Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily

Bootcov, M. R., Bauskin, A. R., Valenzuela, S. M., Moore, A. G., Bansal, M., He, X. Y., Zhang, H. P., Donnellan, M., Mahler, S. M., Pryor, K., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11514 · Cited by 1,180 · see citing works

Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α

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Large-Scale Delineation of Secreted Protein Biomarkers Overexpressed in Cancer Tissue and Serum

Welsh, J. B., Sapinoso, L. M., Kern, S. G., Brown, D. A., Liu, T., Bauskin, A. R., Ward, R. L., Hawkins, N. J., Quinn, D. I., Russell, P. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530278100 · Cited by 503 · see citing works

Cyclooxygenase Inhibitors Regulate the Expression of a TGF-β Superfamily Member That Has Proapoptotic and Antitumorigenic Activities

Baek, S. J., Kim, K. S., Nixon, J. B., Wilson, L. C., & Eling, T. E. (2001) · Molecular Pharmacology · doi:10.1124/mol.59.4.901 · Cited by 402 · see citing works

Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers

Koopmann, J., Buckhaults, P., Brown, D. A., ZAHURAK, M. L., Sato, N., Fukushima, N., Sokoll, L. J., Chan, D. W., Yeo, C. J., Hruban, R. H., et al. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0165 · Cited by 274 · see citing works

MIC-1 is a novel TGF-β superfamily cytokine associated with macrophage activation

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MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.

Brown, D. A., Ward, R. L., Buckhaults, P., Liu, T., Romans, K. E., Hawkins, N. J., Bauskin, A. R., Kinzler, K. W., Vogelstein, B., & Breit, S. N. (2003) · PubMed · Cited by 265 · see citing works

Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression

Li, P.-X., Wong, J., Ayed, A., Ngo, D., Brade, A. M., Arrowsmith, C., Austin, R. C., & Klamut, H. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909580199 · Cited by 254 · see citing works

Activin receptor–like kinase 1 is implicated in the maturation phase of angiogenesis

Lamouille, S., Mallet, C., Feige, J., & Bailly, S. (2002) · Blood · doi:10.1182/blood.v100.13.4495 · Cited by 211 · see citing works

Expression of a novel member of the TGF-β superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues

Bottner, M. B., Suter‐Crazzolara, C., Schober, A., & Unsicker, K. (1999) · Cell and Tissue Research · doi:10.1007/s004410051337 · Cited by 180 · see citing works

Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.

Liu, T., Bauskin, A. R., Zaunders, J. J., Brown, D. A., Pankhurst, S., Russell, P. J., Breit, S. N., & Panhurst, S. (2003) · PubMed · Cited by 174 · see citing works

Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1

Albertoni, M., Shaw, P., Nozaki, M., Godard, S., Tenan, M., Hamou, M., Fairlie, D. W., Breit, S., Paralkar, V., de Tribolet, N., et al. (2002) · Oncogene · doi:10.1038/sj.onc.1205610 · Cited by 173 · see citing works

Cyclooxygenase Inhibitors Induce the Expression of the Tumor Suppressor Gene EGR-1, Which Results in the Up-Regulation of NAG-1, an Antitumorigenic Protein

Baek, S. J., Kim, J., Moore, S. M., Lee, S., Martinez, J. M., & Eling, T. E. (2004) · Molecular Pharmacology · doi:10.1124/mol.104.005108 · Cited by 162 · see citing works

Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system.

Lee, D. H., Yang, Y. D., Lee, S. J., Kim, K. Y., Koo, T. H., Shin, S. M., Song, K. S., Lee, Y. H., Kim, Y. J., Lee, J. J., et al. (2003) · PubMed · Cited by 161 · see citing works

Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation.

