Cited by 2,082Aortic Disease and Treatment ApproachesConnective tissue disorders researchAortic aneurysm repair treatments

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2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

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Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Gyang Ross, Elsie, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., Santos Volgman, Annabelle·2022·Circulation

DOI 10.1161/cir.0000000000001106PMC PMC9876736

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Abstract

AIM: The "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease" provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes). METHODS: A comprehensive literature search was conducted from January 2021 to April 2021, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through June 2022 during the guideline writing process, were also considered by the writing committee, where appropriate. Structure: Recommendations from previously published AHA/ACC guidelines on thoracic aortic disease, peripheral artery disease, and bicuspid aortic valve disease have been updated with new evidence to guide clinicians. In addition, new recommendations addressing comprehensive care for patients with aortic disease have been developed. There is added emphasis on the role of shared decision making, especially in the management of patients with aortic disease both before and during pregnancy. The is also an increased emphasis on the importance of institutional interventional volume and multidisciplinary aortic team expertise in the care of patients with aortic disease.

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Rizza, A., Negro, F., Mandigers, T. J., Palmieri, C., Berti, S. L., & Trimarchi, S. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20054094 · Cited by 3
The Call for the “Interventional/Hybrid” Aortic Surgeon: Open, Endovascular, and Hybrid Therapies of the Aortic Arch
Vervoort, D., An, K. R., Deng, M. X., Elbatarny, M., Fremes, S. E., Ouzounian, M., & Tarola, C. L. (2023) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2023.11.038 · Cited by 3
Pregnancy-related aortic dissection—recognize, mitigate, act
Lim, M., & Braverman, A. C. (2023) · Annals of Cardiothoracic Surgery · doi:10.21037/acs-2023-adw-11 · Cited by 3
Challenges and Innovations in Postoperative Care for Acute Type A Aortic Dissection: The Role of Structured Surveillance and Virtual Wards
Pruna‐Guillen, R., Ghosh, L., Mastracci, T. M., Kapil, V., López-Marco, A., & Oo, A. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2511389 · Cited by 3
Age-related difference in acute type B aortic dissection
Zhang, Z., Lin, F., Huang, X., He, Z., Wang, H., & Cheng, T. (2023) · Vascular · doi:10.1177/17085381231214720 · Cited by 2
Looking after the cardiac surgery patient: pitfalls and strategies
Evans, B., & Haqzad, Y. S. (2024) · Surgery (Oxford) · doi:10.1016/j.mpsur.2023.12.012 · Cited by 2
Current techniques of repair of aortic arch pathologies and the role of the aortic team
Lodo, V., & Centofanti, P. (2024) · Indian Journal of Thoracic and Cardiovascular Surgery · doi:10.1007/s12055-024-01704-x · Cited by 2
Surgically induced aortic coarctation in a neonatal porcine model allows for longitudinal assessment of cardiovascular changes
Stellon, M., Gober, L., Culver, M. A., Hermsen, J. L., Irrer, D., Witzenburg, C. M., Roldán‐Alzate, A., & Lamers, L. J. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00087.2024 · Cited by 2
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis
Hassab, A. H. M., Hur, D. J., Vallabhajosyula, P., Tellides, G., & Assi, R. (2024) · JCI Insight · doi:10.1172/jci.insight.172437 · Cited by 2
“…little relevance in patient management and may explain why limited tears are not included in recent reviews of acute aortic syndrome and clinical practice guidelines for the diagnosis and management of aortic disease (1, 28), whereas these lesions were previously recognized by the authors (5, 49).”
