The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Role of Macrophage Inhibitory Cytokine-1 in Tumorigenesis and Diagnosis of Cancer
Open accessAbstract
Macrophage inhibitory cytokine-1 (MIC-1), a transforming growth factor-beta superfamily cytokine, is involved in tumor pathogenesis, and its measurement can be used as a clinical tool for the diagnosis and management of a wide range of cancers. Although generally considered to be part of the cell's antitumorigenic repertoire, MIC-1 secretion, processing, and latent storage suggest a complex, dynamic variability in MIC-1 bioavailability in the tumor microenvironment, potentially modulating tumor progression and invasiveness.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Growth differentiation factor 15 (GDF15), also called macrophage inhibitory cytokine-1, is associated with numerous biological processes and diseases including cancer, cardiovascular disease, and obesity [[199], [200], [201], [202]].”
From Hepatokines and metabolism: Deciphering communication from the liver (2021) · cites this paper as [199]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily
Bootcov, M. R., Bauskin, A. R., Valenzuela, S. M., Moore, A. G., Bansal, M., He, X. Y., Zhang, H. P., Donnellan, M., Mahler, S. M., Pryor, K., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11514 · Cited by 1,180
Self-citationPhosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α
Campbell, R., Bhat-Nakshatri, P., Patel, N., Constantinidou, D., Ali, S., & Nakshatri, H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010840200 · Cited by 880
Large-Scale Delineation of Secreted Protein Biomarkers Overexpressed in Cancer Tissue and Serum
Welsh, J. B., Sapinoso, L. M., Kern, S. G., Brown, D. A., Liu, T., Bauskin, A. R., Ward, R. L., Hawkins, N. J., Quinn, D. I., Russell, P. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530278100 · Cited by 503
Self-citationBaek, S. J., Kim, K. S., Nixon, J. B., Wilson, L. C., & Eling, T. E. (2001) · Molecular Pharmacology · doi:10.1124/mol.59.4.901 · Cited by 402
Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers
Koopmann, J., Buckhaults, P., Brown, D. A., ZAHURAK, M. L., Sato, N., Fukushima, N., Sokoll, L. J., Chan, D. W., Yeo, C. J., Hruban, R. H., et al. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0165 · Cited by 274
Self-citationMIC-1 is a novel TGF-β superfamily cytokine associated with macrophage activation
Fairlie, W. D., Moore, A. G., Bauskin, A. R., Russell, P. K., Zhang, H.-P., & Breit, S. N. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.65.1.2 · Cited by 266
Self-citationMIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.
Brown, D. A., Ward, R. L., Buckhaults, P., Liu, T., Romans, K. E., Hawkins, N. J., Bauskin, A. R., Kinzler, K. W., Vogelstein, B., & Breit, S. N. (2003) · PubMed · Cited by 265
Self-citationLi, P.-X., Wong, J., Ayed, A., Ngo, D., Brade, A. M., Arrowsmith, C., Austin, R. C., & Klamut, H. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909580199 · Cited by 254
Activin receptor–like kinase 1 is implicated in the maturation phase of angiogenesis
Lamouille, S., Mallet, C., Feige, J., & Bailly, S. (2002) · Blood · doi:10.1182/blood.v100.13.4495 · Cited by 211
Albertoni, M., Shaw, P. H., Nozaki, M., Godard, S., Tenan, M., Hamou, M., Fairlie, W. D., Breit, S. N., Paralkar, V. M., de Tribolet, N., et al. (2002) · Oncogene · doi:10.1038/sj.onc.1205610 · Cited by 180
Self-citation
Research works printed but not linked: 1
- Liu T, Bauskin AR, Zaunders J, et al. MIC-1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Res 2003; 63: 5034–40.
