Cited by 849Heart Rate Variability and Autonomic ControlNon-Invasive Vital Sign MonitoringBlood Pressure and Hypertension Studies

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Spectral Analysis of Blood Pressure and Heart Rate Variability in Evaluating Cardiovascular Regulation: A Critical Appraisal

Parati, Gianfranco, Saul, J. Philip, Di Rienzo, Marco, Mancia, Giuseppe·1995·Hypertension

DOI 10.1161/01.hyp.25.6.1276

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Abstract

Abstract Blood pressure variability includes rhythmic and nonrhythmic fluctuations that, with the use of spectral analysis, appear as clear peaks or broadband power, respectively. This review offers a concise and critical description of the spectral methods most commonly used (fast Fourier transform versus autoregressive modeling, time-varying versus broadband spectral analysis) and an evaluation of their advantages and disadvantages. It also provides insight into the problems that still affect the physiological and clinical interpretations of data provided by spectral analysis of blood pressure and heart rate variability. In particular, the assessment of blood pressure and heart rate spectra aimed at providing indexes of autonomic cardiovascular modulation is discussed. Evidence is given that multivariate models—which allow evaluation of the interactions between changes in blood pressure, heart rate, and other biological signals (such as respiratory activity) in the time or frequency domains—offer a more comprehensive approach to the assessment of cardiovascular regulation than that represented by the separate analysis of fluctuations in blood pressure or heart rate only.

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Book Review: Time Series Analysis: Forecasting and Control
Geurts, M. D., Box, G. E. P., & Jenkins, G. M. (1977) · Journal of Marketing Research · doi:10.2307/3150485 · Cited by 19,410
Textbook of Medical Physiology
Guyton, A. C., & Hall, J. E. (1966) · Annals of Internal Medicine · doi:10.7326/0003-4819-64-6-1363_2 · Cited by 9,760
Power Spectrum Analysis of Heart Rate Fluctuation: A Quantitative Probe of Beat-to-Beat Cardiovascular Control
Akselrod, S., Gordon, D., Ubel, F. A., Shannon, D. C., Berger, A. C., & Cohen, R. J. (1981) · Science · doi:10.1126/science.6166045 · Cited by 5,079
Spectral Analysis and its Applications.
Freiberger, W. F., Jenkins, G. M., & Watts, D. G. (1969) · Journal of the American Statistical Association · doi:10.2307/2286100 · Cited by 4,990
Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.
Pagani, M., Lombardi, F., Guzzetti, S., Rimoldi, O., Furlan, R., Pizzinelli, P., Sandrone, G., Malfatto, G., Dell'Orto, S., & Piccaluga, E. (1986) · Circulation Research · doi:10.1161/01.res.59.2.178 · Cited by 4,130
Time-frequency distributions-a review
Cohen, L. W. (1989) · Proceedings of the IEEE · doi:10.1109/5.30749 · Cited by 3,593
Cardiovascular neural regulation explored in the frequency domain.
Malliani, A., Pagani, M., Lombardi, F., & Cerutti, S. (1991) · Circulation · doi:10.1161/01.cir.84.2.482 · Cited by 3,569
Spectrum analysis—A modern perspective
Kay, S., & Marple, S. L. (1981) · Proceedings of the IEEE · doi:10.1109/proc.1981.12184 · Cited by 3,151
Modern Spectral Estimation: Theory and Application
Kay, S. (1988) · Medical Entomology and Zoology · Cited by 2,495
Physiological aspects of primary hypertension.
Folkow, B. (1982) · Physiological Reviews · doi:10.1152/physrev.1982.62.2.347 · Cited by 1,768