Influential
Micro-robotic percutaneous targeting of type II endoleaks in the angio-suite
Widmann, G., Deeg, J., Frech, A., Klocker, J., Feuchtner, G. M., & Freund, M. C. (2024) · International Journal of Computer Assisted Radiology and Surgery · doi:10.1007/s11548-024-03195-y · Cited by 2
Correlation analysis of gamma-glutamyl transferase to lymphocyte ratio and patients with acute aortic syndrome in China: a propensity score-matched analysis
Li, M., Xu, W., Chen, H., Lai, Y., Chen, Y., Shu, Z., & Tan, X. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1333153 · Cited by 2
Methylation Levels in the 5' Region of the TBX20 Gene in the Ascending Aorta Change in Opposite Direction in Atherosclerosis and Aneurysm
Koroleva, I. A., Goncharova, I. A., Зарубин, А. А., Shipulina, S. А., Слепцов, А. А., Панфилов, Д. С., Kozlov, B. N., & Nazarenko, M. S. (2024) · Russian Journal of Genetics · doi:10.1134/s102279542470042x · Cited by 2
Surgical technical experience of adult aortic coarctation concomitant with poststenotic aneurysm or dissection
Qiao, H., Yang, B., Rotzinger, D. C., & Liu, Y. (2024) · Journal of Thoracic Disease · doi:10.21037/jtd-24-985 · Cited by 2
A Morphological Indicator for Aortic Dissection: Fitting Circle of the Thoracic Aorta
Pu, H., Peng, T., Xu, Z., Sun, Q., Wang, Z., Ma, H., Fang, S., Yang, Y., Wu, J., Wang, R., et al. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-04130-4 · Cited by 2
Computed Tomography Imaging Measurements as a Surrogate for Clinical Outcomes After Surgical Management of Acute Type A Aortic Dissection: A Systematic Review
Vo, T. X., Rahmouni, K., Visintini, S., Guo, M. H., Ouzounian, M., Chu, M. W. A., Boodhwani, M., Appoo, J. J., Tucker, K., Al‐Atassi, T., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.124.034496 · Cited by 2
Feasibility of endovascular aortic arch repair after hemiarch replacement for acute type A aortic dissection
Lella, S. K., Eagleton, M. J., Sundt, T. M., Srivastava, S. D., Hosseini, M., Bloom, J. P., Kreso, A., Melnitchouk, S. I., Mohebali, J., & Jassar, A. S. (2024) · JTCVS structural and endovascular. · doi:10.1016/j.xjse.2024.100026 · Cited by 2
Clinical effectiveness of genetic testing guidelines in patients with thoracic aortic aneurysms
Erez, E., Higaki, A. R. A., Cupo, M., Phu, T. A., Verma, S., Assi, R., & Vallabhajosyula, P. (2024) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2024.09.026 · Cited by 2
Quantitative Electroencephalography Monitoring in Type A Aortic Dissection Surgery: A Clinical Case Review and Prospective Applications
Wang, Y., Qu, J. Z., & Wang, D. (2024) · Brain and Behavior · doi:10.1002/brb3.70086 · Cited by 2
Utilization of percutaneous closure devices for large bore arterial access in patients with genetic aortopathy does not result in increased rates of access site complications
Sorber, R. A., Smerekanych, S., Pang, H. J., Murphy, B. E., Dansey, K. D., Sweet, M. P., & Zettervall, S. L. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.11.001 · Cited by 2
Aortopathy in repaired tetralogy of Fallot and David procedure
Ichikawa, N., Shiina, Y., Abe, K., & Niwa, K. (2024) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-24-264 · Cited by 2
“Current American and European guidelines for the management of aortic diseases recommend valve-sparing surgery over valve replacement, especially in younger patients and when performed at experienced centers (4,5).”
Present and future of aortic risk assessment in patients with heritable thoracic aortic diseases
Teixidó‐Turà, G., Dux‐Santoy, L., Badia-Molins, C., Freire, J. L., Guala, A., Evangelista, A., González, I. F., & Rodríguez-Palomares, J. F. (2024) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2024.10.009 · Cited by 2
Comparison of clinical outcomes between Castor single-branched stent graft and in situ fenestration in treating Stanford type B aortic dissection involving the left subclavian artery: A retrospective case-control study
Weng, X., Zhang, T., Hu, Y., Li, X. Q., & Zhou, W. (2024) · Medicine · doi:10.1097/md.0000000000040623 · Cited by 2
Sympathetic Nerve Activity following Acute Type B Aortic Dissection: A Pilot Study
Lim, E. T. A., Jardine, D. L., FRAMPTON, C. M. A., Pemberton, C. J., Troughton, R. W., Roake, J., & Khanafer, A. (2024) · Journal of Vascular Research · doi:10.1159/000543340 · Cited by 2
Midterm Outcome of Aortic Dissection Associated With Aberrant Subclavian Artery: A Single-Center Retrospective Observational Study
Sun, Y., Gu, Y., Dong, S., Huang, L.-C., Shao, Z., Xu, H., Du, C., Dong, J., & Guo, H. (2024) · Journal of Endovascular Therapy · doi:10.1177/15266028241307568 · Cited by 2
Giant Cell Arteritis
Kermani, T. A. (2026) · Annals of Internal Medicine · doi:10.7326/annals-26-00531 · Cited by 2
Sexual Dimorphism in Abdominal Aortic Aneurysm—Insights from Clinical and Experimental Studies
Islam, Z. H., Mei, H., Tetz, Z., Kanchetty, R., Stanisic, S., Hoyt, N. E., Marcum, W. A., Johnston, C., Kent, E. W., Zhang, M., et al. (2025) · Journal of Vascular Diseases · doi:10.3390/jvd4010005 · Cited by 2
A Multidisciplinary Aortopathy Clinic: The McGill Experience
Kodaira, M., Lachapelle, K. J., Leask, R. L., Bates, K., Grossman, Y., Guerrero‐Chalela, C., Kennedy, L. P., Thanassoulis, G., Steinmetz, O. K., MacKenzie, K. S., et al. (2025) · CJC Open · doi:10.1016/j.cjco.2025.01.021 · Cited by 2
“4 Here, we present our 8-year experience with the McGill Aortopathy Clinic, providing an overview of its patient population and multifaceted functioning, along with considerations for future improvement.”
