Cited by 2,082Aortic Disease and Treatment ApproachesConnective tissue disorders researchAortic aneurysm repair treatments

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2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

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Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Gyang Ross, Elsie, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., Santos Volgman, Annabelle·2022·Circulation

DOI 10.1161/cir.0000000000001106PMC PMC9876736

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Abstract

AIM: The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes). METHODS: A comprehensive literature search was conducted from January 2021 to April 2021, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through June 2022 during the guideline writing process, were also considered by the writing committee, where appropriate. Structure: Recommendations from previously published AHA/ACC guidelines on thoracic aortic disease, peripheral artery disease, and bicuspid aortic valve disease have been updated with new evidence to guide clinicians. In addition, new recommendations addressing comprehensive care for patients with aortic disease have been developed. There is added emphasis on the role of shared decision making, especially in the management of patients with aortic disease both before and during pregnancy. The is also an increased emphasis on the importance of institutional interventional volume and multidisciplinary aortic team expertise in the care of patients with aortic disease.

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Long, B., Keim, S. M., Gottlieb, M. A., Schauer, S. G., & Schmitz, G. (2024) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2024.11.013 · Cited by 5
Three-dimensional assessment of ascending aortic stiffness, motion, and growth in ascending thoracic aortic aneurysm
Tjahjadi, N., Kim, T., Marway, P. S., Figueroa, C. A., Baker, T. J., Hazenberg, C. E. V. B., van Herwaarden, J. A., Patel, H. J., Figueroa, C. A., & Burris, N. S. (2024) · European Heart Journal - Imaging Methods and Practice · doi:10.1093/ehjimp/qyae133 · Cited by 5
Distribution and Maturity of Medial Collagen Fibers in Thoracoabdominal Post-Dissection Aortic Aneurysms: A Comparative Study of Marfan and Non-Marfan Patients
Doukas, P., Hruschka, B., Bassett, C., Buhl, E. M., Simon, F., Saraber, P. J. M. H., Jacobs, M. J. H. M., Uhl, C., Schurgers, L. J., & Gombert, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms26010014 · Cited by 5
“A unique subgroup affected by these aneurysms includes individuals with Marfan syndrome, a genetic condition predisposing them to connective tissue abnormalities [5].”
Trends and Updates in the Management and Outcomes of Acute Uncomplicated Type B Aortic Dissection
de Kort, J. F., Hasami, N. A., Been, M., Grassi, V., Lomazzi, C., Heijmen, R. H., Hazenberg, C. E. V. B., van Herwaarden, J. A., & Trimarchi, S. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.12.060 · Cited by 5
Editor's Choice – A European Delphi Consensus on the Management of Abdominal Aortic Aneurysms in Patients with Heritable Aortic Diseases
Gil-Sala, D., Backer, J. F. A. D., HERZEELE, I. V., Teixidó‐Turà, G., Wanhainen, A., Bellmunt-Montoya, S., Bashiardes, E., Gonçalves, F. B., Bellmunt-Montoya, S., Berard, X., et al. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.01.033 · Cited by 5
Increased risk for thoracic aneurysms in female and familial abdominal aortic aneurysm patients
Liu, H., de Bruin, J. L., IJpma, A. S., Castelijns, C. G. M., Heijsman, D., Hussain, B., Bouwens, E., Brüggenwirth, H. T., Roos‐Hesselink, J. W., Raa, S. T., et al. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.03.477 · Cited by 5
Outcomes of Frozen Elephant Trunk for Type A Acute Aortic Dissection: A Nationwide, Population Based Study
Chiu, P.-H., Cheng, Y., Chang, F., Chen, C.-Y., Chan, Y., Wu, V. C., Chu, P., & Chen, S. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.07.003 · Cited by 5
