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2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines
Open accessAbstract
AIM: The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes). METHODS: A comprehensive literature search was conducted from January 2021 to April 2021, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through June 2022 during the guideline writing process, were also considered by the writing committee, where appropriate. Structure: Recommendations from previously published AHA/ACC guidelines on thoracic aortic disease, peripheral artery disease, and bicuspid aortic valve disease have been updated with new evidence to guide clinicians. In addition, new recommendations addressing comprehensive care for patients with aortic disease have been developed. There is added emphasis on the role of shared decision making, especially in the management of patients with aortic disease both before and during pregnancy. The is also an increased emphasis on the importance of institutional interventional volume and multidisciplinary aortic team expertise in the care of patients with aortic disease.
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“Medical therapy of hypertension for individuals with TS and aortic dilation should preferably include a beta-blocker, angiotensin receptor blocker (ARB), or both, which have been shown to prevent aortic dilation and aortic dissections in individuals with other aortopathy conditions.439”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [439]
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“In this context, applying the current absolute diameter thresholds for aortic dilation (>4.0 cm) or aneurysm (>4.5 cm) to adults with TS would almost certainly lead to delayed recognition of aortic disease.439”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [439]
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MethodThoracoabdominal aortic aneurysm: a journey through the distal aorta
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Exercise as Medicine: Evaluation and Prescription for Adults with Congenital Heart Disease
Leone, D. M., Buber, J., & Shafer, K. M. (2023) · Current Cardiology Reports · doi:10.1007/s11886-023-02006-1 · Cited by 2
Taofan, T., Adiarto, S., Dakota, I., Indriani, S., Afandy, J. E., Kartamihardja, A. H. A., Kang, S. G., & Sukmawan, R. (2024) · F1000Research · doi:10.12688/f1000research.140435.2 · Cited by 2
Mosbahi, S., Siepe, M., Desai, N. D., Pregaldini, F., Nucera, M., Berezowski, M., Kelly, J. J., Jiang, F., Zhao, Y. F., Szeto, W. Y., et al. (2024) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezae024 · Cited by 2
Research Progress on Aortic Root Aneurysms
Du, T., Wang, W.-T., Wang, Y., Piao, H., & Liu, K.-X. (2024) · Medical Science Monitor · doi:10.12659/msm.943216 · Cited by 4
Zhang, C., Zhang, H., Pu, J., Schoenhagen, P., Zhao, L., Qiao, H., Yang, B., Wu, W., Zhang, C., Wang, R., et al. (2024) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-23-379 · Cited by 2
Lei, J., Qiu, P., Wu, Z., Ding, A., Hu, J., Hou, J., Jiang, Y., Pu, H., Huang, Q., Zhang, X. Y., et al. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.108071 · Cited by 2
