The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.
Endothelial/Pericyte Interactions
Abstract
Interactions between endothelial cells and mural cells (pericytes and vascular smooth muscle cells) in the blood vessel wall have recently come into focus as central processes in the regulation of vascular formation, stabilization, remodeling, and function. Failure of the interactions between the 2 cell types, as seen in numerous genetic mouse models, results in severe and often lethal cardiovascular defects. Abnormal interactions between the 2 cell types are also implicated in a number of human pathological conditions, including tumor angiogenesis, diabetic microangiopathy, ectopic tissue calcification, and stroke and dementia syndrome CADASIL. In the present review, we summarize current knowledge concerning the identity, characteristics, diversity, ontogeny, and plasticity of pericytes. We focus on the advancement in recent years of the understanding of intercellular communication between endothelial and mural cells with a focus on transforming growth factor β, angiopoietins, platelet-derived growth factor, spingosine-1-phosphate, and Notch ligands and their respective receptors. We finally highlight recent important data contributing to the understanding of the role of pericytes in tumor angiogenesis, diabetic retinopathy, and hereditary lymphedema.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“pericyte-derived angiopoietin acts on endothelial Tie2 receptor and maintains BBB function (26, 570, 648);”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [26]
Citations
Cites
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
Maisonpierre, P. C., Suri, C., Jones, P. F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T. H., Papadopoulos, N., et al. (1997) · Science · doi:10.1126/science.277.5322.55 · Cited by 3,570
Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S. H., Sato, T. N., & Yancopoulos, G. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81813-9 · Cited by 2,872
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226
Self-citationNotch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
Joutel, A., Corpechot, C., Ducros, A., Vahedi, K., Chabriat, H., Mouton, P., Alamowitch, S., Domenga, V., Cécillion, M., Maréchal, E., et al. (1996) · Nature · doi:10.1038/383707a0 · Cited by 2,068
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
Davis, S., Aldrich, T. H., Jones, P. F., Acheson, A., Compton, D. L., Jain, V., Ryan, T. E., Bruno, J., Radziejewski, C., Maisonpierre, P. C., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81812-7 · Cited by 1,989
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg‐Buchholz, K., Fujiwara, Y., Gendron‐Maguire, M., Gridley, T., Wolburg, H., Risau, W., & Qin, Y. (1995) · Nature · doi:10.1038/376070a0 · Cited by 1,821
Hellström, M., Kalén, M., Lindahl, P., Abramsson, A., & Betsholtz, C. (1999) · Development · doi:10.1242/dev.126.14.3047 · Cited by 1,734
Self-citationMcAllister, K. A., Grogg, K. M., Johnson, D. W., Gallione, C. J., Baldwin, M. A., Jackson, C. E., Helmbold, E. A., Markel, D. S., McKinnon, W. C., Murrel, J., et al. (1994) · Nature Genetics · doi:10.1038/ng1294-345 · Cited by 1,475
Bergers, G., Song, S., Meyer-Morse, N., Bergsland, E. K., & Hanahan, D. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17929 · Cited by 1,361
Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1