Aortic Stenosis: Diagnosis, Molecular Mechanisms and Therapeutic Strategies—A Comprehensive Review
Banceu, C. M., Cristutiu, D., Gurzu, S., Harpa, M. M., Banceu, D. M., & Suciu, H. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14144949 · Cited by 8
Clinical guidelines Thoracic and thoracoabdominal aortic aneurysms
Redaktsiia (2025) · Russian Journal of Cardiology and Cardiovascular Surgery · doi:10.17116/kardio202518041493 · Cited by 5
Long-term survival and operative outcomes of the Bentall procedure for aortic root aneurysm, aortic dissection, and endocarditis
Lau, C., Gregg, A. C., Ram, E., Mack, C. A., Krieger, K., Rahouma, M., Gambardella, I., Soletti, G. J., Gaudino, M. F. L., & Girardi, L. N. (2025) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2025.09.018 · Cited by 5
Deep learning-driven false-lumen volumes predict adverse remodeling better than diameter in patients with residual aortic dissection on CT
Fournel, J., Masi, M. D., Lu, C., Omnès, V., Muselier, B., Ghattas, B., Bouchot, O., Kafi, M., Lalande, A., Gaudry, M., et al. (2025) · European Radiology · doi:10.1007/s00330-025-12116-9 · Cited by 5
A Comprehensive Review of Acute Type A Aortic Dissection: Epidemiology, Classification, Management Strategies, Mortality Risk Assessment, and Ethical Considerations for Patients who Refuse Blood Transfusions
Beliaev, A. M. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm44307 · Cited by 5
Sex‐Based Differences in Long‐Term Outcomes of Patients With Ascending Aortic Dilation
Abusafia, M., Jadam, S., Kalahasti, V., Deng, L., Ospina, S., Sultana, S., Gaballa, A., Vargo, P., Lou, X., Roselli, E., et al. (2025) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.125.045827 · Cited by 3
Strategies for Complex Reoperative Aortic Arch Reconstruction in Patients With Congenital Heart Disease
Frankel, W. C., & Roselli, E. E. (2022) · Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery Annual · doi:10.1053/j.pcsu.2022.12.006 · Cited by 5
In Vivo Validation of Modulated Acoustic Radiation Force–Based Imaging in Murine Model of Abdominal Aortic Aneurysm Using VEGFR-2–Targeted Microbubbles
Huang, Y., Herbst, E. B., Xie, Y., Li, Y., Islam, Z. H., Kent, E. W., Wang, B., Klibanov, A. L., & Hossack, J. A. (2023) · Investigative Radiology · doi:10.1097/rli.0000000000001000 · Cited by 5
Clinical Usefulness of Echocardiographic Measurement of Proximal Aortic Diameter in Early Differentiation Between Type A Acute Aortic Dissection and ST‐Segment–Elevation Myocardial Infarction
Kirigaya, J., Iwahashi, N., Abe, T., Gohbara, M., Hanajima, Y., Horii, M., Okada, K., Matsuzawa, Y., Yasuda, S., Kosuge, M., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.029506 · Cited by 5
A highly penetrant ACTA2 mutation of thoracic aortic disease
Bobba, C. M., Azarrafiy, R., Spratt, J. R., Hendrickson, J. E., Martin, T. D., Arnaoutakis, G. J., Jeng, E. I.-H., & Beaver, T. M. (2023) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-023-02420-0 · Cited by 5
Computed Tomography Angiography for Aortic Diseases
Garg, I., Siembida, J. M., Hedgire, S., Priya, S., & Nagpal, P. (2024) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2024.01.001 · Cited by 5
Adoption and clinical outcomes of fenestrated endovascular aneurysm repair in a regional, multistate community hospital system
Ullery, B. W., Hanes, D. A., Kirker, E. B., & Spinelli, K. J. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.02.030 · Cited by 5
Surgeon volume and outcomes following thoracic endovascular aortic repair for blunt thoracic aortic injury
Mandigers, T. J., Yadavalli, S. D., Rastogi, V., Marcaccio, C. L., Wang, S. X., Zettervall, S. L., Starnes, B. W., Verhagen, H. J. M., van Herwaarden, J. A., Trimarchi, S., et al. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.02.032 · Cited by 5
Comparison of surgical and conservative treatment outcomes for type a aortic intramural hematoma
Yin, L., Wang, J., Qiu, Z., Chen, X., & Su, C. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-02533-0 · Cited by 5
