Cited by 2,082Aortic Disease and Treatment ApproachesConnective tissue disorders researchAortic aneurysm repair treatments

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2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

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Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Gyang Ross, Elsie, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., Santos Volgman, Annabelle·2022·Circulation

DOI 10.1161/cir.0000000000001106PMC PMC9876736

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Abstract

AIM: The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes). METHODS: A comprehensive literature search was conducted from January 2021 to April 2021, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through June 2022 during the guideline writing process, were also considered by the writing committee, where appropriate. Structure: Recommendations from previously published AHA/ACC guidelines on thoracic aortic disease, peripheral artery disease, and bicuspid aortic valve disease have been updated with new evidence to guide clinicians. In addition, new recommendations addressing comprehensive care for patients with aortic disease have been developed. There is added emphasis on the role of shared decision making, especially in the management of patients with aortic disease both before and during pregnancy. The is also an increased emphasis on the importance of institutional interventional volume and multidisciplinary aortic team expertise in the care of patients with aortic disease.

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Reproducibility of the 2020 Society for Vascular Surgery/Society of Thoracic Surgeons Reporting Standards for Uncomplicated Type B Aortic Dissection
Sriprachyakul, A., Mastrodicasa, D., Willemink, M. J., Mistelbauer, G., Shen, J., Yang, I. Y., Hallett, R. L., Malik, S. B., Madani, M. H., Lai, K. M., et al. (2025) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.240325 · Cited by 3
2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging: A Report of the ACC Competency Management Committee
Baldassarre, L. A., Mendes, L. A., Blankstein, R., Hahn, R. T., Patel, A. R., Russell, R. R., Abbara, S., Ahmad, S. M., Brady, M. B., Bullock-Palmer, R. P., et al. (2025) · Circulation Cardiovascular Imaging · doi:10.1161/hci.0000000000000088 · Cited by 5
Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA /Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing
Song, Q., Chu, T., Liu, Q., Weng, R., Li, H., Liang, M., & Wu, Z. (2025) · The FASEB Journal · doi:10.1096/fj.202502457r · Cited by 3
BMAL1 insufficiency increases the risk of thoracic aortic aneurysm and dissection
Song, W., Fu, G., Li, Q., Huo, C., Xiao, L., Liu, M., Zhang, X., Sun, H., Shen, K., Shi, L., et al. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvaf259 · Cited by 3
Patient Characteristics and Outcomes of Cardiac Rehabilitation Following Thoracic Aortic Dissection Surgery: A Multicenter Retrospective Study
Heybati, K., Ochal, D., Poudel, K., Zuberi, E. C., Deng, J., Taylor, B. J., Dineen, E. H., Brahmbhatt, P. M., Daugherty, D. H., Farres, S., et al. (2025) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000982 · Cited by 3
PRKG1 pathogenic variants cause thoracic aortic dissection with minimal aortic dilation: Insights from the UTHealth Houston multidisciplinary aortic and vascular disease conference
Askari, A., Landes, J. R., Cecchi, A. C., Duran, C., Zhao, B., Oderich, G. S., Buja, L. M., Milewicz, D. M., Estrera, A. L., Afifi, R. O., et al. (2025) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2025.102088 · Cited by 3
Editor's Choice – The Prevalence of Abdominal Aortic Aneurysm in First Degree Relatives: A Systematic Review and Meta-analysis
Fattahi, N., Stenman, M., & Hultgren, R. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.12.044 · Cited by 3
Current Understanding on Hypertensive Disorders in Pregnancy
Liao, J., & Zhu, Y. (2026) · International Journal of General Medicine · doi:10.2147/ijgm.s569466 · Cited by 6
Mechanistic Insight into PVAT Browning as a Protective Factor in Thoracic Aortic Aneurysm
Mu, W., Wang, Z., Chen, Y. E., & Chang, L. (2026) · Current Atherosclerosis Reports · doi:10.1007/s11883-025-01373-0 · Cited by 3
Animal Models of Aortic Aneurysm and Dissection: A Comparative Guide for Mechanism, Therapeutic Testing, and Translational Readouts
Mohammadmoradi, S., & Whiteheart, S. (2026) · Biomedicines · doi:10.3390/biomedicines14010170 · Cited by 3
“Aortic aneurysms and dissections (AAD) remain among the most lethal vascular diseases worldwide [1–3].”