Flagged first, then by citations

Show all 92 references

Research works printed but not linked: 20

10.1161/res.53.1.6861300 · DOI
Mancia G Zanchetti A. Blood pressure variability. In: Zanchetti A Tarazi R eds. Handbook of Hypertension. Amsterdam Netherlands: Elsevier Science Publishing Co Inc; 1986;7:125-152.
10.1161/circ.84.2.1860193 · DOI
10.1161/res.32.5.564 · DOI
Hales S. Statistical Essays: Containing Haemastaticks. London UK: Innys Manby and Woodward; 1733:2.
Mayer S. Studien zur physiologic des herzens und der blutgefasse, 5: Abhandlung: Uber spontane blutdruck-schwankungen. Sber Akad Wiss Wien. 1876;74:281-307.
10.1161/circ.81.2.2297860 · DOI
Goldberg AL, Rigney DR, West BJ. Chaos and fractals in human physiology. Sci Am. 1990;29:456.
Fouad FM, Tarazi RC, Ferrario CM, Fighaly S, Alicandri C. Assessment of parasympathetic control of heart rate by a non-invasive method. Am J Physiol. 1984;246:H838-H842.
Saul JP Kaplan DT Kitney RI. Non-linear interactions between respiration and heart rate: a phenomenon common to multiple physiologic states. In: Proc Comp in Cardiology. Los Alamitos Calif: IEEE Computer Society Press; 1988;15:299-302.
Kitney RI Rompelman O. Analysis of the interaction of the human blood pressure and thermal system. In: Perkins J ed. Biomedical Computing. London UK: Pitman Medical; 1977:49-54.
10.1161/circ.90.1.8026003 · DOI
Zwiener U. Physiological interpretation of autospectra, coherence and phase spectra of blood pressure, heart rate, and respiration waves in man. Automedica. 1978;2:161-169.
10.1161/res.29.5.437 · DOI
10.1161/res.52.6.6861284 · DOI
Di Rienzo M Bertinieri G Cavallazzi A Ferrari AU Pedotti A Mancia G. Evaluation of arterial baroreflex by analysis of the intra-arterial (BP) recording. In: Dal Palù C Pessina A eds. Proceedings of International Symposium on Ambulatory Monitoring (ISAM) Padova. Cleup. 1986:149-151.
Appel ML Saul JP Berger RD Cohen RJ. Closed-loop identification of blood pressure variability mechanisms. In: Di Rienzo M Mancia G Parati G Pedotti A Zanchetti A eds. Blood Pressure and Heart Rate Variability. Amsterdam Netherlands: IOS Press; 1992:68-74.
10.1161/circ.89.1.8281644 · DOI
Mancia G Parati G. Reactivity to physical and behavioural stress and blood pressure variability in hypertension. In: Julius S Basset DR eds. Handbook of Hypertension Volume 9: Behavioural Factors in Hypertension. Amsterdam Netherlands: Elsevier Science Publishing; 1987:104-122.
Wesseling KH, de Wit B, Settels JJ, Klawe WH. On the indirect registration of finger blood pressure after Penaz. Funkt Biol Med. 1982;1:245-250.