Yang, H. S., Filipovic, Z., Brown, D. A., Breit, S. N., & Vassilev, L. T. (2003) · PubMed · Cited by 157 · see citing works

The Propeptide Mediates Formation of Stromal Stores of PROMIC-1: Role in Determining Prostate Cancer Outcome

Bauskin, A. R., Brown, D. A., Junankar, S. R., Rasiah, K., Eggleton, S. A., Hunter, M. I., Liu, T., Smith, D., Kuffner, T., Pankhurst, G. J., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3827 · Cited by 154 · see citing works

Expression of growth differentiation factor‐15/ macrophage inhibitory cytokine‐1 (GDF‐15/MIC‐1) in the perinatal, adult, and injured rat brain

Schober, A., Bottner, M. B., Strelau, J., Kinscherf, R., Bonaterra, G. A., Barth, M., Schilling, L., Fairlie, W. D., Breit, S. N., & Unsicker, K. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1333 · Cited by 151 · see citing works

H6D Polymorphism in Macrophage-Inhibitory Cytokine-1 Gene Associated With Prostate Cancer

Lindmark, F., Zheng, S. L., Wiklund, F. E., Bensen, J. T., Bälter, K. A., Chang, B., Hedelin, M., Clark, J., Stattin, P., Meyers, D. A., et al. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh227 · Cited by 120 · see citing works

Measurement of Serum Levels of Macrophage Inhibitory Cytokine 1 Combined with Prostate-Specific Antigen Improves Prostate Cancer Diagnosis

Brown, D. A., Stephan, C., Ward, R. L., Law, M. G., Hunter, M., Bauskin, A. R., Amin, J., Jung, K., Diamandis, E. P., Hampton, G. M., et al. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-05-1331 · Cited by 109 · see citing works

Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays

de Wit, N. J. W., Rijntjes, J., Diepstra, J. H. S., Kuppevelt, T. H. V., Weidle, U. H., Ruiter, D. J., & van Muijen, G. N. P. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602612 · Cited by 97 · see citing works

Protein Profiling of Microdissected Prostate Tissue Links Growth Differentiation Factor 15 to Prostate Carcinogenesis

Cheung, P. K., Woolcock, B. W., Adomat, H. H., Sutcliffe, M., Bainbridge, T. C., Jones, E. C., Webber, D. L., Κinahan, T. J., Sadar, M. D., Gleave, M. E., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1216 · Cited by 95 · see citing works

Identification of Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1) as a Novel Downstream Target of Phosphatidylinositol 3-Kinase/AKT/GSK-3β Pathway

Yamaguchi, K., Lee, S., Eling, T. E., & Baek, S. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408796200 · Cited by 94 · see citing works

Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues

Nakamura, T., Scorilas, A., Stephan, C., Yousef, G. M., Kristiansen, G., Jung, K., & Diamandis, E. P. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6600869 · Cited by 88 · see citing works

The Transforming Growth Factor-β Family Members Bone Morphogenetic Protein-2 and Macrophage Inhibitory Cytokine-1 as Mediators of the Antiangiogenic Activity of N-(4-Hydroxyphenyl)Retinamide

Ferrari, N., Pfeffer, U., Dell’Eva, R., Ambrosini, C., Noonan, D. M., & Albini, A. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2210 · Cited by 75 · see citing works

The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15

Kim, J., Baek, S. J., Sali, T. M., & Eling, T. E. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-04-0201 · Cited by 64 · see citing works

Immediate Gene Expression Changes After the First Course of Neoadjuvant Chemotherapy in Patients with Primary Breast Cancer Disease

Modlich, O., Prisack, H.-B., Munnes, M., Audretsch, W., & Bojar, H. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-1031 · Cited by 64 · see citing works

Autocrine Human Growth Hormone Inhibits Placental Transforming Growth Factor-β Gene Transcription to Prevent Apoptosis and Allow Cell Cycle Progression of Human Mammary Carcinoma Cells

Graichen, R., Liu, D., Sun, Y., Lee, K., & Lobie, P. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109931200 · Cited by 61 · see citing works

Pancreatic Cancer

Maitra, A., & Hruban, R. H. (2008) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.154305 · Cited by 707 · see citing works

Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1

Johnen, H., Lin, S., Kuffner, T., Brown, D. A., Tsai, V. W.-W., Bauskin, A. R., Wu, L., Pankhurst, G., Jiang, L., Junankar, S., et al. (2007) · Nature Medicine · doi:10.1038/nm1677 · Cited by 612 · see citing works

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

Riker, A. I., Enkemann, S. A., Fodstad, Ø., Liu, S., Ren, S., Morris, C. G., Xi, Y., Howell, P., Metge, B. J., Samant, R. S., et al. (2008) · BMC Medical Genomics · doi:10.1186/1755-8794-1-13 · Cited by 527 · see citing works

GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective

Adela, R., & Banerjee, S. K. (2015) · Journal of Diabetes Research · doi:10.1155/2015/490842 · Cited by 474 · see citing works

Promiscuity and specificity in BMP receptor activation

Mueller, T. D., & Nickel, J. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.02.043 · Cited by 285 · see citing works

Clinical tools and biomarkers to predict preeclampsia

MacDonald, T. M., Walker, S. P., Hannan, N. J., Tong, S., & Kaitu’u‐Lino, T. J. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103780 · Cited by 335 · see citing works

Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality

Wiklund, F. E., Bennet, A. M., Magnusson, P. K. E., Eriksson, U. K., Lindmark, F., Wu, L., Yaghoutyfam, N., Marquis, C. P., Stattin, P. E., Pedersen, N. L., et al. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00629.x · Cited by 290 · see citing works

Circulating Concentrations of Growth-Differentiation Factor 15 in Apparently Healthy Elderly Individuals and Patients with Chronic Heart Failure as Assessed by a New Immunoradiometric Sandwich Assay

Kempf, T., Horn-Wichmann, R., Brabant, G. E., Peter, T., Allhoff, T., Klein, G. G., Drexler, H., Johnston, N., Wallentin, L. C., & Wollert, K. C. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.076828 · Cited by 286 · see citing works

The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1

Unsicker, K., Spittau, B., & KRIEGLSTEIN, K. G. (2013) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2013.05.003 · Cited by 274 · see citing works

GDF15 induces anorexia through nausea and emesis

Borner, T., Shaulson, E. D., Ghidewon, M. Y., Barnett, A. B., Horn, C. C., Doyle, R. P., Grill, H. J., Hayes, M. R., & De Jonghe, B. C. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.12.004 · Cited by 255 · see citing works

Hepatokines and metabolism: Deciphering communication from the liver

Jensen-Cody, S. O., & Potthoff, M. J. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101138 · Cited by 252 · see citing works

Growth-Differentiation Factor-15 Is a Robust, Independent Predictor of 11-Year Mortality Risk in Community-Dwelling Older Adults

Daniels, L. B., Clopton, P., Laughlin, G. A., Maisel, A. S., & Barrett-Connor, E. L. (2011) · Circulation · doi:10.1161/circulationaha.110.979740 · Cited by 248 · see citing works

The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism

Breit, S. N., Johnen, H., Cook, A. D., Tsai, V. W. W., Mohammad, M. G., Kuffner, T., Zhang, H. P., Marquis, C. P., Jiang, L., Lockwood, G., et al. (2011) · Growth Factors · doi:10.3109/08977194.2011.607137 · Cited by 247 · see citing works

Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine‐1 in cancer

Mimeault, M., & Batra, S. K. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22196 · Cited by 208 · see citing works

Growth differentiation factor 15 (GDF15): a survival protein with therapeutic potential in metabolic diseases

Baek, S. J., & Eling, T. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.02.008 · Cited by 194 · see citing works

Identification of Macrophage Inhibitory Cytokine-1 in Adipose Tissue and Its Secretion as an Adipokine by Human Adipocytes

Ding, Q., Mráček, T., González‐Muniesa, P., Kos, K., Wilding, J. P. H., Trayhurn, P., & Chen, B. (2008) · Endocrinology · doi:10.1210/en.2008-0952 · Cited by 193 · see citing works

TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator

Tsai, V. W.-W., Macia, L., Johnen, H., Kuffner, T., Manadhar, R., Jørgensen, S. B., Lee-Ng, K. K. M., Zhang, H. P., Wu, L., Marquis, C. P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055174 · Cited by 188 · see citing works

Growth Differentiation Factor-15 for Prognostic Assessment of Patients with Acute Pulmonary Embolism

Lankeit, M., Kempf, T., Dellas, C., Cuny, M., Tapken, H., Peter, T., Olschewski, M., Konstantinides, S., & Wollert, K. C. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200712-1786oc · Cited by 188 · see citing works

