The DOI matches its Crossref record; 205 of the 208 references it cites were found in a registry or an index.
Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk
Open accessAbstract
Aging and diabetes mellitus are 2 well-known risk factors for cardiovascular disease (CVD). During the past 50 years, there has been an dramatic increase in life expectancy with a simultaneous increase in the prevalence of diabetes mellitus in the older population. This large number of older individuals with diabetes mellitus is problematic given that CVD risk associated with aging and diabetes mellitus. In this review, we summarize epidemiological data relating to diabetes mellitus and CVD, with an emphasis on the aging population. We then present data on hyperglycemia as a risk factor for CVD and review the current knowledge of age-related changes in glucose metabolism. Next, we review the role of obesity in the pathogenesis of age-related glucose dysregulation, followed by a summary of the results from major randomized controlled trials that focus on cardiovascular risk reduction through glycemic control, with a special emphasis on older adults. We then conclude with our proposed model of aging that body composition changes and insulin resistance link possible dysregulation of physiological pathways leading to obesity and diabetes mellitus—both forms of accelerated aging—and risks for CVD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Many factors participate in the metabolic dysregulation that develops with increasing age, and changes in body composition make an important contribution (100).”
From Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus (2023) · cites this paper as [100]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
International Diabetes Federation 2017
Carracher, A. M., Marathe, P. H., & Close, K. L. (2018) · Journal of Diabetes · doi:10.1111/1753-0407.12644 · Cited by 13,379
2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Effects of Intensive Glucose Lowering in Type 2 Diabetes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0802743 · Cited by 7,888
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Neal, B., Perkovic, V., Mahaffey, K. W., de Zeeuw, D., Fulcher, G., Erondu, N., Shaw, W., Law, G., Desai, M., & Matthews, D. R. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1611925 · Cited by 7,830
10-year follow-up of intensive glucose control in type 2 diabetes
Holman, R. R., Paul, S. K., Bethel, M. A., Matthews, D. R., & Neil, H. A. W. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806470 · Cited by 7,751
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes
Marso, S. P., Daniels, G. H., Brown-Frandsen, K., Kristensen, P., Mann, J. F. E., Nauck, M. A., Nissen, S. E., Pocock, S., Poulter, N. R., Ravn, L. S., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1603827 · Cited by 7,629
Glucose clamp technique: a method for quantifying insulin secretion and resistance.
DeFronzo, R. A., Tobin, J. D., & Andres, R. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.237.3.e214 · Cited by 7,425
Research works printed but not linked: 4
- He, W, Goodkind, D, Kowal, P. An Aging World: 2015; International Population Reports. 2016. US Census Bureau, US Government Printing Office: Washington D.C.
- 10.1001/jama.1971.03190220020005 · DOI
- 10.1001/jama.1971.03190060017005 · DOI
- Knatterud, GL, Klimt, CR, Goldner, MG, Hawkins, BS, Weisenfeld, S, Kreines, K, Haddock, L. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes.V. Evaluation of phenformin therapy. Diabetes. 1975;24:65–184.
Cited by
Sorted by citations
Items 201–300 of 455
Geroprotective applications of oleuropein and hydroxytyrosol through the hallmarks of ageing