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Pagani, M., & Malliani, A. (2000) · Journal of Hypertension · doi:10.1097/00004872-200018120-00002 · Cited by 121
Reference values of indices of spontaneous baroreceptor reflex sensitivity
Tank, J., Baevski, R. M., Fender, A., Baevski, A. R., Graves, K. F., Ploewka, K., & Weck, M. (2000) · American Journal of Hypertension · doi:10.1016/s0895-7061(99)00172-7 · Cited by 122
Autonomic responses during inhalation of natural fragrance of “Cedrol” in humans
Dayawansa, S., Umeno, K., Takakura, H., Hori, E., Tabuchi, E., Nagashima, Y., Oosu, H., Yada, Y., Suzuki, T., Ono, T., et al. (2003) · Autonomic Neuroscience · doi:10.1016/j.autneu.2003.08.002 · Cited by 118
Specific acupuncture sensation correlates with EEGs and autonomic changes in human subjects
Sakai, S., Hori, E., Umeno, K., Kitabayashi, N., Ono, T., & Nishijo, H. (2007) · Autonomic Neuroscience · doi:10.1016/j.autneu.2007.01.001 · Cited by 119
The physiological determinants and risk correlations of elevated heart rate
Palatini, P. (1999) · American Journal of Hypertension · doi:10.1016/s0895-7061(98)00207-6 · Cited by 118
Motor activity and autonomic cardiac functioning in major depressive disorder
Volkers, A. C. W. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00066-6 · Cited by 116
Effects of head-down-tilt bed rest on cerebral hemodynamics during orthostatic stress
Zhang, R., Zuckerman, J. H., Pawelczyk, J. A., & Levine, B. D. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.6.2139 · Cited by 120
Effects of two yoga based relaxation techniques on heart rate variability (HRV).
Sarang, P. S., & Telles, S. (2006) · International Journal of Stress Management · doi:10.1037/1072-5245.13.4.460 · Cited by 118
Sympathovagal Balance: A Critical Appraisal
Malík, M. (1998) · Circulation · doi:10.1161/01.cir.98.23.2643 · Cited by 118
Time versus frequency domain techniques for assessing baroreflex sensitivity
Persson, P. B., Rienzo, M. D., Castiglioni, P., Cerutti, C., Pagani, M., Honzíková, N., AKSELROD, S., & Parati, G. (2001) · Journal of Hypertension · doi:10.1097/00004872-200110000-00001 · Cited by 116
Self-citation
Power spectral analysis of heart rate variability and autonomic nervous system activity measured directly in healthy dogs and dogs with tachycardia-induced heart failure
Piccirillo, G., Ogawa, M., Song, J., Chong, V. J., Joung, B., Han, S., Magrì, D., Chen, L. S., Lin, S., & Chen, P. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.01.006 · Cited by 114
Mechanism of blood pressure and R‐R variability: insights from ganglion blockade in humans
Zhang, R., Iwasaki, K., Zuckerman, J. H., Behbehani, K., Crandall, C. G., & Levine, B. D. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.013398 · Cited by 113
The sympathetic nervous system in hypertension
Diedrich, A., Jordan, J., Tank, J., Shannon, J. R., Robertson, R. M., Luft, F. C., Robertson, D., & Biaggioni, I. (2003) · Journal of Hypertension · doi:10.1097/00004872-200309000-00017 · Cited by 113
Effects of body weight-supported treadmill training on heart rate variability and blood pressure variability in individuals with spinal cord injury
Ditor, D. S., Kamath, M. V., MacDonald, M. J., Bugaresti, J., McCartney, N., & Hicks, A. L. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01004.2004 · Cited by 112
Baroreflex contribution to blood pressure and heart rate oscillations: time scales, time-variant characteristics and nonlinearities
Rienzo, M. D., Parati, G., Radaelli, A., & Castiglioni, P. (2009) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2008.0274 · Cited by 113
Self-citation
Overview of the anatomy, physiology, and pharmacology of the autonomic nervous system
Wehrwein, E. A., Orer, H. S., & Barman, S. M. (2016) · Comprehensive Physiology · doi:10.1002/j.2040-4603.2016.tb00714.x · Cited by 114
The Psychophysiology Primer: A Guide to Methods and a Broad Review with a Focus on Human–Computer Interaction
Cowley, B. U., Filetti, M., Lukander, K., Torniainen, J., Henelius, A., Ahonen, L., Barral, O., Kosunen, I., Valtonen, T., Huotilainen, M., et al. (2016) · Foundations and Trends® in Human–Computer Interaction · doi:10.1561/1100000065 · Cited by 134
Clinical value of ambulatory blood pressure monitoring
Mallion, J.-M., Baguet, J.-P., Siche, J. P., Tremel, F., & Gaudemaris, R. D. (1999) · Journal of Hypertension · doi:10.1097/00004872-199917050-00001 · Cited by 107
An optimal frequency range for assessing the pressure reactivity index in patients with traumatic brain injury
Howells, T., Johnson, U., McKelvey, T., & Enblad, P. (2014) · Journal of Clinical Monitoring and Computing · doi:10.1007/s10877-014-9573-7 · Cited by 107
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Holwerda, S. W., Luehrs, R. E., DuBose, L. E., Collins, M. T., Wooldridge, N. A., Stroud, A., Fadel, P. J., Abboud, F. M., & Pierce, G. L. (2019) · Hypertension · doi:10.1161/hypertensionaha.118.12462 · Cited by 107
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Lombardi, C., Pengo, M. F., & Parati, G. (2019) · Autonomic Neuroscience · doi:10.1016/j.autneu.2019.102563 · Cited by 106
Self-citation
Spontaneous fluctuations in cerebral blood flow: insights from extended-duration recordings in humans
Zhang, R., Zuckerman, J. H., & Levine, B. D. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.278.6.h1848 · Cited by 105
Cardiovascular autonomic dysfunction in uremia
Robinson, T. G., & Carr, S. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00659.x · Cited by 101
Influence of demographic, anthropometric and lifestyle characteristics on heart rate and its variability in the population
Fagard, R. H., Pardaens, K., & Staessen, J. A. (1999) · Journal of Hypertension · doi:10.1097/00004872-199917110-00013 · Cited by 101
Sympathetic Nervous System Function and Dysfunction in Chronic Hemodialysis Patients
Rubinger, D., Backenroth, R., & Sapoznikov, D. (2013) · Seminars in Dialysis · doi:10.1111/sdi.12093 · Cited by 101
Non-invasive beat-to-beat blood pressure monitoring: new developments
Parati, G., Ongaro, G., Bilo, G., Glavina, F., Castiglioni, P., Rienzo, M. D., & Mancia, G. (2003) · Blood Pressure Monitoring · doi:10.1097/00126097-200302000-00007 · Cited by 101
Self-citation
Frequency response characteristics of sympathetically mediated vasomotor waves in humans
Stauss, H. M., Anderson, E. A., Haynes, W. G., & Kregel, K. C. (1998) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1998.274.4.h1277 · Cited by 100
Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humans
Bharucha, A. E., Charkoudian, N., Andrews, C. N., Camilleri, M., Sletten, D., Zinsmeister, A. R., & Low, P. A. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00153.2008 · Cited by 98
Comparison of direct and indirect (oscillometric) measurements of arterial blood pressure in conscious dogs
Bodey, A., Michell, A. R., Bovée, K. C., Buranakurl, C., & Garg, T. (1996) · Research in Veterinary Science · doi:10.1016/s0034-5288(96)90104-6 · Cited by 95