Cited by
Sorted by citations
Maitra, A., & Hruban, R. H. (2008) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.154305 · Cited by 707
Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
Johnen, H., Lin, S., Kuffner, T., Brown, D. A., Tsai, V. W.-W., Bauskin, A. R., Wu, L., Pankhurst, G., Jiang, L., Junankar, S., et al. (2007) · Nature Medicine · doi:10.1038/nm1677 · Cited by 612
Self-citationRiker, A. I., Enkemann, S. A., Fodstad, Ø., Liu, S., Ren, S., Morris, C. G., Xi, Y., Howell, P., Metge, B. J., Samant, R. S., et al. (2008) · BMC Medical Genomics · doi:10.1186/1755-8794-1-13 · Cited by 525
Adela, R., & Banerjee, S. K. (2015) · Journal of Diabetes Research · doi:10.1155/2015/490842 · Cited by 474
Promiscuity and specificity in BMP receptor activation
Mueller, T. D., & Nickel, J. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.02.043 · Cited by 302
Clinical tools and biomarkers to predict preeclampsia
MacDonald, T. M., Walker, S. P., Hannan, N. J., Tong, S., & Kaitu’u‐Lino, T. J. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103780 · Cited by 335
Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality
Wiklund, F. E., Bennet, A. M., Magnusson, P. K. E., Eriksson, U. K., Lindmark, F., Wu, L., Yaghoutyfam, N., Marquis, C. P., Stattin, P. E., Pedersen, N. L., et al. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00629.x · Cited by 293
Self-citationKempf, T., Horn-Wichmann, R., Brabant, G. E., Peter, T., Allhoff, T., Klein, G. G., Drexler, H., Johnston, N., Wallentin, L. C., & Wollert, K. C. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.076828 · Cited by 290
Unsicker, K., Spittau, B., & KRIEGLSTEIN, K. G. (2013) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2013.05.003 · Cited by 279
GDF15 induces anorexia through nausea and emesis
Borner, T., Shaulson, E. D., Ghidewon, M. Y., Barnett, A. B., Horn, C. C., Doyle, R. P., Grill, H. J., Hayes, M. R., & De Jonghe, B. C. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.12.004 · Cited by 255
Hepatokines and metabolism: Deciphering communication from the liver
Jensen-Cody, S. O., & Potthoff, M. J. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101138 · Cited by 252
Daniels, L. B., Clopton, P., Laughlin, G. A., Maisel, A. S., & Barrett-Connor, E. L. (2011) · Circulation · doi:10.1161/circulationaha.110.979740 · Cited by 246
Breit, S. N., Johnen, H., Cook, A. D., Tsai, V. W. W., Mohammad, M. G., Kuffner, T., Zhang, H. P., Marquis, C. P., Jiang, L., Lockwood, G., et al. (2011) · Growth Factors · doi:10.3109/08977194.2011.607137 · Cited by 247
Self-citationMimeault, M., & Batra, S. K. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22196 · Cited by 211
Baek, S. J., & Eling, T. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.02.008 · Cited by 194
Ding, Q., Mráček, T., González‐Muniesa, P., Kos, K., Wilding, J. P. H., Trayhurn, P., & Chen, B. (2008) · Endocrinology · doi:10.1210/en.2008-0952 · Cited by 200
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator
Tsai, V. W.-W., Macia, L., Johnen, H., Kuffner, T., Manadhar, R., Jørgensen, S. B., Lee-Ng, K. K. M., Zhang, H. P., Wu, L., Marquis, C. P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055174 · Cited by 188
Self-citationGrowth Differentiation Factor-15 for Prognostic Assessment of Patients with Acute Pulmonary Embolism
Lankeit, M., Kempf, T., Dellas, C., Cuny, M., Tapken, H., Peter, T., Olschewski, M., Konstantinides, S., & Wollert, K. C. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200712-1786oc · Cited by 183
Exercise increases circulating GDF15 in humans