Utility of motor-evoked potentials in contemporary open thoracoabdominal aortic repair
Aru, R. G., Stonko, D. P., Tan, L. T., Sorber, R. A., Hicks, C. W., & Black, J. H. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.04.022 · Cited by 5
Long-term outcomes after aortic root replacement for bicuspid aortic valve–associated aneurysm
Rajesh, K., Chung, M., Levine, D., Norton, E. L., Patel, P. M., Childress, P., Zhao, Y., Wang, P., Leshnower, B. G., Kurlansky, P. A., et al. (2024) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2024.03.003 · Cited by 5
The Year in Aortic Surgery: Selected Highlights From 2023
Fernando, R. J., Coleman, S. R., Alghanem, F., Sanders, J. A., Kothari, P., Vanneman, M. W., Ochieng, P. O., & Augoustides, J. G. (2024) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2024.05.002 · Cited by 5
Diagnostic accuracy of transthoracic echocardiography for acute type A aortic syndrome: A systematic review and meta-analysis
Yeh, H.-T., Lu, S.-W., Cheng, T., Lu, J., Hsiao, C.-H., & Yen, C. (2024) · Biomedical Journal · doi:10.1016/j.bj.2024.100747 · Cited by 5
Challenges in Diagnosis of Non-A Non-B Acute Aortic Dissection
Borghese, O., Pisani, A., & Mastracci, T. M. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.05.010 · Cited by 5
Management and outcomes of aortic dissection type B in late pregnancy: A retrospective case series
Wang, Z., Yu, X. B., Ding, S., Zhang, W., Liang, C., & Chen, H. (2024) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.17923 · Cited by 5
Investigating the association between gut microbiome and aortic aneurysm diseases: a bidirectional two-sample Mendelian randomization analysis
Sun, Y., Dong, H., Sun, C., Du, D., Gao, R., Voevoda, M. I., Knyazev, R., & Wu, N. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1406845 · Cited by 6
Technical Aspects of Exclusive Transfemoral Route for Total Endovascular Arch Repair: A Custom-Made Device With Only Upward-Facing Inner Branches for Aortic Arch Treatment
Ferreira, M. M. D. V., Mannarino, M., Cunha, R., Ferreira, D., Capotorto, L. F., & Mannarino, G. (2024) · Journal of Endovascular Therapy · doi:10.1177/15266028241267734 · Cited by 5
Comprehensive sex-specific and age-dependent analysis of four-dimensional flow cardiovascular magnetic resonance assessed aortic blood flow-related parameters in normal subjects using single-vendor magnetic resonance systems and single-vendor software
Ramaekers, M. J. F. G., Kiefte, B. J. C. T., Adriaans, B. P., Juffermans, J. F., van Assen, H. C., Winkens, B., Wildberger, J. E., Lamb, H. J., Schalla, S. M., & Westenberg, J. J. M. (2024) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2024.101083 · Cited by 5
Age-Disturbed Vascular Extracellular Matrix Links to Abdominal Aortic Aneurysms
Yu, Z., Wu, A., Hao, K., Liu, J., Zhao, Y., Zhu, Y., Wang, X., Xiang, Y., Xin, H.-B., & Tian, X. (2024) · The Journals of Gerontology Series A · doi:10.1093/gerona/glae201 · Cited by 5
Sex Differences in Outcomes After Elective and Acute Aortic Surgery—A Single-Centre Experience over the Last Two Decades
Strypet, M., Bozic, C., Mansvelder, F. J., Breel, J. S., Jansen, E. K., de Klerk, E. S., González, D. E. L., Hermanns, H., & Eberl, S. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13216313 · Cited by 5
Computed tomography-based anatomical suitability of an Endo-Bentall prosthesis for ascending aortic aneurysms
Aldağ, M., Nana, P., Panuccio, G., Torrealba, J. I., Schofer, N., Spanos, K. T., Kodolitsch, Y. V., Brickwedel, J., Demal, T. J., Detter, C., et al. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.10.084 · Cited by 5
Patient Selection for Surgery vs Surveillance in Moderately Dilated Ascending Aorta: Insights From Treatment in Thoracic Aortic Aneurysm: Surgery versus Surveillance (TITAN:SvS), an International Prospective Trial
Makarem, A., Appoo, J. J., Boodhwani, M., Guo, M. H., Brownlee, S. A., Demers, P., Patel, H. J., Hughes, G. C., Dagenais, F., Chu, M. W. A., et al. (2025) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2025.01.020 · Cited by 5
