The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function

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The chemokine system in diverse forms of macrophage activation and polarization

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Toll-Like Receptors

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

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Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

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A dual-component particulate dressing for simultaneous microenvironment modulation and tissue regeneration in infected diabetic wounds

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A Biomimetic Janus Fibrous Membrane for Scarless Achilles Tendon Regeneration via Synergistic Modulation of an Oxidative-Inflammatory Cascade

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Mitochondria-targeted strategies in tumor immunity

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Mechanisms of MOF‐Based Biomaterials in Skin Wound Healing: Antibacterial, Immunomodulatory, Angiogenic, and Neurogenic Effects

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Redox interactions of immune cells and muscle in the regulation of exercise-induced pain and analgesia: implications on the modulation of muscle nociceptor sensory neurons

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Redox state associated with antitumor and immunomodulatory peptides in cancer

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Inhibition of melanoma using a nanoceria-based prolonged oxygen-generating phototherapy hydrogel

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An in vivo study to investigate an original intramedullary bone graft harvesting technology

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Poly- d -lysine coated nanoparticles to identify pro-inflammatory macrophages

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Oral administration of berberine represses macrophage activation-associated benign prostatic hyperplasia: a pivotal involvement of the NF-κB

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Laser-mediated osteoblast ablation triggers a pro-osteogenic inflammatory response regulated by reactive oxygen species and glucocorticoid signaling in zebrafish

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M13 phage coated surface elicits an anti-inflammatory response in BALB/c and C57BL/6 peritoneal macrophages

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Azithromycin reduces hemoglobin-induced innate neuroimmune activation

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Human tissue-resident peritoneal macrophages reveal resistance towards oxidative cell stress induced by non-invasive physical plasma

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Mitigated toxicity of polystyrene nanoplastics in combination exposure with copper ions by transformation into copper (I) oxide: Inhibits the oxidative potential of nanoplastics

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Acoustically Driven Hybrid Nanocrystals for In Vivo Pancreatic Cancer Treatment

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Mechanisms of anastomotic leakage in colorectal cancer surgery: unraveling the roles of inflammation, immunity, and microbiota – a narrative review

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Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress

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Macrophage metabolism in inflammatory heart disease: new insights and therapeutic implications

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Promastigotes of Leishmania donovani exhibited sensitivity towards the high altitudinal plant Cicer microphyllum

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Effect of Wear-Corrosion of Reduced Graphene Oxide Functionalized with Hyaluronic Acid on Inflammatory and Proteomic Response of J774A.1 Macrophages

Sánchez-López, L., Ropero, N., Chico, B., Fagali, N., Rı́os, V. D. L., Escudero, M. L., García-Alonso, M. C., & Lozano, R. M. (2023) · Metals · doi:10.3390/met13030598 · Cited by 8

Synergistic effects of cerium-containing bioactive glasses and apoptotic extracellular vesicles alleviate bisphosphonate-related osteonecrosis of jaw

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Anti-inflammatory effects of ginsenoside compound K in ethanol-stimulated macrophages by modulating sirtuin 1

Gwon, Y., Moon, C. Y., Lee, E., Im, S., & Kang, H. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106218 · Cited by 8

Induced Autophagy of Macrophages and the Regulation of Inflammatory Effects by Perovskite Nanomaterial LaNiO3

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Crocus sativus Extract as a Biological Agent for Disease-Modifying Therapy of Collagenase-Induced Mouse Model of Osteoarthritis

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Lead Induces Different Responses of Two Subpopulations of Phagocytes in the Holothurian Eupentacta fraudatrix

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Nur77 influences immunometabolism to regulate the release of proinflammatory cytokines and the formation of lipid bodies during Mycobacterium tuberculosis infection of macrophages

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Implantable conductive polymer bioelectrode with enzymatic antioxidant activity for enhanced tissue responses and in vivo performance

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Onion Peel Extract Prevents Intestinal Inflammation via AMK-Activated Protein Kinase Activation in Caco-2/HT-29 Cells

Balogun, O. T., Brownmiller, C., Lee, S., & Kang, H. W. (2024) · Nutrients · doi:10.3390/nu16213609 · Cited by 7

Deodeokaloid, a New Indole Alkaloid N-Glycoside and Bioactive Phenolic Compounds from the Roots of Codonopsis lanceolata

