Cited by 108Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Online Self-Help as an Add-On to Inpatient Psychotherapy: Efficacy of a New Blended Treatment Approach

Open access

Zwerenz, Rüdiger, Becker, Jan, Knickenberg, Rudolf J., Siepmann, Martin, Hagen, Karin, Beutel, Manfred E.·2017·Psychotherapy and Psychosomatics

DOI 10.1159/000481177

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Depression is one of the most frequent and costly mental disorders. While there is increasing evidence for the efficacy of online self-help to improve depression or prevent relapse, there is little evidence in blended care settings, especially combined with inpatient face-to-face psychotherapy. Therefore, we evaluated whether an evidence-based online self-help program improves the efficacy of inpatient psychotherapy. METHODS: A total of 229 depressed patients were randomly allocated either to an online self-help program (intervention group [IG]; Deprexis) or an active control group (CG; weekly online information on depression) in addition to inpatient psychodynamic psychotherapy. Both groups had access to their respective experimental intervention for 12 weeks, regardless of inpatient treatment duration. Reduction of depressive symptoms, as measured with the Beck Depression Inventory-II, was the primary outcome at the end of the intervention (T2). RESULTS: Depressive symptoms were statistically significantly lower in the IG compared to the active CG at T2 with a moderate between-group effect size of d = 0.44. The same applied to anxiety (d = 0.33), quality of life (d = 0.34), and self-esteem (d = 0.38) at discharge from inpatient treatment (T1). No statistically significant differences were found regarding dysfunctional attitudes (d = 0.14) and work ability (d = 0.08) at T1. CONCLUSIONS: This is the first evidence for blended treatment combining online self-help with inpatient psychotherapy. The study opens new and promising avenues for increasing the efficacy of inpatient psychotherapy. Future studies should determine how integration of online self-help into the therapeutic process can be developed further.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1159/000481177

Cites

48 of 48 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765
The size and burden of mental disorders and other disorders of the brain in Europe 2010
Wittchen, H. U., Jacobi, F., Rehm, J., Gustavsson, A., Svensson, M., Jönsson, B., Olesen, J., Allgulander, C., Alonso, J., Faravelli, C., et al. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.07.018 · Cited by 3,754
Meta-analysis of experiments with matched groups or repeated measures designs
Dunlap, W. P., Cortina, J. M., Vaslow, J. B., & Burke, M. J. (1996) · Psychological Methods · doi:10.1037/1082-989x.1.2.170 · Cited by 1,693 · cited 1×
“Cohen’s d for within-group comparisons was calculated following the method of Dunlap et al. [ 49 , p. 171], correcting for the correlation between the 2 measures in order to avoid overestimation of effects.”
Method
Psychometric properties of the Beck Depression Inventory-II: a comprehensive review
Wang, Y.-P., & Gorenstein, C. (2013) · Revista Brasileira de Psiquiatria · doi:10.1590/1516-4446-2012-1048 · Cited by 1,577
Computer-based psychological treatments for depression: A systematic review and meta-analysis
Richards, D., & Richardson, T. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.02.004 · Cited by 1,442
The global burden of mental, neurological and substance use disorders: An analysis from the Global Burden of Disease Study 2010.
Whiteford, H. A., Ferrari, A. J., Degenhardt, L., Feigin, V., & Vos, T. (2015) · PLOS ONE · doi:10.1371/journal.pone.0116820 · Cited by 1,175
Reliabilität und Validität des revidierten Beck-Depressionsinventars (BDI-II): Befunde aus deutschsprachigen Stichproben
Kühner, C., Bürger, C., Keller, F., & Hautzinger, M. (2007) · Der Nervenarzt · doi:10.1007/s00115-006-2098-7 · Cited by 935
Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms: A Meta-analysis of Individual Participant Data
Karyotaki, E., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., Mira, A., Mackinnon, A., Meyer, B., Botella, C., Littlewood, E., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0044 · Cited by 691
Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects
Vittengl, J. R., Clark, L. A., Dunn, T. W., & Jarrett, R. B. (2007) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.75.3.475 · Cited by 551 · cited 1×
“Even though inpatient psychotherapy has been shown to improve depressive symptoms considerably [27–29] , patients do not fully remit within 4–8 weeks, and they are at an increased risk for relapse or readmission [30, 31] .”