Kleinert, M., Clemmensen, C., Sjøberg, K. A., Carl, C. S., Jeppesen, J. F., Wojtaszewski, J. F. P., Kiens, B., & Richter, E. A. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2017.12.016 · Cited by 195
Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia
Siddiqui, J. A., Pothuraju, R., Κhan, P., Sharma, G., Muniyan, S., Seshacharyulu, P., Jain, M., Nasser, M. W., & Batra, S. K. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.11.002 · Cited by 187
NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development
Ratnam, N. M., Peterson, J. M., Talbert, E. E., Ladner, K. J., Rajasekera, P. V., Schmidt, C. R., Dillhoff, M. E., Swanson, B. J., Haverick, E. N., Kladney, R. D., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci91561 · Cited by 173
Effects of Low-Dose Radiation on the Immune System of Mice after Total-Body Irradiation
Bogdándi, E. N., Balogh, A., Felgyinszki, N., Szatmári, T., Persa, E., Hildebrandt, G., Sáfrány, G., & Lumniczky, K. (2010) · Radiation Research · doi:10.1667/rr2160.1 · Cited by 171
Xue, H., Lü, B., Zhang, J., Wu, M., Huang, Q., Wu, Q., Sheng, H., Wu, D., Hu, J., & Lai, M. (2009) · Journal of Proteome Research · doi:10.1021/pr9008817 · Cited by 167
The Novel Biomarker Growth Differentiation Factor 15 in Heart Failure with Normal Ejection Fraction
Stahrenberg, R., Edelmann, F., Mende, M., Kockskämper, A., Düngen, H., Lüers, C., Binder, L., Herrmann‐Lingen, C., Gelbrich, G., Hasenfuss, G. P., et al. (2010) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfq151 · Cited by 167
Novel biomarkers in cardiovascular disease: Update 2010
Hochholzer, W., Morrow, D. A., & Giugliano, R. P. (2010) · American Heart Journal · doi:10.1016/j.ahj.2010.06.010 · Cited by 161
Macrophage Inhibitory Cytokine 1: A New Prognostic Marker in Prostate Cancer
Brown, D. A., Lindmark, F., Stattin, P. E., Bälter, K. A., Adami, H., Zheng, S. L., Xu, J., Isaacs, W. B., Grönberg, H., Breit, S. N., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-3126 · Cited by 152
Self-citationGrowth differentiation factor 15 in erythroid health and disease
Tanno, T., Noel, P., & Miller, J. L. (2010) · Current Opinion in Hematology · doi:10.1097/moh.0b013e328337b52f · Cited by 139
Guo, Y., Ayers, J. L., Carter, K. T., Wang, T., Maden, S. K., Edmond, D., Newcomb P, P., Li, C., Ulrich, C., Yu, M., et al. (2019) · Aging Cell · doi:10.1111/acel.13013 · Cited by 139
Inflammation as a Driver of Prostate Cancer Metastasis and Therapeutic Resistance
Archer, M., Dogra, N., & Kyprianou, N. (2020) · Cancers · doi:10.3390/cancers12102984 · Cited by 144
Clinical and Genetic Correlates of Growth Differentiation Factor 15 in the Community
Ho, J. E., Mahajan, A., Chen, M., Larson, M. G., McCabe, E. L., Ghorbani, A., Cheng, S. C., Johnson, A. D., Lindgren, C. M., Kempf, T., et al. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2012.190322 · Cited by 133
Scrideli, C. A., Carlotti, C. G., Okamoto, O. K., Andrade, V. D. S. S., Cortez, M. A., Motta, F., Lucio-Eterovic, A. K., Neder, L., Rosemberg, S., Oba‐Shinjo, S. M., et al. (2008) · Journal of Neuro-Oncology · doi:10.1007/s11060-008-9579-4 · Cited by 129
Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Bruzzese, F., Hägglöf, C., Leone, A., Sjöberg, E., Roca, M. S., Kiflemariam, S., Sjöblom, T., Hammarsten, P., Egevad, L., Bergh, A., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-2259 · Cited by 127
Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond
Mullican, S. E., & Rangwala, S. M. (2018) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2018.05.002 · Cited by 127
Tsai, V. W.-W., Manandhar, R., Jørgensen, S. B., Lee-Ng, K. K. M., Zhang, H. P., Marquis, C. P., Jiang, L., Husaini, Y., Lin, S., Sainsbury, A., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100370 · Cited by 129