Current Status of Treatment for the Acute Type A Aortic Dissection in Japan
Okita, Y. (2025) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/j.semtcvs.2025.02.008 · Cited by 5
Transport across the thoracic aortic wall: implications for aneurysm pathobiology, diagnosis, and treatment
Kailash, K. A., Akanda, S. R., Davis, A. L., Crandall, C. L., Zaghloul, M. S., Setton, L. A., Halabi, C. M., Zayed, M. A., & Wagenseil, J. E. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00886.2024 · Cited by 5
A novel open-vascular single-branched stent graft in total arch repair of type a aortic dissection one-year results of a prospective multicenter randomized controlled study
Gu, J., Zhang, W., Kang, L., Sun, Y., Li, J., Wang, Y., Ji, Q., Lu, S., Zhai, J., Huang, B., et al. (2025) · International Journal of Cardiology · doi:10.1016/j.ijcard.2025.133268 · Cited by 5
Radiomics and machine learning for predicting valve vegetation in infective endocarditis: a comparative analysis of mitral and aortic valves using TEE imaging
Esmaely, F., Moradnejad, P., Boudagh, S., & Bitarafan‐Rajabi, A. (2025) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2025.2500887 · Cited by 5
Redefining TAVR Valve Sizing
Yao, J., Wu, D., Yan, Y., Wang, M., Liu, X., Yuan, F., Xi, Z., Zhang, Q., Jiang, Z., Luo, T., et al. (2025) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2025.05.043 · Cited by 5
Inverse Agonist Activity of Angiotensin II Receptor Blocker Is Crucial for Prevention of Progressive Aortic Dilatation in Marfan Syndrome
Yagi, H., Akazawa, H., Liu, Q., Ito, S. M., Umei, M., Kadowaki, H., Matsuoka, R., Shindo, A., Okamura, S., Ueda, T., et al. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.322646 · Cited by 5
Natural History of Truncal Root Dilatation and Truncal Valve Regurgitation in Truncus Arteriosus
Sengupta, A., Gauvreau, K., Shukla, A., Kohlsaat, K., Colan, S. D., del Nido, P. J., Mayer, J. E., & Nathan, M. (2023) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2023.03.030 · Cited by 5
Clinical presentation, outcomes, and threshold for repair by sex in degenerative saccular vs fusiform aneurysms in the descending thoracic aorta
Rastogi, V., Guetter, C. R., Patel, P. B., Anjorin, A. C., Marcaccio, C. L., Yadavalli, S. D., Scali, S. T., Beck, A. W., Verhagen, H. J. M., & Schermerhorn, M. L. (2023) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2023.06.104 · Cited by 5
Safety of cerebrospinal ﬂuid drainage in descending and thoracoabdominal aortic replacement surgery
Nasir, A., Zafar, M. A., Abdelbaky, M., Papanikolaou, D., Ellauzi, H., Shaikh, M., Ziganshin, B. A., & Elefteriades, J. A. (2023) · Annals of Cardiothoracic Surgery · doi:10.21037/acs-2023-scp-0121 · Cited by 5
Comparative Study of Male and Female Patients Undergoing Frozen Elephant Trunk Total Arch Replacement
Benk, J., Berger, T., Kondov, S., D’Inka, M., Bork, M., Walter, T., Discher, P., Rylski, B., Czerny, M., & Kreibich, M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12196327 · Cited by 5
“Hence, close and continuous follow-up of these patients following the FET procedure has been recommended [1,2].”
BackgroundInfluential
Cerebrolysin in Patients with Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis
Kojder, K., Jarosz, K., Bosiacki, M., Andrzejewska, A., Zacha, S., Sołek-Pastuszka, J., & Jurczak, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12206638 · Cited by 5
Clinical application of four-dimensional flow cardiovascular magnetic resonance in Marfan syndrome: A systematic review and meta-analysis
Ma, Z., Zhou, Y., Li, P., He, W., & Li, M. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.102177 · Cited by 5
Transcatheter aortic valve replacement in patients with preoperative ascending aortic diameter ≥45 mm
An, K., Zhang, F., Ouyang, W., & Pan, X. (2023) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-23-324 · Cited by 5
Non-A Non-B Acute Aortic Dissection: Is There Some Confusion in the Radiologist’s Mind?
