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Single‐Cell RNA Sequencing Identifies MMP11 + Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

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Siglec‐G Suppresses CD8 + T Cells Responses through Metabolic Rewiring and Can be Targeted to Enhance Tumor Immunotherapy

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CAF-mediated tumor vascularization: From mechanistic insights to targeted therapies

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Cancer-associated fibroblasts: central players in cancer hallmarks and therapeutic resistance

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Metabolic reprogramming in KRAS-mutant cancers: Proven targetable vulnerabilities and potential therapeutic strategies

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CRCs-CAFs crosstalk-targeted nano-delivery system reprograms tumor microenvironment for oxaliplatin resistance reversing and liver metastasis inhibition in colorectal cancer

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Host and microbiome lipid metabolism in colorectal cancer development and therapy

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POSTN + CAF-Derived Migrasomes Drive Hepatocellular Carcinoma Progression and Confer Resistance to Immunotherapy

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Tumor-associated macrophages enhance peripheral nerve tumor infiltration and spinal cord repair

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SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRAS G12D inhibitor in KRAS LUAD

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Metformin induces apoptosis in TRAIL-resistant colorectal cancer cells

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Single-cell and spatial transcriptome profiling identifies the immunosuppressive spatial niche in KRAS -mutant colorectal cancer

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Characterization of metastasis-specific macrophages in colorectal cancer for prognosis prediction and immunometabolic remodeling

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Resistance to oncolytic virotherapy: Multidimensional mechanisms and therapeutic breakthroughs (Review)

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MC1R regulates T regulatory cell differentiation through metabolic reprogramming to promote colon cancer

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Single cell analysis reveals that SPP1+ macrophages enhance tumor progression by triggering fibroblast extracellular vesicles

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Targeting lipid metabolism to enhance cancer immunotherapy

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Role of metabolic reprogramming of cancer‑associated fibroblasts in tumor development and progression (Review)

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Cancer-associated fibroblasts: Recent advances and therapeutic implications

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TFCP2 as a therapeutic nexus: unveiling molecular signatures in cancer

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Integration of Untargeted Metabolomics, Network Pharmacology, Single-Cell RNA Sequencing, and Molecular Dynamics Simulation Reveals GOT1, CYP1A2, and CA2 as Potential Targets of Huang Qin Decoction Preventing Colorectal Cancer Liver Metastasis

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GSDMB interacts with IGF2BP1 to suppress colorectal cancer progression by modulating DUSP6-ERK pathway

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Single-cell and bulk RNA-sequencing reveal PRRX2-driven cancer-associated fibroblast-mediated perineural invasion for predicting the immunotherapy outcome in colorectal cancer

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The Spatiotemporal Heterogeneity of Tumor-Associated Stromal Cells: Reprogramming Plasticity to Unlock Precision Cancer Immunotherapy

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Consensus clustering and development of a risk signature based on trajectory differential genes of cancer-associated fibroblast subpopulations in colorectal cancer

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Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer

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Neoadjuvant chemotherapy combined with bevacizumab for resectable colorectal liver metastasis with risk factors for recurrence: a multicenter real-world study

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Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

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Integrated Single-Cell Analysis Reveals the Heterogeneity of Tumor-Associated Macrophages and Their Implications for Immunotherapy in Colorectal Cancer

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Antibody–Drug Conjugates Targeting Resistance-Associated Signaling Pathways: Recent Advances and Future Perspectives

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The Significance of the Heterogeneity of Cancer-Associated Fibroblasts in Tumor Microenvironments

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Decoding the Plasticity of Cancer‐Associated Fibroblasts: Mechanistic Insights and Precision Targeting Strategies in Gastric Cancer Progression and Therapeutic Resistance

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Pharmacological SOS1 inhibitor BI-3406 demonstrates in vivo anti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumorsPreprint

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Single-cell sequencing reveals dysregulated cell type perturbations and critical mediator communication remodelling in colorectal cancer

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KRAS mutations in colorectal cancer: impacts on tumor microenvironment and therapeutic implications

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Elucidation of novel diagnostic biomarkers and therapeutic targets in colorectal carcinoma: an integrative approach leveraging multi-omics, computational biology, and single-cell sequencing technologies

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CYP1B1 Knockout in a Bovine Hepatocyte-like Cell Line (BFH12) Unveils Its Role in Liver Homeostasis and Aflatoxin B1-Induced Hepatotoxicity

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A ligand-centered framework for γδ T cell activation in colorectal cancer revealed by single-cell and transformer-based perturbation

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The DAG/PKC/CREB1/TGF-β1 axis drives shear-wave elastography stiffness and malignant progression in triple-negative breast cancer via lipid metabolic reprogramming

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One Mutation to Rule Them All: Mutant KRAS Controls Tumor Intrinsic and Microenvironment Signaling

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Tumor-associated macrophages enhance tumor innervation and spinal cord repairPreprint

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ENTR1 affects the progression of colon cancer by regulating energy metabolism under the influence of glycolysis

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Expression of serum HMGB1, SAA, and TSGF in patients with colon cancer and the value of prognostic assessment

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FAP as a prognostic biomarker and radiomics-based predictor of angiogenesis-associated recurrence in Adamantinomatous craniopharyngioma

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Analysis and prediction of serological indicators associated with colorectal interval polyposis after resection

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Multi-omics integration reveals CYTL1 and H6PD as key regulators of tumor metabolism in mesothelioma

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Pan-Immune-Inflammation Value (PIV) and Prognostic Nutritional Index (PNI) are Associated with Distant Metastasis in Colorectal Cancer with KRAS Mutation but Not in Those with KRAS Wild-Type

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Presence of Adipophilin-Positive Cancer-Associated Fibroblasts Is an Independent Poor Prognostic Indicator and Is Correlated with Immature-Type Desmoplastic Reaction in Patients with Colorectal Cancer

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KLF7 as a biomarker for the pre-metastatic state promotes colorectal cancer liver metastasis via TGFβ autocrine signaling

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LINC01063 promotes colon cancer progression via the miR-134-5p/KRAS axis and serves as a prognostic biomarker

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Association between serum lipids and colorectal polyps: a retrospective cross-sectional study

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