Thurston, G., Suri, C., Smith, K., McClain, J., Sato, T. T., Yancopoulos, G. D., & McDonald, D. M. (1999) · Science · doi:10.1126/science.286.5449.2511 · Cited by 1,350
Cited by
Sorted by citations
Items 501–600 of 1,000
Molecular Mechanisms of Resistance to Tumour Anti-Angiogenic Strategies
Grépin, R., & Pagès, G. (2010) · Journal of Oncology · doi:10.1155/2010/835680 · Cited by 76
The impact of Fli1 deficiency on the pathogenesis of systemic sclerosis
Asano, Y., Bujor, A. M., & Trojanowska, M. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2010.06.008 · Cited by 78
Schulz, G. B., Wieland, E., Wüstehube‐Lausch, J., Boulday, G., Moll, I., Tournier‐Lasserve, E., & Fischer, A. (2015) · Stroke · doi:10.1161/strokeaha.114.007512 · Cited by 74
Javerzat, S., Franco, M., Herbert, J. M. J., Platonova, N., Peille, A.-L., Pantesco, V., Vos, J. D., Assou, S., Bicknell, R., Bikfalvi, A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007856 · Cited by 80
Dang, D. T., Chun, S. Y., Burkitt, K., Abe, M., Chen, S., Havre, P. A., Mabjeesh, N. J., Heath, E. I., Vogelzang, N. J., Cruz-Correa, M. R., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-1589 · Cited by 75
Liu, Y., Zhang, H., Wang, S., Guo, Y., Fang, X., Zheng, B., Gao, W., Yu, H., Chen, Z., Roman, R. J., et al. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00726.2020 · Cited by 73
Single-cell dual-omics reveals the transcriptomic and epigenomic diversity of cardiac non-myocytes
Wang, L., Yang, Y., Ma, H., Xie, Y., Xu, J., Near, D., Wang, H., Garbutt, T. A., Li, Y., Liu, J., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab134 · Cited by 73
Miller, C. L., Anderson, D. R., Kundu, R. K., Raiesdana, A., Nürnberg, S., Caceres, R. D., Cheng, K. W., Leeper, N. J., Chen, C., Chang, I., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003652 · Cited by 71
Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation
Rivron, N. C., Raiss, C. C., Liu, J., Nandakumar, A., Sticht, C., Gretz, N., Truckenmüller, R. K., Rouwkema, J., & van Blitterswijk, C. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117627109 · Cited by 74
Tissue Engineering the Vascular Tree
Traoré, M. A., & George, S. C. (2017) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2017.0010 · Cited by 80
Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update
Lin, F.-L., Wang, P.-Y., Chuang, Y.-F., Wang, J.-H., Wong, V. H. Y., Bui, B. V., & Liu, G.-S. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.06.029 · Cited by 74
Alarcón-Martínez, L., Yilmaz-Ozcan, S., Yemişçi, M., Schallek, J. B., Kılıç, K., Villafranca‐Baughman, D., Can, A., Polo, A. D., & Dalkara, T. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0761-z · Cited by 75
Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis
Chiaverina, G., di Blasio, L., Monica, V., Accardo, M., Palmiero, M., Peracino, B., Vara-Messler, M., Puliafito, A., & Primo, L. (2019) · Cells · doi:10.3390/cells8091109 · Cited by 71
Oxidative Stress and Microvessel Barrier Dysfunction
He, P., Talukder, M. A. H., & Gao, F. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00472 · Cited by 79
ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway
Zeng, P., Yang, J. A., Liu, L., Yang, X., Yao, Z., Ma, C., Zhu, H., Su, J., Zhao, Q., Feng, K., et al. (2020) · Theranostics · doi:10.7150/thno.49771 · Cited by 76
Emerging Role of Pericytes and Their Secretome in the Heart
Su, H., Cantrell, A. C., Zeng, H., Zhu, S., & Chen, J. (2021) · Cells · doi:10.3390/cells10030548 · Cited by 77
Nox4 Is a Major Source of Superoxide Production in Human Brain Pericytes