Background

Show all 48 references

Sorted by citations

Interventions to improve return to work in depressed people
Nieuwenhuijsen, K., Verbeek, J. H. A. M., Neumeyer‐Gromen, A., Verhoeven, A. C., Bültmann, U., & Faber, B. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006237.pub4 · Cited by 234
Chatbot-Delivered Psychotherapy for Adults With Depressive and Anxiety Symptoms: A Systematic Review and Meta-Regression
Lim, S. M., Shiau, C. W. C., Cheng, L. J., & Lau, Y. (2022) · Behavior Therapy · doi:10.1016/j.beth.2021.09.007 · Cited by 163
Personalization strategies in digital mental health interventions: a systematic review and conceptual framework for depressive symptoms
Hornstein, S., Zantvoort, K., Lueken, U., Funk, B., & Hilbert, K. (2023) · Frontiers in Digital Health · doi:10.3389/fdgth.2023.1170002 · Cited by 134
Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports
Juul, S., Gluud, C., Simonsen, S., Frandsen, F. W., Kirsch, I., & Jakobsen, J. C. (2021) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2020-111407 · Cited by 135
The Advantages and Disadvantages of Online and Blended Therapy: Survey Study Amongst Licensed Psychotherapists in Austria
Schuster, R., Pokorny, R., Berger, T., Topooco, N., & Laireiter, A.-R. (2018) · Journal of Medical Internet Research · doi:10.2196/11007 · Cited by 121
Cost and Effectiveness of Blended Versus Standard Cognitive Behavioral Therapy for Outpatients With Depression in Routine Specialized Mental Health Care: Pilot Randomized Controlled Trial
Kooistra, L. C., Wiersma, J. E., Ruwaard, J., Neijenhuijs, K., Lokkerbol, J., van Oppen, P., Smit, F., & Riper, H. (2019) · Journal of Medical Internet Research · doi:10.2196/14261 · Cited by 84
Internet- and mobile-based aftercare and relapse prevention in mental disorders: A systematic review and recommendations for future research
Hennemann, S., Farnsteiner, S., & Sander, L. (2018) · Internet Interventions · doi:10.1016/j.invent.2018.09.001 · Cited by 86
Blended care-cognitive behavioral therapy for depression and anxiety in real-world settings: Pragmatic retrospective study
Lungu, A., Jun, J. J., Azarmanesh, O., Leykin, Y., & Chen, C. E.-J. (2020) · Journal of Medical Internet Research · doi:10.2196/18723 · Cited by 75
Effectiveness of a tailored, integrative Internet intervention (deprexis) for depression: Updated meta-analysis
Twomey, C. D., O’Reilly, G., Bültmann, O., & Meyer, B. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228100 · Cited by 79
Attrition in Conversational Agent–Delivered Mental Health Interventions: Systematic Review and Meta-Analysis
Jabir, A. I., Lin, X., Martinengo, L., Sharp, G., Theng, Y. L., & Car, L. T. (2023) · Journal of Medical Internet Research · doi:10.2196/48168 · Cited by 75
Results of the Optimune trial: A randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors
Holtdirk, F., Mehnert, A., Weiss, M., Mayer, J., Meyer, B., Bröde, P., Claus, M., & Watzl, C. (2021) · PLOS ONE · doi:10.1371/journal.pone.0251276 · Cited by 62
Effects of an epilepsy‐specific Internet intervention (Emyna) on depression: Results of the ENCODE randomized controlled trial
Meyer, B., Weiss, M., Holtkamp, M., Arnold, S., Brückner, K., Schröder, J., Scheibe, F., & Nestoriuc, Y. (2019) · Epilepsia · doi:10.1111/epi.14673 · Cited by 53
Patient Experiences Using a Self-Monitoring App in Eating Disorder Treatment: Qualitative Study
Lindgreen, P., Lomborg, K. E., & Clausen, L. (2018) · JMIR mhealth and uhealth · doi:10.2196/10253 · Cited by 54
Online therapy: an added value for inpatient routine care? Perspectives from mental health care professionals
Sander, J., Bolinski, F., Diekmann, S., Gäebel, W., Günther, K., Hauth, I., Heinz, A., Kleiboer, A. M., Riper, H. M., Trost, N., et al. (2021) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-021-01251-1 · Cited by 54
Effects of a depression-focused internet intervention in slot machine gamblers: a randomized controlled trial
Bücker, L., Bierbrodt, J., Hand, I., Wittekind, C., & Moritz, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0198859 · Cited by 50
Therapeutic Alliance in Technology-Based Interventions for the Treatment of Depression: Systematic Review
Wehmann, E., Köhnen, M., Härter, M. C., & Liebherz, S. (2020) · Journal of Medical Internet Research · doi:10.2196/17195 · Cited by 51
Internetbasierte Selbstmanagementinterventionen
Klein, J. P., Knaevelsrud, C., Bohus, M., Ebert, D. D., Gerlinger, G., Günther, K., Jacobi, C., Löbner, M., Riedel-Heller, S. G., Sander, J., et al. (2018) · Der Nervenarzt · doi:10.1007/s00115-018-0591-4 · Cited by 44
Improving the Course of Depressive Symptoms After Inpatient Psychotherapy Using Adjunct Web-Based Self-Help: Follow-Up Results of a Randomized Controlled Trial
Zwerenz, R., Baumgarten, C., Becker, J., Tibubos, A. N., Siepmann, M., Knickenberg, R. J., & Beutel, M. E. (2019) · Journal of Medical Internet Research · doi:10.2196/13655 · Cited by 43
CBT-informed psychological interventions for adult patients with anxiety and depression symptoms: A narrative review of digital treatment options
Biagianti, B., Foti, G., Liberto, A. D., Bressi, C., & Brambilla, P. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.01.057 · Cited by 44
Patient Engagement with Conversational Agents in Health Applications 2016–2022: A Systematic Review and Meta-Analysis
Cevasco, K. E., Morrison Brown, R. E., Woldeselassie, R., & Kaplan, S. (2024) · Journal of Medical Systems · doi:10.1007/s10916-024-02059-x · Cited by 35
“The authors stated that the higher discharge HAQ scores suggest a desire of participants to interact with a chatbot in the same way they do with humans, and sup - ports the theory of media equation, which claims that people tend to treat computers or other media as if they were real people [58 ].”
