Physical activity, aging, and physiological function

Harridge, Stephen D. R.; Lazarus, Norman R.

doi:10.1152/physiol.00029.2016

Cited by 214Physical Activity and HealthCardiovascular and exercise physiologyExercise and Physiological Responses

Physical activity, aging, and physiological function

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Harridge, Stephen D. R., Lazarus, Norman R.·2017·Physiology

DOI 10.1152/physiol.00029.2016

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Abstract

Human evolution suggests that the default position for health is to be physically active. Inactivity, by contrast, has serious negative effects on health across the lifespan. Therefore, only in physically active people can the inherent aging process proceed unaffected by disuse complications. In such individuals, although the relationship between age and physiological function remains complex, function is generally superior with health, well being, and the aging process optimized.

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Inactivity has a serious negative effect on the health of the individual.
“Inactivity, in fact, has a serious negative effect on the health of the individual [104].”
From Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption (2020) · cites this paper as [104]

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Authors: Harridge, S. D. R., & Lazarus, N. R.
Affiliations: King's College London (GB)
Corresponding author: Harridge, Stephen D. R.
ORCID: Harridge, Stephen D. R.
Lazarus, Norman R.
Venue: Physiology
Publisher: American Physiological Society
Published: 2017-03
Volume: 32
Issue: 2
Pages: 152-161
ISSN: 0886-1714 (ISSN-L)
1548-9213
1548-9221
DOI: 10.1152/physiol.00029.2016
OpenAlex: W2591216245
Cited by: 214
References: 94
Citations by year: 2026: 14 · 2025: 21 · 2024: 26 · 2023: 33 · 2022: 25 · 2021: 39 · 2020: 25 · 2019: 14 · 2018: 14 · 2017: 3
FWCI: 1.88
Type: journal article
Language: en
Open access: green
kclpure.kcl.ac.uk
Licence: other-oa
Locations: Physiology (publishedVersion)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion, other-oa)
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords: physical activity, aging, physiological function, physical inactivity, disuse, human evolution, well-being
MeSH terms: Cardiorespiratory Fitness, Aging, Animals, Cardiovascular System, Humans, Life Style, Physical Conditioning, Animal, Exercise, Muscle, Skeletal

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