S., Tanaka, H., Wada, H., Watabe, S., Tsuboi, T., Masai, I., et al. (2011) · Neuron · doi:10.1016/j.neuron.2010.12.026 · Cited by 95
Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?
Moulson, A. J., Squair, J. W., Franklin, R. J. M., Tetzlaff, W., & Assinck, P. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.703810 · Cited by 97
Gómez, O., Arévalo‐Martín, Á., García‐Ovejero, D., Ortega‐Gutiérrez, S., Cisneros, J. A., Almazán, G., Sanchez-Rodriguez, M. A., Molina‐Holgado, F., & Molina‐Holgado, E. (2010) · Glia · doi:10.1002/glia.21061 · Cited by 90
Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia
Colognato, H., & Tzvetanova, I. D. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20966 · Cited by 92
Radial glia regulate vascular patterning around the developing spinal cord
Matsuoka, R. L., Marass, M., Avdesh, A., Helker, C. S., Maischein, H.-M., Grosse, A. S., Kaur, H., Lawson, N. D., Herzog, W., & Stainier, D. Y. (2016) · eLife · doi:10.7554/elife.20253 · Cited by 84
Folding of the Cerebral Cortex Requires Cdk5 in Upper-Layer Neurons in Gyrencephalic Mammals
Shinmyo, Y., Terashita, Y., Duong, T. A. D., Hamabe‐Horiike, T., Kawasumi, M., Hosomichi, K., Tajima, A., & Kawasaki, H. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.08.024 · Cited by 89
Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX
Niu, W., Zou, Y., Shen, C., & Zhang, C. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1038-11.2011 · Cited by 90
Fate Restriction and Multipotency in Retinal Stem Cells
Centanin, L., Höckendorf, B., & Wittbrodt, J. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.11.004 · Cited by 96
Radial glial cells in the adult dentate gyrus: what are they and where do they come from?
Berg, D. A., Bond, A. M., Ming, G.-L., & Song, H. (2018) · F1000Research · doi:10.12688/f1000research.12684.1 · Cited by 89
Harris, L., Genovesi, L. A., Gronostajski, R. M., Wainwright, B. J., & Piper, M. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24182 · Cited by 92
Nuclear Factor Kappa B Signaling Initiates Early Differentiation of Neural Stem Cells
Zhang, Y., Liu, J., Yao, S., Li, F., Xin, L., Lai, M., Bracchi-Ricard, V. C., Xu, H., Yen, W., Meng, W., et al. (2011) · Stem Cells · doi:10.1002/stem.1006 · Cited by 91
Brault, J., Khou, C., Basset, J., Coquand, L., Fraisier, V., Frenkiel, M., Goud, B., Manuguerra, J., Pardigon, N., & Baffet, A. D. (2016) · EBioMedicine · doi:10.1016/j.ebiom.2016.07.018 · Cited by 88
Regulation of active and quiescent somatic stem cells by Notch signaling
Sueda, R., & Kageyama, R. (2019) · Development Growth & Differentiation · doi:10.1111/dgd.12626 · Cited by 88
Purinergic receptors in embryonic and adult neurogenesis
Oliveira‐Giacomelli, Á., Illés, P., & Ulrich, H. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.10.008 · Cited by 88
Bonfanti, L., & Nácher, J. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.05.002 · Cited by 89
Radner, S., Banos, C. C., Bachay, G., Li, Y. N., Hunter, D. D., Brunken, W. J., & Yee, K. T. (2012) · Developmental Neurobiology · doi:10.1002/dneu.22057 · Cited by 89
Radial glia – from boring cables to stem cell stars
Malatesta, P., & Götz, M. (2013) · Development · doi:10.1242/dev.085852 · Cited by 87
The functional significance of newly born neurons integrated into olfactory bulb circuits
Sakamoto, M., Kageyama, R., & Imayoshi, I. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00121 · Cited by 96
Evidence for neural stem cells in the medaka optic tectum proliferation zones
Alunni, A., Hermel, J., Heuzé, A., Bourrat, F., Jamen, F., & Joly, J. (2010) · Developmental Neurobiology · doi:10.1002/dneu.20799 · Cited by 86
Astrocitos en las enfermedades neurodegenerativas (I): función y caracterización molecular
Guillamón-Vivancos, T., Gómez‐Pinedo, U., & Matías‐Guiu, J. (2013) · Neurología · doi:10.1016/j.nrl.2012.12.007 · Cited by 98
Current Challenges for the Advancement of Neural Stem Cell Biology and Transplantation Research
Reekmans, K., Praet, J., Daans, J., Reumers, V., Pauwels, P., der Linden, A. V., Berneman, Z. N., & Ponsaerts, P. (2011) · Stem Cell Reviews and Reports · doi:10.1007/s12015-011-9266-2 · Cited by 87
Independent Anchoring and Assembly Mechanisms of INAD Signaling Complexes inDrosophilaPhotoreceptors
Tsunoda, S., Sun, Y., Suzuki, E., & Zuker, C. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-01-00150.2001 · Cited by 86
Kawai, H., Kawaguchi, D., Kuebrich, B. D., Kitamoto, T., Yamaguchi, M., Gotoh, Y., & Furutachi, S. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.0001-17.2017 · Cited by 85
Gálvez‐Contreras, A. Y., Quiñones‐Hinojosa, A., & González-Pérez, Ó. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00258 · Cited by 89
The extracellular matrix niche microenvironment of neural and cancer stem cells in the brain
Reinhard, J., Brösicke, N., Theocharidis, U., & Faissner, A. (2016) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2016.05.002 · Cited by 87
Tenascin-C in the matrisome of neural stem and progenitor cells
Faissner, A., Roll, L., & Theocharidis, U. (2016) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2016.11.003 · Cited by 87
Immunological regulation of neurogenic niches in the adult brain
González-Pérez, Ó., Gutierrez-Fernandez, F., Lopez-Virgen, V., Collas-Aguilar, J., Quinones-Hinojosa, A., & García‐Verdugo, J. M. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.08.053 · Cited by 90
Zhang, Y., Liu, G., Guo, T., Liang, X. G., Du, H., Yang, L., Bhaduri, A., Li, X., Xu, Z., Zhang, Z., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.027 · Cited by 89
Self-citationFerreting out stem cells from their niches
Fuchs, E. V., & Horsley, V. (2011) · Nature Cell Biology · doi:10.1038/ncb0511-513 · Cited by 87
Regeneration of Zebrafish CNS: Adult Neurogenesis
Ghosh, S., & Hui, S. P. (2016) · Neural Plasticity · doi:10.1155/2016/5815439 · Cited by 90
Neurogenesis and Gliogenesis in Nervous System Plasticity and Repair
Frisén, J. (2016) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-111315-124953 · Cited by 83
Wnt Signaling Regulates Multipolar-to-Bipolar Transition of Migrating Neurons in the Cerebral Cortex
Boitard, M., Bocchi, R., Egervari, K., Petrenko, V., Viale, B., Gremaud, S., Zgraggen, E., Salmon, P., & Kiss, J. Z. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.01.061 · Cited by 83
Vascular Influence on Ventral Telencephalic Progenitors and Neocortical Interneuron Production
Tan, X., Liu, W. A., Zhang, X., Shi, W., Ren, S., Li, Z., Brown, K. N., & Shi, S. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.02.023 · Cited by 88
Aging, Cellular Senescence, and Progressive Multiple Sclerosis
Papadopoulos, D., Magliozzi, R., Mitsikostas, D. D., Gorgoulis, V. G., & Nicholas, R. S. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00178 · Cited by 80
Adult Neural Stem Cells: Response to Stroke Injury and Potential for Therapeutic Applications
Barkho, B. Z., & Zhao, X. (2011) · Current Stem Cell Research & Therapy · doi:10.2174/157488811797904362 · Cited by 86
Pituitary stem cells: Where do we stand?
Vankelecom, H. E. J., & Chen, J. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.08.018 · Cited by 85
Brumby, A. M., Goulding, K. R., Schlosser, T., Loi, S., Galea, R. C., Khoo, P., Bolden, J. E., Aigaki, T., Humbert, P. O., & Richardson, H. E. (2011) · Genetics · doi:10.1534/genetics.111.127910 · Cited by 84
Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2
Andreu-Agulló, C., Maurin, T., Thompson, C. B., & Lai, E. C. (2011) · Nature · doi:10.1038/nature10712 · Cited by 82
The aged brain: genesis and fate of residual progenitor cells in the subventricular zone
Capilla‐González, V., Herranz‐Pérez, V., & García‐Verdugo, J. M. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00365 · Cited by 82
Seong, K.-J., Lee, H.-G., Kook, M. S., Ko, H.-M., Jung, J., & Kim, W.-J. (2016) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2016.20.1.41 · Cited by 82
Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations
Hao, Z.-Z., Wei, J.-R., Xiao, D., Liu, R., Xu, N., Tang, L., Huang, M., Shen, Y., Xing, C., Huang, W., et al. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01073-x · Cited by 87
MicroRNA-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin
Stary, C. M., Xu, L., Sun, X., Ouyang, Y., White, R., Leong, J., Li, J., Xiong, X., & Giffard, R. G. (2015) · Stroke · doi:10.1161/strokeaha.114.007041 · Cited by 83
Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain
Gadadhar, A., Marr, R. A., & Lazarov, O. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4767-10.2011 · Cited by 81
Neuronal and astrocytic primary cilia in the mature brain
Sterpka, A., & Chen, X. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.10.002 · Cited by 80
Yu, T., Washington, P. M., & Kernie, S. G. (2014) · The Neuroscientist · doi:10.1177/1073858414563616 · Cited by 80
Lattke, M., Magnutzki, A., Walther, P., Wirth, T., & Baumann, B. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0182-12.2012 · Cited by 80
Metadata
- Authors
- Kriegstein, A., & Alvarez-Buylla, A.
- Affiliations
- University of California, San Francisco (US)
- The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Departments of Neurology, Neurological Surgery, and School of Medicine, University of California, San Francisco, California 94143-0525;,
- ORCID
- Kriegstein, Arnold
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2009-06-01
- Volume
- 32
- Issue
- 1
- Pages
- 149-184
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- PMC
- PMC3086722
- OpenAlex
- W2172266256
- Cited by
- 2,475
- References
- 263
- Citations by year
- 2026: 87 · 2025: 141 · 2024: 138 · 2023: 131 · 2022: 133 · 2021: 168 · 2020: 162 · 2019: 147 · 2018: 166 · 2017: 155 · 2016: 162 · 2015: 129 · 2014: 167 · 2013: 172 · 2012: 155
- FWCI
- 12.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (R01NS035710, R01NS028478, R01NS021223)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- neural stem cells, radial glia, astrocytes, intermediate progenitor cells, transit amplifying cells, neuronal lineage, neuroepithelium, adult neurogenesis, brain development, lineage tracing, brain repair
- MeSH terms
- Animals, Cell Differentiation, Central Nervous System, Humans, Neuroglia, Neurons, Stem Cells, Gene Expression Regulation, Developmental, Cell Lineage, Adult Stem Cells, Neurogenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