Chronic Post-Traumatic Aortic Isthmus Pseudoaneurysm After Conservative Management of Grade II Injury: Why Is Continuous Follow-Up Mandatory?
Sica, S., Tinelli, G., Borghese, O., Dimri, M., Dvir, M., Minelli, F., Rizza, A., Bruno, P., Massetti, M., & Tshomba, Y. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041133 · Cited by 2
“Continuous follow-up of these patients is mandatory, as it could allow for the early diagnosis of complications, optimizing the clinical outcomes.”
Aortic Atherosclerosis: An Updated Review of Current Guidelines and Management Approach—A Literature Review
Mubder, M. I., Dugal, J., Houshmand, N., & Tak, T. (2025) · International Journal of Angiology · doi:10.1055/a-2536-9215 · Cited by 2
Prediction Model of in Hospital Death for Stanford Type A Aortic Dissection Based on a Meta-Analysis of 24 Cohorts
Wang, Z., Zhao, Y., Guo, S., Liu, J., & Zhang, H. (2025) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2025.03.017 · Cited by 2
Anesthesia Management for the Personalized External Aortic Root Support (PEARS) Procedure: A Single-Center Experience
Pandey, A. K., Kougioumtzoglou, A. M., Lam, B. C. Y., Kho, E., Eberl, S., Dilai, J., Koolbergen, D. R., & Hermanns, H. (2025) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2025.03.047 · Cited by 2
Case Report: Unlocking arteria Lusoria challenges: sternotomy's role in a single-stage aneurysm repair and artery realignment
Gunga, Z., Rousseau, L., Wolff, M., Rigollot, A., Nowacka, A., Dulgorov, F., Ltaief, Z., Rancati, V., Trunfio, R., Déglise, S., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1557293 · Cited by 2
Performance and costs of rule-out protocols for acute aortic syndromes: analysis of pooled prospective cohorts
Bima, P., Nazerian, P., Mueller, C. E., Castelli, M., Capretti, E., Soeiro, A. D. M., Cipriano, A., Costantino, G., Vanni, S., Leidel, B. A., et al. (2025) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2025.03.039 · Cited by 2
“If the ADD or AORTAs score value is ≤ 1, the PP is considered low, and DD testing is used for decision on CTA [11,12].”
Immediate transcatheter aortic valve replacement versus temporizing balloon aortic valvuloplasty in severe aortic stenosis: A systematic review and meta-analysis immediate TAVR vs. temporizing BAV
Doma, M., Huang, W., Hernandez, S., Fatima, S. R., Lingamsetty, S. S. P., Kritya, M., Hemdanieh, M., Naji, Z., Gewehr, D. M., Martignoni, F., et al. (2025) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2025.04.019 · Cited by 2
Proximal Landing Zone’s Impact on Outcomes of Branched and Fenestrated Aortic Arch Repair
Nana, P., Spanos, K. T., Panuccio, G., Torrealba, J. I., Rohlffs, F., Detter, C., Kodolitsch, Y. V., & Kölbel, T. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14103288 · Cited by 2
“However, However, The latest guidelines for aortic disease from the American Heart Association and American College of Cardiology suggest endovascular aortic arch treatment in high-risk patients with adequate anatomy [11].”
Influential
Next frontier in endovascular aortic therapy: An anatomic analysis of feasibility of endovascular treatment of ascending thoracic aortic aneurysms
Qiu, Y., Appoo, J. J., Herget, E. J., Demers, P., Tseng, E. E., Jassar, A. S., Chu, M. W. A., Moon, M. C., & Boodhwani, M. (2025) · JTCVS structural and endovascular. · doi:10.1016/j.xjse.2025.100056 · Cited by 2
Prediction of tissue rupture from percolation of local strain heterogeneities for diagnostics
Schütte, F., Friebe, S., Böttcher, D., Borger, M. A., Uhlemann, M., & Mayr, S. G. (2025) · Communications Medicine · doi:10.1038/s43856-025-00897-5 · Cited by 2
Intra-aortic infusion of nicotine can induce a novel mouse model of abdominal aortic aneurysm.
Liu, H., Qin, L., Zou, J., Tian, K.-L., Li, K., Tian, R., Malik, F., Wei, P., Xia, C., Hou, H., et al. (2025) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2025.107143 · Cited by 2
Simple Renal Cysts in Marfan Syndrome
Bouleti, C., Tence, N., Thuillier, R., Nicot, F., Pasi, N., Alos, B., Suc, G., Milleron, O., Arnoult, F., Tchitchinadze, M., et al. (2025) · JACC Advances · doi:10.1016/j.jacadv.2025.101870 · Cited by 2
A Systematic Review of Anti-TNF and Anti-IL-6 Treatments for Pediatric Takayasu Arteritis: Addressing a Therapeutic Dilemma
Batu, E. D., & Şener, S. (2025) · Pediatric Drugs · doi:10.1007/s40272-025-00706-5 · Cited by 2
“In the AHA [10] and EULAR [9] guidelines, no preference was stated between anti-TNF drugs or anti-IL-6, while anti-TNF treatment was preferred over anti-IL-6 in the ACR 2021 guideline [8].”
Development and validation of a novel prognostic score to improve prognostic prediction in patients with type B aortic dissection
Chen, X., Xie, L., Wu, Q., Luo, S., Wang, Z., Jiang, Y., Lin, X., Han, X., Qiu, Z., & Chen, L. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.06.018 · Cited by 2
Incidental floating aortic mass as the initial presentation of primary aortic sarcoma
Huerta, L. D. J., Shershaby, S. S. E., Arellano, C. E., & Salar, R. C. (2025) · BMJ Case Reports · doi:10.1136/bcr-2024-264423 · Cited by 2
Simultaneous 3D aortic lumen and vessel wall imaging at 0. 55 T at either systole or diastole
Paredes, M., Castillo‐Passi, C., Kunze, K., Fotaki, A., Littlewood, S., Botnar, R. M., & Prieto, C. (2025) · Magnetic Resonance in Medicine · doi:10.1002/mrm.30611 · Cited by 2
Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection
Guo, S., Wang, Z., Zhao, Y., Guo, Y., Zhang, H., & Liu, J. (2025) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-025-03497-5 · Cited by 2
Complex endovascular arch repair using fenestrated and branched devices: a single-centre experience
Bastianon, M., Stana, J., Konstantinou, N., Khangoli, D., Peterß, S., Pichlmaier, M. A., & Tsilimparis, N. (2025) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezaf208 · Cited by 2
From Aneurysms to Dissections: A Transfer Learning Approach for CTA Segmentation
Magliocco, M., Basso, C., Fantazzini, A., Conti, M., Cittadini, G., & Spinella, G. (2025) · Proceedings - IEEE Symposium on Computer-Based Medical Systems · doi:10.1109/cbms65348.2025.00044 · Cited by 2
Thoracic endovascular aortic repair compared with medical treatment in patients with type B intramural hematoma
Wu, S., Yang, Y., Wang, J., Xin, Y.-J., Wang, J., Liang, H., Zheng, L., & Lyu, S. (2025) · VASA · doi:10.1024/0301-1526/a001215 · Cited by 2
Outcomes of routine surveillance of grade 1 blunt traumatic aortic injury
Zaidi, S. T., Koh, E. Y., Estrera, G. A., Wong, J. H., Puzio, T. J., Oderich, G. S., Estrera, A. L., & Saqib, N. U. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.07.035 · Cited by 2
Mortality in acute type A aortic dissection – A systematic review based on contemporary registries
Matei, D.-C., Robu, C., Ciobanu, C. G., Geavlete, O. D., Antohi, E., Radu, R. I., Bubenek, Ș., Iliescu, V. A., & Chioncel, O. (2025) · Romanian Journal of Internal Medicine · doi:10.2478/rjim-2025-0015 · Cited by 2
Tricuspid Aortic Valve Regurgitation Associates With Ascending Aortic Aneurysm Through Endothelial Activation and Lipoprotein Infiltration
Freiholtz, D., Reyes‐Goya, C., Lång, K., Bergman, O., Olsson, C., Koski, M. G., Dismorr, M., Österholm, C., Caidahl, K., Franco‐Cereceda, A., et al. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.323112 · Cited by 2
Instruction-Tuned Large Language Models for Clinical Data Extraction: Creating an Aortic Measurement Database from CT Radiology Reports
Erez, E., Dankwa, S., Tuttle, M. R., Nasir, A., Vallabhajosyula, P., Schneider, E. B., Assi, R., & Ong, C. S. (2025) · Journal of Healthcare Informatics Research · doi:10.1007/s41666-025-00210-y · Cited by 2
Deep learning-based detection of ascending aortic dilatation on chest radiographs: A diagnostic study
Lee, H., Park, G., Park, C., Ok, J., Lee, W., Kim, S. M., Wu, M.-T., & Choo, K. S. (2025) · European Journal of Radiology · doi:10.1016/j.ejrad.2025.112380 · Cited by 2
Institutional impact of multidisciplinary aortic team implementation on practice patterns and surgical productivity
Sorber, R. A., Byers, P. H., Schwarze, U., Buber, Y., Kirkpatrick, J. N., Otto, C. M., DeRoo, S. C., Zettervall, S. L., Burke, C. R., & Sweet, M. P. (2025) · Seminars in Vascular Surgery · doi:10.1053/j.semvascsurg.2025.09.001 · Cited by 2
Surgical experience and long-term outcomes of retrograde type A aortic dissection after thoracic endovascular aortic repair
Ji, Y., Zhang, K., Zhou, C., Gao, W. Q., Hou, B., Wang, J., Xu, K., Gao, S., Qiu, J., & Yu, C. (2025) · JTCVS Open · doi:10.1016/j.xjon.2025.09.006 · Cited by 2
Anatomic Suitability of Left Subclavian Artery Off-The-Shelf Branch Graft in a Real-World Setting
Blitti, C. M., Loucou, J. D., Laubriet, A., Bouchot, O., Bamdé, C., & Steinmetz, E. F. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2025.09.029 · Cited by 2
Incidental Cardiovascular Findings in Lung Cancer Screening and Noncontrast Chest Computed Tomography
Cham, M. D., & Shemesh, J. (2025) · Journal of Thoracic Imaging · doi:10.1097/rti.0000000000000853 · Cited by 2
Mapping 18F-FDG Positron Emission Tomography Uptake in the Aortic Wall and Thrombus: Validation and Reproducibility
Bragulat-Arévalo, M., Ferrer‐Cornet, M., Dux‐Santoy, L., Oliveró, R., García-Reyes, M., Teixidó‐Turà, G., Garrido-Oliver, J., Galián-Gay, L., López-Gutiérrez, P., Catalá-Santarrufina, A., et al. (2025) · Applied Sciences · doi:10.3390/app151910685 · Cited by 2
Popliteal Artery Aneurysm Morphology in Symptomatic and Asymptomatic Patients Undergoing Invasive Treatment
Jergovic, I., Cervin, A., Nordanstig, J., Nilsson, O., Roy, J., & Hultgren, R. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.09.066 · Cited by 2
Early and late outcomes of patient-specific endografts with retrograde outer branches for complex aortic aneurysms involving cranially oriented target vessels
Schmid, B., Kanamori, L. R., Abdelhalim, M. A., Vanmaele, A., Lima, G. B. B., Babocs, D., Nair, H. R., Huang, Y., Modarai, B., & Oderich, G. S. (2025) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2025.102004 · Cited by 2
What Echocardiographic Findings Suggest Acute Type A Aortic Dissection?
Alerhand, S., Qiu, L., & Adrian, R. J. (2025) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2025.10.012 · Cited by 2
Integrin αV emerges as a potential therapeutic target with cautionary implications in thoracic aortic aneurysm and dissection
Su, S., Zhu, Y., Feng, Z., Hu, Z., Le, J., Chen, C., Shen, J. F., Zhu, S., Wu, S., Ma, H., et al. (2025) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2025.10.006 · Cited by 2
A Systematic Review and Meta-Analysis on the Outcomes of Distal Aortic Interventions for Residual Aortic Dissection
Squizzato, F., Bilato, M. J., Menegolo, M., Colacchio, E. C., Grego, F., Piazza, M., & Antonello, M. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2025.09.060 · Cited by 2
High diagnostic yield of family echocardiographic screening of children with bicuspid aortic valve
Norsk, J. B., Raja, A. A., Pærregaard, M. M., Dannesbo, S., Kock, T. O., Vøgg, R. O. B., Vejlstrup, N., Iversen, K. K., Bundgaard, H., & Sillesen, A. (2025) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeaf293 · Cited by 2
Imaging lipid deposition induced by local hypoxia in degenerative aortic valve disease using a twisted intramolecular charge transfer (TICT)-based lipid droplet-targeting probe
Chai, Z., Chen, M., Qu, T., Zhang, Y., Li, S., Li, S., Zhuang, W., Wu, Y., Hu, W., & Chen, M. (2025) · Microchimica Acta · doi:10.1007/s00604-025-07613-z · Cited by 2
One-Year Results of Novel Aortic Arch Hybrid Prosthesis for Repair of Acute DeBakey Type I Dissection With Malperfusion: PERSEVERE Study
Szeto, W. Y., Fukuhara, S., Fleischman, F., Sultan, I. S., Brinkman, W. T., Arnaoutakis, G. J., Takayama, H., Eudailey, K. W., Jassar, A. S., Moon, M. C., et al. (2025) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2025.10.036 · Cited by 2
Diretriz Brasileira de Atendimento à Dor Torácica na Unidade de Emergência – 2025
Silva, P. G. M. D. B. E., Soeiro, A. D. M., Ornelas, C., Feitosa-Filho, G. S., Lópes, R. D., Lino, D. O. D. C., Furtado, R. H. D. M., Guimarães, H. P., Volschan, A., Gomes, B. F. D. O., et al. (2025) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20250620 · Cited by 30
Platelet defects in patients and mice with Ehlers-Danlos syndrome
Kumskova, M., Flora, G. D., Nayak, M. K., Budnik, I., Jain, A., Patel, R. B., Jha, A., Ghatge, M., Chauhan, N., Michael, J. V., et al. (2025) · Blood · doi:10.1182/blood.2025029912 · Cited by 2
Unmasking nonspecific pain – clinical clues and diagnostic challenges in acute aortic syndromes: Case series
Kočan, L., Rybár, D., Kolesár, A., Lukačín, Š., Šujanová, A., Galovičová, A., Židzik, J., & Vašková, J. (2025) · Medicine · doi:10.1097/md.0000000000046200 · Cited by 2
Genotype-aortic phenotype correlations in Marfan syndrome: a systematic review and meta-analysis of Fibrillin-1 variants
Korukonda, S., Byers, P. H., Kovuri, P., Dhanekula, A., Wilcox, K. T., & DeRoo, S. C. (2025) · Heart · doi:10.1136/heartjnl-2025-326810 · Cited by 2
Acute effects of aerobic exercise on aortic wall stress in thoracic aortic disease
Skow, R. J., Foulkes, S., Thompson, R. B., Grenier, J. G., Moulson, N., Niederseer, D., McKinny, J., Elefteriades, J. A., McMurtry, M. S., & Haykowsky, M. J. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00829.2025 · Cited by 2
From Single Cells to Targetable Immune Mechanisms in Congenital Heart Disease, Ischemic Heart Disease, and Abdominal Aortic Aneurysm
He, R., Kadyrov, F. F., Parvathaneni, A., Wu, G., & Lavine, K. J. (2026) · Circulation Research · doi:10.1161/circresaha.125.325794 · Cited by 3
Predictive value of machine learning for mortality risk in aortic dissection: a systematic review and meta-analysis
Han, Z., Li, B., & Liu, J. (2026) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2026.106271 · Cited by 2
Outcomes of Hemiarch Versus Zone 2 Arch Replacement for DeBakey Type I Aortic Dissection
