The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function

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The chemokine system in diverse forms of macrophage activation and polarization

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Toll-Like Receptors

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Macrophage Diversity Enhances Tumor Progression and Metastasis

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

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Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

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Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation

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Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21

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An Emerging Regulatory Role for the Tumor Microenvironment in the DNA Damage Response to Double-Strand Breaks

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Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy

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Immune-metabolic interactions between Leishmania and macrophage host

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Engineered drug delivery nanosystems for tumor microenvironment normalization therapy

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In Vitro Modeling of Atherosclerosis Using iPSC‐Derived Blood Vessel Organoids

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Alterations in the innate immune system due to exhausting exercise in intensively trained rats

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Nature-inspired allomelanin nanomedicine alleviates cardiac ischemia/reperfusion injury via scavenging free radicals and ameliorating myocardial microenvironment

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Ru single-atom nanozymes targeting ROS-ferroptosis pathways for enhanced endometrial regeneration in intrauterine adhesion therapy

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Macrophage immunomodulation: An indispensable tool to evaluate the performance of wound dressing biomaterials

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Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

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Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis

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ADPGK‐AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth

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Targeting Macrophage Polarization in Infectious Diseases: M1/M2 Functional Profiles, Immune Signaling and Microbial Virulence Factors

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Prominent Contribution of Hydrogen Peroxide to Intracellular Reactive Oxygen Species Generated upon Exposure to Naphthalene Secondary Organic Aerosols

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17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis

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Mitochondria in innate immunity signaling and its therapeutic implications in autoimmune diseases

Jiao, Y., Yan, Z., & Yang, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1160035 · Cited by 35

Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction

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MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation

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Softness enhanced macrophage-mediated therapy of inhaled apoptotic-cell-inspired nanosystems for acute lung injury

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Interaction of Iron Oxide Nanoparticles with Macrophages Is Influenced Distinctly by “Self” and “Non-Self” Biological Identities

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Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection

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Gut redox and microbiome: charting the roadmap to T-cell regulation

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Iron Oxide Nanoparticle Targeting Mechanism and its Application in Tumor Magnetic Resonance Imaging and Therapy

Wu, L., Wang, C., & Li, Y. (2022) · Nanomedicine · doi:10.2217/nnm-2022-0246 · Cited by 32

Antioxidant, antibacterial, and anti-inflammatory Periplaneta americana remnant chitosan/polysaccharide composite film: In vivo wound healing application evaluation

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Effect of Zr Addition on the Corrosion of Ti in Acidic and Reactive Oxygen Species (ROS)-Containing Environments

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Pro-inflammatory macrophage polarization enhances the anti-cancer efficacy of self-assembled galactomannan nanoparticles entrapped with hydrazinocurcumin

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Saccorhiza polyschides used to synthesize gold and silver nanoparticles with enhanced antiproliferative and immunostimulant activity

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Advances in immunomodulatory MOFs for biomedical applications

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Loss of CD36 protects against diet‐induced obesity but results in impaired muscle stem cell function, delayed muscle regeneration and hepatic steatosis

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To regenerate or not to regenerate: Vertebrate model organisms of regeneration‐competency and ‐incompetency

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Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression

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Neuroimmune modulating and energy supporting nanozyme-mimic scaffold synergistically promotes axon regeneration after spinal cord injury

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Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet

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Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions

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Safety and efficacy of a COVID‑19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open‑label, controlled trial

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The Framingham Study on Cardiovascular Disease Risk and Stress-Defenses: A Historical Review

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Layer‐by‐Layer Cerium Oxide Nanoparticle Coating for Antioxidant Protection of Encapsulated Beta Cells

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Pro- and anti-oxidant properties of near-infrared (NIR) light responsive carbon nanoparticles

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Are Skeletal Muscle Changes during Prolonged Space Flights Similar to Those Experienced by Frail and Sarcopenic Older Adults?

