Cited by 3,033Cellular transport and secretionAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Functions of Lysosomes

de Duve, Christian, Wattiaux, Robert·1966·Annual Review of Physiology

DOI 10.1146/annurev.ph.28.030166.002251

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“[2] De Duve C, Wattiaux R.”
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Chevronnay, H. P. G., Janssens, V., Smissen, P. V. D., et al. (2014) · Journal of the American Society of Nephrology · doi:10.1681/asn.2013060598 · Cited by 85
“* P , 0.05 for comparison with content by apical membrane fusion ( i.e. , lysosomal defecation 39 ) (ref.”
Influential
MiR-155-5p inhibits PDK1 and promotes autophagy via the mTOR pathway in cervical cancer
Wang, F., Shan, S., Huo, Y., Xie, Z., Fang, Y., Qi, Z., Chen, F., Li, Y., & Sun, B. (2018) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2018.04.005 · Cited by 85
Intracellular Events and Cell Fate in Filovirus Infection
Olejnik, J., Ryabchikova, E. I., Corley, R. B., & Mühlberger, E. (2011) · Viruses · doi:10.3390/v3081501 · Cited by 89
“Autophagic cells feature vacuolization and formation of double membraned vesicles, the autophagosomes, for degradation of cellular content [131,132].”
Background
The Gliointerstitial System of Molluscs
Nicaise, G. (1973) · International review of cytology · doi:10.1016/s0074-7696(08)61938-5 · Cited by 85
Cytochemical evidence for the leakage of acid phosphatase through ultrastructurally intact lysosomal membranes
Brunk, U. T., & Dricsson, J. L. E. (1972) · The Histochemical Journal · doi:10.1007/bf01011128 · Cited by 85
Intracellular localization of 125I-labeled insulin in hepatocytes from intact rat liver.
Carpentier, J. L., Görden, P., Barazzone, P., et al. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.6.2803 · Cited by 85
Vital marking of single cells in developing tissues: India ink injection to trace tissue movements in hydra
Campbell, R. D. (1973) · Journal of Cell Science · doi:10.1242/jcs.13.3.651 · Cited by 85

Authors: de Duve, C., & Wattiaux, R.
Venue: Annual Review of Physiology
Publisher: Annual Reviews
Published: 1966-03
Volume: 28
Issue: 1
Pages: 435-492
ISSN: 0066-4278 (ISSN-L)
1545-1585
DOI: 10.1146/annurev.ph.28.030166.002251
OpenAlex: W2138948114
Cited by: 3,033
References: 0
Citations by year: 2026: 25 · 2025: 56 · 2024: 58 · 2023: 50 · 2022: 47 · 2021: 75 · 2020: 68 · 2019: 54 · 2018: 79 · 2017: 65 · 2016: 70 · 2015: 63 · 2014: 64 · 2013: 64 · 2012: 51
FWCI: 111.33
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Calcium signaling and nucleotide metabolism
Keywords: lysosomes, lysosomal function, intracellular digestion, acid hydrolases, membrane trafficking, endocytosis, autophagy
MeSH terms: Animals, Lysosomes, In Vitro Techniques

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