Background
Assessment of Use and Preferences Regarding Internet-Based Health Care Delivery: Cross-Sectional Questionnaire Study
Paslakis, G., Fischer‐Jacobs, J., Pape, L., Schiffer, M., Gertges, R., Tegtbur, U., Zimmermann, T., Nöhre, M., & de Zwaan, M. (2019) · Journal of Medical Internet Research · doi:10.2196/12416 · Cited by 32
Die Mischung macht’s eben? Blended-Psychotherapie als Ansatz der Digitalisierung in der Psychotherapie
Bielinski, L. L., Trimpop, L., & Berger, T. (2021) · Psychotherapeut · doi:10.1007/s00278-021-00524-3 · Cited by 36
Effects, Adherence, and Therapists’ Perceptions of Web- and Mobile-Supported Group Therapy for Depression: Mixed-Methods Study
Schuster, R., Kalthoff, I., Walther, A., Köhldorfer, L., Partinger, E., Berger, T., & Laireiter, A.-R. (2019) · Journal of Medical Internet Research · doi:10.2196/11860 · Cited by 25
“In this regard, first studies in routine care found additive effects of traditional face-to-face therapy augmented with Web-based therapy elements [29,30].”
A blended rational emotive occupational health coaching for job-stress among teachers of children with special education needs
Okeke, F. C., Onyishi, C. N., Nwankwor, P. P., & Ekwueme, S. C. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100482 · Cited by 37
Patients’ Experiences of Web- and Mobile-Assisted Group Therapy for Depression and Implications of the Group Setting: Qualitative Follow-Up Study
Schuster, R., Sigl, S., Berger, T., & Laireiter, A.-R. (2018) · JMIR Mental Health · doi:10.2196/mental.9613 · Cited by 28
Challenges With the Use of Digital Sham: Systematic Review and Recommendations
Bos, E., Preller, K. H., Kaur, G., Malhotra, P., Kharawala, S., & Motti, D. (2023) · Journal of Medical Internet Research · doi:10.2196/44764 · Cited by 29
A systematic review and meta analysis on digital mental health interventions in inpatient settings
Diel, A., Schröter, I. C., Frewer, A.-L., Jansen, C., Robitzsch, A., Gradl-Dietsch, G., Teufel, M., & Bäuerle, A. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01252-z · Cited by 31
Brief App-Based Cognitive Behavioral Therapy for Anxiety Symptoms in Psychiatric Inpatients: Feasibility Randomized Controlled Trial
Sharma, G., Schlosser, L., Jones, B. D. M., Blumberger, D. M., Gratzer, D., Husain, M. O., Mulsant, B. H., Rappaport, L., Stergiopoulos, V., & Husain, M. I. (2022) · JMIR Formative Research · doi:10.2196/38460 · Cited by 25
Clinicians' perspective on an app for patient self‐monitoring in eating disorder treatment
Lindgreen, P., Clausen, L., & Lomborg, K. E. (2018) · International Journal of Eating Disorders · doi:10.1002/eat.22833 · Cited by 25
Die Mischung macht’s eben? Blended-Psychotherapie als Ansatz der Digitalisierung in der Psychotherapie
Bielinski, L. L., Trimpop, L. F., & Berger, T. (2021) · Open Access CRIS of the University of Bern · doi:10.48350/164137 · Cited by 22
Immediate and long-term effectiveness of adding an Internet intervention for depression to routine outpatient psychotherapy: Subgroup analysis of the EVIDENT trial
Schuster, R., Laireiter, A., Berger, T., Moritz, S., Meyer, B., Hohagen, F., & Klein, J. P. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.05.122 · Cited by 23
Feasibility, adherence, and effectiveness of blended psychotherapy for severe mental illnesses: scoping review
Ehrt-Schäfer, Y., Rusmir, M., Vetter, J., Seifritz, E., Müller, M., & Kleim, B. (2023) · JMIR Mental Health · doi:10.2196/43882 · Cited by 24
“%) reported significant effects in favor of the intervention [43,44,46,59], with 2 of them using the same study population [43,44].”