Beckmann, E., Martens, A., Krueger, H., Korte, W., Shrestha, P., Kaufeld, T., & Shrestha, M. L. (2024) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezae046 · Cited by 2
The Lone Cusp: A Patient With a Regurgitant Unicuspid Valve With Aortic Aneurysm
Harb, A. M., Salah, A., ADEYEMI, B., Fatumnbi, O., Harb, A., Kumar, R. B., & Malaisrie, S. C. (2024) · CASE · doi:10.1016/j.case.2023.12.020 · Cited by 2
Initial Triage and Management of Patients with Acute Aortic Syndromes
Applefeld, W. N., & Jentzer, J. C. (2024) · Cardiology Clinics · doi:10.1016/j.ccl.2024.02.007 · Cited by 2
Aortic events and relative survival in patients with moderately dilated proximal thoracic aorta
Carlestål, E., Franco‐Cereceda, A., & Olsson, C. (2024) · Scandinavian Cardiovascular Journal · doi:10.1080/14017431.2024.2330345 · Cited by 2
Kang, M., Li, Y., Zhang, Y., Zhao, Y., Meng, Y., Zhang, J., & Tian, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-58106-7 · Cited by 2
Nnake, C. O., Concepción-González, A., Malka, M. S., Berube, E., Ferris, A. M., Bainton, N. M., Vitale, M. G., & Roye, B. D. (2024) · Journal of Pediatric Orthopaedics · doi:10.1097/bpo.0000000000002692 · Cited by 2
“3,19,21 It is important to note that in this study the fi nding of root or valve anomalies on echocardiogram, did not alter the anesthetic plan, nor lead to any problems during the postoperative course; thus, the abnormal preoperative echocardiogram did not contribute to management or surgical risk…”
Lv, Z. T., Pan, T., Zhang, H., Wang, Y., Matniyaz, Y., Tang, Y., Lu, L., & Wang, D. (2024) · Trials · doi:10.1186/s13063-024-08093-x · Cited by 2
Angerer, M., Pollari, F., Hitzl, W., Weber, L., Sirch, J., & Fischlein, T. J. M. (2024) · The Thoracic and Cardiovascular Surgeon · doi:10.1055/s-0044-1782186 · Cited by 2
Outcomes Following Different Management of Mycotic Infrarenal Abdominal Aortic Aneurysms
Lin, R., He, H., Zhao, Y., Lv, J.-B., Peng, J.-X., & Yin, H. (2024) · Journal of Endovascular Therapy · doi:10.1177/15266028241253128 · Cited by 2
Chong, A., Stanton, T., Taylor, A., Prior, D., Gerche, A. L., Anderson, B. A., Scalia, G. M., Cooke, J. C., Dahiya, A., To, A. C. Y., et al. (2024) · Heart Lung and Circulation · doi:10.1016/j.hlc.2023.11.028 · Cited by 3
2023 Update on Vascular Anesthesia
Smeltz, A. M., Newton, E. J., Kumar, P. A., Isaak, R. S., Doyal, A. S., Fernando, R. J., Vanneman, M. W., & Augoustides, J. G. (2024) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2024.05.011 · Cited by 2
Iyanna, N., Ogami, T., Yokoyama, Y., Takagi, H., Serna-Gallegos, D. R., Chu, D., Sultan, I. S., & Kuno, T. (2024) · The Journal of Cardiovascular Surgery · doi:10.23736/s0021-9509.24.12855-8 · Cited by 2
Chiariello, G. A., Mauro, M. D., Pasquini, A., Bruno, P., Nesta, M., Fabiani, L., Mazza, A., Meloni, M., Baldo, E., Ponzo, M., et al. (2024) · Interdisciplinary CardioVascular and Thoracic Surgery · doi:10.1093/icvts/ivae100 · Cited by 2
Meng, D., Wang, Y., Zhou, T., Gu, R., Zhang, Z., Zhao, T., He, H., Min, Y., & Wang, X. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1364361 · Cited by 2
Aortic root dilation in acromegaly
Yeboah-Kordieh, Y., Arif, W., Weisman, D., & Salvatori, R. (2024) · BMJ Case Reports · doi:10.1136/bcr-2024-260204 · Cited by 2
Brie, D. A., Jianu, A. M., Popescu, R., Cerbulescu, T., Dema, S., Brie, D., & Borugă, V. M. (2024) · Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie · doi:10.47162/rjme.65.2.11 · Cited by 2