Authors: Parati, G., Saul, J. P., Di Rienzo, M., & Mancia, G.
Affiliations: Harvard University (US)
From the Istituto Scientifico Ospedale S. Luca, Centro Auxologico Italiano, Milano (G.P., G.M.); Medicina Interna I, Ospedale S. Gerardo, Monza and Università di Milano (G.P., G.M.) (Italy); Children’s Hospital, Department of Cardiology, Harvard Medical School, Boston (J.P.S.); Massachussetts Institute of Technology, Health Sciences and Technology, Cambridge (J.P.S.), Mass; and LaRC, Centro di Bioingegneria, Fondazione Pro Juventute, Milano, Italy (M. Di R.).
ORCID: Parati, Gianfranco
Saul, J. Philip
Mancia, Giuseppe
Venue: Hypertension
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1995-06
Volume: 25
Issue: 6
Pages: 1276-1286
ISSN: 0194-911X (ISSN-L)
1524-4563
DOI: 10.1161/01.hyp.25.6.1276
OpenAlex: W2102043873
Cited by: 849
References: 92
Citations by year: 2026: 13 · 2025: 18 · 2024: 22 · 2023: 22 · 2022: 25 · 2021: 15 · 2020: 22 · 2019: 28 · 2018: 37 · 2017: 31 · 2016: 45 · 2015: 24 · 2014: 31 · 2013: 35 · 2012: 35
FWCI: 26.01
Type: journal article
Language: en
Open access: closed
Locations: Hypertension (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Keywords: blood pressure variability, heart rate variability, spectral analysis, cardiovascular regulation, autonomic regulation, fast Fourier transform, autoregressive models, time-frequency analysis, multivariate analysis, respiratory activity, cardiac autonomic function
MeSH terms: Autonomic Nervous System, Blood Pressure, Fourier Analysis, Heart Rate, Humans, Hypertension, Signal Processing, Computer-Assisted

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Spectral Analysis of Blood Pressure and Heart Rate Variability in Evaluating Cardiovascular Regulation: A Critical Appraisal

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