BackgroundMethodResultInfluential
Feasibility of a blended group treatment (bGT) for major depression: uncontrolled interventional study in a university setting
Schuster, R., Fichtenbauer, I., Sparr, V. M., Berger, T., & Laireiter, A.-R. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-018412 · Cited by 23
Effectiveness of blended cognitive behavioral therapy versus treatment as usual for depression in routine specialized mental healthcare: E-COMPARED trial in the Netherlands
Kemmeren, L. L., van Schaik, A., Draisma, S., Kleiboer, A., Riper, H., & Smit, J. H. (2023) · Cognitive Therapy and Research · doi:10.1007/s10608-023-10363-y · Cited by 22
Evidence on Technology-Based Psychological Interventions in Diagnosed Depression: Systematic Review
Köhnen, M., Dreier, M., Seeralan, T., Kriston, L., Härter, M., Baumeister, H., & Liebherz, S. (2021) · JMIR Mental Health · doi:10.2196/21700 · Cited by 23
Digital health applications in the area of mental health
Schreiter, S., Mascarell-Maricic, L., Rakitzis, O., Volkmann, C., Kaminski, J. A., & Daniels, M. A. (2023) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.m2023.0208 · Cited by 24
Artificial Intelligence–Based Psychotherapeutic Intervention on Psychological Outcomes: A Meta‐Analysis and Meta‐Regression
Lau, Y., Ang, W. H. D., Ang, W. W., Pang, P. C., Wong, S. H., & Chan, K. S. (2025) · Depression and Anxiety · doi:10.1155/da/8930012 · Cited by 31
E-mental health implementation in inpatient care: Exploring its potential and future challenges
Assche, E. V., Bonroy, B., Mertens, M., den Broeck, L. V., Desie, K., Bolinski, F., Amarti, K., Kleiboer, A. M., Riper, H. M., & Daele, T. V. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.1027864 · Cited by 22
Stress in teachers of children with neuro-developmental disorders: Effect of blended rational emotive behavioral therapy
Obiweluozo, P. E., Dike, I. C., Ogba, F. N., Elom, C. O., Orabueze, F. O., Okoye-Ugwu, S., Ani, C., Onu, A. O., Ukaogo, V. O., Obayi, L. N., et al. (2021) · Science Progress · doi:10.1177/00368504211050278 · Cited by 20
Using the Personalized Advantage Index for Individual Treatment Allocation to Blended Treatment or Treatment as Usual for Depression in Secondary Care
Friedl, N., Krieger, T., Chevreul, K., Hazo, J., Holtzmann, J., Hoogendoorn, M., Kleiboer, A. M., Mathiasen, K., Urech, A., Riper, H. M., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020490 · Cited by 20
How Effective is a Web-Based Mental Health Intervention (Deprexis) in the Treatment of Moderate and Major Depressive Disorders when started during Routine Psychiatric Inpatient Treatment as an Adjunct Therapy? A Pragmatic Parallel-Group Randomized Controlled Trial
Richter, L. E., Machleit-Ebner, A., Scherbaum, N., & Bonnet, U. (2022) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/a-1826-2888 · Cited by 19
Digital interventions in adult mental healthcare settings: recent evidence and future directions
Dülsen, P., Bendig, E., Küchler, A., Christensen, H. M., & Baumeister, H. (2020) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000614 · Cited by 20
Time-Dependent Changes in Depressive Symptoms Among Control Participants in Digital-Based Psychological Intervention Studies: Meta-analysis of Randomized Controlled Trials
Tong, A. C. Y., Ho, F. S., Chu, O. H., & Mak, W. W. S. (2023) · Journal of Medical Internet Research · doi:10.2196/39029 · Cited by 19
Blending internet-based and tele group treatment: acceptability, effects, and mechanisms of change of cognitive behavioral treatment for depression
Schuster, R., Fischer, E., Jansen, C., Napravnik, N., Rockinger, S., Steger, N., & Laireiter, A.-R. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100551 · Cited by 15
Effectiveness of an Internet-Based Self-Guided Program to Treat Depression in a Sample of Brazilian Users: Randomized Controlled Trial
Lopes, R. D. C. T., da Rocha, G. C., Svacina, M. A., Meyer, B., Šipka, D., & Berger, T. (2023) · JMIR Formative Research · doi:10.2196/46326 · Cited by 14
Blended care in in-patient acute psychiatric care. The example of a group training for social competences in adults—A pretest–posttest feasibility study
Bendig, E., Küchler, A.-M., Baumeister, H., & Becker, T. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18189433 · Cited by 13
“Only one RCT (N = 229) by Zwerenz and colleagues [18] investigated a blended therapy concept for people with depressive symptoms in a psychosomatic clinic and found small to medium effect sizes in comparison to an active control group (d = 0.”