Cho, Y. R., Hong, J.-H., Kang, D., Ko, Y., Ahn, M., & Kim, K. H. (2024) · Plants · doi:10.3390/plants13223243 · Cited by 7

Topology-dependent T 2 relaxivity in Fe 3 O cluster-based MOFs for enhanced tumor monitoring via MRI

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SHP-1 negatively regulates LPS-induced M1 polarization, phagocytic activity, inflammation and oxidative stress in primary macrophages of Chinese tongue sole (Cynoglossus semilaevis)

Wang, N., Tan, S., Liu, H., Nie, Y., Wang, M., Liu, H., Han, S., Wu, Z., Ma, J., & Sha, Z. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110375 · Cited by 7

Nutritional strategies targeting age-related skeletal muscle fibrosis: underlying mechanisms

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Glycolytic reprogramming in macrophage polarization: New horizons in the treatment of tumor diseases

Wang, D., & Guan, H. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111940 · Cited by 8

Role of necroptosis in pulpitis: integration of bacterial infection, immune imbalance, and oxidative stress

Wang, X., Wang, Y., Pang, Z., Gong, P., Ma, X., Qiu, Y., Li, J., Peng, L., & Liu, Z. (2025) · PeerJ · doi:10.7717/peerj.20209 · Cited by 7

Crosstalk between synovial macrophages and fibroblasts in rheumatoid arthritis.

Saeki, N., & Imai, Y. (2023) · PubMed · doi:10.14670/hh-18-628 · Cited by 8

Amplified P2X3 pathway activity in muscle afferent dorsal root ganglion neurons and exercise pressor reflex regulation in hindlimb ischaemia–reperfusion

Qin, L., Li, Q., & Li, J. (2024) · Experimental Physiology · doi:10.1113/ep091616 · Cited by 7

HSPA9 reduction exacerbates symptoms and cell death in DSS-Induced inflammatory colitis

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The abortive SARS‐CoV‐2 infection of osteoclast precursors promotes their differentiation into osteoclasts

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A promising strategy for combating bacterial infections through the use of light-triggered ROS in Ce6-immobilized hydrogels

Hong, S. H., Lee, M. H., Go, E. J., & Park, J. (2024) · Regenerative Biomaterials · doi:10.1093/rb/rbae101 · Cited by 7

Berberine-Loaded Nanoparticles Combat Oxidative and Nitrosative Stress to Reprogram Macrophages in Rheumatoid Arthritis

Shukla, V., Umesh, & Purohit, A. (2024) · BioNanoScience · doi:10.1007/s12668-024-01637-0 · Cited by 7

Cellular Contributors to Bone Homeostasis

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The Opposing Role of Propionate in Modulating Listeria monocytogenes Intracellular Infections

Hobbs, L., Allen, L., Bias, M., Johnson, S. M., DeRespiris, H., Diallo, C. K., Bui, L., & Sun, Y. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.721801 · Cited by 7

Metabolic Response of RAW 264.7 Macrophages to Exposure to Crude Particulate Matter and a Reduced Content of Organic Matter

Jankowska-Kieltyka, M., Roman, A., Mikrut, M., Kowalska, M., van Eldik, R., & Nalepa, I. (2021) · Toxics · doi:10.3390/toxics9090205 · Cited by 7

Effects of Volatile Anaesthetics and Iron Dextran on Chronic Inflammation and Antioxidant Defense System in Rats

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Redox aspects of cytotoxicity and anti-neuroinflammatory profile of chloroquine and hydroxychloroquine in serum-starved BV-2 microglia

Račková, L., & Csekes, E. (2022) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2022.116084 · Cited by 7

Redox‐Triggered Nanomedicine via Lymphatic Delivery: Inhibition of Melanoma Growth by Ferroptosis Enhancement and a Pt(IV)‐Prodrug Chemoimmunotherapy Approach

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PE_PGRS45 (Rv2615c) protein of Mycobacterium tuberculosis perturbs mitochondria of macrophages

Medha, M., Priyanka, P., Sharma, S., & Sharma, M. (2023) · Immunology and Cell Biology · doi:10.1111/imcb.12677 · Cited by 7

Altered expression of CXCR1 (IL-8R) in macrophages utilizing cell surface TNFR1 and IL-1 receptor during Staphylococcus aureus infection

Bishayi, B., Adhikary, R., Sultana, S., Dey, R., & Nandi, A. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2017.11.028 · Cited by 7