Tanaka, A., Sandhu, H. K., Nguyen, H., Mills, A., Kiser, K., Afifi, R. O., Zhou, S. F., Miller, C. C., Safi, H. J., & Estrera, A. L. (2024) · JTCVS Techniques · doi:10.1016/j.xjtc.2024.07.018 · Cited by 2
Chen, Y., Ren, J., Liu, Z., Cui, D., Wang, S., Bi, J., & Dai, X. (2024) · Vascular · doi:10.1177/17085381241273233 · Cited by 2
Haunschild, J., Wiktorowska, P., Eifert, S., Stepan, H., Dähnert, I., Borger, M. A., & Etz, C. D. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13164901 · Cited by 2
Acute Type A aortic dissection surgical repair in Octogenarians: A meta-analysis
Hasan, M. T., Rezq, H. S., Saleh, O. M., Aboeldahab, H. A., khashab, M. K. E., Hamouda, S. M., Elkersh, H., Gbreel, M. I., Hassaballa, A. S., & Awad, A. K. (2024) · npj Cardiovascular Health · doi:10.1038/s44325-024-00007-9 · Cited by 2
Jiang, Y., Punjabi, K. P., Pierce, I., Knight, D. S., Yao, T., Steeden, J. A., Hughes, A. D., Muthurangu, V., & Davies, R. H. (2024) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2024.110253 · Cited by 2
A comprehensive organ protection strategy in total arch replacement: a propensity-weighted analysis
Zhou, S., Liu, Y., Zhang, B., Wang, L., Zhao, R., Xie, M., Chen, X., Dun, Y., & Sun, X. (2024) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezae385 · Cited by 2
Dang, H. N. N., Luong, T. V., Quan, N. K., Nguyen, U. N. P., Pham, N. N. K., Tran, H. T. N., Tran, H. K., Cao, M. T. T., Ho, B. A., Doan, T. C., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305799 · Cited by 2
Type A intramural hematoma over 21 years: A single center's experience
Kim, J. L., Baiocchi, M., Leipzig, M. M., Duda, M. M., Aranda-Michel, E. C., Tognozzi, E., Higa, K., Zhu, Y., MacArthur, J. W., Woo, Y.-P. J., et al. (2024) · JTCVS Open · doi:10.1016/j.xjon.2024.09.033 · Cited by 2
Kailash, K. A., Akanda, S. R., Davis, A. L., Crandall, C. L., Castro, L. A., Setton, L. A., & Wagenseil, J. E. (2024) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-024-01897-5 · Cited by 2
Grubb, K. J., Tom, S., Xie, J. X., Kalra, K., & Camaj, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13216565 · Cited by 2
Li, Y., Wu, T., Saeed, M. M., & Cui, X.-N. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1416349 · Cited by 2
Pruidze, P., Weninger, J. T., Didava, G., Schwendt, K. M., Geyer, S. H., Neumayer, C., Nanobachvili, J., Eilenberg, W. H., Czerny, M., & Weninger, W. J. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1475084 · Cited by 2
Expression Profile of TGFB1 Gene in Pediatric Patients with Isolated Bicuspid Aortic Valve
Eras, N., Çetinkaya, A., Giray, D., Hallıoğlu, O., & Aras, N. (2024) · Pediatric Cardiology · doi:10.1007/s00246-024-03733-0 · Cited by 2
Endovascular treatment of postoperative aortic coarctation aneurysms—a single center experience
Dimitrova, I. N., & Simeonov, P. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1441867 · Cited by 2
The Impact of Physical Activity on Abdominal Aortic Aneurysm: A Scoping Review
Malm, I. Å., Nilsson, P. V., & Hurtig‐Wennlöf, A. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.12.053 · Cited by 4
Are current follow-up intervals justified in patients with non-emergent aortic surgeries?
Kletzer, J., Berger, T., Kondov, S., Bleile, T., Dimov, A., Werdecker, V., Czerny, M., Rylski, B., & Kreibich, M. (2024) · Interdisciplinary CardioVascular and Thoracic Surgery · doi:10.1093/icvts/ivae226 · Cited by 2
Bradley‐Watson, J., Glatzel, H., Turner, H. E., & Orchard, E. (2025) · Clinical Endocrinology · doi:10.1111/cen.15199 · Cited by 2
Liu, S., Bian, X., Liu, Q., Zhang, R., Song, C., Yuan, S., Wang, H., Liu, W., Gao, J., Cui, X., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-093757 · Cited by 2
Rong, L. Q., Chun, S., Villar-Calle, P., Reza, M., Leshem, E., Falco, G., Kim, J. J., Devereux, R. B., & Weinsaft, J. W. (2025) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2025.01.038 · Cited by 2
One‐Year Functional Outcome of Patients After Surgery for Acute Stanford Type A Aortic Dissection
Yıldız, M., Nucera, M., Mosbahi, S., Münker, K. A., Kapkin, C., Jungi, S., Siepe, M., & Schoenhoff, F. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.036495 · Cited by 2
Preoperative Imaging of the Thoracic Aorta
Kirshenboim, Z. E., Önder, Ö., Duman, E., Elgendy, A. M., Yun, G., & Tavakoli, S. (2025) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2024.12.003 · Cited by 2
Núñez-Ordoñez, N., Senosiain, J., Umana, J. P., Amado-Olivares, A. F., Villa-Hincapié, C. A., Obando, C., & Camacho, J. (2024) · Aorta · doi:10.1055/s-0045-1802993 · Cited by 2
Bacour, N., Grewal, S., Tirpan, A. U., Theijse, R. T., van Erp, O., Klautz, R. J. M., Sakalihasan, N., Hultgren, R., & Grewal, N. (2024) · Aorta · doi:10.1055/a-2524-4772 · Cited by 2
Giant cell arteritis: Role of surgery in the management of vascular complications
Greigert, H., Bamdé, C., Ramon, A., Steinmetz, E. F., Béjot, Y., Bouchot, O., Bonnotte, B., & Samson, M. (2025) · Joint Bone Spine · doi:10.1016/j.jbspin.2025.105862 · Cited by 2
Nadel, J., Rodríguez-Palomares, J. F., Phinikaridou, A., Prieto, C., Masci, P. G., & Botnar, R. M. (2025) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2025.101865 · Cited by 2
Chen, Q., Jiang, Y., Feng, K., & Shan, Z. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2025.02.002 · Cited by 2
Jin, I. T., Ko, Y., Lee, S. J., Ahn, C., Lee, S., Lee, Y., Hong, S., Kim, J., Kim, B., Choi, D., et al. (2025) · Journal of Endovascular Therapy · doi:10.1177/15266028251320510 · Cited by 2
Genetic Counseling for Cardiovascular Disease: Part A – Pre-Test Approaches and Considerations
Goehringer, J., Sanoudou, D., & Morales, A. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1007908 · Cited by 2
Eremia, I. A., Popa, M.-I.-G., Anghel, C.-A., Stroe, T., Eremia, E.-A., Marinescu, A. N., Nica, R. I., & Nica, S. (2025) · Life · doi:10.3390/life15030462 · Cited by 2
“These findings emphasize the necessity of customized strategies in emergency care to enhance patient survival and recovery.”
Initial aortic repair versus medical therapy for early uncomplicated type B dissections
Teh, J. S., Chen, J., Kuo, Y.-T., Huang, C.-Y., Chen, T.-W., Shih, C.-C., & Hsu, C. (2025) · PLoS ONE · doi:10.1371/journal.pone.0319561 · Cited by 2
Wang, L., Liu, Y., Zhang, S., Li, J., Cui, Y., Yun, Y., Ma, X., & Zhang, H. (2025) · European journal of medical research · doi:10.1186/s40001-025-02475-w · Cited by 2
The impact of ascending aorta dilatation on transcatheter aortic valve implantation outcomes
Saputra, P. B. T., Widiarti, W., Mustofa, A., Savitri, C. G., Putranto, J. N. E., Ashari, F. Y., Multazam, C. E. C. Z., Alkaff, F. F., & D’Oria, M. (2025) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2025.101680 · Cited by 2
“In addition, higher diameter of ascending aorta is associated with higher mortality, such as less prevalent cases of aortic ascending aneurysms when ascending aortic diameter is ≥ 45 mm [6].”
Kanoksirirat, S., & Nithimathachoke, A. (2025) · Open Access Emergency Medicine · doi:10.2147/oaem.s496279 · Cited by 2
Penetrating Aortic Ulcers and Pseudoaneurysms Managed with Endovascular Aortic Arch Repair
Nana, P., Apostolidis, G., Torrealba, J. I., Panuccio, G., Spanos, K. T., & Kölbel, T. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2025.06.011 · Cited by 2
The Year in Aortic Surgery: Selected Highlights from 2024
Fernando, R. J., Coleman, S. R., Kothari, P., Vanneman, M. W., Kimlinger, M. J., Ochieng, P. O., Alghanem, F., Sanders, J. A., & Augoustides, J. G. (2025) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2025.06.031 · Cited by 2
Pedroza, A. J., Dalal, A. R., Kim, J. L., Duda, M. M., Tognozzi, E., Gilles, C., Miller, D. C., & Fischbein, M. P. (2025) · JTCVS Open · doi:10.1016/j.xjon.2025.06.013 · Cited by 2
Association Between Social Vulnerability and Clinical Outcomes After Proximal Aortic Surgery
Harik, L., Leith, J., Rahouma, M., Cancelli, G., Rossi, C. S., Soletti, G. J., Balaram, S. K., Lau, C., Girardi, L. N., & Gaudino, M. F. L. (2025) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezaf217 · Cited by 2
Endovascular Treatment for Aortic Diseases: Intercontinental Disparities
Naik, G., Wadiwala, I. J., & Hiremath, N. (2025) · Current Cardiology Reports · doi:10.1007/s11886-025-02260-5 · Cited by 2
Delayed diagnosis of aortic dissection: the overlooked clues on chest X-ray
Chen, Y., Wang, W., Lin, L., & Tang, Z. (2025) · International Journal of Emergency Medicine · doi:10.1186/s12245-025-00971-8 · Cited by 2
AortaAnalyzer: Interactive, integrated CTA aorta segmentation and quantitative analysis platform
von Deylen, F., Eulzer, P., & Lawonn, K. (2025) · Computers & Graphics · doi:10.1016/j.cag.2025.104415 · Cited by 2
Wehking, F., Lewejohann, J., & Bürckenmeyer, F. (2025) · Clinical Case Reports · doi:10.1002/ccr3.70684 · Cited by 2
Acute type A dissection with iliofemoral or renal malperfusion: Is frozen elephant trunk necessary?
Nissen, A. P., Reul, R. M., Naeem, M. W., Zurcher, J. R., Farrington, W. J., Keeling, W. B., & Leshnower, B. G. (2025) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2025.09.014 · Cited by 2
Lowenkamp, M. N., Nassereldine, H., Iams, A., Tzeng, E., & Reitz, K. M. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.09.054 · Cited by 2
“21 In our second sensitivity analysis, we defined OMT as only antiplatelet therapy and statin prescriptions, which are dependent only on provider action and not patient compliance.”
Syrengela, A.-A., Shahjahan, S., Bulut, H., Ttofi, I., Djordjevic, J., & Krasopoulos, G. (2023) · Journal of Surgery · doi:10.29011/2575-9760.001818 · Cited by 2
Abdominal Aortic Aneurysm (AAA)
Debus, E. S., & Grundmann, R. T. (2023) · Springer eBooks · doi:10.1007/978-3-031-47397-5_5 · Cited by 2
A Giant Transsternal Aortic Pseudoaneurysm
Sénéchal, I., Dagenais, F., & Beaudoin, J. (2023) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2023.01.028 · Cited by 2
Developing improved mathematical models of aortic mechanics
Rajagopal, K. R., Myneni, M., Trevino, A., Benjamin, C. C., Muthupillai, R., & Rajagopal, K. (2023) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2023.02.004 · Cited by 2
Night-time surgery for type a aortic dissection: Immediate or delaying?
Sichong, Q., Liu, H., Shipan, W., Yuan, X., Li, H., & Zhang, H. (2023) · Perfusion · doi:10.1177/02676591231164879 · Cited by 2
Medical Management of Cardiovascular Disease
Steiger, K. G., Pérez, A. F., & Erben, Y. (2023) · Surgical Clinics of North America · doi:10.1016/j.suc.2023.04.019 · Cited by 2
Current review of acute type A aortic dissection in Malaysia
Moorthy, P. S. K., Sakijan, A. S., Permal, D., Gaaffar, I. F., Kepli, A. S., & Sahimi, H. I. (2023) · Indian Journal of Thoracic and Cardiovascular Surgery · doi:10.1007/s12055-023-01608-2 · Cited by 2
Feng, W., & Xiao, Y. (2023) · PubMed Central · doi:10.11817/j.issn.1672-7347.2023.230078 · Cited by 2
Vervoort, D., Boodhwani, M., Chu, M. W. A., Chung, J. C.-Y., Appoo, J. J., & Ouzounian, M. (2024) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2024.101457 · Cited by 2
Velandia-Sánchez, A., Polania-Sandoval, C. A., Senosiain, J., Álvarez-Martínez, J. V., Gallo‐Bernal, S., Barrera-Carvajal, J. G., Umana, J. P., & Camacho, J. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-02793-w · Cited by 2
Complex aortic plaques: hidden danger in aortic stenosis. Role of transesophageal echocardiography
Benites‐Yshpilco, L., Cupe‐Chacalcaje, K., Cachicatari-Beltrán, Á., Moscoso, J., Velarde‐Acosta, K., Demarini-Orellana, A., Lévano-Pachas, G., & Baltodano‐Arellano, R. (2024) · Archivos Peruanos de Cardiología y Cirugía Cardiovascular · doi:10.47487/apcyccv.v5i2.377 · Cited by 2
Vicario-Feliciano, R. M., Zil‐E‐Ali, A., & Aziz, F. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.07.104 · Cited by 2
Skalidis, I., Antiochos, P., & Arangalage, D. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae704 · Cited by 2
ACC/AHA Aortic Disease Guidelines
Bonaca, M. P., & Olin, J. W. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.11.007 · Cited by 2
Editorial: Advances in aortic imaging
Leach, J., Zhu, C., Burris, N., & Hope, M. D. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1137949 · Cited by 2
Glycoprotein VI is Critical for the Detection and Progression of Abdominal Aortic AneurysmsPreprint
Benson, T. W., Pike, M., Spuzzillo, A. R., Hicks, S. M., Pham, M., Mix, D., Brunner, S. I., Wadding-Lee, C., Conrad, K. A., Russell, H. M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.02.547361 · Cited by 2
BEST3-Mediated MEKK2/3 Activation: A Novel Therapeutic Target in Aortopathies
Sawada, H., & Daugherty, A. (2023) · Circulation · doi:10.1161/circulationaha.123.065946 · Cited by 2
Refining the course: long-term outcome in patients with bicuspid aortic valve
Backer, J. F. A. D., & Prakash, S. K. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad621 · Cited by 2
Overview of contemporary guidelines for management of acute type A aortic dissection
Mehta, C. K., Medina, M. G., Whippo, B. A., & Malaisrie, S. C. (2024) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2024.05.019 · Cited by 2
Aortic dissection after transcatheter aortic valve replacement
DeRoo, S. C., & George, I. (2024) · JTCVS structural and endovascular. · doi:10.1016/j.xjse.2024.100009 · Cited by 2
Platelets are Protective in Early Abdominal Aortic Aneurysm FormationPreprint
Russell, H., Spuzzillo, A. R., Benson, T. W., Jaworski, J., Clément, M., Boulaftali, Y., Saum, K. L., Conrad, K. A., Howatt, D. A., Luyendyk, J. P., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.29.616205 · Cited by 2
Angiotensin II Induces Abdominal Aortic Branch Aneurysms in Fibrillin-1 C1041G/+ MicePreprint
Franklin, M., Howatt, D. A., Moorleghen, J. J., Sheppard, M. B., Katsumata, Y., Sawada, H., Lu, H. S., & Daugherty, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.26.690689 · Cited by 2
“( C ) Tissue sections of the celiac and superior mesenteric aortic branches were stained with Verhoeff’s iron hematoxylin, picrosirius red/methyl green, and immunostained for -smooth muscle actin and CD68, respectively.”
Wang, H., Chen, S., Zhong, Y., Ge, Y., Qiao, Z.-Y., Li, C., Guo, R.-T., Zhang, Z., Qiao, C., & Zhu, J. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-067469 · Cited by 1
Metadata
- Authors
- Isselbacher, E. M., Preventza, O., Hamilton Black, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Schuyler Jones, W., Kalahasti, V., Kim, K. M., Milewicz, D. M., Oderich, G. S., Ogbechie, L., Promes, S. B., Gyang Ross, E., Schermerhorn, M. L., Singleton Times, S., Tseng, E. E., Wang, G. J., Woo, Y. J., Faxon, D. P., Upchurch, G. R., Aday, A. W., Azizzadeh, A., Boisen, M., Hawkins, B., Kramer, C. M., Luc, J. G. Y., MacGillivray, T. E., Malaisrie, S. C., Osteen, K., Patel, H. J., Patel, P. J., Popescu, W. M., Rodriguez, E., Sorber, R., Tsao, P. S., & Santos Volgman, A.
- Affiliations
- SCA representative.
- ACR representative.
- American Heart Association (US)
- Lay stakeholder representative.
- Fraunhofer Institute for Algorithms and Scientific Computing (DE)
- AATS representative.
- American Hospital Association (US)
- AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.
- STS representative.
- SVS representative.
- AHA/ACC staff representative.
- ORCID
- Isselbacher, Eric M.
- Preventza, Ourania
- Augoustides, John G.
- Beck, Adam W.
- Bolen, Michael A.
- Braverman, Alan C.
- Bray, Bruce E.
- Chen, Edward P.
- DeAnda, Abe
- Fanola, Christina L.
- Girardi, Leonard N.
- Hicks, Caitlin W.
- Hui, Dawn S.
- Kalahasti, Vidyasagar
- Kim, Karen M.
- Milewicz, Dianna M.
- Oderich, Gustavo S.
- Promes, Susan B.
- Schermerhorn, Marc L.
- Tseng, Elaine E.
- Upchurch, Gilbert R.
- Aday, Aaron W.
- Azizzadeh, Ali
- Boisen, Michael
- Kramer, Christopher M.
- Luc, Jessica G.Y.
- MacGillivray, Thomas E.
- Osteen, Kathryn
- Patel, Himanshu J.
- Patel, Parag J.
- Popescu, Wanda M.
- Sorber, Rebecca
- Tsao, Philip S.
- Venue
- Circulation
- Published
- 2022-12-13
- Volume
- 146
- Issue
- 24
- Pages
- e334-e482
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC9876736
- OpenAlex
- W4307934708
- Cited by
- 2,082
- References
- 1,104
- Citations by year
- 2026: 600 · 2025: 569 · 2024: 554 · 2023: 348 · 2022: 9
- FWCI
- 239.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Circulation (publishedVersion, cc-by)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Veterans Affairs
- American Heart Association
- Massachusetts General Hospital
- American College of Cardiology Foundation
- University of Pennsylvania
- CryoLife
- Office of Science
- National Institute of Diabetes and Digestive and Kidney Diseases (K23DK124515)
- Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Anschutz Medical Campus
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Medicine › Surgery › Aortic aneurysm repair treatments
- Keywords
- aortic disease, thoracic aortic disease, acute aortic syndrome, aortic aneurysm, aortic dissection, bicuspid aortic valve disease, peripheral arterial disease, genetic evaluation, family screening, endovascular repair, aortic surgery, long-term surveillance, shared decision-making, pregnancy
- MeSH terms
- Bicuspid Aortic Valve Disease, American Heart Association, Aortic Diseases, Cardiology, Female, Humans, Pregnancy, United States, Research Report
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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