Calabrò, A., Aiello, A., Silva, P., Caruso, C., Candore, G., & Accardi, G. (2025) · GeroScience · doi:10.1007/s11357-025-01697-4 · Cited by 6
Management of Inpatient Hyperglycemia and Diabetes in Older Adults
Davis, G. M., DeCarlo, K., Wallia, A., Umpierrez, G. E., & Pasquel, F. J. (2020) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2020.04.008 · Cited by 8
Prevalence of hyperglycemia in masters athletes
Climstein, M., Walsh, J., Adams, K., Sevene, T. G., Heazlewood, T., & DeBeliso, M. (2022) · PeerJ · doi:10.7717/peerj.13389 · Cited by 6
Yang, J., Chen, E., Choi, C., Chan, K., Yang, Q., Rana, J., Yang, B. Y., Huang, C., Yang, A., & Lo, K. K.-H. (2022) · Nutrients · doi:10.3390/nu14193972 · Cited by 6
Genome-Wide Association Study on Longitudinal Change in Fasting Plasma Glucose in Korean Population
Jin, H., Kwak, S. H., Yoon, J. W., Lee, S., Park, K. S., Won, S., & Cho, N. H. (2023) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2021.0375 · Cited by 6
Altabas, V., Pukec, L., Mlinarić, S., Pintarić, H., & Šikić, A. (2020) · International Journal of Endocrinology · doi:10.1155/2020/3606757 · Cited by 7
Suharni, S., Kusnadi, D. T., & Zulkarnaini, A. (2022) · Scientific Journal · doi:10.56260/sciena.v1i2.38 · Cited by 6
Predicting hypoglycemia after treatment of hyperkalemia with insulin and glucose (Glu-K60 score)
Kijprasert, W., Tarudeeyathaworn, N., Loketkrawee, C., Pimpaporn, T., Pattarasettaseranee, P., & Tangsuwanaruk, T. (2022) · BMC Emergency Medicine · doi:10.1186/s12873-022-00748-9 · Cited by 7
Flake, C. C., Valenzuela, M., Tiongco, R. E., & Navarro, A. T. (2024) · The Egyptian Journal of Internal Medicine · doi:10.1186/s43162-024-00294-9 · Cited by 5
Pinaffi‐Langley, A. C. D. C., Pinto, C. B., Mukli, P., Péterfi, A., Kaposzta, Z., Owens, C. D., Szarvas, Z., Muranyi, M., Adams, C., Shahriari, A., et al. (2024) · PNAS Nexus · doi:10.1093/pnasnexus/pgae505 · Cited by 6
Törrönen, R., Järvinen, S., & Kolehmainen, M. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.08.026 · Cited by 7
Sahl, R. E., Patsi, I., Hansen, M. T., Rømer, T., Frandsen, J., Rasmusen, H. K., Ingersen, A., Poulsen, S. S., Dela, F., Larsen, S., et al. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad509 · Cited by 5
Karim, M. M., Sahin, M. A. Z., Seo, K., Park, D., Kim, K. B., & Shim, Y.-B. (2025) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2025.138485 · Cited by 4
Kynigopoulos, D., Fella, E., Shahabian, L., Christodoulou, C. C., Papacharalampous, R., Diskos, K., Vagiaki, L. E., Sidiropoulou, K., Pipis, M., Kleopa, K. A., et al. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1636624 · Cited by 4
Xi, Y., Breitner-Busch, S., Dong, Q., Wolf, K., Dallavalle, M., Nikolaou, N., Cyrys, J., Grallert, H., Linkohr, B., Rathmann, W., et al. (2026) · Environment International · doi:10.1016/j.envint.2025.110043 · Cited by 4
Li, X., Zhou, X. K., Chen, Y., & Liu, W. (2025) · BMC Cancer · doi:10.1186/s12885-025-14802-9 · Cited by 4
Tappo, S., Laohasiriwong, W., & Puttanapong, N. (2022) · Geospatial health · doi:10.4081/gh.2022.1091 · Cited by 4
Minderis, P., Fokin, A., Povilonis, T., Kvedaras, M., & Ratkevičius, A. (2023) · Nutrients · doi:10.3390/nu15224836 · Cited by 4
Ng, Y. H., Moy, F. M., Hairi, N. N., & Bulgiba, A. M. (2024) · PeerJ · doi:10.7717/peerj.16778 · Cited by 4
Sakurai, M., Motoike, I. N., Hishinuma, E., Aoki, Y., Tadaka, S., Kogure, M., Orui, M., Ishikuro, M., Obara, T., Nakaya, N., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-66180-0 · Cited by 4
Modeling sex-specific whole-body metabolic responses to feeding and fasting
Abo, S. M. C., & Layton, A. T. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.109024 · Cited by 5