Kelly, J. J., Gillinov, L. A., Zhao, Y. F., Sperry, A., Goel, N. J., Berezowski, M., Kapoor, S. R., Bavaria, J. E., Brown, C. R., Lawrence, K. M., et al. (2026) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezag006 · Cited by 2
Technical considerations and contemporary literature review of the Gore Thoracic Branch Endoprosthesis®
Schmid, B. P., Kanamori, L. R., Oden-Brunson, H., Babocs, D., Huang, Y., Miranda, J. A., Maximus, S., & Oderich, G. S. (2026) · The Journal of Cardiovascular Surgery · doi:10.23736/s0021-9509.25.13474-5 · Cited by 2
Ethnic variation in thoracic aortic dimensions in the general population: a comparison between Indian and Dutch populations
Bacour, N., Mohammed Idhrees, A., Samraj, J., Grewal, S., Velayudhan, B. V., Celik, N. B., Zafar, M. A., Elefteriades, J. A., & Grewal, N. (2026) · Open Heart · doi:10.1136/openhrt-2025-003808 · Cited by 2
Thoracic aortic aneurysm and dissection: Similarities, differences and pharmacotherapy
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Authors: Isselbacher, E. M., Preventza, O., Hamilton Black, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Schuyler Jones, W., Kalahasti, V., Kim, K. M., Milewicz, D. M., Oderich, G. S., Ogbechie, L., Promes, S. B., Gyang Ross, E., Schermerhorn, M. L., Singleton Times, S., Tseng, E. E., Wang, G. J., Woo, Y. J., Faxon, D. P., Upchurch, G. R., Aday, A. W., Azizzadeh, A., Boisen, M., Hawkins, B., Kramer, C. M., Luc, J. G. Y., MacGillivray, T. E., Malaisrie, S. C., Osteen, K., Patel, H. J., Patel, P. J., Popescu, W. M., Rodriguez, E., Sorber, R., Tsao, P. S., & Santos Volgman, A.
Affiliations: SCA representative.
ACR representative.
American Heart Association (US)
Lay stakeholder representative.
Fraunhofer Institute for Algorithms and Scientific Computing (DE)
AATS representative.
American Hospital Association (US)
AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.
STS representative.
SVS representative.
AHA/ACC staff representative.
ORCID: Isselbacher, Eric M.
Preventza, Ourania
Augoustides, John G.
Beck, Adam W.
Bolen, Michael A.
Braverman, Alan C.
Bray, Bruce E.
Chen, Edward P.
DeAnda, Abe
Fanola, Christina L.
Girardi, Leonard N.
Hicks, Caitlin W.
Hui, Dawn S.
Kalahasti, Vidyasagar
Kim, Karen M.
Milewicz, Dianna M.
Oderich, Gustavo S.
Promes, Susan B.
Schermerhorn, Marc L.
Tseng, Elaine E.
Upchurch, Gilbert R.
Aday, Aaron W.
Azizzadeh, Ali
Boisen, Michael
Kramer, Christopher M.
Luc, Jessica G.Y.
MacGillivray, Thomas E.
Osteen, Kathryn
Patel, Himanshu J.
Patel, Parag J.
Popescu, Wanda M.
Sorber, Rebecca
Tsao, Philip S.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2022-12-13
Volume: 146
Issue: 24
Pages: e334-e482
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000001106
PMC: PMC9876736
OpenAlex: W4307934708
Cited by: 2,082
References: 1,104
Citations by year: 2026: 600 · 2025: 569 · 2024: 554 · 2023: 348 · 2022: 9
FWCI: 239.09
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
Locations: Circulation (publishedVersion, cc-by)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Veterans Affairs
American Heart Association
Massachusetts General Hospital
American College of Cardiology Foundation
University of Pennsylvania
CryoLife
Office of Science
National Institute of Diabetes and Digestive and Kidney Diseases (K23DK124515)
Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Anschutz Medical Campus
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
Health Sciences › Medicine › Surgery › Aortic aneurysm repair treatments
Keywords: aortic disease, thoracic aortic disease, acute aortic syndrome, aortic aneurysm, aortic dissection, bicuspid aortic valve disease, peripheral arterial disease, genetic evaluation, family screening, endovascular repair, aortic surgery, long-term surveillance, shared decision-making, pregnancy
MeSH terms: Bicuspid Aortic Valve Disease, American Heart Association, Aortic Diseases, Cardiology, Female, Humans, Pregnancy, United States, Research Report

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