CoChat
Sign Up
Cited by 140Obsessive-Compulsive Spectrum DisordersNeurological disorders and treatmentsElectroconvulsive Therapy Studies

Bilateral anterior cingulotomy for refractory obsessive-compulsive disorder: long-term follow-up results

Open access
Jung, Hyun Ho, Kim, Chan-Hyung, Chang, Jong Hee, Park, Yong Gou, Chung, Sang Sup, Chang, Jin Woo·2006·Stereotactic and Functional Neurosurgery
DOI 10.1159/000095031
Open this paper in CoChat — free account

Abstract

Objective To investigate the long-term efficacy and adverse cognitive effects of stereotactic bilateral anterior cingulotomy as a treatment for refractory obsessive-compulsive disorder (OCD) patients. Materials and methods Seventeen patients suffering from refractory OCD underwent stereotactic bilateral anterior cingulotomies and were followed for 24 months. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Clinical Global Impression and other neuropsychological tests were used to assess the efficacy and cognitive changes of cingulotomy. The tests were taken before and 12 and 24 months after surgery. Results The mean improvement rate of the Y-BOCS score achieved from the baseline was 48%. Eight patients out of 17 met the responder criteria. During the 24-month follow-up, there were no significant adverse effects observed after surgery. Conclusions Bilateral anterior cingulotomy was effective for the treatment of refractory OCD, and no other significant adverse cognitive effects on long-term follow-up were found.

Integrity signals

Registry

Crossref · 10.1159/000095031

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The beneficial impact on OCD in those who respond to cingulotomy persists for at least two years.

    “Importantly, the beneficial impact on OCD on those who respond has been shown to persist for at least two years (Jung et al., 2006)”

    From The cingulum bundle: Anatomy, function, and dysfunction (2018) · cites this paper as Jung et al., 2006

  • No long-term changes have been found in performance of other memory tasks, including the Hopkins Verbal Learning Test, after cingulotomy.

    “Similar studies have again found no long term changes in the performance of other memory tasks, including the Hopkins Verbal Learning Test (Kim et al., 2003; Jung et al., 2006).”

    From The cingulum bundle: Anatomy, function, and dysfunction (2018) · cites this paper as Jung et al., 2006

  • Other formal tests of memory, including recall of the Rey-Taylor complex, show preserved performance after anterior cingulotomy.

    “Other formal tests of memory, including recall of the Rey-Taylor complex, also show preserved performance (Corkin, 1980; Jung et al., 2006).”

    From The cingulum bundle: Anatomy, function, and dysfunction (2018) · cites this paper as Jung et al., 2006

Cites

Flagged first, then by citations

2 of the 27 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Jung, H. H., Kim, C.-H., Chang, J. H., Park, Y. G., Chung, S. S., & Chang, J. W.
Affiliations
Yonsei University (KR)
ORCID
Venue
Stereotactic and Functional Neurosurgery
Publisher
S. Karger AG
Published
2006
Volume
84
Issue
4
Pages
184-189
ISSN
  • 1011-6125 (ISSN-L)
  • 1423-0372
DOI
10.1159/000095031
OpenAlex
W2131702737
Cited by
140
References
27
Citations by year
2026: 4 · 2024: 5 · 2023: 4 · 2022: 5 · 2021: 12 · 2020: 7 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 5 · 2015: 10 · 2014: 12 · 2013: 14 · 2012: 7
FWCI
11.08
Type
journal article
Language
en
Open access
Licence
Locations
  • Stereotactic and Functional Neurosurgery (publishedVersion)
  • PubMed (publishedVersion)
  • YUHSpace (Yonsei University Medical Library) (submittedVersion, cc-by-nc-nd)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Health Sciences › Medicine › Neurology › Neurological disorders and treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
Keywords
refractory obsessive-compulsive disorder, stereotactic neurosurgery, long-term efficacy, cognitive side effects, Yale-Brown Obsessive Compulsive Scale, treatment response, neuropsychological outcomes
MeSH terms
Adult, Anxiety Disorders, Cognition, Depressive Disorder, Female, Follow-Up Studies, Gyrus Cinguli, Humans, Functional Laterality, Male, Memory, Middle Aged, Obsessive-Compulsive Disorder, Stereotaxic Techniques, Treatment Outcome, Neurosurgical Procedures

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review