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Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood–Spinal Cord Barrier Repair Following Spinal Cord Injury

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D‐series Resolvins activate Phospholipase D in phagocytes during inflammation and resolution

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Benefits in the Macrophage Response Due to Graphene Oxide Reduction by Thermal Treatment

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Higher Oxidative Stress in Endometriotic Lesions Upregulates Senescence-Associated p16ink4a and β-Galactosidase in Stromal Cells

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AMPK is essential for IL-10 expression and for maintaining balance between inflammatory and cytoprotective signaling

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The Macrophage Responses during Diabetic Oral Ulcer Healing by Liquid Coconut Shell Smoke: An Immunohistochemical Analysis

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Multifunctional Nanosystems Powered Photodynamic Immunotherapy

Ma, Y., Xiao, F., Lu, C., & Wen, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.905078 · Cited by 27

Dealing with Macrophage Plasticity to Address Therapeutic Challenges in Head and Neck Cancers

Furgiuele, S., Descamps, G., Cascarano, L., Boucq, A., Dubois, C., Journé, F., & Saussez, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126385 · Cited by 31

Nanotechnology Applications in Breast Cancer Immunotherapy

Wang, R., Kumar, P., Reda, M. M., Wallstrum, A., Crumrine, N. A., Ngamcherdtrakul, W., & Yantasee, W. (2023) · Small · doi:10.1002/smll.202308639 · Cited by 30

Molecular mechanisms of silver nanoparticle-induced neurotoxic injury and new perspectives for its neurotoxicity studies: A critical review

Yang, H., Niu, S., Guo, M., & Xue, Y. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.124934 · Cited by 26

Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages

Duchesne, C., Frescaline, N., Blaise, O., Lataillade, J., Banzet, S., Dussurget, O., & Rousseau, A. (2021) · mSphere · doi:10.1128/msphere.00217-21 · Cited by 26

Modulation of Macrophage Activity by Pulsed Electromagnetic Fields in the Context of Fracture Healing

Chen, Y., Menger, M. M., Braun, B. J., Schweizer, S., Linnemann, C., Falldorf, K., Ronniger, M., Wang, H., Histing, T., Nussler, A. K., et al. (2021) · Bioengineering · doi:10.3390/bioengineering8110167 · Cited by 26

Advances in Immunotherapy and the TGF-β Resistance Pathway in Metastatic Bladder Cancer

Benjamin, D. J., & Lyou, Y. (2021) · Cancers · doi:10.3390/cancers13225724 · Cited by 27

Bimetallic ions-doped carbon dots nanotheranostics for imaging-guided macrophage polarization/ROS scavenging in acute pancreatitis

Jing, F., Zhu, Y., Li, F., Wang, Y., Yu, X., Zhang, K., Xin, G., & Huang, W. Q. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.142675 · Cited by 26

Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies

Gong, A. G. W., Duan, R., Wang, H., Dong, T. T.-X., & Tsim, K. W. K. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00036 · Cited by 26

PARP1-LSD1 functional interplay controls transcription of SOD2 that protects human pro-inflammatory macrophages from death under an oxidative condition

Tokarz, P., Płoszaj, T., Regdon, Z., Virág, L., & Robaszkiewicz, A. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.12.004 · Cited by 26

Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration

Kim, M., Wang, X., Li, Y., Lin, Z., Collins, C. P., Liu, Y., Ahn, Y., Tsal, H.-M., Song, J. W., Duan, C., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.07.029 · Cited by 25

Environmental Factors That Contribute to the Maintenance of Cryptococcus neoformans Pathogenesis

Maliehe, M., Ntoi, M. A., Lahiri, S., Folorunso, O. S., Ogundeji, A. O., Pohl, C. H., & Sebolai, O. M. (2020) · Microorganisms · doi:10.3390/microorganisms8020180 · Cited by 32

Dietary supplementation with N‐3 polyunsaturated fatty acid‐enriched fish oil promotes wound healing after ultraviolet B‐induced sunburn in mice

Meng, F., Qiu, J., Chen, H., Shi, X., Yin, M., Zhu, M., & Yang, G. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2330 · Cited by 26

A Self-Supplying H2O2 Modified Nanozyme-Loaded Hydrogel for Root Canal Biofilm Eradication