Self-citationKim, K.-K., Lee, J. J., Yang, Y. D., You, K., & Lee, J. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn031 · Cited by 119
Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer
Staff, A. C., Bock, A. J., Becker, C., Kempf, T., Wollert, K. C., & Davidson, B. (2010) · Gynecologic Oncology · doi:10.1016/j.ygyno.2010.05.032 · Cited by 115
Wang, X., Li, Y., Tian, H.-M., Qi, J., Li, M., Fu, C., Wu, F., Wang, Y., Cheng, D., Zhao, W., et al. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-578 · Cited by 111
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease
Breit, S. N., Carrero, J. J., Tsai, V. W.-W., Yagoutifam, N., Luo, W., Kuffner, T., Bauskin, A. R., Wu, L., Jiang, L., Barany, P. F., et al. (2011) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfr575 · Cited by 112
Self-citationLi, J., Yang, L., Qin, W., Zhang, G., Yuan, J., & Wang, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065549 · Cited by 110
hnRNP A2/B1 Modulates Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines
Tauler, J., Zudaire, E., Liu, H., Shih, J. H., & Mulshine, J. L. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0860 · Cited by 110
Unique features of the transcriptional response to model aneuploidy in human cells
Dürrbaum, M., Kuznetsova, A. Y., Passerini, V., Stingele, S., Stoehr, G., & Štorchová, Z. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-139 · Cited by 110
Tsai, V. W.-W., Lin, S., Brown, D. A., Salis, A., & Breit, S. N. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.242 · Cited by 109
Self-citationLiu, X., Chi, X., Gong, Q., Gao, L., Niu, Y., Chi, X., Cheng, M., Si, Y., Wang, M., Zhong, J., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127518 · Cited by 108
Boyle, G. M., Pedley, J., Martyn, A. C., Banducci, K., Strutton, G., Brown, D. A., Breit, S. N., & Parsons, P. G. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.270 · Cited by 109
Self-citationFuchs, T. L., Trollor, J. N., Crawford, J., Brown, D. A., Baune, B. T., Samaras, K., Campbell, L. V., Breit, S. N., Brodaty, H., Sachdev, P. S., et al. (2013) · Aging Cell · doi:10.1111/acel.12116 · Cited by 106
Self-citationIdentification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
Zhao, L., Lee, B. Y., Brown, D. A., Molloy, M. P., Marx, G. M., Pavlakis, N., Boyer, M. J., Stockler, M. R., Kaplan, W. H., Breit, S. N., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4901 · Cited by 105
Self-citationCorre, J., Labat, E., Espagnolle, N., Hébraud, B., Avet‐Loiseau, H., Roussel, M., Huynh, A., Gadelorge, M., Cordelier, P., Klein, B., et al. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-0188 · Cited by 106
GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss
Borner, T., Wald, H. S., Ghidewon, M. Y., Zhang, B., Wu, Z., Jonghe, B. C. D., Breen, D. M., & Grill, H. J. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107543 · Cited by 101
Tsai, V. W.-W., Zhang, H. P., Manandhar, R., Lee-Ng, K. K. M., Lebhar, H., Marquis, C. P., Husaini, Y., Sainsbury, A., Brown, D. A., & Breit, S. N. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.258 · Cited by 104
Self-citationShnaper, S., Desbaillets, I., Brown, D. A., Murat, A., Migliavacca, E., Schluep, M., Ostermann, S., Hamou, M., Stupp, R., Breit, S. N., et al. (2009) · International Journal of Cancer · doi:10.1002/ijc.24639 · Cited by 100
Self-citationBrown, D. A., Moore, J. J., Johnen, H., Smeets, T. J. M., Bauskin, A. R., Kuffner, T., Weedon, H., Milliken, S. T., Tak, P. P., Smith, M., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22410 · Cited by 99
