Extracellular Calcium Fluctuations and Intracellular Potentials in the Cortex During the Slow Sleep Oscillation
Abstract
During slow wave sleep the main activity of cortical neurons consists of synchronous and rhythmic alternations of the membrane potential between depolarized and hyperpolarized values. The latter are long-lasting (200–600 ms) periods of silence. The mechanisms responsible for this periodical interruption of cortical network activity are unknown. Here we report a decrease of ∼20% in the extracellular calcium concentration ([Ca]out) progressively taking place in the cortex between the onset and the offset of the depolarizing phase of the slow sleep oscillation. Since [Ca]out exerts a high gain modulation of synaptic transmission, we estimated the associated transmitter release probability and found a corresponding 50% drop. Thus the periods of silence occurring in the cortical network during slow wave sleep are promoted by recurrent [Ca]out depletions.
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Extracellular Ca2+ concentrations are increased during the downstate, which enhances synaptic efficacy, such that a single spike generated in this condition may effectively excite the whole network.
“Moreover, extracellular Ca 2ϩ concentrations are increased during the downstate, which enhances synaptic efficacy, such that a single spike generated in this condition may effectively excite the whole network (238, 790), in particular when such spikes originate from neurons in deep cortical layers with larger numbers of synaptic contacts to other neurons (188).”
From About Sleep's Role in Memory (2013) · cites this paper as [790]
Cites
Steriade, M., Nunez, A., & Amzica, F. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03252.1993 · Cited by 1,903 · see citing works
Self-citationCellular and network mechanisms of rhythmic recurrent activity in neocortex
Sanchez-Vives, M. V., & McCormick, D. A. (2000) · Nature Neuroscience · doi:10.1038/79848 · Cited by 1,539 · see citing works
Co‐operative action of calcium ions in transmitter release at the neuromuscular junction
Dodge, F. A., & Rahamimoff, R. (1967) · The Journal of Physiology · doi:10.1113/jphysiol.1967.sp008367 · Cited by 1,315 · see citing works
Steriade, M., Nunez, A., & Amzica, F. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03266.1993 · Cited by 894 · see citing works
Self-citationPasti, L., Volterra, A., Pozzan, T., & Carmignoto, G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-20-07817.1997 · Cited by 794 · see citing works
Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships
Contreras, D., & Steriade, M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00604.1995 · Cited by 700 · see citing works
Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation
Steriade, M., Amzica, F., & Contreras, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-01-00392.1996 · Cited by 646 · see citing works
Self-citationLow-frequency (<1Hz) oscillations in the human sleep electroencephalogram
Achermann, P., & Borbély, A. A. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00186-3 · Cited by 577 · see citing works
Calcium control of transmitter release at a cerebellar synapse.
Mintz, I., Sabatini, B., & Regehr, W. (1995) · Neuron · doi:10.1016/0896-6273(95)90155-8 · Cited by 551 · see citing works
Further study of the role of calcium in synaptic transmission
Katz, B., & Miledi, R. (1970) · The Journal of Physiology · doi:10.1113/jphysiol.1970.sp009095 · Cited by 462 · see citing works
The elemental principles of calcium signaling
Bootman, M. D., & Berridge, M. J. (1995) · Cell · doi:10.1016/0092-8674(95)90179-5 · Cited by 454 · see citing works
Stafstrom, C. E., Schwindt, P. C., Chubb, M. C., & Crill, W. E. (1985) · Journal of Neurophysiology · doi:10.1152/jn.1985.53.1.153 · Cited by 414 · see citing works
Contreras, D., Timofeev, I., & Steriade, M. (1996) · The Journal of Physiology · doi:10.1113/jphysiol.1996.sp021488 · Cited by 374 · see citing works
The K-complex: Its slow (<1-Hz) rhythmicity and relation to delta waves
Amzica, F., & Steriade, M. (1997) · Neurology · doi:10.1212/wnl.49.4.952 · Cited by 329 · see citing works