Song, J., Hong, L., Zou, X., Alshawwa, H., Zhao, Y., Zhao, H., Liu, X., Si, C., & Zhang, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710107 · Cited by 25

Inflammatory hallmarks in 6-OHDA- and LPS-induced Parkinson's disease in rats

OLİYNYK, Z., Rudyk, M. P., Dovbynchuk, T., Dziubenko, N., Tolstanova, G. M., & Skivka, L. M. (2023) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2023.100616 · Cited by 26

Proposal for pathogenesis-based treatment options to reduce calcium oxalate stone recurrence

Khan, S. R., & Canales, B. K. (2023) · Asian journal of urology · doi:10.1016/j.ajur.2023.01.008 · Cited by 25

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms

Sareila, O., Hagert, C., Kelkka, T., Linja, M., Xu, B., Kihlberg, J. O., & Holmdahl, R. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6981 · Cited by 25

Naringin-induced M2 macrophage polarization facilitates osteogenesis of BMSCs and improves cranial bone defect healing in rat

Liu, J., Li, F., Ouyang, Y., Su, Z., Chen, D., Liang, Z., Zhang, Z., Lin, R., Luo, T., & Guo, L. (2024) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2024.109890 · Cited by 25

Reducing Oxidative Stress-Mediated Alcoholic Liver Injury by Multiplexed RNAi of Cyp2e1, Cyp4a10, and Cyp4a14

Zhang, Q., Wu, S., Chen, Q., Zhang, Y., Zhang, C., Yin, R., Ouyang, Z., & Wei, Y. (2024) · Biomedicines · doi:10.3390/biomedicines12071505 · Cited by 25

A nucleoside-based supramolecular hydrogel integrating localized self-delivery and immunomodulation for periodontitis treatment

Shuai, F., Yin, Y., Yao, Y., Deng, L., Wen, Y., Zhao, H., & Han, X. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.123024 · Cited by 24

A Reduction in Inflammatory Macrophages May Contribute to Skin Cancer Chemoprevention by Nicotinamide

Minocha, R., Martin, A. J., Chen, A. C., Scolyer, R. A., Lyons, J. G., McKenzie, C. A., Madore, J., Halliday, G. M., & Damian, D. L. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.08.018 · Cited by 24

Cell‐specific immune‐modulation of cadmium on murine macrophages and mast cell lines in vitro

García‐Mendoza, D., Han, B., van den Berg, H. H. J., & van den Brink, N. W. (2019) · Journal of Applied Toxicology · doi:10.1002/jat.3788 · Cited by 24

Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease

Katkar, G. D., Sayed, I. M., Anandachar, M. S., Castillo, V., Vidales, E., Toobian, D., Usmani, F., Sawires, J. R., Leriche, G., Yang, J., et al. (2022) · Communications Biology · doi:10.1038/s42003-022-03168-4 · Cited by 24

Biology of macrophage fate decision: Implication in inflammatory disorders

Yadav, S., Dwivedi, A., & Tripathi, A. (2022) · Cell Biology International · doi:10.1002/cbin.11854 · Cited by 26

Macrophage Reprogramming via Targeted ROS Scavenging and COX-2 Downregulation for Alleviating Inflammation

Luo, X., Xiong, H., Jiang, Y., Fan, Y., Zuo, C., Chen, D., Chen, L., Lin, H., & Gao, J. (2023) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.3c00239 · Cited by 25

Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47phox

Sowrirajan, B., Saito, Y., Poudyal, D., Chen, Q., Sui, H., Ravin, S. S. D., Imamichi, H., Sato, T., Kuhns, D. B., Noguchi, N., et al. (2017) · Scientific Reports · doi:10.1038/srep43441 · Cited by 24

NADPH Oxidases in Neurodegenerative Disorders: Mechanisms and Therapeutic Opportunities

Fiadeiro, M. B., Diogo, J. C., Silva, A., Kim, Y., & Cristóvão, A. C. (2024) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0002 · Cited by 25

TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses

Sawoo, R., & Bishayi, B. (2024) · Immunobiology · doi:10.1016/j.imbio.2024.152840 · Cited by 27

A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment

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