Kuroda, J., Ago, T., Nishimura, A., Nakamura, K., Matsuo, R., Wakisaka, Y., Kamouchi, M., & Kitazono, T. (2014) · Journal of Vascular Research · doi:10.1159/000369930 · Cited by 73
Perrotta, M., Lembo, G., & Carnevale, D. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030347 · Cited by 79
Squires, K. E., Montañez‐Miranda, C., Pandya, R. R., Torres, M. P., & Hepler, J. R. (2018) · Pharmacological Reviews · doi:10.1124/pr.117.015354 · Cited by 72
Britzen‐Laurent, N., Weidinger, C., & Stürzl, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065517 · Cited by 77
Correa, D., Somoza, R. A., Lin, P. Y., Schiemann, W. P., & Caplan, A. I. (2015) · International Journal of Cancer · doi:10.1002/ijc.29709 · Cited by 72
Human Blood-Vessel-Derived Stem Cells for Tissue Repair and Regeneration
Chen, C.-W., Corselli, M., Péault, B., & Huard, J. (2012) · BioMed Research International · doi:10.1155/2012/597439 · Cited by 72
Novel insights into pericyte–myofibroblast transition and therapeutic targets in renal fibrosis
Chang, F., Chou, Y., Chen, Y., & Lin, S. (2012) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2012.09.008 · Cited by 72
Lasala, G. P., Silva, J. A., & Minguell, J. J. (2011) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2011.08.053 · Cited by 72
The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1‐phosphate receptor 1
Schmid, G., Guba, M. O., Ischenko, I., Papyan, A., Joka, M., Schrepfer, S., Bruns, C. J., Jauch, K., Heeschen, C., & Graeb, C. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21181 · Cited by 74
Ye, L., Guo, H., Wang, Y., Peng, Y., Zhang, Y., Li, S., Yang, M., & Wang, L. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/8833098 · Cited by 71
Xue, X., Wu, X., Fan, Y., Han, S., Zhang, H., Sun, Y., Yin, Y., Yin, M., Chen, B., Sun, Z., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50564-x · Cited by 78
Reeves, C., Dufraine, J., Young, J. A. T., & Kitajewski, J. (2009) · Oncogene · doi:10.1038/onc.2009.383 · Cited by 71
Bone regulatory factors NFATc1 and Osterix in human calcific aortic valves
Alexopoulos, A., Bravou, V., Peroukides, S., Kaklamanis, L., Varakis, J. N., Alexopoulos, D., & Papadaki, H. H. (2008) · International Journal of Cardiology · doi:10.1016/j.ijcard.2008.10.014 · Cited by 75
Candela, P., Saint‐Pol, J., Kuntz, M., Boucau, M., Lamartinière, Y., Gosselet, F., & Fénart, L. (2014) · Brain Research · doi:10.1016/j.brainres.2014.10.047 · Cited by 78
Regulation of Mesenchymal Stem Cell Activity by Endothelial Cells
Saleh, F., Whyte, M., Ashton, P. D., & Genever, P. G. (2010) · Stem Cells and Development · doi:10.1089/scd.2010.0168 · Cited by 71
Age-related changes in brain support cells: Implications for stroke severity
Sohrabji, F., Bake, S., & Lewis, D. K. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.06.013 · Cited by 74
Shi, X., HAN, W., Yamamoto, H., Tang, W., Lin, X., Xiu, R., Trune, D. R., & Nuttall, A. L. (2008) · Microcirculation · doi:10.1080/10739680802047445 · Cited by 71
The restorative role of annexin A1 at the blood–brain barrier
McArthur, S., Loiola, R. A., Maggioli, E., Errede, M., Virgintino, D., & Solito, E. (2016) · Fluids and Barriers of the CNS · doi:10.1186/s12987-016-0043-0 · Cited by 73
Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
Hu, X., García, M., Weng, L., Jung, X., Murakami, J. L., Kumar, B., Warden, C., Todorov, I., & Chen, C. (2016) · Nature Communications · doi:10.1038/ncomms13095 · Cited by 71