Self-citationA Prospective Study of Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) and Risk of Colorectal Cancer
Mehta, R. S., Song, M., Bezawada, N., Wu, K., García‐Albéniz, X., Morikawa, T., Fuchs, C. S., Ogino, S., Giovannucci, E. L., & Chan, A. T. (2014) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju016 · Cited by 98
Ramirez, J., Schaad, O., Durual, S., Cossali, D., Docquier, M., Beris, P., Descombes, P., & Matthes, T. (2009) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07441.x · Cited by 96
Tsai, V. W.-W., Macia, L., Feinle‐Bisset, C., Manandhar, R., Astrup, A. V., Raben, A., Lorenzen, J. K., Schmidt, P. T., Wiklund, F. E., Pedersen, N. L., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133362 · Cited by 96
Self-citationWorth, A. A., Shoop, R., Tye, K., Feetham, C. H., D’Agostino, G., Dodd, G. T., Reimann, F. M., Gribble, F. M., Beebe, E., Dunbar, J. D., et al. (2020) · eLife · doi:10.7554/elife.55164 · Cited by 92
Pathways of chemotherapy resistance in castration-resistant prostate cancer
Mahon, K. L., Henshall, S. M., Sutherland, R. L., & Horvath, L. G. (2011) · Endocrine Related Cancer · doi:10.1530/erc-10-0343 · Cited by 89
Systemic effects of mitochondrial stress
Bar‐Ziv, R., Bolas, T., & Dillin, A. G. (2020) · EMBO Reports · doi:10.15252/embr.202050094 · Cited by 86
Growth differentiation factor 15 in cardiovascular diseases: from bench to bedside
Xu, X., Li, Z., & Gao, W. D. (2011) · Biomarkers · doi:10.3109/1354750x.2011.580006 · Cited by 86
Johnen, H., Kuffner, T., Brown, D. A., Wu, B. J., Stocker, R., & Breit, S. N. (2012) · Cardiovascular Pathology · doi:10.1016/j.carpath.2012.02.003 · Cited by 86
Self-citationTanno, T., Lim, Y., Wang, Q., Chesi, M., Bergsagel, P. L., Matthews, G., Johnstone, R. W., Ghosh, N., Borrello, I., Huff, C. A., et al. (2013) · Blood · doi:10.1182/blood-2013-08-524025 · Cited by 82
Anorexia/cachexia of chronic diseases: a role for the TGF‐β family cytokine MIC‐1/GDF15
Tsai, V. W.-W., Husaini, Y., Manandhar, R., Lee-Ng, K. K. M., Zhang, H. P., Harriott, K., Jiang, L., Lin, S., Sainsbury, A., Brown, D. A., et al. (2012) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-012-0082-6 · Cited by 86
Self-citationGrowth-Differentiation Factor-15 in Heart Failure
Kempf, T., & Wollert, K. C. (2009) · Heart Failure Clinics · doi:10.1016/j.hfc.2009.04.006 · Cited by 81
Staff, A. C., Trovik, J., Zahl, E. A. G., Wik, E., Wollert, K. C., Kempf, T., & Salvesen, H. B. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-0715 · Cited by 77
The TGF-β Signalling Network in Muscle Development, Adaptation and Disease
Chen, J. L., Colgan, T. D., Walton, K. L., Gregorevic, P., & Harrison, C. A. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-27511-6_5 · Cited by 78
Growth/differentiation factor-15: prostate cancer suppressor or promoter?
Vaňhara, P., Hampl, A., Kozubík, A., & Souček, K. (2012) · Prostate Cancer and Prostatic Diseases · doi:10.1038/pcan.2012.6 · Cited by 67
Li, C., Wang, X., Casal, J. I., Wang, J., Li, P., Zhang, W., Xu, E., Lai, M., & Zhang, H. (2016) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12830 · Cited by 66
Discovery of biomarkers for endometrial cancer: current status and prospects
Rižner, T. L. (2016) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2016.1258302 · Cited by 68
GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer
Ahmed, D. S., Isnard, S., Lin, J. C.-Y., Routy, B., & Routy, J. (2020) · Journal of Cancer · doi:10.7150/jca.50376 · Cited by 71
Bauskin, A. R., Jiang, L., Luo, X., Wu, L., Brown, D. A., & Breit, S. N. (2010) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2009.0052 · Cited by 70
Self-citationYAP promotes breast cancer metastasis by repressing growth differentiation factor-15
Wang, T., Mao, B., Cheng, C., Zou, Z., Gao, J., Yang, Y., Lei, T., Qi, X., Yuan, Z., Xu, W., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.02.020 · Cited by 63
Huang, C.-Y., Beer, T. M., Higano, C. S., True, L. D., Vessella, R. L., Lange, P. H., Garzotto, M. G., & Nelson, P. S. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1037 · Cited by 66
Potentials of Plasma NGAL and MIC-1 as Biomarker(s) in the Diagnosis of Lethal Pancreatic Cancer
Kaur, S., Chakraborty, S., Baine, M. J., Mallya, K. B., Smith, L. M., Sasson, A. R., Brand, R. E., Guha, S., Jain, M., Wittel, U. A., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055171 · Cited by 64
From Inflammation to Prostate Cancer: The Role of Inflammasomes
Karan, D., & Dubey, S. (2016) · Advances in Urology · doi:10.1155/2016/3140372 · Cited by 64
Mitra, N. K., Banda, K., Altheide, T. K., Schaffer, L., Johnson‐Pais, T. L., Beuten, J., Leach, R. J., Angata, T., Varki, N. M., & Varki, A. P. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.244152 · Cited by 62
Wang, Z., Wang, S., Jia, Z., Hu, Y., Cao, D., Yang, M., Liu, L., Gao, L., Qiu, S., Yan, W., et al. (2022) · Cancer Letters · doi:10.1016/j.canlet.2023.216184 · Cited by 60
Jin, Y., Lee, J.-H., Kim, Y.-M., Oh, G. T., & Lee, H. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.03.014 · Cited by 59
Growth Differentiation Factor-15: a New Biomarker in Cardiovascular Disease
Kempf, T., & Wollert, K. C. (2009) · Herz · doi:10.1007/s00059-009-3317-3 · Cited by 56
Si, Y., Liu, X., Cheng, M., Wang, M., Gong, Q., Yang, Y., Wang, T., & Yang, W. Z. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019967 · Cited by 59
Sasahara, A., Tominaga, K., Nishimura, T., Yano, M., Kiyokawa, E., Noguchi, M., Noguchi, M., Kanauchi, H., Ogawa, T., Minato, H., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.15276 · Cited by 55
Li, H., Li, Q.-Y., Jin, M.-J., Lu, C.-F., Mu, Z.-Y., Xu, W., Song, J., Zhang, Y., & Zhang, S. (2021) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-021-03604-8 · Cited by 55
Karczewska‐Kupczewska, M., Kowalska, I., Nikołajuk, A., Adamska, A., Otziomek, E., Górska, M., & Strączkowski, M. (2011) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2011.04139.x · Cited by 56
Montoro‐García, S., Hernández‐Romero, D., Jover, E., García‐Honrubia, A., Vilchez, J. A., Casas, T., Martı́nez, P., Climent, V. E., Caballero, L., Valdés, M., et al. (2011) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2011.08.022 · Cited by 52
Yeung, S. L. A., Luo, S., & Schooling, C. M. (2019) · Diabetologia · doi:10.1007/s00125-019-4913-2 · Cited by 54
Cancer-Associated Muscle Wasting—Candidate Mechanisms and Molecular Pathways
Armstrong, V., Fitzgerald, L. W., & Bathe, O. F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239268 · Cited by 53
Macrophage Inhibitory Cytokine-1 Regulates Melanoma Vascular Development
Huh, S. J., Chung, C.-Y., Sharma, A. K., & Robertson, G. P. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090963 · Cited by 53
Nakajima, T., Shibasaki, I., Sawaguchi, T., Haruyama, A., Kaneda, H., Nakajima, T., Hasegawa, T., Arikawa, T., Obi, S., Sakuma, M., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8101576 · Cited by 53
The development of gene therapy for diseases of the lung
Gill, D. R., Davies, L. A., Pringle, I. A., & Hyde, S. C. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-3317-z · Cited by 50
Arafat, K., Iratni, R., Takahashi, T., Parekh, K. A., Dhaheri, Y. A., Adrian, T. E., & Attoub, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066931 · Cited by 49