Dimethyl Fumarate Prevents HIV-Induced Lysosomal Dysfunction and Cathepsin B Release from Macrophages

Rosario-Rodríguez, L. J., Colón, K., Borges-Vélez, G., Negrón, K., & Meléndez, L. M. (2018) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-018-9794-5 · Cited by 7

Differences in macrophage pyroptosis and polarization induced by nano-/micro-calcium oxalate crystals

Tong, X., Nong, W.-J., Tan, R.-M., & Ouyang, J. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03549-x · Cited by 6

3D-Bioprinting of ROS-Responsive Curcumin-Loaded Hydrogel Scaffolds via Low-Temperature Extrusion for Enhancing Diabetic Wound Healing

Ma, C., Qiu, H., Chen, Y., Mueed, A., & You, L. (2026) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c02248 · Cited by 6

Extracellular Redox Balance as a Determinant of Immune Regulation and Tissue Inflammation

Seitz, R., Müller, M. A., & Gülow, K. (2026) · Antioxidants · doi:10.3390/antiox15030280 · Cited by 8

A chitosan-tea polyphenol composite hydrogel with integrated antibacterial, antioxidant and immunomodulatory functions for the tissue regeneration of MRSA-infected wounds

Zeng, Z., Kang, L., He, Y., Guan, Y., Cao, Y., Zhang, X., & Yuan, W.-E. (2026) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2026.109722 · Cited by 6

The role of reactive oxygen species in macrophage-mediated immune response against Mycobacterium tuberculosis

Ye, Z., Yang, Z., Zhang, J., Wang, Y., Yang, X., & Pang, Y. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.03.027 · Cited by 6

Reactive Oxygen and Nitrogen Species on Monocyte and Macrophage Biology

Jimenez‐Trinidad, F. R., Morini, S., Buffon, A., Prisco, A. D., Galati, G., Ciutiis, A. D., d’Aiello, A., Jiménez‐Altayó, F., Dantas, A. P., Liuzzo, G., et al. (2026) · Antioxidants · doi:10.3390/antiox15030389 · Cited by 7

Protective effect of 6′-Sialyllactose on LPS-induced macrophage inflammation via regulating Nrf2-mediated oxidative stress and inflammatory signaling pathways

Yu, H., Jin, Y., Jeon, H., Kim, L., & Heo, K. (2024) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2024.28.6.503 · Cited by 6

Anti-inflammatory cellular targets on neutrophils elucidated using a novel cell migration model and confocal microscopy: a clinical supplementation study

Smith, T., Engelbrecht, L., & Smith, C. (2018) · Journal of Inflammation · doi:10.1186/s12950-017-0177-0 · Cited by 6

Yersinia pseudotuberculosis Thermostable Toxin Dysregulates the Functional Activity of Two Types of Phagocytes in the Holothurian Eupentacta fraudatrix

Dolmatova, L. S., Анатольевна, У. О., & Тимченко, Н. Ф. (2019) · Biology Bulletin · doi:10.1134/s1062359019020043 · Cited by 6

Zinc ferrate nanoparticles for applications in medicine: synthesis, physicochemical properties, regulation of macrophage functions, and in vivo safety evaluation

Wang, Y., Liu, Y., Li, J., Xu, X., & Li, X. (2020) · Nanotoxicology · doi:10.1080/17435390.2020.1831094 · Cited by 6

The Antioxidative Effects of Picein and Its Neuroprotective Potential: A Review of the Literature

Elyasi, L., Rosenholm, J. M., Jesmi, F., & Jahanshahi, M. (2022) · Molecules · doi:10.3390/molecules27196189 · Cited by 6

Differential Effects of Dexmedetomidine on Gram-Positive and Gram-Negative Bacterial Killing and Phagocytosis

Maisat, W., Han, X., Koutsogiannaki, S., Soriano, S. G., & Yuki, K. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110327 · Cited by 6

New mesenchymal stem/stromal cell-based strategies for osteoarthritis treatment: targeting macrophage-mediated inflammation to restore joint homeostasis

Sapag, M. A., Lara-Barba, E., García-Guerrero, C., Herrera-Luna, Y., Flores-Elías, Y., Bustamante-Barrientos, F. A., Albornoz, G. G., Contreras-Fuentes, C., Yantén-Fuentes, L., Luque‐Campos, N., et al. (2025) · Journal of Molecular Medicine · doi:10.1007/s00109-025-02547-8 · Cited by 5