Latorre‐Muro, P., Vitale, T., Ravichandran, M., Zhang, K., Palozzi, J. M., Bennett, C. F., Lamas‐Paz, A., Sohn, J. H., Jackson, T. D., Jedrychowski, M. P., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-024-01555-z · Cited by 5
Zheng, R., Zeng, X., Shen, R., Wang, Y., Liu, J., & Zhang, M. (2025) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s501132 · Cited by 4
Askeland-Gjerde, D. E., Westlye, L. T., Andersson, P., Korbmacher, M., de Lange, A. G., van der Meer, D., Smeland, O. B., Halvorsen, S., Andreassen, O. A., & Gurholt, T. P. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100488 · Cited by 3
Long-term neurodevelopmental outcomes among preterm infants born to mothers with diabetes mellitus
Sugar, J., Lum, T. G., Fertel, S., Yim, R., Morales, A., Poeltler, D. M., & Katheria, A. C. (2021) · Journal of Perinatology · doi:10.1038/s41372-021-01255-8 · Cited by 4
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
Liu, X., Khalil, A., Muthukumarasamy, U., Onogi, Y., Yan, X., Singh, I., Lopez-Gonzales, E., Israel, A., Cebrian-Serrano, A., Strowig, T., et al. (2023) · BMC Biology · doi:10.1186/s12915-023-01629-8 · Cited by 4
Qi, S., Yang, X., Zeng, K., Li, Y., & Ma, J. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s421984 · Cited by 5
Blanks, A. M., Pedersen, L. N., Caslin, H. L., Mihalick, V. L., Via, J. O., Canada, J. M., Tassell, B. W. V., Carbone, S., Abbate, A., & Franco, R. L. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2022.110077 · Cited by 4
HUBUNGAN INDEKS MASSA TUBUH, PERSEN LEMAK TUBUH, DAN AKTIVITAS FISIK DENGAN KADAR GULA DARAH REMAJA
Lisnawati, N., Kusmiyati, F., Herwibawa, B., Kristanto, B. A., & Rizkika, A. (2023) · Journal of Nutrition College · doi:10.14710/jnc.v12i2.36662 · Cited by 4
Madsong, C., Lininger, J., & Terathongkum, S. (2025) · Belitung Nursing Journal · doi:10.33546/bnj.3891 · Cited by 3
Chen, J., Fang, Y., Liu, Y., Chen, M., & Tsai, M. (2025) · Journal of the American Geriatrics Society · doi:10.1111/jgs.70187 · Cited by 5
Insulin as an Accelerator and Brake of Aging: From Molecular Landscape to Clinical Interventions
Chen, S., Sun, X., & Zhang, Y. (2025) · Comprehensive physiology · doi:10.1002/cph4.70079 · Cited by 4
Age-Stratified Differences in Cardio–Reno–Metabolic Risk Profiles
Popoviciu, M. S., & Ghitea, T. C. (2026) · Geriatrics · doi:10.3390/geriatrics11010018 · Cited by 3
Fournier, C., Karagounis, L. G., Sacco, S. M., Horcajada, M.-N., Decaens, T., Offord, E., Bouzakri, K., & Ammann, P. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.108952 · Cited by 3
Shimels, T., Bilal, A. I., Samuel, D., Gedamu, D., Solomon, E., & Shewamene, Z. (2024) · Venereology · doi:10.3390/venereology3020008 · Cited by 3
Aging and lung cancer: the role of macrophages
Yang, X., Gao, L., & Fu, D. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114676 · Cited by 6
Bae, J., Kim, S. H., Won, Y. J., & Kim, Y. M. (2022) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2021.0105 · Cited by 3
Kwon, D., Lee, W., Kim, S. H., & Jung, Y. (2022) · Metabolites · doi:10.3390/metabo12100910 · Cited by 3
Zhang, Z. W., Hua, Y., & Liu, A. P. (2023) · PubMed Central · doi:10.19723/j.issn.1671-167x.2023.03.012 · Cited by 3
Batsis, J. A., Batchek, D. J., Petersen, C. L., Gross, D. C., Lynch, D. H., Spangler, H., & Cook, S. B. (2023) · Nutrients · doi:10.3390/nu15234947 · Cited by 3
A new histopathological phenomenon: Pancreatic islet cell loss in the elderly population
Li, R., Yang, T., Zhang, M., Ren, K., Li, J., Sato, I., & Yi, S. (2023) · Digestive and Liver Disease · doi:10.1016/j.dld.2023.11.031 · Cited by 3
Kobayashi, R., & Negoro, H. (2024) · BioMed · doi:10.3390/biomed4010003 · Cited by 3
Schumock, G., Bandeen‐Roche, K., Chia, C. W., Kalyani, R. R., Ferrucci, L., & Varadhan, R. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302381 · Cited by 3