Background
Protocol for the Optimune trial: a randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors
Holtdirk, F., Mehnert-Theuerkauf, A., Weiss, M., Meyer, B., & Watzl, C. (2020) · Trials · doi:10.1186/s13063-019-3987-y · Cited by 14
Internet Interventions for Mental Health: Current State of Research, Lessons Learned and Future Directions
Bielinski, L. L., & Berger, T. (2020) · Counseling Psychology and Psychotherapy · doi:10.17759/cpp.2020280305 · Cited by 17
Adherence to e-health interventions for substance use and the factors influencing it: Systematic Review, meta-analysis, and meta-regression
Shams, F., Tai, A. M. Y., Kim, J., Boyd, M., Meyer, M., Kazemi, A., & Krausz, R. M. (2023) · Digital Health · doi:10.1177/20552076231203876 · Cited by 18
Characteristics of alcohol recovery narratives: Systematic review and narrative synthesis
Subhani, M., Talat, U., Knight, H., Morling, J. R., Jones, K. A., Aithal, G. P., Ryder, S. D., Llewellyn‐Beardsley, J., & Rennick‐Egglestone, S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0268034 · Cited by 13
Psychodynamic Online Treatment Following Supportive Expressive Therapy (SET):Therapeutic Rationale, Interventions and Treatment Process
Beutel, M. E., Böhme, K., Banerjee, M., & Zwerenz, R. (2018) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2018.64.2.186 · Cited by 12
Internet-Interventionen: Ein Überblick
Berger, T., & Krieger, T. (2018) · PiD - Psychotherapie im Dialog · doi:10.1055/a-0592-0282 · Cited by 12
Resources, support, and integration as potential barriers and facilitators to the implementation of blended therapy in the routine care of inpatients: a qualitative study
Gupta, N., Leuba, S., Seifritz, E., Berger, T., & Kawohl, W. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1417784 · Cited by 11
Feasibility, effectiveness and safety of the self-management intervention deprexis in routine medical care: Results of an uncontrolled observational study
Klein, J. P., Barthel, B., Berger, T., & Moritz, S. (2020) · Internet Interventions · doi:10.1016/j.invent.2020.100341 · Cited by 10
Integrating Patients’ Expectations into the Management of Their Depression: Report of a Symposium at the European College of Neuropsychopharmacology Congress
Demyttenaere, K., Frank, E., Castle, D. J., & Cindik-Herbrüggen, E. (2019) · Advances in Therapy · doi:10.1007/s12325-019-01038-w · Cited by 9
Blended Psychotherapy: Treatment Concept and Case Report for the Integration of Internet- and Mobile-Based Interventions into Brief Psychotherapy of Depressive Disorders
Titzler, I., Egle, V., Berking, M., Gumbmann, C., & Ebert, D. D. (2019) · Verhaltenstherapie · doi:10.1159/000503408 · Cited by 9
Top-funded companies offering digital health interventions for the prevention and treatment of depression: a systematic market analysis
Castro, Ó., Salamanca-Sanabria, A., Alattas, A., Teepe, G. W., Leidenberger, K., Fleisch, E., Car, L. T., Müller‐Riemenschneider, F., & Kowatsch, T. (2024) · Archives of Public Health · doi:10.1186/s13690-024-01424-z · Cited by 11
Effectiveness and acceptance of technology-based psychological interventions for the acute treatment of unipolar depression: a systematic review and meta-analysis (Preprint)
Köhnen, M., Kriston, L., Härter, M. C., Baumeister, H., & Liebherz, S. (2020) · Journal of Medical Internet Research · doi:10.2196/24584 · Cited by 11
Blended Care: Stand der Forschung und Implementierungsmöglichkeiten
Fenski, F., Behr, S., Schaeuffele, C., Boettcher, J., & Knaevelsrud, C. (2023) · Der Nervenarzt · doi:10.1007/s00115-023-01579-0 · Cited by 7
Does an Internet-Based Emotion Regulation Intervention Provide Added Value for Acute Psychiatric Inpatient Care? Protocol for a Randomized Controlled Pilot Trial
Bielinski, L. L., Wälchli, G., Nissen, C., Berger, T., & Moggi, F. (2023) · JMIR Research Protocols · doi:10.2196/47656 · Cited by 6
Effectiveness of an internet-based self-guided program to treat depression in a sample of Brazilian users: a study protocol
Lopes, R. D. C. T., Meyer, B., Berger, T., & Svacina, M. A. (2020) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2019-0582 · Cited by 9
