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Cited by 26Cardiovascular and exercise physiologyMuscle metabolism and nutritionExercise and Physiological Responses

Effects of Dietary Nitrates on Time Trial Performance in Athletes with Different Training Status: Systematic Review

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Hlinský, Tomáš, Kumstát, Michal, Vajda, Petr·2020·Nutrients
DOI 10.3390/nu12092734PMC PMC7551808
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Abstract

Much research has been done in sports nutrition in recent years as the demand for performance-enhancing substances increases. Higher intake of nitrates from the diet can increase the bioavailability of nitric oxide (NO) via the nitrate–nitrite–NO pathway. Nevertheless, the increased availability of NO does not always lead to improved performance in some individuals. This review aims to evaluate the relationship between the athlete’s training status and the change in time trial performance after increased dietary nitrate intake. Articles indexed by Scopus and PubMed published from 2015 to 2019 were reviewed. Thirteen articles met the eligibility criteria: clinical trial studies on healthy participants with different training status (according to VO2max), conducting time trial tests after dietary nitrate supplementation. The PRISMA guidelines were followed to process the review. We found a statistically significant relationship between VO2max and ergogenicity in time trial performance using one-way ANOVA (p = 0.001) in less-trained athletes (VO2 < 55 mL/kg/min). A strong positive correlation was observed in experimental situations using a chronic supplementation protocol but not in acute protocol situations. In the context of our results and recent histological observations of muscle fibres, there might be a fibre-type specific role in nitric oxide production and, therefore, supplement of ergogenicity.

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Authors
Hlinský, T., Kumstát, M., & Vajda, P.
Affiliations
Masaryk University (CZ)
Corresponding author
Hlinský, Tomáš
ORCID
Venue
Nutrients
Publisher
MDPI AG
Published
2020-09-08
Volume
12
Issue
9
Pages
2734
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu12092734
PMC
PMC7551808
OpenAlex
W3084042367
Cited by
26
References
36
Citations by year
2026: 4 · 2025: 1 · 2024: 1 · 2023: 7 · 2022: 10 · 2021: 3
FWCI
1.03
Type
journal article
Language
en
Open access
Licence
Locations
  • Nutrients (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Veřejné služby Informačního systému (Masarykiana Brunensis Universitas) (submittedVersion, other-oa)
Funders
Masarykova Univerzita (MUNI/A/1201/2018)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
dietary nitrate, nitrate supplementation, time trial performance, training status, VO2max, nitric oxide bioavailability, nitrate-nitrite-nitric oxide pathway, ergogenic aids, trained vs untrained athletes, muscle fiber type
MeSH terms
Humans, Nitrates, Nitric Oxide, Oxygen Consumption, Physical Endurance, Time Factors, Databases, Factual, Muscle Fibers, Skeletal, Dietary Supplements, Athletic Performance, Athletes, Performance-Enhancing Substances

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