Self-citationSchwindt, P. C., Spain, W. J., Foehring, R. C., Chubb, M. C., & Crill, W. E. (1988) · Journal of Neurophysiology · doi:10.1152/jn.1988.59.2.450 · Cited by 310 · see citing works
Steriade, M., Amzica, F., & Nunez, A. (1993) · Journal of Neurophysiology · doi:10.1152/jn.1993.70.4.1385 · Cited by 302 · see citing works
Self-citationSynchronized sleep oscillations and their paroxysmal developments
Steriade, M., Contreras, D., & Amzica, F. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90105-8 · Cited by 301 · see citing works
Self-citationNicholson, C., ten Bruggencate, G., Steinberg, R., & Stöckle, H. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.3.1287 · Cited by 267 · see citing works
Calcium and potassium changes in extracellular microenvironment of cat cerebellar cortex
Nicholson, C., ten Bruggencate, G., Stöckle, H., & Steinberg, R. (1978) · Journal of Neurophysiology · doi:10.1152/jn.1978.41.4.1026 · Cited by 267 · see citing works
Short- and long-range neuronal synchronization of the slow (< 1 Hz) cortical oscillation
Amzica, F., & Steriade, M. (1995) · Journal of Neurophysiology · doi:10.1152/jn.1995.73.1.20 · Cited by 230 · see citing works
Self-citationQian, J., Colmers, W. F., & Saggau, P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08169.1997 · Cited by 210 · see citing works
The Calcium Pump and Sodium-Calcium Exchange in Squid Axons
DiPolo, R., & Beaugé, L. (1983) · Annual Review of Physiology · doi:10.1146/annurev.ph.45.030183.001525 · Cited by 162 · see citing works
Dynamic coupling among neocortical neurons during evoked and spontaneous spike-wave seizure activity
Steriade, M., & Amzica, F. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.72.5.2051 · Cited by 145 · see citing works
Self-citationIntrinsic programmes of growth and survival in developing vertebrate neurons
Davies, A. M. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90104-x · Cited by 142 · see citing works
Fast Extracellular Calcium Transients: Involvement in Epileptic Processes
Pumain, R., Kurcewicz, I., & Louvel, J. (1983) · Science · doi:10.1126/science.6623068 · Cited by 137 · see citing works
Depletion of calcium in the synaptic cleft of a calyx‐type synapse in the rat brainstem
Borst, J. G. G., & Sakmann, B. J. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.00123.x · Cited by 132 · see citing works
Hippocampal synapses: do they talk to their neighbours?
Rusakov, D. A., Kullmann, D. M., & Stewart, M. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01425-3 · Cited by 117 · see citing works
Modulation of extracellular calcium and its functional implications.
Nicholson, C. (1980) · PubMed · Cited by 78 · see citing works
Somjen, G. G. (1980) · Journal of Neurophysiology · doi:10.1152/jn.1980.44.4.617 · Cited by 76 · see citing works
Simon, N. R., Manshanden, I., & da Silva, F. H. L. (2000) · Brain Research · doi:10.1016/s0006-8993(00)01974-0 · Cited by 73 · see citing works
Heinemann, U., & Pumain, R. (1981) · Neuroscience Letters · doi:10.1016/0304-3940(81)90063-x · Cited by 54 · see citing works
Bollmann, J. H., Helmchen, F., Borst, J. G. G., & Sakmann, B. J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-24-10409.1998 · Cited by 52 · see citing works
Computational Properties of Peri-Dendritic Calcium Fluctuations
Egelman, D. M., & Montague, P. R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-21-08580.1998 · Cited by 38 · see citing works
Igelmund, P., Zhao, Y. Q., & Heinemann, U. (1996) · Experimental Brain Research · doi:10.1007/bf00228623 · Cited by 37 · see citing works
Calcium electrogenesis in neocortical pyramidal neurons in vivo
Paré, D., & Lang, E. J. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00323.x · Cited by 29 · see citing works
Dendritic Spikes and Their Influence on Extracellular Calcium Signaling
Wiest, M., Eagleman, D. M., King, R., & Montague, P. R. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.3.1329 · Cited by 28 · see citing works
Alici, K., & Heinemann, U. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(94)11211-z · Cited by 13 · see citing works
Do extracellular Ca 2+ signals carry information through neural tissue?