„iFightDepression“ im stationären Setting
Schwarz, J., Mauche, N., Oehler, C., Rummel-Kluge, C., Hegerl, U., & Strauss, M. (2021) · Der Nervenarzt · doi:10.1007/s00115-021-01214-w · Cited by 4
The long shadow of early-change patterns: a 3-year follow-up after the use of a web-based intervention for mild to moderate depressive symptoms
Edelbluth, S., Klein, J. P., Schwartz, B., Hehlmann, M. I., Arndt, A., Rubel, J. A., Danilo Moggia, N., Berger, T., Meyer, B., Moritz, S., et al. (2024) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2024.2368520 · Cited by 5
E-Mental Health Interventions in Inpatient Care: Scoping Review
Diel, A., Schröter, I. C., Robitzsch, A., Jansen, C., Teufel, M., & Bäuerle, A. (2025) · Journal of Medical Internet Research · doi:10.2196/65947 · Cited by 5
Effectiveness of Blended Internet-based Self-help and Face-to-face Intervention for Depression: A Pilot Study from India
Sudarshan, S., Mehrotra, S., & Thirthalli, J. (2024) · Indian Journal of Psychological Medicine · doi:10.1177/02537176241238289 · Cited by 5
Examining the potential of an internet-based emotion regulation intervention added to acute psychiatric inpatient care: results from a randomized controlled pilot trial
Wälchli, G., Berger, T., Nissen, C., Moggi, F., & Bielinski, L. L. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.116326 · Cited by 5
Das Beste aus zwei Welten: Eine systematische Übersicht zu Faktoren der Implementierung einer “Blended Therapy” (Gemischte Therapie) in der Psychotherapeutischen Routineversorgung
Dech, M., Klawohn, J., & Romanczuk-Seiferth, N. (2022) · Verhaltenstherapie · doi:10.1159/000524332 · Cited by 6
Effectiveness and therapeutic alliance between face-to-face and online psychological interventions. A longitudinal study
Rotger, J. M., Coromina, L., & Segarra, V. C. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1624438 · Cited by 6
E-Mental-Health aftercare for children and adolescents after partial or full inpatient psychiatric hospitalization: study protocol of the randomized controlled DigiPuR trial
Finkbeiner, M., Kühnhausen, J., Schmid, J., Conzelmann, A., Dürrwächter, U., Wahl, L.-M., Kelava, A., Gawrilow, C., & Renner, T. J. (2022) · Trials · doi:10.1186/s13063-022-06508-1 · Cited by 4
Adding an App-Based Intervention to the Cognitive Behavioral Analysis System of Psychotherapy in Routine Outpatient Psychotherapy Treatment: Proof-of-Concept Study
Netter, A.-L., Beintner, I., & Brakemeier, E. (2022) · JMIR Formative Research · doi:10.2196/35482 · Cited by 4
Care models for mental health in a population of patients affected by COVID-19
Maresca, G., Formica, C., Cola, M. C. D., Buono, V. L., Latella, D., Cimino, V., Carnazza, L., Giambò, F. M., Parasporo, N., Bramanti, A., et al. (2022) · Journal of International Medical Research · doi:10.1177/03000605221097478 · Cited by 4
Blended-ALMAMAR app for inpatient mental health care for refugees: study protocol for a multicenter implementation study within the I-REACH consortium (Internet based REfugee mentAl healtH Care)
Reinhardt, I., Schmidt, L., Reske, D., Zielasek, J., Braun, G., Böttche, M., Boettcher, J., Burchert, S., Glaesmer, H., Knaevelsrud, C., et al. (2023) · BMC Health Services Research · doi:10.1186/s12913-023-10403-z · Cited by 5
Application and Extension of the Alcohol Recovery Narratives Conceptual Framework
Subhani, M., Talat, U., Knight, H., Morling, J. R., Jones, K. A., Aithal, G. P., Ryder, S. D., & Rennick‐Egglestone, S. (2023) · Qualitative Health Research · doi:10.1177/10497323231197384 · Cited by 3
SLEEPexpert+: Blending Internet-Based Cognitive Behavioral Therapy for Insomnia with In-Person Psychotherapy—A Feasibility Study in Routine Care
Schmid, D. S., Duss, S. B., Hertenstein, E., Nissen, C., Schneider, C., Urech, A., Vorster, A. P. A., & Berger, T. (2023) · Clinical and Translational Neuroscience · doi:10.3390/ctn7030027 · Cited by 3
Einsatz und Wirksamkeit von Digitalen Gesundheitsanwendungen in der Patientenversorgung