Borner, T., Arnold, M., Ruud, J., Breit, S. N., Langhans, W., Lutz, T. A., Blomqvist, A. G., & Riediger, T. (2016) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12169 · Cited by 50
Self-citationCruickshank, T., MacDonald, T. M., Walker, S. P., Keenan, E., Dane, K. M., Middleton, A., Kyritsis, V. P., Myers, J., Cluver, C. A., Hastie, R. M., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.020302 · Cited by 48
Growth-differentiation factor-15 and functional outcome after acute ischemic stroke
Gröschel, K., Schnaudigel, S., Edelmann, F., Niehaus, C., Weber-Krüger, M., Haase, B., Lahno, R., Seegers, J., Wasser, K., Wohlfahrt, J., et al. (2012) · Journal of Neurology · doi:10.1007/s00415-011-6379-0 · Cited by 48
Weide, B., Schäfer, T., Martens, A., Kuzkina, A., Uder, L., Noor, S., Garbe, C., Harter, P. N., Mittelbronn, M. G. A., & Wischhusen, J. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.07.016 · Cited by 47
CRP Stimulates GDF15 Expression in Endothelial Cells through p53
Kim, Y., Hooten, N. N., & Evans, M. K. (2018) · Mediators of Inflammation · doi:10.1155/2018/8278039 · Cited by 47
Effect of bariatric surgery on plasma GDF15 in humans
Kleinert, M., Bojsen-Møller, K. N., Jørgensen, N. B., Svane, M. S., Martinussen, C., Kiens, B., Wojtaszewski, J. F. P., Madsbad, S., Richter, E. A., & Clemmensen, C. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00010.2019 · Cited by 48
Wang, X., Jiang, X., Yu, X., Wang, L., He, S., Feng, F., Guo, L., Jiang, W. B., & Lu, S. (2013) · Cancer Science · doi:10.1111/cas.12331 · Cited by 46
Vaňhara, P., Slabáková, E., Kozubı́k, A., Jurdic, P., Souček, K., & Šmarda, J. (2009) · Differentiation · doi:10.1016/j.diff.2009.07.008 · Cited by 45
Growth differentiation factor 15 (GDF-15) in endocrinology
Iglesias, P., Silvestre, R. A., & Díez, J. J. (2023) · Endocrine · doi:10.1007/s12020-023-03377-9 · Cited by 45
Functional role of peroxisome‐proliferator‐activated receptor γ in hepatocellular carcinoma
Wu, C., Farrell, G. C., & Yu, J. Q. (2012) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2012.07213.x · Cited by 43
Vočka, M., Langer, D., Frýba, V., Petrtýl, J., Hanuš, T., Kalousová, M., Zima, T., & Petruzelka, L. B. (2018) · Cancer Biomarkers · doi:10.3233/cbm-170792 · Cited by 43
Mitsopoulos, P., & Suntres, Z. E. (2011) · Journal of Toxicology · doi:10.1155/2011/808967 · Cited by 44
Metadata
- Authors
- Bauskin, A. R., Brown, D. A., Kuffner, T., Johnen, H., Luo, X. W., Hunter, M., & Breit, S. N.
- Affiliations
- UNSW Sydney (AU)
- Centre for Immunology, St. Vincent's Hospital and University of New South Wales, Sydney, Australia
- Venue
- Cancer Research
- Published
- 2006-05-15
- Volume
- 66
- Issue
- 10
- Pages
- 4983-4986
- ISSN
- 0008-5472 (ISSN-L)
- 1538-7445
- OpenAlex
- W2020474446
- Cited by
- 251
- References
- 27
- Citations by year
- 2025: 8 · 2024: 13 · 2023: 14 · 2022: 7 · 2021: 16 · 2020: 16 · 2019: 13 · 2018: 6 · 2017: 13 · 2016: 15 · 2015: 12 · 2014: 16 · 2013: 13 · 2012: 12
- FWCI
- 4.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cancer Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Life Sciences › Immunology and Microbiology › Immunology › Macrophage Migration Inhibitory Factor
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mechanisms of cancer metastasis
- Keywords
- MIC-1, TGF-beta superfamily, carcinogenesis, cancer diagnosis, tumor microenvironment, tumor progression, tumor invasion
- MeSH terms
- Animals, Cell Transformation, Neoplastic, Humans, Neoplasms, Biomarkers, Tumor, Cytokines, Growth Differentiation Factor 15
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