King, R., Wiest, M., Montague, P. R., & Eagleman, D. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01516-7 · Cited by 10 · see citing works
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Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · see citing works
“Moreover, extracellular Ca(2) concentrations are increased during the downstate, which enhances synaptic efficacy, such that a single spike generated in this condition may effectively excite the whole network (238, 790), in particular when such spikes originate from neurons in deep cortical layers with larger numbers…”
BackgroundBoosting slow oscillations during sleep potentiates memory
Marshall, L., Helgadóttir, H., Mölle, M., & Born, J. (2006) · Nature · doi:10.1038/nature05278 · Cited by 1,792 · see citing works
Reconstruction and Simulation of Neocortical Microcircuitry
Markram, H., Muller, E., Ramaswamy, S., Reimann, M. W., Abdellah, M., Sanchez, C. A., Ailamaki, A., Alonso-Nanclares, L., Antille, N., Arsever, S., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.029 · Cited by 1,705 · see citing works
Grouping of brain rhythms in corticothalamic systems
Steriade, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.10.029 · Cited by 1,296 · see citing works
Neuronal Plasticity in Thalamocortical Networks during Sleep and Waking Oscillations
Steriade, M., & Timofeev, I. (2003) · Neuron · doi:10.1016/s0896-6273(03)00065-5 · Cited by 638 · see citing works
Transcranial direct current stimulation during sleep improves declarative memory
Marshall, L., Mölle, M., Hallschmid, M., & Born, J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2725-04.2004 · Cited by 548 · see citing works
Compte, A., Sanchez-Vives, M. V., McCormick, D. A., & Wang, X. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00845.2002 · Cited by 536 · see citing works
Impact of Network Activities on Neuronal Properties in Corticothalamic Systems
Steriade, M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.1 · Cited by 530 · see citing works
Declarative memory consolidation: mechanisms acting during human sleep
Gais, S., & Born, J. (2004) · Learning & Memory · doi:10.1101/lm.80504 · Cited by 536 · see citing works
The corticothalamic system in sleep
Steriade, M. (2003) · Frontiers in bioscience · doi:10.2741/1043 · Cited by 504 · see citing works
Nowak, L. G., Azouz, R., Sanchez-Vives, M. V., Gray, C. M., & McCormick, D. A. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00580.2002 · Cited by 443 · see citing works
Neocortical seizures: initiation, development and cessation
Timofeev, I., & Steriade, M. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.08.051 · Cited by 370 · see citing works
Interaction between neocortical and hippocampal networks via slow oscillations
Sirota, A., & Buzsáki, G. (2005) · Thalamus and Related Systems · doi:10.1017/s1472928807000258 · Cited by 270 · see citing works
Volgushev, M., Chauvette, S., Mukovski, M., & Timofeev, I. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0279-06.2006 · Cited by 289 · see citing works
Origin of Active States in Local Neocortical Networks during Slow Sleep Oscillation
Chauvette, S., Volgushev, M., & Timofeev, I. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq009 · Cited by 266 · see citing works
Acetylcholine systems and rhythmic activities during the waking—sleep cycle
Steriade, M. (2004) · Progress in brain research · doi:10.1016/s0079-6123(03)45013-9 · Cited by 227 · see citing works
CAP, epilepsy and motor events during sleep: The unifying role of arousal
Parrino, L., Halasz, P., Tassinari, C. A., & Terzano, M. G. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.12.004 · Cited by 219 · see citing works
Hypersensitivity of the Anesthesia-Induced Comatose Brain
Kroeger, D., & Amzica, F. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3440-07.2007 · Cited by 215 · see citing works
Self-citationAmzica, F., Massimini, M., & Manfridi, A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-03-01042.2002 · Cited by 198 · see citing works
Self-citationSchabus, M., Dang‐Vu, T. T., Heib, D. P. J., Boly, M., Desseilles, M., Vandewalle, G., Schmidt, C., Albouy, G., Darsaud, A., Gais, S., et al. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00040 · Cited by 191 · see citing works
Neuronal metabolism governs cortical network response state.
Cunningham, M., Pervouchine, D., Racca, C., Kopell, N., Davies, C., Jones, R. S. G., Traub, R., & Whittington, M. (2006) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0600604103 · Cited by 174 · see citing works
An astrocyte-dependent mechanism for neuronal rhythmogenesis
Morquette, P., Verdier, D., Kadala, A., Féthière, J., Philippe, A. G., Robitaille, R., & Kolta, A. (2015) · Nature Neuroscience · doi:10.1038/nn.4013 · Cited by 168 · see citing works
The functional significance of K-complexes
Amzica, F., & Steriade, M. (2002) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0181 · Cited by 161 · see citing works
Self-citationReverberation, storage, and postsynaptic propagation of memories during sleepPreprint
Ribeiro, S. T. G., & Nicolelis, M. A. L. (2004) · Learning & Memory · doi:10.1101/lm.75604 · Cited by 149 · see citing works
tDCS possibly stimulates glial cells
Ruohonen, J., & Karhu, J. (2012) · Clinical Neurophysiology · doi:10.1016/j.clinph.2012.02.082 · Cited by 145 · see citing works
Cortical Inhibition during Burst Suppression Induced with Isoflurane Anesthesia
Ferron, J.-F., Kroeger, D., Chever, O., & Amzica, F. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5176-08.2009 · Cited by 140 · see citing works
Self-citationVyazovskiy, V. V., Faraguna, U., Cirelli, C., & Tononi, G. (2009) · Journal of Neurophysiology · doi:10.1152/jn.91157.2008 · Cited by 134 · see citing works
Brain Electrical Activity and Sensory Processing during Waking and Sleep States
Steriade, M. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50016-1 · Cited by 134 · see citing works
Polack, P., Mahon, S., Chávez, M., & Charpier, S. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn237 · Cited by 133 · see citing works
Higgs, M. H., Slee, S. J., & Spain, W. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1792-06.2006 · Cited by 124 · see citing works
Sleep-related epileptic behaviors and non-REM-related parasomnias: Insights from stereo-EEG
Gibbs, S. A., Proserpio, P., Terzaghi, M., Pigorini, A., Sarasso, S., Russo, G. L., Tassi, L., & Nobili, L. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.05.002 · Cited by 123 · see citing works
Interstitial ions: A key regulator of state-dependent neural activity?
Rasmussen, R. N., O’Donnell, J., Ding, F., & Nedergaard, M. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101802 · Cited by 113 · see citing works
Sleep slow oscillation and plasticity
Timofeev, I., & Chauvette, S. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.03.019 · Cited by 118 · see citing works
Neuronal Substrates of Sleep and Epilepsy
Steriade, M. (2001) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541711 · Cited by 116 · see citing works
Massimini, M., Rosanova, M., & Mariotti, M. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00373.2002 · Cited by 124 · see citing works
Self-citationModulation of synaptic transmission in neocortex by network activities
Crochet, S., Chauvette, S., Boucetta, S., & Timofeev, I. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03932.x · Cited by 106 · see citing works
Glial and Neuronal Interactions during Slow Wave and Paroxysmal Activities in the Neocortex
Amzica, F. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.10.1101 · Cited by 103 · see citing works
Self-citationModulation of intercellular calcium signaling in astrocytes by extracellular calcium and magnesium
Stout, C. E., & Charles, A. C. (2003) · Glia · doi:10.1002/glia.10257 · Cited by 97 · see citing works
Synaptic Strength Modulation after Cortical Trauma: A Role in Epileptogenesis
Avramescu, S., & Timofeev, I. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0643-08.2008 · Cited by 91 · see citing works
Bock, M. D., Decrock, E., Wang, N., Bol, M., Vinken, M., Bultynck, G., & Leybaert, L. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.04.016 · Cited by 86 · see citing works
Connexons and pannexons: newcomers in neurophysiology
Cheung, G. T. Y., Chever, O., & Rouach, N. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00348 · Cited by 80 · see citing works
Hairston, I. S., Peyron, C., Denning, D. P., Ruby, N. F., Flores, J., Sapolsky, R. M., Heller, H. C., & O’Hara, B. F. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00894.2003 · Cited by 79 · see citing works
Poornima, V., Madhupriya, M., Kootar, S., Sujatha, G., Kumar, A., & Bera, A. K. (2011) · Journal of Molecular Neuroscience · doi:10.1007/s12031-011-9646-8 · Cited by 75 · see citing works
Blume, C., del Giudice, R., Wisłowska, M., Heib, D. P. J., & Schabus, M. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.05.056 · Cited by 73 · see citing works
Outcome prediction in acute monohemispheric stroke via magnetoencephalography
Tecchio, F., Pasqualetti, P., Zappasodi, F., Tombini, M., Lupoi, D., Vernieri, F., & Rossini, P. M. (2007) · Journal of Neurology · doi:10.1007/s00415-006-0355-0 · Cited by 70 · see citing works
Mishra, A., Fousková, P., Angelovski, G., Balogh, E., Mishra, A. K., Logothetis, N. K., & Tóth, É. (2008) · Inorganic Chemistry · doi:10.1021/ic7017456 · Cited by 70 · see citing works
Synaptic Transmission and Plasticity in an Active Cortical Network
Reig, R., & Sanchez-Vives, M. V. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000670 · Cited by 62 · see citing works
Intracellular, In Vivo , Dynamics of Thalamocortical Synapses in Visual Cortex
Sedigh-Sarvestani, M., Vigeland, L. E., Fernández‐Lamo, I., Taylor, M. M., Palmer, L. A., & Contreras, D. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3370-16.2017 · Cited by 60 · see citing works
In vitro seizure like events and changes in ionic concentration
Antônio, L. L., Anderson, M., Angamo, E. A., Gabriel, S., Klaft, Z., Liotta, A., Salar, S., Sandow, N., & Heinemann, U. (2015) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2015.08.014 · Cited by 60 · see citing works
Lemieux, M., Chauvette, S., & Timofeev, I. (2014) · Journal of Neurophysiology · doi:10.1152/jn.00858.2013 · Cited by 54 · see citing works
Steyn‐Ross, M. L., Steyn‐Ross, D. A., & Sleigh, J. W. (2013) · Physical Review X · doi:10.1103/physrevx.3.021005 · Cited by 55 · see citing works
Thalamic Drive of Cortical Parvalbumin-Positive Interneurons during Down States in Anesthetized Mice
Zucca, S., Pasquale, V., Roig, P. L. D. L., Panzeri, S., & Fellin, T. (2019) · Current Biology · doi:10.1016/j.cub.2019.04.007 · Cited by 48 · see citing works
Synaptic Interactions Between Thalamic and Cortical Inputs Onto Cortical Neurons In Vivo
Fuentealba, P., Crochet, S., Timofeev, I., & Steriade, M. (2004) · Journal of Neurophysiology · doi:10.1152/jn.01105.2003 · Cited by 54 · see citing works
Selective Amplification of Neocortical Neuronal Output by Fast Prepotentials InVivo
Crochet, S. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh071 · Cited by 54 · see citing works
Bock, M. D., Culot, M., Wang, N., Costa, A. D., Decrock, E., Bol, M., Bultynck, G., Cecchelli, R., & Leybaert, L. (2012) · Brain Research · doi:10.1016/j.brainres.2012.06.046 · Cited by 53 · see citing works
Neuronal Synchronization and Thalamocortical Rhythms during Sleep, Wake, and Epilepsy
Timofeev, I., Bazhenov, M., Seigneur, J., & B, T. J. S. A. (2012) · Oxford University Press eBooks · doi:10.1093/med/9780199746545.003.0013 · Cited by 53 · see citing works
Basic Mechanisms of Sleep and Epilepsy
Sinha, S. R. (2011) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0b013e3182120d41 · Cited by 52 · see citing works
Neuronal Synchronization and Thalamocortical Rhythms in Sleep, Wake and Epilepsy
Timofeev, I., Bazhenov, M., Seigneur, J., & B, T. J. S. A. (2012) · Europe PMC (PubMed Central) · Cited by 50 · see citing works
A Subtype of Inhibitory Interneuron with Intrinsic Persistent Activity in Human and Monkey Neocortex
Wang, B., Yin, L., Zou, X., Ye, M., Liu, Y., He, T., Deng, S., Jiang, Y., Zheng, R., Wang, Y., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.02.018 · Cited by 40 · see citing works
A thalamo-cortical neural mass model for the simulation of brain rhythms during sleep
Cona, F., Lacanna, M., & Ursino, M. (2014) · Journal of Computational Neuroscience · doi:10.1007/s10827-013-0493-1 · Cited by 49 · see citing works
Aivar, P., Valero, M., Bellistri, E., & de la Prida, L. M. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2826-13.2014 · Cited by 49 · see citing works
Crochet, S., Fuentealba, P., Cissé, Y., Timofeev, I., & Steriade, M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj008 · Cited by 48 · see citing works
Amzica, F. (2002) · Journal of Physiology-Paris · doi:10.1016/s0928-4257(02)00008-6 · Cited by 47 · see citing works
Self-citationNeuronal plasticity and thalamocortical sleep and waking oscillations
Timofeev, I. (2011) · Progress in brain research · doi:10.1016/b978-0-444-53839-0.00009-0 · Cited by 44 · see citing works
Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent
MacRenaris, K. W., Ma, Z., Krueger, R. L., Carney, C. E., & Meade, T. J. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00561 · Cited by 44 · see citing works
Pedrosa, R., Nazari, M., Mohajerani, M. H., Knöpfel, T., Stella, F., & Battaglia, F. P. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2204959119 · Cited by 42 · see citing works
Preparations and applications of synthetic linked azamacrocycle ligands and complexes
Timmons, J. C., & Hubin, T. J. (2009) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2009.09.018 · Cited by 43 · see citing works
Tartaglia, E. M., & Brunel, N. (2017) · Scientific Reports · doi:10.1038/s41598-017-12033-y · Cited by 42 · see citing works
EEG slow-wave coherence changes in propofol-induced general anesthesia: experiment and theory
Wang, K., Steyn‐Ross, M. L., Steyn‐Ross, D. A., Wilson, M. T., & SLEIGH, J. W. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00215 · Cited by 37 · see citing works
Guidetti, M., Arlotti, M., Bocci, T., Bianchi, A. M., Parazzini, M., Ferrucci, R., & Priori, A. (2022) · Biomedicines · doi:10.3390/biomedicines10102333 · Cited by 41 · see citing works
Marshall, L., Mölle, M., & Jan Born, A. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00458-5 · Cited by 37 · see citing works
From Maxwell's equations to the theory of current‐source density analysis
Gratiy, S. L., Halnes, G., Denman, D. J., Hawrylycz, M., Koch, C., Einevoll, G. T., & Anastassiou, C. A. (2017) · European Journal of Neuroscience · doi:10.1111/ejn.13534 · Cited by 36 · see citing works
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Chauvette, S., Soltani, S., Seigneur, J., & Timofeev, I. (2015) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2015.08.030 · Cited by 33 · see citing works
Molaee-Ardekani, B., Senhadji, L., Shamsollahi, M. B., Vahdat, B. V., & Wodey, É. (2007) · Physical Review E · doi:10.1103/physreve.76.041911 · Cited by 33 · see citing works
Hardingham, N. R., Bannister, N. J., Read, J. C. A., Fox, K. D., Hardingham, G. E., & Jack, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5128-05.2006 · Cited by 32 · see citing works
Physiology of Sleep and Wakefulness as it Relates to the Physiology of Epilepsy
Amzica, F. (2002) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-200212000-00002 · Cited by 32 · see citing works
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Bruni, O., Ferri, R., Novelli, L., Finotti, E., Terribili, M., Troianiello, M., Valente, D., Sabatello, U., & Curatolo, P. (2009) · Developmental Neuropsychology · doi:10.1080/87565640903133418 · Cited by 31 · see citing works
Liao, F., Taishi, P., Churchill, L., Urza, M. J., & Krueger, J. M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6047-09.2010 · Cited by 31 · see citing works
Peyrache, A. (2010) · Frontiers in Systems Neuroscience · doi:10.3389/neuro.06.018.2009 · Cited by 28 · see citing works
Lower Serum Calcium Levels Associated with Disrupted Sleep and Rest–Activity Rhythm in Shift Workers
Jeon, Y.-S., Yu, S., Kim, C., Lee, H. J., Yoon, I., & Kim, T. (2022) · Nutrients · doi:10.3390/nu14153021 · Cited by 26 · see citing works
Network-timing-dependent plasticity
Delattre, V., Keller, D. X., Perich, M. G., Markram, H., & Muller, E. B. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00220 · Cited by 24 · see citing works
Delta dipole density and strength in acute monohemispheric stroke
Zappasodi, F., Tombini, M., Milazzo, D., Rossini, P. M., & Tecchio, F. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.02.017 · Cited by 24 · see citing works
Barros-Barbosa, A. R., Lobo, M. G., Ferreirinha, F., Correia-de-Sá, P., & Cordeiro, J. M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.08.026 · Cited by 23 · see citing works
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Karameh, F. N., Dahleh, M. A., Brown, E. N., & Massaquoi, S. G. (2006) · Biological Cybernetics · doi:10.1007/s00422-006-0090-8 · Cited by 22 · see citing works
Isbister, J. B., Ecker, A., Pokorny, C., Bolaños‐Puchet, S., Santander, D. E., Arnaudon, A., Awile, O., Barros-Zulaica, N., Alonso, J. B., Boci, E., et al. (2026) · eLife · doi:10.1101/2023.05.17.541168 · Cited by 21 · see citing works
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Durkin, J., & Aton, S. J. (2019) · Annual Review of Vision Science · doi:10.1146/annurev-vision-091718-014715 · Cited by 20 · see citing works
Glial Cells in the Genesis and Regulation of Circadian Rhythms
Chi-Castañeda, D., & Ortega, A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00088 · Cited by 20 · see citing works
Rózsa, M., Tóth, M., Oláh, G., Baka, J., Lákovics, R., Barzó, P., & Tamás, G. (2023) · Science Advances · doi:10.1126/sciadv.ade4511 · Cited by 19 · see citing works
Stereotypical spatiotemporal activity patterns during slow-wave activity in the neocortex
Fucke, T., Suchanek, D., Nawrot, M. P., Seamari, Y., Heck, D. H., Aertsen, A., & Boucsein, C. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00811.2010 · Cited by 19 · see citing works
Newkirk, G. S., Guan, D., Dembrow, N. C., Armstrong, W. E., Foehring, R. C., & Spain, W. J. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab266 · Cited by 19 · see citing works
Detecting cell assemblies by NMF-based clustering from calcium imaging data
Nagayama, M., Aritake, T., Hino, H., Kanda, T., Miyazaki, T., Yanagisawa, M., Akaho, S., & Murata, N. (2022) · Neural Networks · doi:10.1016/j.neunet.2022.01.023 · Cited by 17 · see citing works
Small Lesion Size Is Associated with Sleep-Related Epilepsy in Focal Cortical Dysplasia Type II
Jin, B., Hu, W., Ye, L., Krishnan, B., Aung, T., Jones, S. E., Najm, I., Alexopoulos, A. V., Zhang, K., Zhu, J., et al. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00106 · Cited by 17 · see citing works
Qi, G., Yang, D., Ding, C., & Feldmeyer, D. (2020) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2020.00005 · Cited by 17 · see citing works
Kroeger, D., Tamburri, A., Amzica, F., & Attila Gabor, S. I. K. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00497.2009 · Cited by 17 · see citing works
Self-citationNita, D. A., Steriade, M., & Amzica, F. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.050310 · Cited by 17 · see citing works
Self-citationRecent Evidence of Memory Processing in Sleep
Pavlides, C., & Ribeiro, S. T. G. (2003) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198574002.003.0017 · Cited by 16 · see citing works
Boucetta, S., Crochet, S., Chauvette, S., Seigneur, J., & Timofeev, I. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.12.001 · Cited by 15 · see citing works
The role of calcium and CaMKII in sleep
Wang, Y., Minami, Y., Ode, K. L., & Ueda, H. R. (2022) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2022.1059421 · Cited by 14 · see citing works
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Adams, C. J., Krueger, R. L., & Meade, T. J. (2020) · ACS Chemical Biology · doi:10.1021/acschembio.9b00638 · Cited by 14 · see citing works
Brain Stimulation During Sleep
Marshall, L., & Jan Born, A. (2011) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2010.12.003 · Cited by 11 · see citing works
- Authors
- Massimini, M., & Amzica, F.
- Affiliations
- Université Laval (CA)
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 2001-03-01
- Volume
- 85
- Issue
- 3
- Pages
- 1346-1350
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- OpenAlex
- W2208002446
- Cited by
- 160
- References
- 38
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 4 · 2023: 1 · 2022: 6 · 2021: 2 · 2020: 5 · 2019: 7 · 2018: 3 · 2017: 6 · 2016: 1 · 2015: 10 · 2014: 9 · 2013: 5 · 2012: 9
- FWCI
- 6.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neurophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- slow-wave sleep, extracellular calcium, hyperpolarization, synaptic transmission, calcium depletion, cortical network activity, sleep spindles
- MeSH terms
- Animals, Biological Clocks, Calcium, Cats, Cerebral Cortex, Electric Stimulation, Electrodes, Implanted, Electroencephalography, Extracellular Space, Membrane Potentials, Microelectrodes, Nerve Net, Neurons, Pons, Sleep, Tegmentum Mesencephali
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