Ballerstein, M., & Jacob, G. A. (2022) · PSYCH up2date · doi:10.1055/a-1684-6199 · Cited by 3
Subjectivity and Technologies of Self
Plesa, P. (2025) · Palgrave Studies in the Theory and History of Psychology · doi:10.1007/978-3-031-91546-8_2 · Cited by 2
Students’ Perspectives on Digital Psychotherapy—Possible Solutions for Digital Inpatient-Like Care Concepts: Qualitative Interview Study
Robitzsch, R., Lalgi, T. J., Diel, A., Menningmann, S. S. G., Gresser, L. A., Wollenberg, P. J., Teufel, M., Bäuerle, A., & Robitzsch, A. (2026) · JMIR Medical Education · doi:10.2196/82830 · Cited by 2
The present and future of blended care: current research and introduction to the B-FIT framework
Bielinski, L. L., Büscher, R., Hennemann, S., Henning, C., Kohl, S. H., Meyer, C., Reinhold, A. S., Steubl, L., Titzler, I., Vogel, L., et al. (2026) · npj Digital Medicine · doi:10.1038/s41746-026-02526-4 · Cited by 2
Selbstmanagement Interventionen in der Behandlung depressiver Störungen: reif für die klinische Praxis?
Klein, J. P., Berger, T., Hautzinger, M., Lutz, W., Rose, M., Späth, C., Schröder, J., Hohagen, F., & Moritz, S. (2019) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/a-0849-9838 · Cited by 2
Digitale Ansätze bei Depression und Angst
Landgrebe, M., & Zwanzger, P. (2023) · InFo Neurologie + Psychiatrie · doi:10.1007/s15005-022-3122-6 · Cited by 2
Affektive Störungen
Sextl-Plötz, T., Franke, M., Baumeister, H., & Ebert, D. D. (2023) · Springer eBooks · doi:10.1007/978-3-662-65816-1_3 · Cited by 2
Efficacy of deprexis, an internet-based depression treatment: A meta-analysis of ten randomized controlled trials
Meyer, B., Bültmann, O., & Jacob, G. A. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.11.782 · Cited by 2
Welches digitale Angebot für wen?
Beintner, I., Backes, B., & Voderholzer, U. (2020) · DNP - Der Neurologe und Psychiater · doi:10.1007/s15202-020-0606-4 · Cited by 2
Psicoterapia On line II. Revisión a partir de la experiencia y la investigación
Barraquer, F. V. I., Rotger, J. M., & Cabré, V. (2021) · Clínica e Investigación Relacional · doi:10.21110/19882939.2021.150204 · Cited by 2
Blended Psychotherapy – verzahnte Psychotherapie: Behandlungskonzept und Fallbericht zur Integration von Internet- und Mobil-basierten Interventionen in die Kurzzeittherapie von depressiven Störungen
Titzler, I., Egle, V., Berking, M., Gumbmann, C., & Ebert, D. D. (2019) · Verhaltenstherapie · doi:10.1159/000502390 · Cited by 2
Recorded mental health recovery narratives for people with mental health problems and informal carers: the NEON research programme including 3 RCTs
Slade, M., Rennick‐Egglestone, S., Ali, Y., Newby, C., Yeo, C., Roe, J., Hui, A., Charles, A., Hare-Duke, L., Paterson, L., et al. (2025) · Programme Grants for Applied Research · doi:10.3310/ppog2281 · Cited by 1
Blended Therapy From the Perspective of Mental Health Professionals in Routine Mental Health Care: Mixed Methods Analysis of Cross-Sectional Survey Data
Kneubühler, A. M., von Känel, E., Grgić, K., Munkovic, E., Berger, T., & Bielinski, L. L. (2026) · JMIR Mental Health · doi:10.2196/78079 · Cited by 1
Evaluation des webbasierten PaarBalance®-Partnerschaftsprograms bei beratungsbegleitendem Einsatz
Keller, A., Babl, A., Berger, T., & Schindler, L. (2021) · Verhaltenstherapie · doi:10.1159/000518692 · Cited by 1
Onlinetherapien
Berger, T. (2022) · Elsevier eBooks · doi:10.1016/b978-3-437-23031-8.00035-2 · Cited by 1
Erste Erfahrungen mit einer Selbstmanagement-App in der stationären Suchtbehandlung
Kistner, S., & Kramer, D. (2022) · SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice · doi:10.1024/0939-5911/a000789 · Cited by 1
Psychodynamische Ansätze in der Online-Therapie
Eichenberg, C. (2023) · PDP – Psychodynamische Psychotherapie · doi:10.21706/pdp-22-3-230 · Cited by 1
Rhön-Campus-Konzept: Sektorenübergreifende Gesundheitsversorgung im ländlichen Raum
Walter, D., Marte, J., Auner, H., Müller, L., & Griewing, B. (2020) · Springer eBooks · doi:10.1007/978-3-658-29015-3_13 · Cited by 1
Who seeks Internet-based interventions for depression in Brazil?
