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Cited by 449

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Developing MicroRNA Therapeutics

van Rooij, Eva, Purcell, Angela L., Levin, Arthur A.·2012·Circulation Research
DOI 10.1161/circresaha.111.247916
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Abstract

Rarely a new research area has gotten such an overwhelming amount of attention as have microRNAs. Although several basic questions regarding their biological principles still remain to be answered, many specific characteristics of microRNAs in combination with compelling therapeutic efficacy data and a clear involvement in human disease have triggered the biotechnology community to start exploring the possibilities of viewing microRNAs as therapeutic entities. This review serves to provide some general insight into some of the current microRNAs targets, how one goes from the initial bench discovery to actually developing a therapeutically useful modality, and will briefly summarize the current patent landscape and the companies that have started to explore microRNAs as the next drug target.

Overview

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Crossref · 10.1161/circresaha.111.247916

Cites

9 of 9 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 42

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Metadata

Authors
van Rooij, E., Purcell, A. L., & Levin, A. A.
Affiliations
From miRagen Therapeutics, Inc, Boulder, CO (E.v.R.); Cooley LLP, Washington, DC (A.L.P.); and Santaris Pharma A/S, San Diego, CA (A.A.L.).
Venue
Circulation Research
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2012-02-03
Volume
110
Issue
3
Pages
496-507
ISSN
  • 0009-7330
  • 1524-4571
DOI
10.1161/circresaha.111.247916
Cited by
449
References
9
Language
en

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