Valente, T., Sica, G., Romano, F., Rea, G., Lieto, R., FEO, M. D., Corte, A. D., Guarino, S., Massimo, C., Scaglione, M., et al. (2023) · Tomography · doi:10.3390/tomography9060174 · Cited by 5
“This statement is also reported in the 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease [24].”
Method
Surgical management and outcomes of coronary artery involvement secondary to acute type A aortic dissection: a retrospective cohort study
Wang, H., Jia, B., Zhong, Y., Chen, S., Luo, C., Qiao, Z., Ge, Y., Li, C., Liu, Y., & Zhu, J. (2023) · Journal of Thoracic Disease · doi:10.21037/jtd-23-990 · Cited by 5
“Prompt surgical repair constitutes the primary life-saving approach for patients with ATAAD (6).”
Influential
Cerebral and Aortic Aneurysms in Electroconvulsive Therapy Patients
Ullrich, H., Sartorius, A., & Karl, S. (2024) · Journal of Ect · doi:10.1097/yct.0000000000000997 · Cited by 5
Dietary vitamin C and vitamin E with the risk of aortic aneurysm and dissection: A prospective population-based cohort study
Zeng, C.-R., Gao, J., Wu, M., You, S., Chen, Z.-T., Gao, Q., Cai, Z., Liu, P., Cai, Y.-W., Liang, X., et al. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.01.024 · Cited by 5
Non-coronary arterial outcomes in people with type 1 diabetes mellitus: a Swedish retrospective cohort study
Avdic, T., Eliasson, B., Rawshani, A., Borén, J., Gerstein, H. C., Nordanstig, J., Rihawi, M., Beckman, J. A., McGuire, D. K., Ömerovic, E., et al. (2024) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2024.100852 · Cited by 6
One-year results of the Flowdynamics Dense Mesh Stent for residual dissection after proximal repair of stanford type A or type B aortic dissection: a multicenter, prospective, and randomized study
Chen, L., Duan, W., Li, Z., Wang, C., Yang, P., Liu, Y., Zuo, J., & Hu, J. (2024) · International Journal of Surgery · doi:10.1097/js9.0000000000001440 · Cited by 5
Complementary Thoracic Endovascular Aortic Repair (TEVAR) after Frozen Elephant Trunk for Residual Type A Aortic Dissection: Perioperative and Mid-Term Outcomes
Mylonas, S., Mammadov, R., & Dorweiler, B. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13103007 · Cited by 5
“Currently, a tear-oriented strategy with exclusion or resection of the primary entry tear in the ascending aorta and arch with an open distal anastomosis is recommended to improve survival and increase false-lumen thrombosis [1–3].”
Background
Genetic Analysis Reveals Key Regulatory Axis in Aortic Dissection: CBL Regulated by HOXB13 and microRNA-1321
Chen, Z., Gao, Q., Qiu, J., Ge, M., Wang, S., Liu, C., Wu, M., He, W., Wang, J., Chen, Y., et al. (2024) · Cardiovascular Innovations and Applications · doi:10.15212/cvia.2024.0034 · Cited by 5
Early three-dimensional growth in uncomplicated type B aortic dissection is associated with long-term outcomes
Marway, P. S., Figueroa, C. A., Tjahjadi, N., Baker, T. J., Mistelbauer, G., Bäumler, K., Hinostroza, V., Higashigaito, K., Mastrodicasa, D., Masotti, M., et al. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.08.059 · Cited by 5
Diagnosis of bicuspid aortic valves: CT vs. TTE
Sylivris, A., Liu, Z. F., Theuerle, J. D., & Lim, R. (2024) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-024-03290-w · Cited by 5
New Trends of Personalized Medicine in the Management of Abdominal Aortic Aneurysm: A Review
Alsabbagh, Y., Erben, Y., Vandenberg, J., & Farres, H. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14121148 · Cited by 6
“The Society for Vascular Surgery recommends surgical repair for AAAs ≥ 5.5 cm in men or ≥ 5.0 cm in women or for aneurysms exhibiting rapid growth—defined as an increase of 0.5 cm in 6 months or 1 cm in 1 year [18,19].”
Influential
Dimethyl fumarate is repurposed to ameliorate aortic aneurysm and dissection in mice
Wang, X., Kuang, J., Hu, X., Hu, X., Liu, Y.-H., Hu, C.-P., Wang, Q., Wang, Q., & Zhang, Z. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177215 · Cited by 9
Outcomes of type A aortic dissection in Australia
Knox, A., Gimpel, D., Lance, D. G., Rice, G. D., Crouch, G., Newland, R. F., Baker, R. A., & Bennetts, J. S. (2025) · ANZ Journal of Surgery · doi:10.1111/ans.19399 · Cited by 5
Remnant cholesterol and risk of aortic aneurysm and dissection: a prospective cohort Study from the UK biobank study and mendelian randomization analysis
Zhou, T., Lin, W., Yang, B., Liu, Y., Huang, W., Xie, N., Yang, F., Lin, Z., Hu, Z., Luo, S., et al. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02466-0 · Cited by 5
Assessment of the thoracic aorta after aortic root replacement and/or ascending aortic surgery using 3D relaxation-enhanced angiography without contrast and triggering
Gietzen, C., Janßen, J. P., Tristram, J., Cagman, B., Kaya, K., Terzis, R., Gertz, R. J., Gietzen, T., Pennig, H., Bunck, A. C., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1532661 · Cited by 6
Highlights and Perioperative Implications from the 2024 European Society of Cardiology Guidelines for the Management of Peripheral Arterial and Aortic Diseases
Kothari, P., Bodmer, N. J., Vanneman, M. W., Nguyen, Q.-S., & Kiwakyou, L. M. (2025) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2025.03.022 · Cited by 6
Impact of Aspirin Therapy on Progression of Thoracic and Abdominal Aortic Aneurysms
Mohammadmoradi, S., Heier, K., Driehaus, E. R., Alfar, H. R., Tyagi, S. C., McQuerry, K., & Whiteheart, S. W. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119224 · Cited by 5
Editor's Choice – Association between Pre-operative Disease Activity and Long Term Revascularisation Outcomes in Patients with Takayasu’s Arteritis: A Multicentre Retrospective Cohort Study
Li, X., Fang, C., Gao, S., Wu, Z., Du, L., Tian, X., Li, J., Chen, Z., Diao, Y., Li, Y., et al. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.04.068 · Cited by 5
The matrix reloaded – Addressing structural integrity of the aortic wall in aneurysmal disease
Wagenseil, J. E. (2023) · Biomaterials and Biosystems · doi:10.1016/j.bbiosy.2023.100072 · Cited by 5
Aortic arch endovascular branch and fenestrated repair: Initial Canadian experience with novel technology
Rockley, M. C., Rommens, K. L., McClure, R. S., Herget, E. J., Smith, H. N., & Moore, R. D. (2023) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2023.101274 · Cited by 5
Editor's Choice – Sex Related Anatomical Differences in Patients With Aortic Arch Pathology and Their Impact on the Feasibility of Double and Triple Branched Endografts
Becker, D., Tsilimparis, N., Ali, A. A., Stana, J., Mihály, Z., Pichlmaier, M. A., Peterß, S., & Prendes, C. F. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.06.012 · Cited by 5
“26 Study ﬁ ndings also showed a positive correlation be-tween both height and BSA with an increasing PLZ length.”