Exercise increases circulating GDF15 in humans

Kleinert, M., Clemmensen, C., Sjøberg, K. A., Carl, C. S., Jeppesen, J. F., Wojtaszewski, J. F. P., Kiens, B., & Richter, E. A. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2017.12.016 · Cited by 186 · see citing works

Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia

Siddiqui, J. A., Pothuraju, R., Κhan, P., Sharma, G., Muniyan, S., Seshacharyulu, P., Jain, M., Nasser, M. W., & Batra, S. K. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.11.002 · Cited by 182 · see citing works

NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

Ratnam, N. M., Peterson, J. M., Talbert, E. E., Ladner, K. J., Rajasekera, P. V., Schmidt, C. R., Dillhoff, M. E., Swanson, B. J., Haverick, E. N., Kladney, R. D., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci91561 · Cited by 176 · see citing works

Effects of Low-Dose Radiation on the Immune System of Mice after Total-Body Irradiation

Bogdándi, E. N., Balogh, A., Felgyinszki, N., Szatmári, T., Persa, E., Hildebrandt, G., Sáfrány, G., & Lumniczky, K. (2010) · Radiation Research · doi:10.1667/rr2160.1 · Cited by 171 · see citing works

Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach

Xue, H., Lü, B., Zhang, J., Wu, M., Huang, Q., Wu, Q., Sheng, H., Wu, D., Hu, J., & Lai, M. (2009) · Journal of Proteome Research · doi:10.1021/pr9008817 · Cited by 169 · see citing works

The Novel Biomarker Growth Differentiation Factor 15 in Heart Failure with Normal Ejection Fraction

Stahrenberg, R., Edelmann, F., Mende, M., Kockskämper, A., Düngen, H., Lüers, C., Binder, L., Herrmann‐Lingen, C., Gelbrich, G., Hasenfuss, G. P., et al. (2010) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfq151 · Cited by 161 · see citing works

Novel biomarkers in cardiovascular disease: Update 2010

Hochholzer, W., Morrow, D. A., & Giugliano, R. P. (2010) · American Heart Journal · doi:10.1016/j.ahj.2010.06.010 · Cited by 155 · see citing works

Macrophage Inhibitory Cytokine 1: A New Prognostic Marker in Prostate Cancer

Brown, D. A., Lindmark, F., Stattin, P. E., Bälter, K. A., Adami, H., Zheng, S. L., Xu, J., Isaacs, W. B., Grönberg, H., Breit, S. N., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-3126 · Cited by 152 · see citing works

Growth differentiation factor 15 in erythroid health and disease

Tanno, T., Noel, P., & Miller, J. L. (2010) · Current Opinion in Hematology · doi:10.1097/moh.0b013e328337b52f · Cited by 139 · see citing works

Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15

Guo, Y., Ayers, J. L., Carter, K. T., Wang, T., Maden, S. K., Edmond, D., Newcomb P, P., Li, C., Ulrich, C., Yu, M., et al. (2019) · Aging Cell · doi:10.1111/acel.13013 · Cited by 139 · see citing works

Inflammation as a Driver of Prostate Cancer Metastasis and Therapeutic Resistance

Archer, M., Dogra, N., & Kyprianou, N. (2020) · Cancers · doi:10.3390/cancers12102984 · Cited by 140 · see citing works

Clinical and Genetic Correlates of Growth Differentiation Factor 15 in the Community

Ho, J. E., Mahajan, A., Chen, M., Larson, M. G., McCabe, E. L., Ghorbani, A., Cheng, S. C., Johnson, A. D., Lindgren, C. M., Kempf, T., et al. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2012.190322 · Cited by 133 · see citing works

Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR

Scrideli, C. A., Carlotti, C. G., Okamoto, O. K., Andrade, V. D. S. S., Cortez, M. A., Motta, F., Lucio-Eterovic, A. K., Neder, L., Rosemberg, S., Oba‐Shinjo, S. M., et al. (2008) · Journal of Neuro-Oncology · doi:10.1007/s11060-008-9579-4 · Cited by 129 · see citing works

Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15

Bruzzese, F., Hägglöf, C., Leone, A., Sjöberg, E., Roca, M. S., Kiflemariam, S., Sjöblom, T., Hammarsten, P., Egevad, L., Bergh, A., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-2259 · Cited by 127 · see citing works

Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond

Mullican, S. E., & Rangwala, S. M. (2018) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2018.05.002 · Cited by 127 · see citing works

The Anorectic Actions of the TGFβ Cytokine MIC-1/GDF15 Require an Intact Brainstem Area Postrema and Nucleus of the Solitary Tract

Tsai, V. W.-W., Manandhar, R., Jørgensen, S. B., Lee-Ng, K. K. M., Zhang, H. P., Marquis, C. P., Jiang, L., Husaini, Y., Lin, S., Sainsbury, A., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100370 · Cited by 124 · see citing works

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells

Kim, K.-K., Lee, J. J., Yang, Y. D., You, K., & Lee, J. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn031 · Cited by 116 · see citing works

Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer

Staff, A. C., Bock, A. J., Becker, C., Kempf, T., Wollert, K. C., & Davidson, B. (2010) · Gynecologic Oncology · doi:10.1016/j.ygyno.2010.05.032 · Cited by 115 · see citing works

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma

Wang, X., Li, Y., Tian, H.-M., Qi, J., Li, M., Fu, C., Wu, F., Wang, Y., Cheng, D., Zhao, W., et al. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-578 · Cited by 111 · see citing works

Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease

Breit, S. N., Carrero, J. J., Tsai, V. W.-W., Yagoutifam, N., Luo, W., Kuffner, T., Bauskin, A. R., Wu, L., Jiang, L., Barany, P. F., et al. (2011) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfr575 · Cited by 111 · see citing works

Adaptive Induction of Growth Differentiation Factor 15 Attenuates Endothelial Cell Apoptosis in Response to High Glucose Stimulus

Li, J., Yang, L., Qin, W., Zhang, G., Yuan, J., & Wang, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065549 · Cited by 110 · see citing works

hnRNP A2/B1 Modulates Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines

Tauler, J., Zudaire, E., Liu, H., Shih, J. H., & Mulshine, J. L. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0860 · Cited by 110 · see citing works

Unique features of the transcriptional response to model aneuploidy in human cells

Dürrbaum, M., Kuznetsova, A. Y., Passerini, V., Stingele, S., Stoehr, G., & Štorchová, Z. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-139 · Cited by 110 · see citing works

Anorexia–cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15

Tsai, V. W.-W., Lin, S., Brown, D. A., Sainsbury, A., & Breit, S. N. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.242 · Cited by 108 · see citing works

Association of Serum Level of Growth Differentiation Factor 15 with Liver Cirrhosis and Hepatocellular Carcinoma

Liu, X., Chi, X., Gong, Q., Gao, L., Niu, Y., Chi, X., Cheng, M., Si, Y., Wang, M., Zhong, J., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127518 · Cited by 108 · see citing works

Macrophage Inhibitory Cytokine-1 Is Overexpressed in Malignant Melanoma and Is Associated with Tumorigenicity

Boyle, G. M., Pedley, J., Martyn, A. C., Banducci, K., Strutton, G., Brown, D. A., Breit, S. N., & Parsons, P. G. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.270 · Cited by 108 · see citing works

Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline - the Sydney Memory and Aging Study

Fuchs, T. L., Trollor, J. N., Crawford, J., Brown, D. A., Baune, B. T., Samaras, K., Campbell, L. V., Breit, S. N., Brodaty, H., Sachdev, P. S., et al. (2013) · Aging Cell · doi:10.1111/acel.12116 · Cited by 104 · see citing works

Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling

Zhao, L., Lee, B. Y., Brown, D. A., Molloy, M. P., Marx, G. M., Pavlakis, N., Boyer, M. J., Stockler, M. R., Kaplan, W. H., Breit, S. N., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4901 · Cited by 104 · see citing works

Bioactivity and Prognostic Significance of Growth Differentiation Factor GDF15 Secreted by Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma

Corre, J., Labat, E., Espagnolle, N., Hébraud, B., Avet‐Loiseau, H., Roussel, M., Huynh, A., Gadelorge, M., Cordelier, P., Klein, B., et al. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-0188 · Cited by 103 · see citing works

GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss

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Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity

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