Cited by 55Exercise and Physiological ResponsesMuscle metabolism and nutritionCardiovascular and exercise physiology

Can elite athletes benefit from dietary nitrate supplementation?

Jonvik, Kristin L., Nyakayiru, Jean, van Loon, Luc J. C., Verdijk, Lex B.·2015·Journal of Applied Physiology

Abstract

n/a due to viewpoint guidelines.

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Crossref · 10.1152/japplphysiol.00232.2015

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  • Inorganic NO3- supplementation, particularly when administered chronically, can improve performance in moderately trained endurance athletes (VO2peak < 60 mL/kg/min), but the impact on highly trained or elite endurance athletes (VO2peak ≥ 60 mL/kg/min) is not promising.

    “Although there is evidence that inorganic NO 3 -supplementation, particularly when administered chronically, can improve performance in moderately trained endurance athletes ( V O 2 peak < 60 mL/kg/min), the impact of NO 3 -on highly trained or elite endurance athletes ( V O 2 peak ≥ 60 mL/kg/min) is not promising and has been the topic of much debate (e.g., 66) (Figure 2).”

    From Dietary Nitrate and Physical Performance (2018) · cites this paper as [66]

  • There is good evidence that nitrate/BJ supplementation can enhance sports performance in moderate caliber athletes and individuals among elite athlete populations, with emphasis on adequate protocols and sports/scenarios relying on less-oxidative type II muscle fibres and conditions of hypoxia or acidosis.

    “Nevertheless, there seems good evidence that nitrate/BJ supplementation can enhance sports performance in moderate caliber athletes and individuals among elite athlete populations [130], with emphasis on adequate supplementation protocols and sports or scenarios which rely on the recruitment of the lessoxidative type II muscle fibres, and local or environmental conditions of hypoxia or acidosis (e”
  • The situations in which nitrate supplementation results in benefits to sports performance are presently unclear, particularly in elite athletes who seem less responsive to nitrate supplementation protocols.

    “However, the situations in which this results in benefits to sports performance are presently unclear, particularly in the case of elite athletes who seem to be less responsive to nitrate supplementation protocols [131,132].”
  • The apparent lack of effect of nitrate supplementation in elite endurance athletes may be a function of their athletic status (e.g., superior background NO production or reduced number of Type II muscle fibres) as well as an interaction with the conditions of use.

    “The apparent lack of effect in elite endurance athletes may be a function of their athletic status (e.g., due to a superior background NO production or reduced number of Type II muscle fibres in which nitrate supplementation might be most suited to targeting conditions of hypoxia or acidosis [19,56,61,62]) as well as an interaction with the conditions of use.”

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Authors
Jonvik, K. L., Nyakayiru, J., van Loon, L. J. C., & Verdijk, L. B.
Affiliations
  • HAN University of Applied Sciences (NL)
  • Maastricht University (NL)
  • NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, Maastricht, The Netherlands; and
Corresponding author
Verdijk, Lex B.
Venue
Journal of Applied Physiology
Published
2015-09-15
Volume
119
Issue
6
Pages
759-761
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
OpenAlex
W2288088734
Cited by
55
References
30
Citations by year
2026: 2 · 2025: 3 · 2024: 1 · 2023: 6 · 2022: 4 · 2021: 8 · 2020: 4 · 2019: 5 · 2018: 11 · 2017: 5 · 2016: 4 · 2015: 2
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
  • Research Publications (Maastricht University) (publishedVersion)
  • Research Bank (Australian Catholic University) (submittedVersion)
  • Research Publications (Maastricht University) (submittedVersion)
Funders
Netherlands Organisation for Scientific Research | Technologiestichting STW (Technology Foundation STW) (12877)
Topics
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
dietary nitrate, nitrate supplementation, elite athletes, exercise performance, blood flow, oxygen delivery
MeSH terms
Carbonated Beverages, Humans, Nitrates, Nitrogen Oxides, Exercise, Dietary Supplements, Athletes

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