Kuriakose, M., Rao, K. V. R., Younger, D., & Chandra, N. (2018) · Scientific Reports · doi:10.1038/s41598-018-26813-7 · Cited by 73
Retinoic Acid: A Key Regulator of Lung Development
Fernandes-Silva, H., Araújo-Silva, H., Correia‐Pinto, J., & Moura, R. S. (2020) · Biomolecules · doi:10.3390/biom10010152 · Cited by 71
Molecular Regulation of Sprouting Angiogenesis
Duran, C. L., Howell, D. W., Dave, J. M., Smith, R. L., Torrie, M. E., Essner, J. J., & Bayless, K. J. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160048 · Cited by 80
Padel, T., Özen, I., Boix, J., Barbariga, M., Gaceb, A., Roth, M., & Paul, G. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.06.002 · Cited by 70
Ayres-Sander, C. E., Lauridsen, H. M., Maier, C. L., Sava, P., Pober, J. S., & Gonzalez, A. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060025 · Cited by 72
Endosialin-Expressing Pericytes Promote Metastatic Dissemination
Viski, C., König, C., Kijewska, M., Mogler, C., Isacke, C. M., & Augustin, H. G. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-0932 · Cited by 72
Angiogenic biomaterials to promote therapeutic regeneration and investigate disease progression
Ngo, M. T., & Harley, B. A. C. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120207 · Cited by 72
Hasumi, Y., Kłosowska‐Wardęga, A., Furuhashi, M., Östman, A., Heldin, C., & Hellberg, C. B. (2007) · International Journal of Cancer · doi:10.1002/ijc.22999 · Cited by 71
Lee, S., Zeiger, A. S., Maloney, J. M., Kotecki, M., Vliet, K. J. V., & Herman, I. M. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/19/194115 · Cited by 71
Doukas, J., Mahesh, S. P., Umeda, N., Kachi, S., Akiyama, H., Yokoi, K., Cao, J., Chen, Z., Dellamary, L. A., Tam, B. Y. Y., et al. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21426 · Cited by 70
Functions of lipid raft membrane microdomains at the blood–brain barrier
Dodelet-Devillers, A., Cayrol, R., van Horssen, J., Haqqani, A. S., de Vries, H. E., Engelhardt, B., Greenwood, J., & Prat, A. (2009) · Journal of Molecular Medicine · doi:10.1007/s00109-009-0488-6 · Cited by 71
Emerging therapeutic targets in metastatic progression: A focus on breast cancer
Li, Z., & Kang, Y. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.03.003 · Cited by 71
Pericyte Regulation of Vascular Remodeling Through the CXC Receptor 3
Bodnar, R. J., Rodgers, M. E., Chen, W. C. W., & Wells, A. H. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.302012 · Cited by 69
Wirz, W., Antoine, M., Tag, C. G., Gressner, A. M., Korff, T., Hellerbrand, C., & Kiefer, P. (2008) · Differentiation · doi:10.1111/j.1432-0436.2007.00260.x · Cited by 73
Critical Role of Tissue Kallikrein in Vessel Formation and Maturation
Stone, O. A., Richer, C., Emanueli, C., van Weel, V., Quax, P. H. A., Katare, R., Kränkel, N., Campagnolo, P., Barcelos, L. S., Siragusa, M., et al. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.182139 · Cited by 69
Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
Pedersen, T. Ø., Blois, A. L., Xue, Y., Xing, Z., Sun, Y., Finne‐Wistrand, A., Lorens, J. B., Fristad, I., Leknes, K. N., & Mustafa, K. (2014) · Stem Cell Research & Therapy · doi:10.1186/scrt412 · Cited by 69
Song, Y. H., Shon, S. H., Shan, M., Stroock, A. D., & Fischbach, C. (2016) · Integrative Biology · doi:10.1039/c5ib00277j · Cited by 69
Gong, L., Zhang, Y., Zhu, Y., Lee, U., Luo, A. C., Li, X., Wang, X., Chen, D., Pu, W. T., Lin, R., et al. (2025) · Cell stem cell · doi:10.1016/j.stem.2025.05.014 · Cited by 73
Microvascular endowment in the developing chicken embryo lung
Makanya, A. N., Hlushchuk, R., Baum, O., Velinov, N., Ochs, M., & Djonov, V. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00371.2006 · Cited by 67
Monteiro, B. S., Neto, N. M. A., & Carlo, R. J. D. (2010) · Ciência Rural · doi:10.1590/s0103-84782010000100040 · Cited by 68
Mancini, M., Terzic, A., Conley, B. A., Oxburgh, L. H., Nicola, T., & Vary, C. (2009) · Developmental Dynamics · doi:10.1002/dvdy.22066 · Cited by 69
Angiocrine endothelium: from physiology to cancer
Pasquier, J., Ghiabi, P., Chouchane, L., Razzouk, K., Rafii, S., & Rafii, A. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02244-9 · Cited by 68
The Role of Vascular Cells in Pancreatic Beta-Cell Function
Burganova, G., Bridges, C. A., Thorn, P., & Landsman, L. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.667170 · Cited by 70
Pulmonary vascular development goes awry in congenital lung abnormalities
Kool, H. M., Mous, D. S., Tibboel, D., de Klein, A., & Rottier, R. J. (2014) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.21085 · Cited by 69
Vascular development and hemodynamic force in the mouse yolk sac
Garcia, M. D., & Larina, I. V. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00308 · Cited by 68
Milesi, S., Boussadia, B., Plaud, C., Catteau, M., Rousset, M.-C., de Bock, F., Schaeffer, M., Lerner‐Natoli, M., Rigau, V., & Marchi, N. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.07.010 · Cited by 67
Cipriani, P., Marrelli, A., Benedetto, P. D., Liakouli, V., Carubbi, F., Ruscitti, P., Alvaro, S., Pantano, I., Campese, A. F., Grazioli, P., et al. (2013) · Angiogenesis · doi:10.1007/s10456-013-9338-9 · Cited by 67
Cerebral ischemia/repefusion injury: From bench space to bedside
Nagy, Z., & Nardai, S. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.06.011 · Cited by 64
The pericyte microenvironment during vascular development
Payne, L. B., Zhao, H., James, C. C., Darden, J. A., McGuire, D. R., Taylor, S., Smyth, J. W., & Chappell, J. C. (2019) · Microcirculation · doi:10.1111/micc.12554 · Cited by 69
Role of Notch in endothelial biology
Fernández-Chacón, M., García-Gónzalez, I., Mühleder, S., & Benedito, R. (2021) · Angiogenesis · doi:10.1007/s10456-021-09793-7 · Cited by 67
Matarese, G., Isola, G., Anastasi, G., Favaloro, A., Milardi, D., Vermiglio, G., Vita, G., Cordasco, G., & Cutroneo, G. (2012) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2012.1024 · Cited by 66
Bone marrow Derived Pluripotent Cells are Pericytes which Contribute to Vascularization
Cai, X., Lin, Y., Friedrich, C. C., Neville, C. M., Pomerantseva, I., Sundback, C. A., Sharma, P., Zhang, Z., Vacanti, J. P., Hauschka, P. V., et al. (2009) · Stem Cell Reviews and Reports · doi:10.1007/s12015-009-9097-6 · Cited by 66
Recent developments on immunotherapy for brain cancer
Wainwright, D. A., Nigam, P., Thaçi, B., Dey, M., & Lesniak, M. S. (2012) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.2012.679929 · Cited by 66
Cellular Kinetics of Perivascular MSC Precursors
Chen, W. C. W., Park, T. S., Murray, I. R., Zimmerlin, L., Lazzari, L., Huard, J., & Péault, B. (2013) · Stem Cells International · doi:10.1155/2013/983059 · Cited by 68
Wakisaka, M., & Nagao, T. (2017) · Glycobiology · doi:10.1093/glycob/cwx047 · Cited by 66
Engineering stem cell cardiac patch with microvascular features representative of native myocardium
Qian, Z., Sharma, D., Jia, W., Radke, D., Kamp, T. J., & Zhao, F. (2019) · Theranostics · doi:10.7150/thno.29552 · Cited by 64
Jung, S., Kim, Y. S., Lee, Y., & Kim, J. S. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13279 · Cited by 67
M2 microglia-derived exosomes promote vascular remodeling in diabetic retinopathy
Wang, X., Xu, C., Bian, C., Ge, P., Lei, J., Wang, J., Xiao, T., Fan, Y., Gu, Q., Li, H., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02330-w · Cited by 68
Chappell, J. C., & Bautch, V. L. (2010) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)90002-1 · Cited by 65
Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2
Ohradanova‐Repic, A., Gradin, K., Baráthová, M., Zaťovičová, M., Holotnakova, T., Kopáček, J., Parkkila, S., Poellinger, L., Pastoreková, S., & Pastorek, J. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604685 · Cited by 65
Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice
Zeng, Q., Wu, Z., Duan, H., Jiang, X., Tu, T., Lü, D., Luo, Y., Wang, P., Song, L., Feng, J., et al. (2014) · Protein & Cell · doi:10.1007/s13238-014-0047-y · Cited by 65
Microfabricated Porous Silk Scaffolds for Vascularizing Engineered Tissues
Wray, L. S., Tsioris, K., Gil, E. S., Omenetto, F. G., & Kaplan, D. L. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201202926 · Cited by 65
Carstens, M. H., Gómez, A., Cortés, R., Turner, E., Pérez, C., Ocon, M., & Correa, D. (2016) · Stem Cell Research · doi:10.1016/j.scr.2016.12.001 · Cited by 65
Audrito, V., Managò, A., Gaudino, F., Sorci, L., Messana, V. G., Raffaelli, N., & Deaglio, S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01720 · Cited by 67
Medina‐Flores, F., Hurtado‐Alvarado, G., de Oca, A. C.-M., López-Cervantes, S. P., Königsberg, M., Deli, M. A., & Gómez‐González, B. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.05.077 · Cited by 67
From Pathobiology to the Targeting of Pericytes for the Treatment of Diabetic Retinopathy
Arboleda‐Velásquez, J. F., Valdez, C. N., Marko, C. K., & D'Amore, P. A. (2015) · Current Diabetes Reports · doi:10.1007/s11892-014-0573-2 · Cited by 65
Hutton, D. L., Moore, E., Gimble, J. M., & Grayson, W. L. (2013) · Tissue Engineering Part A · doi:10.1089/ten.tea.2012.0752 · Cited by 67
Macchiarelli, G., Jiang, J.-Y., Nottola, S. A., & Sato, E. (2006) · Microscopy Research and Technique · doi:10.1002/jemt.20305 · Cited by 64
Tabit, C. E., Coplan, M. J., Chen, P., Jeevanandam, V., Uriel, N. Y., & Liao, J. K. (2017) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2017.06.001 · Cited by 64
Truskey, G. A. (2010) · International Journal of High Throughput Screening · doi:10.2147/ijhts.s13459 · Cited by 64
Chapter 16 Pericyte Isolation and Use in Endothelial/Pericyte Coculture Models
Bryan, B. A., & D'Amore, P. A. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(08)02016-8 · Cited by 64
Dimova, I. I., Hlushchuk, R., Makanya, A. N., Styp‐Rekowska, B., Ceauşu, R. A., Flückiger-Mangual, S., Lang, S., Semela, D., le Noble, F. A. C., Chatterjee, S., et al. (2013) · Angiogenesis · doi:10.1007/s10456-013-9366-5 · Cited by 64
Neovascularization and Angiogenic Factors in Advanced Human Carotid Artery Stenosis
Pelisek, J., Well, G., Reeps, C., Rudelius, M., Kuehnl, A., Culmes, M., Poppert, H., Zimmermann, A., Berger, H., & Eckstein, H. (2012) · Circulation Journal · doi:10.1253/circj.cj-11-0768 · Cited by 63
Warrington, J. P., Csiszár, A., Johnson, D. A., Herman, T. S., Ahmad, S., Lee, Y. W., & Sonntag, W. E. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01024.2010 · Cited by 67