Lopes, R. D. C. T., Svacina, M. A., Penedo, J. M. G., Roussos, A., Meyer, B., & Berger, T. (2021) · Estudos de Psicologia (Campinas) · doi:10.1590/1982-0275202138e190166 · Cited by 2
Patients’ experiences of blended Group Therapy for Depression – Part 1: Fit and Implications for the Group SettingPreprint
Schuster, R. (2017) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/su6xt · Cited by 1
Lieber online KI statt real KO
Ueberall, M. A. (2019) · Schmerzmedizin · doi:10.1007/s00940-019-0989-5
Schnittstellen und Versorgungsstrukturen
Beutel, M. E., Kraft-Bauersachs, C., Kreß, S., Leinberger, B., Loew, T. H., Olbrich, D., Schonnebeck, M., & Zwerenz, R. (2020) · Elsevier eBooks · doi:10.1016/b978-3-437-22611-3.00011-0
Adding an app-based intervention to the Cognitive Behavioral Analysis System of Psychotherapy (CBASP): Concept and Feasibility in a Pilot Routine Clinical Trial (Preprint)Preprint
Netter, A.-L., Beintner, I., & Brakemeier, E. (2021) · doi:10.2196/preprints.35482
Literaturverzeichnis zu Voderholzer/Hohagen (Hrsg.): Therapie psychischer Erkrankungen, 14. Auflage
(2019) · Elsevier eBooks · doi:10.1016/b978-3-437-24911-2.16001-8
Feasibility of a blended group intervention (bGT) for major depression: Uncontrolled interventional study in a university settingPreprint
Schuster, R. (2017) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/avfub
Rehabilitation
Zwerenz, R., Ebert, D. D., & Baumeister, H. (2023) · Springer eBooks · doi:10.1007/978-3-662-65816-1_22

Authors: Zwerenz, R., Becker, J., Knickenberg, R. J., Siepmann, M., Hagen, K., & Beutel, M. E.
Affiliations: Johannes Gutenberg University Mainz (DE)
Rhön-Klinikum (DE)
ORCID: Zwerenz, Rüdiger
Becker, Jan
Knickenberg, Rudolf J.
Siepmann, Martin
Beutel, Manfred E.
Venue: Psychotherapy and Psychosomatics
Publisher: S. Karger AG
Published: 2017
Volume: 86
Issue: 6
Pages: 341-350
ISSN: 0033-3190 (ISSN-L)
1423-0348
DOI: 10.1159/000481177
OpenAlex: W2765390755
Cited by: 108
References: 48
Citations by year: 2026: 5 · 2025: 8 · 2024: 9 · 2023: 19 · 2022: 13 · 2021: 13 · 2020: 17 · 2019: 11 · 2018: 11 · 2017: 2
FWCI: 12.83
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.karger.com/Services/SiteLicenses (vor)
www.karger.com/Services/SiteLicenses (tdm)
Locations: Psychotherapy and Psychosomatics (publishedVersion)
PubMed (publishedVersion)
Qucosa (Saxon State and University Library Dresden) (submittedVersion, other-oa)
Funders: Rhön-Klinikum
Topics: Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: online self-help, blended care, inpatient psychotherapy, depression, Deprexis, psychodynamic psychotherapy, depressive symptoms, anxiety, quality of life, self-esteem, dysfunctional attitudes, work ability
MeSH terms: Adult, Depressive Disorder, Female, Humans, Inpatients, Male, Middle Aged, Psychiatric Status Rating Scales, Self Care, Therapy, Computer-Assisted, Treatment Outcome, Internet, Psychotherapy, Psychodynamic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Online Self-Help as an Add-On to Inpatient Psychotherapy: Efficacy of a New Blended Treatment Approach

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks