Cited by 3,033Cellular transport and secretionAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Functions of Lysosomes

de Duve, Christian, Wattiaux, Robert·1966·Annual Review of Physiology

DOI 10.1146/annurev.ph.28.030166.002251

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Locke, M., & Collins, J. V. (1967) · Science · doi:10.1126/science.155.3761.467 · Cited by 102
Proteolysis and myelin breakdown: a review of recent histochemical and biochemical studies
Hallpike, J. F., & Adams, C. W. M. (1969) · The Histochemical Journal · doi:10.1007/bf01012862 · Cited by 102
Bovine splenic nerve: characterization of noradrenaline‐containing vesicles and other cell organelles by density gradient centrifugation
Hörtnagl, H., Hörtnagl, H., & Winkler, H. J. S. (1969) · The Journal of Physiology · doi:10.1113/jphysiol.1969.sp008954 · Cited by 102
Compartmentalization of the Edinburgh Human Metabolic Network
Hao, T., Ma, H., Zhao, X., & Goryanin, I. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-393 · Cited by 100
“The lysosome membrane enables an acidic internal environment (pH less than 5 rather than around 7 in the cytosol) to maximize the enzyme activities [1].”
Background

Authors: de Duve, C., & Wattiaux, R.
Venue: Annual Review of Physiology
Publisher: Annual Reviews
Published: 1966-03
Volume: 28
Issue: 1
Pages: 435-492
ISSN: 0066-4278 (ISSN-L)
1545-1585
DOI: 10.1146/annurev.ph.28.030166.002251
OpenAlex: W2138948114
Cited by: 3,033
References: 0
Citations by year: 2026: 25 · 2025: 56 · 2024: 58 · 2023: 50 · 2022: 47 · 2021: 75 · 2020: 68 · 2019: 54 · 2018: 79 · 2017: 65 · 2016: 70 · 2015: 63 · 2014: 64 · 2013: 64 · 2012: 51
FWCI: 111.33
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Calcium signaling and nucleotide metabolism
Keywords: lysosomes, lysosomal function, intracellular digestion, acid hydrolases, membrane trafficking, endocytosis, autophagy
MeSH terms: Animals, Lysosomes, In Vitro Techniques

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