McGuire, P. G., Rangasamy, S., Maestas, J., & Das, A. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.235408 · Cited by 63
Avolio, E., & Madeddu, P. R. (2016) · Vascular Pharmacology · doi:10.1016/j.vph.2016.05.009 · Cited by 59
Beyond barrier functions: Roles of pericytes in homeostasis and regulation of neuroinflammation
Bhattacharya, A., Kaushik, D. K., Lozinski, B. M., & Yong, V. W. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24715 · Cited by 63
The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes
Hariharan, A., Weir, N., Robertson, C., He, L., Betsholtz, C., & Longden, T. A. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.601324 · Cited by 64
Self-citationHayden, M. R., Yang, Y., Habibi, J., Bagree, S. V., & Sowers, J. R. (2010) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.3.5.13653 · Cited by 62
Zhang, S., Bu, X., Zhao, H., Yu, J., Wang, Y., Li, D., Zhu, C., Zhu, T., Ren, T., Liu, X., et al. (2013) · The Journal of Pathology · doi:10.1002/path.4311 · Cited by 62
Fibroblast—Extracellular Matrix Interactions in Tissue Fibrosis
Frangogiannis, N. G. (2016) · Current Pathobiology Reports · doi:10.1007/s40139-016-0099-1 · Cited by 62
Tattersall, I., Du, J., Cong, Z., Cho, B. S., Klein, A. M., Dieck, C. L., Chaudhri, R. A., Cuervo, H., Herts, J. H., & Kitajewski, J. (2016) · Angiogenesis · doi:10.1007/s10456-016-9501-1 · Cited by 62
Yang, R., Liu, W.-T., Miao, L., Yang, X., Fu, J., Dou, B., Cai, A., Zong, X., Tan, C., Chen, H., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.11696 · Cited by 62
Wang, K., Lin, R., & Melero‐Martin, J. M. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2939-0 · Cited by 64
Hoffmann, D., Dvořáková, T., Stroobant, V., Bouzin, C., Daumerie, A., Solvay, M., Klaessens, S., Letellier, M.-C., Renauld, J., van Baren, N., et al. (2019) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-19-0040 · Cited by 63
Metadata
- Authors
- Armulik, A., Abramsson, A., & Betsholtz, C.
- Affiliations
- Karolinska Institutet (SE)
- Corresponding author
- Betsholtz, Christer
- Venue
- Circulation Research
- Published
- 2005-09-16
- Volume
- 97
- Issue
- 6
- Pages
- 512-523
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2115390024
- Cited by
- 2,048
- References
- 134
- Citations by year
- 2026: 39 · 2025: 62 · 2024: 97 · 2023: 108 · 2022: 90 · 2021: 116 · 2020: 121 · 2019: 101 · 2018: 92 · 2017: 110 · 2016: 117 · 2015: 131 · 2014: 122 · 2013: 120 · 2012: 114
- FWCI
- 5.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
- Health Sciences › Medicine › Oncology › Lymphatic System and Diseases
- Keywords
- pericytes, endothelial cells, pericyte-endothelial interactions, vascular remodeling, intercellular communication, TGF-beta, angiopoietins, platelet-derived growth factor, sphingosine-1-phosphate, Notch signaling, tumor angiogenesis, diabetic retinopathy, hereditary lymphedema, CADASIL, vascular calcification, cardiovascular defects
- MeSH terms
- Becaplermin, Animals, Calcinosis, Cell Communication, Cell Differentiation, Humans, Lysophospholipids, Membrane Proteins, Muscle, Smooth, Vascular, Platelet-Derived Growth Factor, Sphingosine, Signal Transduction, Transforming Growth Factor beta, Pericytes, Proto-Oncogene Proteins c-sis, Receptor, Platelet-Derived Growth Factor beta, Angiopoietin-1, Endothelial Cells, Receptor, TIE-2, Receptors, Lysosphingolipid, Receptors, Notch
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review