CTA of the adult native aorta: Everything you wanted to know (but were never told)
Vaz, A., Ramos, D. D. O. S., Reifegerste, C. P., Serra, V. C., & Araújo, L. R. (2026) · Clinical Imaging · doi:10.1016/j.clinimag.2026.110758 · Cited by 3
Sex‐Related Differences in Clinical Profile, Management, and Outcomes of Patients With Type A and B Acute Aortic Dissection: Observations From IRAD
Jackson, E., Carbone, A., Shalhub, S., Pai, C.-W., Ehrlich, M., Suzuki, T., Hughes, G. C., Bhan, A., Faizer, R. M., Cittadini, A., et al. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.124.037506 · Cited by 3
“9,10 Thus, there is an urgent need to improve sex-specific AAD care.”
Wall Shear Stress as a Modulator of Aortic Dissection: Mechanistic Insights from Patient-Specific Modeling and Organ-on-a-Chip Validation
Zhao, X., Shen, H., Liu, Z., Wu, Y., Chen, B., Yao, J., Zheng, L., (13940), R. Z., Lin, M., Zhang, H., et al. (2026) · Research · doi:10.34133/research.1212 · Cited by 4
Transcatheter Aortic Valve Replacement for Severe Bicuspid Aortic Valve Stenosis
Ahn, J., Kumar, S., Ko, E., Mohammed, G., Hayashida, K., Yin, W., Jilaihawi, H., Makkar, R., Kim, W.-K., Palmerini, T., et al. (2026) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.125.016014 · Cited by 3
Using bioinformatic tools to identify high-risk variants of uncertain significance in aortopathy genes that increase aortic dissection risk
DePaolo, J. S., Guo, D., Murdock, D. R., Cecchi, A. C., LeMaire, S. A., Shen, H. Y., Estrera, A. L., Safi, H. J., Coselli, J. S., Smith, J. K., et al. (2026) · Genetics in Medicine · doi:10.1016/j.gim.2026.102571 · Cited by 3
Association between Pre-operative Aneurysm Diameter and One Year Sac Behaviour following Endovascular Aneurysm Repair
van Galen, I. F., Guetter, C. R., Darling, J. D., Caron, E., Davis, R. B., Patel, V. I., O’Donnell, T. F. X., Hazenberg, C. E. V. B., van Herwaarden, J. A., & Schermerhorn, M. L. (2026) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2026.04.004 · Cited by 3
Ten-year outcomes of valve-replacing versus valve-sparing aortic root replacement in patients with Marfan syndrome: An observational multicenter study
Coselli, J. S., Miller, D. C., Volguina, I. V., Murrieta-Álvarez, I., Green, S. Y., Sundt, T. M., Girardi, L. N., Desai, N. D., Connolly, H. M., Borger, M. A., et al. (2026) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2026.04.044 · Cited by 3
The global burden of calcified aortic valve stenosis: epidemiology, risk factors, disparities, and future perspectives – a narrative review
Hemelrijk, K. I., Delewi, R., Mehran, R., & Boekholdt, S. M. (2026) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2026.120731 · Cited by 5
Effects of cardiac function alterations on the risk of postoperative thrombotic complications in patients receiving endovascular aortic repair
Sun, X., Li, S., He, Y., Liu, Y., Ma, T., Zeng, R., Liu, Z., Chen, Y., Zheng, Y., & Liu, X. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2022.1114110 · Cited by 3
Pre-Test Probability Assessment and d-Dimer Based Evaluation in Patients with Previous Acute Aortic Syndrome
Morello, F., Santoro, M., Giachino, F., Caciolli, F., Capretti, E., Castelli, M., Pivetta, E. E., Nazerian, P., & Lupia, E. (2023) · Medicina · doi:10.3390/medicina59030548 · Cited by 3
Bicuspid aortic valve and its ascending aortopathy
Dunne, E. C., Lacro, R. V., & Flyer, J. N. (2023) · Current Opinion in Pediatrics · doi:10.1097/mop.0000000000001276 · Cited by 3
Perspectives on the 2022 joint guidelines on the diagnosis and management of aortic disease
Hui, D. S., Chen, E. P., DeAnda, A., Girardi, L. N., Kim, K. M., Woo, Y.-P. J., Tseng, E. E., & Preventza, O. A. (2023) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2023.07.046 · Cited by 3