The unexplored relationship between spontaneous osteoclastogenesis and platelets in osteoporosis

Salamanna, F., Martino, A. C. D., Contartese, D., Faldini, C., Giavaresi, G., & Fini, M. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1584022 · Cited by 5

miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages

Neculachi, C. A., Nastase-Rusu, E.-G., Cherry, L., Marinescu-Colan, C. I., Tastsoglou, S., Cosman, B., Popa, A. M., Panciuc, C., Zaccagnini, G., Catrina, S., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1633163 · Cited by 5

ANXA6 Overexpression Causes Abnormal Decidual Macrophage-Trophoblast Crosstalk in Recurrent Spontaneous Abortion

Chen, X., Li, X., Ma, X. Q., Zhang, Y., Song, Q., & Yang, J. (2025) · International Journal of Biological Sciences · doi:10.7150/ijbs.111791 · Cited by 5

The influence of hypoxia‐mediated CEACAM6 upregulation on epithelial cell and macrophage response in the context of gastric cancer

Poirah, I., Chakraborty, D., Dixit, P., Samal, S., Banerjee, S., Mukherjee, T., Chattopadhyay, S., Nath, G., & Bhattacharyya, A. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14352 · Cited by 5

Zhike Pingchuan Granule suppresses interleukin (IL)-6 or the medium of M2 macrophages induced apoptosis in human bronchial epithelial cells

Ren, Y., Yan, Y., Zhen, L., Cao, C., Wang, Q., Zhang, Y., & Zhu, S. L. (2021) · Bioengineered · doi:10.1080/21655979.2021.1982309 · Cited by 5

Xanthone from Swertia chirata Exerts Chemotherapeutic Potential Against Colon Carcinoma

Barua, A., Choudhury, P., Nag, N. K., Nath, A., Kundagrami, S., Pal, A., Panda, C. K., & Saha, P. (2022) · Current Science · doi:10.18520/cs/v122/i1/47-55 · Cited by 5

Detection and characterization of free oxygen radicals induced protein adduct formation in differentiating macrophages

Manoharan, R. R., Sedlářová, M., Pospı́šil, P., & Prasad, A. (2023) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2023.130324 · Cited by 5

Global scientific trends update on macrophage polarization in rheumatoid arthritis: A bibliometric and visualized analysis from 2000 to 2022

Yuan, J., Feng, T., Guo, Y.-D., Luo, K., Wu, Q., Yu, S., & Zhou, H. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e19761 · Cited by 5

PDT-Induced Activation Enhanced by Hormone Response to Treatment

Domka, W., Bartusik‐Aebisher, D., Przygoda, M., Dynarowicz, K., Tomik, J., & Aebisher, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813917 · Cited by 5

Lithospermic acid targeting heat shock protein 90 attenuates LPS-induced inflammatory response via NF-кB signalling pathway in BV2 microglial cells

Guo, J., Li, C., Mai, F., Liang, J., Chen, Z.-H., Luo, J., Zhou, M., Wang, Y., & Yang, W.-T. (2025) · Immunologic Research · doi:10.1007/s12026-025-09600-1 · Cited by 5

Distinct Modulatory Effects of Fever-Range Hyperthermia on the Response of Breast Cancer Cells and Macrophages to Mistletoe (Viscum album L.) Extract

Kozłowski, H. M., Pawlikowska, M., Sobocińska, J., Jędrzejewski, T., Dzialuk, A., & Wrotek, S. (2021) · Pharmaceuticals · doi:10.3390/ph14060551 · Cited by 5

The Emerging Role of Anti-Hyperglycemic Agents for the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease

Pieralice, S., Amendolara, R., Berna, V., Manganaro, G., Zurru, A., D’Onofrio, L., Risi, R., Alfonsi, M., Maddaloni, E., & Buzzetti, R. (2025) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s528569 · Cited by 7

Advanced nanoplatforms for precise intervention of synovial inflammation in rheumatoid arthritis

Luo, W., Han, M., Cai, Q., Tan, Y., Gao, Y., Zhou, H., Yang, Z., Rodriguez, R. D. D., Tang, Y., & Ma, L. (2026) · Journal of Materials Chemistry B · doi:10.1039/d6tb00088f · Cited by 4

Modulation of Innate Immune Memory Dynamics by Subcellular Reactive Oxygen Species

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