The One Size Fits All EVAR Follow Up Has Proven Unsuccessful and Is a Thing of the Past
Gonçalves, F. B., & Wanhainen, A. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.03.018 · Cited by 5
Cardiovascular pathology, inheritance and prognosis in a familial cohort of Loeys-Dietz type III
Kay, R. T., Gouda, P., & Welsh, R. C. (2024) · International Journal of Cardiology · doi:10.1016/j.ijcard.2024.131984 · Cited by 4
Genetics in the diagnosis and treatment of cardiovascular diseases
Bliden, K. P., Singh, S. T., Shanoada, R., Kalia, I., Tantry, U. S., Zimmerman, A., Babu, A. D., Raghavakurup, L., Stude, T., Sidorski, D., et al. (2024) · Journal of Translational Genetics and Genomics · doi:10.20517/jtgg.2023.59 · Cited by 4
Linear growth pattern can be used to predict ascending aortic aneurysm growth
Viitala, I.-M., Selander, T. A., Hedman, M., & Turtiainen, J. (2024) · Scandinavian Cardiovascular Journal · doi:10.1080/14017431.2024.2430001 · Cited by 4
Low rates of aortic surveillance imaging and clinical follow-up in patients with acute aortic dissection
Flanagan, C. P., Kim, A. S., Ramirez, J. L., Mangipudi, S., Smith, E. J. T., Conte, M. S., & Hiramoto, J. S. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.12.041 · Cited by 4
Isotropic, high-resolution, whole-chest inversion recovery contrast-enhanced magnetic resonance angiography in under 4.5 min using image-based navigator fluoro trigger
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BackgroundMethod
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Influential
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Authors: Isselbacher, E. M., Preventza, O., Hamilton Black, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Schuyler Jones, W., Kalahasti, V., Kim, K. M., Milewicz, D. M., Oderich, G. S., Ogbechie, L., Promes, S. B., Gyang Ross, E., Schermerhorn, M. L., Singleton Times, S., Tseng, E. E., Wang, G. J., Woo, Y. J., Faxon, D. P., Upchurch, G. R., Aday, A. W., Azizzadeh, A., Boisen, M., Hawkins, B., Kramer, C. M., Luc, J. G. Y., MacGillivray, T. E., Malaisrie, S. C., Osteen, K., Patel, H. J., Patel, P. J., Popescu, W. M., Rodriguez, E., Sorber, R., Tsao, P. S., & Santos Volgman, A.
Affiliations: SCA representative.
ACR representative.
American Heart Association (US)
Lay stakeholder representative.
Fraunhofer Institute for Algorithms and Scientific Computing (DE)
AATS representative.
American Hospital Association (US)
AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.
STS representative.
SVS representative.
AHA/ACC staff representative.
ORCID: Isselbacher, Eric M.
Preventza, Ourania
Augoustides, John G.
Beck, Adam W.
Bolen, Michael A.
Braverman, Alan C.
Bray, Bruce E.
Chen, Edward P.
DeAnda, Abe
Fanola, Christina L.
Girardi, Leonard N.
Hicks, Caitlin W.
Hui, Dawn S.
Kalahasti, Vidyasagar
Kim, Karen M.
Milewicz, Dianna M.
Oderich, Gustavo S.
Promes, Susan B.
Schermerhorn, Marc L.
Tseng, Elaine E.
Upchurch, Gilbert R.
Aday, Aaron W.
Azizzadeh, Ali
Boisen, Michael
Kramer, Christopher M.
Luc, Jessica G.Y.
MacGillivray, Thomas E.
Osteen, Kathryn
Patel, Himanshu J.
Patel, Parag J.
Popescu, Wanda M.
Sorber, Rebecca
Tsao, Philip S.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2022-12-13
Volume: 146
Issue: 24
Pages: e334-e482
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000001106
PMC: PMC9876736
OpenAlex: W4307934708
Cited by: 2,082
References: 1,104
Citations by year: 2026: 600 · 2025: 569 · 2024: 554 · 2023: 348 · 2022: 9
FWCI: 239.09
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
Locations: Circulation (publishedVersion, cc-by)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Veterans Affairs
American Heart Association
Massachusetts General Hospital
American College of Cardiology Foundation
University of Pennsylvania
CryoLife
Office of Science
National Institute of Diabetes and Digestive and Kidney Diseases (K23DK124515)
Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Anschutz Medical Campus
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
Health Sciences › Medicine › Surgery › Aortic aneurysm repair treatments
Keywords: aortic disease, thoracic aortic disease, acute aortic syndrome, aortic aneurysm, aortic dissection, bicuspid aortic valve disease, peripheral arterial disease, genetic evaluation, family screening, endovascular repair, aortic surgery, long-term surveillance, shared decision-making, pregnancy
MeSH terms: Bicuspid Aortic Valve Disease, American Heart Association, Aortic Diseases, Cardiology, Female, Humans, Pregnancy, United States, Research Report

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