Preoperative diameters of aorta influence the remodeling after surgery for type A aortic dissection
Zhang, L., Yang, S., Gao, H., & Xu, S. (2023) · Journal of Thoracic Disease · doi:10.21037/jtd-23-266 · Cited by 3
Prevalence of Genetically Triggered Aortopathy in Acute Aortic Syndrome in Aotearoa New Zealand
Haran, C., Ghafouri, K., Xu, W., Hayes, I., Stiles, M. K., & Khashram, M. (2023) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2023.09.013 · Cited by 3
Transcatheter Aortic Valve Therapy for Bicuspid Aortic Valve Stenosis
Dayawansa, N. H., Noaman, S. Q., Teng, L. E., & Htun, N. (2023) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd10100421 · Cited by 3
A Multidisciplinary Protocolized Approach for Ruptured Abdominal Aortic Aneurysm Management: A Retrospective Before-After Study
Yunus, R. A., Saeed, S., Levy, N., Fenza, R. D., Sharkey, A. M., Pobywajlo, S., Liang, P., Schermerhorn, M. L., Mahmood, F. U., Matyal, R., et al. (2023) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2023.12.015 · Cited by 3
Initial thickness of the crescent may not be a reliable predictor of complications in type A intramural haematoma
Kitamura, T., Shikata, F., Torii, S., Mishima, T., Fukuzumi, M., Motoji, Y., Tamura, Y., Kaneda, S., Ishiwaki, D., & Miyaji, K. (2024) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezae006 · Cited by 3
Biventricular interaction and aortic function in adult patients with repaired tetralogy of Fallot: a two-dimensional–three-dimensional speckle-tracking echocardiographic study
Vitarelli, A., Capotosto, L., Miraldi, F., Mukred, K., Francone, M., Galea, N., Mangieri, E., Tanzilli, G., Viceconte, N., Mancone, M., et al. (2024) · European Heart Journal - Imaging Methods and Practice · doi:10.1093/ehjimp/qyae015 · Cited by 3
Case Report: Role of numerical simulations in the management of acute aortic syndromes
Rizza, A., Castiglione, V., Capellini, K., Palmieri, C., Gasparotti, E., Berti, S. L., & Celi, S. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1309840 · Cited by 3
Endovascular aneurysm repair under local anesthesia through bilateral percutaneous femoral access is a safe strategy to improve early outcomes and reduce hospital stay
Esposito, D., on behalf of the Italian Collaborators for EVAR (ICE) Group, Fargion, A. T., Dorigo, W., Melani, C., Mauri, F., Zacà, S., Pratesi, G., Piffaretti, G., Angiletta, D., et al. (2024) · International Angiology · doi:10.23736/s0392-9590.24.05134-4 · Cited by 3
Cardiovascular and obstetrical outcomes among delivering patients with Marfan or Loeys-Dietz syndrome: a retrospective analysis by hospital delivery setting
Whelan, A., Thorsen, M. M., MacCarrick, G. L., & Russo, M. L. (2024) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2024.101340 · Cited by 3
Lowest reported dose area product of 2.4 Gy∗cm2 for ultra-low-dose endovascular aortic aneurysm repair of a standard infrarenal aortic aneurysm
Reeg, A., Braun, Y., Sunderbrink, D., & Hakimi, M. (2024) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2024.101496 · Cited by 3
Aortoiliac occlusion mimicking cauda equina syndrome, a diagnostic dilemma: A case report and review of the literature
Alomayri, A. F., Basalamah, A. A., Alsaleh, A. A., Alreshood, S., & Aldakkan, A. (2024) · Surgical Neurology International · doi:10.25259/sni_1011_2023 · Cited by 3
“[11] Certain aspects of management, including distinguishing between embolism and thrombosis etiologies before surgery, the use of aortography, the best initial treatment modality, the preferred course of management, and the role of long-term or permanent anticoagulation, are subjects of debate.”
Background
Experience with aortic arch inclusion technique using artificial blood vessel for type A aortic dissection: an application study
Li, Q., Li, B., Xi, S., Li, Z., Zhu, Z., Jin, Z., Yang, F., & Liu, L. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-02741-8 · Cited by 3
Exploring Thoracic Aortic Graft Infection: A Comprehensive Review of Diagnosis and Treatment Options with a Management Strategy Algorithm
Sullivan, K. E. O., Casey, L., Sidhu, P., Graham, A. N. J., Austin, C., & Hunter, M. (2024) · Journal of Cardiac Surgery · doi:10.1155/2024/2821237 · Cited by 3
Emerging Trends in the Care of Type B Aortic Dissections
Eidt, J. F., Gucwa, A. L., Cha, E., Hohmann, S. E., & Vásquez, J. (2024) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2024.08.026 · Cited by 3
Comparison of Biomechanical and Microstructural Properties of Aortic Graft Materials in Aortic Repair Surgeries
Sun, H., Cheng, Z., Guo, X., Gu, H., Tang, D., & Wang, L. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15090248 · Cited by 3
“Aortic diseases including aortic dissection (AD), aortic aneurysm, and coarctation of the aorta among others can be life-threatening, and often require open-chest surgery to treat [1–3].”
Background
Vascular abnormalities not to miss on routine chest CT: A pictorial review
Jamieson, R., Kharabish, A. E., & Aržanauskaitė, M. (2024) · European Journal of Radiology · doi:10.1016/j.ejrad.2024.111833 · Cited by 3
Presente y futuro de la evaluación del riesgo aórtico en pacientes con enfermedad aórtica hereditaria
Teixidó‐Turà, G., Dux‐Santoy, L., Badia-Molins, C., Freire, J. L., Guala, A., Evangelista, A., González, I. F., & Rodríguez-Palomares, J. F. (2024) · Revista Española de Cardiología · doi:10.1016/j.recesp.2024.10.012 · Cited by 3
Conservative Treatment of Retrograde Aortic Dissection After Endovascular or Hybrid Repair of Descending Aorta Pathologies
Borghese, O., Vincenzoni, C., Nocerino, M., Mangiacotti, L. P., & Tshomba, Y. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.11.099 · Cited by 3
Echocardiographic analysis of abdominal aorta dimensions and their associations with demographic characteristics in a healthy population
Bodagh, H., Mohammadi, K., Yousefzadeh, A., Hoshmand, A., Toufan, M., & Rahimi, M. (2024) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2024.2445340 · Cited by 3
Quality of life in people with syndromic heritable thoracic aortic disease and their relatives: a qualitative interview based study
Velvin, G., Johansen, H., Aune, G., Fugl-Meyer, K. S., & Geirdal, A. Ø. (2025) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-024-03485-3 · Cited by 4
A Narrative Review of Biomarkers and Imaging in the Diagnosis of Acute Aortic Syndrome
Arslan, Ü., & Jalalzai, İ. (2025) · Diagnostics · doi:10.3390/diagnostics15020183 · Cited by 3
Variation in Layer-Specific Tear Properties of the Human Aorta Along Its Length and Circumference: Implications for Spatial Susceptibility to Dissection Initiation
Sokolis, D. P. (2025) · Journal of Biomechanical Engineering · doi:10.1115/1.4067912 · Cited by 3
Imaging for Thoracic Aortic Dissections and Other Acute Aortic Syndromes
McCarthy, F. H., & Burke, C. R. (2025) · Cardiology Clinics · doi:10.1016/j.ccl.2024.10.001 · Cited by 3
Influence of Surgical Expertise on Repair of Acute Type a Aortic Dissection in a Standardized Operative Setting
Piani, D., Sponga, S., Lechiancole, A., Gliozzi, G., Copetti, S., Semeraro, A., Auci, E., Bortolotti, U., Livi, U., & Vendramin, I. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14061819 · Cited by 3
“…team included 8 cardiac surgeons, among whom there were 3 ES and 5 NES, as previously defined according to the consistency of their volume activity [9]: ES performed at least 100 cardiac operations per year and a minimum of 7 ATAAD repairs, while NES were those in their first 10 years of practice…”
Giant ascending aortic aneurysm: A rare case report
Mitsali, T., Dewi, D. K., & Hilman, H. (2025) · Radiology Case Reports · doi:10.1016/j.radcr.2025.02.030 · Cited by 3
“While there is limited data, aiming for a more stringent systolic BP target of 120 mm Hg could be beneficial for certain patients who are not undergoing surgery [ 7 ].”
Influential
Special considerations in assisted reproductive technology for patients with cardiovascular disease
Cromack, S. C., Kalinowska, V., Boots, C. E., & Mendelson, M. A. (2025) · Fertility and Sterility · doi:10.1016/j.fertnstert.2025.03.021 · Cited by 3
Pregnancy-Related Heart Disease in the Emergency Department
Hodgson, N. R., Lindor, R. A., Monas, J., Heller, K., Kishi, P., Thomas, A., Petrie, C., Querin, L. B., Urumov, A., & Majdalany, D. S. (2025) · Journal of Personalized Medicine · doi:10.3390/jpm15040148 · Cited by 3
“Untreated acute aortic syndrome has extremely high mortality with rapidly increasing rates of 1–2% per every hour of missed management [31,32].”
Management of Acute Type A Aortic Dissection
Clothier, J. S., & Kobsa, S. (2025) · Cardiology Clinics · doi:10.1016/j.ccl.2025.01.003 · Cited by 3
Outcomes of fenestrated-branched endovascular aortic repair of thoracoabdominal aortic aneurysms in patients with heritable thoracic aortic diseases
Ribé, L., Kanamori, L. R., Schmid, B., Macedo, T. A., Mendes, B. C., Maximus, S., Huang, Y., Nasser, F., & Oderich, G. S. (2025) · JTCVS Techniques · doi:10.1016/j.xjtc.2025.04.025 · Cited by 3
Association Between Geriatric Nutritional Risk Index and Discharge Outcome after Elective Thoracic Endovascular Aortic Repair
Ouchi, T., Kato, N., Kato, H., Higashigawa, T., Ito, H., Nakajima, K., Chino, S., Tokui, T., Oue, K., Mizumoto, T., et al. (2025) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-025-04066-y · Cited by 3
Iatrogenic aortic dissection: Insights from the International Registry of Acute Aortic Dissection
Harris, K. M., Parikh, N. B., Nienaber, C. A., Woznicki, E. M., Evangelista, A., Schermerhorn, M. L., Ouzounian, M., Coselli, J. S., Pai, C.-W., Ehrlich, M. P., et al. (2025) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2025.05.011 · Cited by 3
Self-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: The SWEDEHEART Registry
Louca, A., Myredal, A., Alchay, M., Hagström, H., Ioanes, D., James, S. K., Koul, S. M., Rawshani, A., Redfors, B., Rück, A., et al. (2025) · Structural Heart · doi:10.1016/j.shj.2025.100680 · Cited by 3
Precision Ultrasound-guided Stem Cell Delivery for Vascular Repair in Aortic Diseases
Gao, Q., Xu, Q., Cao, X., Xian, X., Xu, Q., Zhang, C., & Yu, B. (2025) · Journal of Visualized Experiments · doi:10.3791/68433 · Cited by 3
Complicated acute type A aortic dissection and severe aortic atherosclerosis predict early mortality after frozen elephant trunk procedure
Detter, C., Bax, L., Panuccio, G., Kölbel, T., Kodolitsch, Y. V., Reichenspurner, H. C., Demal, T. J., & Brickwedel, J. (2025) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezaf213 · Cited by 3
Application of Machine Learning in the Prediction of the Acute Aortic Dissection Risk Complicated by Mesenteric Malperfusion Based on Initial Laboratory Results
Jin, Z., Dong, J., Yang, J. M., Li, C., Li, Z., Ye, Z., Li, Y., Li, Y., Li, Y., & Ji, Z. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm37827 · Cited by 3
Long-term outcomes of initial thoracic endovascular repair versus medical therapy in acute uncomplicated type B aortic dissection: real-world evidence from a nationwide claims database in Japan – a retrospective cohort study
Kimura, Y., Ohtsu, H., Yonemoto, N., Azuma, N., & Sase, K. (2025) · BMJ Surgery Interventions & Health Technologies · doi:10.1136/bmjsit-2024-000361 · Cited by 3
68 Ga-DOTATATE Measurements Predict Progression of Aortic Valve Calcification in Humans
Aldosoky, W., Abohashem, S., Goudot, G., Grewal, S., Qamar, I., Hanlon, E. C., Alani, O., Bellinge, J. W., Civieri, G., Osborne, M. T., et al. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.322779 · Cited by 3
Risk Factors for Access-Related Adverse Events Related to the Preclose Technique in Thoracic Endovascular Aortic Repair
Xie, Y., Qin, Y.-L., Ji, J.-J., Bai, Z., Zhao, G.-F., & Deng, G. (2023) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2023.03.002 · Cited by 3
Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
Badran, A., Elghazouli, Y., Shirke, M., Al‐Tawil, M., Harky, A., & Ohri, S. K. (2023) · Cureus · doi:10.7759/cureus.39102 · Cited by 3
Global trends in research of acute type a aortic dissection: A bibliometric analysis from 2002 to 2022
Qi, Z., Tang, R. N., Wang, Q.-G., Zeng, Y., Tan, L., & Tang, H. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e17955 · Cited by 3
Vascular Disease Patient Information Page: Genetic testing for inherited vascular diseases associated with aneurysm and dissection
MacCarrick, G. L., & Ratchford, E. V. (2023) · Vascular Medicine · doi:10.1177/1358863x231191823 · Cited by 3
Cannulation Strategies in Type A Aortic Dissection: Overlooked Details and Novel Approaches
Yadav, I., Saifullah, H., Mandal, A. K., Almadhoun, M. K. I. K., Elabadi, H. M. E., Eugène, M., Suleman, M., Himedan, H. O. B., Fariha, F., Ahmed, H., et al. (2023) · Cureus · doi:10.7759/cureus.46821 · Cited by 3
“Putting an emphasis on cerebral protection during arch surgery increases the likelihood of successful outcomes [10].”
Background
Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease
Rebello, K. R., Green, S. Y., Etheridge, G. M., Zhang, Q., Glover, V. A., Zea-Vera, R., Moon, M. R., LeMaire, S. A., & Coselli, J. S. (2023) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2023.10.012 · Cited by 3
Male-female differences in thoracic aortic diameters at presentation of acute type A aortic dissection
Meccanici, F., Bom, A. W., Knol, W. G., Gökalp, A. L., Thijssen, C. G. E., Bekkers, J. A., Geuzebroek, G. S. C., Mokhles, M. M., van Kimmenade, R. R. J., Budde, R. P. J., et al. (2023) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2023.101290 · Cited by 3
“Rapid aortic growth and additional risk factors are also important to take into account [7,8].”
BackgroundMethodInfluential
Twenty years’ experience of type B aortic dissections: a population-based national registry study from Finland
Toimela, J., Sedha, J., Hedman, M., Valtola, A., Selander, T. A., & Husso, A. (2023) · Interdisciplinary CardioVascular and Thoracic Surgery · doi:10.1093/icvts/ivad184 · Cited by 3
Treatment selection for thoracoabdominal aortic aneurysm repair: open or endovascular?
Tanaka, A., Smith, H. N., & Estrera, A. L. (2023) · Vessel Plus · doi:10.20517/2574-1209.2023.108 · Cited by 3
Extensive thoracoabdominal aortic aneurysm as initial presentation in Takayasu arteritis: case series and literature review
Jena, A. B., Mishra, S., Padhee, B., Jena, S. K., Ghosh, N., Padhan, P., Rout, N. K., & Sahoo, P. (2023) · European Heart Journal - Case Reports · doi:10.1093/ehjcr/ytad627 · Cited by 3
Impact of Genotype-Phenotype Interactions on Cardiovascular Function in Paediatric Loeys-Dietz Syndrome
Khodabakhshian, N., Howell, A. J., López, P. P., Hui, W., Mertens, L., & Guerra, V. (2023) · CJC Pediatric and Congenital Heart Disease · doi:10.1016/j.cjcpc.2023.12.003 · Cited by 3
A Case of Type B Aortic Dissection: The Role of Transesophageal Ultrasound Guidance in Thoracic Endovascular Aortic Repair
Trimarchi, G., Benedetti, G., Palmieri, C., & Rizza, A. (2023) · Journal of Cardiovascular Echography · doi:10.4103/jcecho.jcecho_64_23 · Cited by 3
Cinematic rendering of non-traumatic thoracic aorta emergencies: a new look at an old problem
Yasrab, M., Rizk, R. C., Chu, L. C. H., & Fishman, E. K. (2024) · Emergency Radiology · doi:10.1007/s10140-024-02204-6 · Cited by 3
Echogenomics: Echocardiography in Heritable Aortopathies
Hunter-Adamson, L., & Tierney, E. S. S. (2024) · Current Cardiology Reports · doi:10.1007/s11886-024-02024-7 · Cited by 3
Later aorta operation after aortic valve replacement for bicuspid aortic valve
Hachiro, K., Takashima, N., & Suzuki, T. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-02638-6 · Cited by 3
Complicated and Uncomplicated Isolated Abdominal Aortic Dissections Demonstrate Different Patient Characteristics and Outcomes
Dittman, J. M., Benyakorn, T., Mouawad, N. J., Zj, C., Etafo, J., Quiroga, E., Starnes, B. W., & Shalhub, S. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.01.006 · Cited by 3
A network meta-analysis comparing the efficacy and safety of thoracic endovascular aortic repair with open surgical repair and optimal medical therapy for type B aortic dissection
Ahmed, S. H., Hasan, S. U., Samad, S., Mushtaq, R., Usmani, S. U. R., Kumar, D., Atif, A. R., Timbalia, S. A., & Zubair, M. M. (2024) · JVS-Vascular Insights · doi:10.1016/j.jvsvi.2024.100068 · Cited by 3
Genetic aortopathies: a case-based approach to multidisciplinary program development
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Authors: Isselbacher, E. M., Preventza, O., Hamilton Black, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Schuyler Jones, W., Kalahasti, V., Kim, K. M., Milewicz, D. M., Oderich, G. S., Ogbechie, L., Promes, S. B., Gyang Ross, E., Schermerhorn, M. L., Singleton Times, S., Tseng, E. E., Wang, G. J., Woo, Y. J., Faxon, D. P., Upchurch, G. R., Aday, A. W., Azizzadeh, A., Boisen, M., Hawkins, B., Kramer, C. M., Luc, J. G. Y., MacGillivray, T. E., Malaisrie, S. C., Osteen, K., Patel, H. J., Patel, P. J., Popescu, W. M., Rodriguez, E., Sorber, R., Tsao, P. S., & Santos Volgman, A.
Affiliations: SCA representative.
ACR representative.
American Heart Association (US)
Lay stakeholder representative.
Fraunhofer Institute for Algorithms and Scientific Computing (DE)
AATS representative.
American Hospital Association (US)
AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.
STS representative.
SVS representative.
AHA/ACC staff representative.
ORCID: Isselbacher, Eric M.
Preventza, Ourania
Augoustides, John G.
Beck, Adam W.
Bolen, Michael A.
Braverman, Alan C.
Bray, Bruce E.
Chen, Edward P.
DeAnda, Abe
Fanola, Christina L.
Girardi, Leonard N.
Hicks, Caitlin W.
Hui, Dawn S.
Kalahasti, Vidyasagar
Kim, Karen M.
Milewicz, Dianna M.
Oderich, Gustavo S.
Promes, Susan B.
Schermerhorn, Marc L.
Tseng, Elaine E.
Upchurch, Gilbert R.
Aday, Aaron W.
Azizzadeh, Ali
Boisen, Michael
Kramer, Christopher M.
Luc, Jessica G.Y.
MacGillivray, Thomas E.
Osteen, Kathryn
Patel, Himanshu J.
Patel, Parag J.
Popescu, Wanda M.
Sorber, Rebecca
Tsao, Philip S.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2022-12-13
Volume: 146
Issue: 24
Pages: e334-e482
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000001106
PMC: PMC9876736
OpenAlex: W4307934708
Cited by: 2,082
References: 1,104
Citations by year: 2026: 600 · 2025: 569 · 2024: 554 · 2023: 348 · 2022: 9
FWCI: 239.09
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
Locations: Circulation (publishedVersion, cc-by)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Veterans Affairs
American Heart Association
Massachusetts General Hospital
American College of Cardiology Foundation
University of Pennsylvania
CryoLife
Office of Science
National Institute of Diabetes and Digestive and Kidney Diseases (K23DK124515)
Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Anschutz Medical Campus
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
Health Sciences › Medicine › Surgery › Aortic aneurysm repair treatments
Keywords: aortic disease, thoracic aortic disease, acute aortic syndrome, aortic aneurysm, aortic dissection, bicuspid aortic valve disease, peripheral arterial disease, genetic evaluation, family screening, endovascular repair, aortic surgery, long-term surveillance, shared decision-making, pregnancy
MeSH terms: Bicuspid Aortic Valve Disease, American Heart Association, Aortic Diseases, Cardiology, Female, Humans, Pregnancy, United States, Research Report

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