Self-citationChukwuemeka, O. E., Onah, C. E., Kalu, A. A., Okeke, C. S., Obiorah, O. M., Okezie, A. O., Ogalagu, R. O., Iwuji, J. C., Emmanuel, M. R., & Meludu, S. (2024) · Indian Journal of Forensic and Community Medicine · doi:10.18231/j.ijfcm.2024.013 · Cited by 3
Deng, B., Li, S., You, R., & Fu, Z. (2024) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2024.2418325 · Cited by 3
Dietary education provision within a cardiac rehabilitation programme in the UK: a pilot study
Moore, C., Tsakirides, C., Rutherford, Z. H., Swainson, M. G., Birch, K. M., Ibeggazene, S., & Ispoglou, T. (2020) · British Journal of Cardiac Nursing · doi:10.12968/bjca.2020.0012 · Cited by 3
Foucan, L., Afassinou, Y. M., Chingan-Martino, V., Ancédy, Y., Bassien-Capsa, V., Galantine, O., Nicolas, L., Tabué-Teguo, M., Martino, F., & Larifla, L. (2022) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2021.0027 · Cited by 3
CORONAVIRUS-RELATED ANXIETY WITH HYPERGLYCEMIA IN TYPE 2 DIABETES PATIENTS
Hikmah, K., Helda, H., & Killeen, C. (2022) · Jurnal Berkala Epidemiologi · doi:10.20473/jbe.v10i22022.111-120 · Cited by 3
Insulin and Ageing: Interventions for Healthier Lifestyle and Prolonged Lifespan
Chrysanthus, C. S. (2023) · Journal of BioMed Research and Reports · doi:10.59657/2837-4681.brs.23.006 · Cited by 3
Improvement in Glycemic Control in Mice of Different Age Groups
Gamage, S., Peddibhotla, S. S. D., Reddy, P. H., Dhurandhar, N. V., & Hegde, V. K. (2019) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-0961-7804 · Cited by 3
Bohari, B., Nuryani, N., Abdullah, R., Amaliah, L., & Hafid, F. (2021) · AcTion Aceh Nutrition Journal · doi:10.30867/action.v6i2.587 · Cited by 3
Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axisPreprint
Cikes, D., Leutner, M., Cronin, S. J. F., Novatchkova, M., Pfleger, L., Klepochová, R., Lair, B., Lac, M., Bergoglio, C., Viguerie, N., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.26.465828 · Cited by 3
Gutschmayer, S., Yu, J., Geist, B. K., Özer, Ö., Reiterits, B., Ferrara, D., Pires, M., Rausch, I., Ibeschitz, H., Karanikas, G., et al. (2025) · Scientific Data · doi:10.1038/s41597-025-05997-4 · Cited by 3
Wen, J., Hou, H., Hu, F., & Phau, I. (2026) · Asia Pacific Journal of Marketing and Logistics · doi:10.1108/apjml-01-2026-998 · Cited by 3
Joshi, N. K., Arora, V., Purohit, A., Lohra, A., Joshi, V., Shih, T., & Harsh, J. (2023) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_2273_22 · Cited by 3
Jokelainen, M., Kautiainen, H., Nenonen, A., Stach‐Lempinen, B., & Klemetti, M. M. (2024) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-024-01290-3 · Cited by 2
Gipson, E. Z., Deru, L. S., Graves, P. G., Jacobsen, C. G., Peterson, N. E., & Bailey, B. W. (2025) · Nutrition & Metabolism · doi:10.1186/s12986-025-00920-5 · Cited by 3
Houfková, A., Schmidt, M., Benek, O., Fabrik, I., Andrýs, R., Zemanová, L., Soukup, O., & Musílek, K. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01821-8 · Cited by 5
Age‐Dependent Metabolomic Signatures of Dietary Restriction in Mice
Lee, J., Arachchige, V. H. J. H., Kim, E., Bang, E., & Hong, Y. (2025) · Aging Cell · doi:10.1111/acel.70309 · Cited by 2
Wang, Y., Li, X., Huang, Z., Duan, A., Zhang, S., Wang, Q., Li, S., Gao, L., Zhao, Q., Yang, T., et al. (2025) · Clinical and Translational Science · doi:10.1111/cts.70426 · Cited by 2
Filippatos, T. D., Papadakis, J. A., Ioannou, P., Vrentzos, G. E., Theodorakopoulou, V., & Papanikolaou, K. (2022) · Current Hypertension Reviews · doi:10.2174/1573402118666220321121421 · Cited by 2
Liu, Q., Chen, X., Wei, S., & Wang, F. (2022) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-022-01126-8 · Cited by 3
Genetics and Epigenetics of Aging and Age-Associated Diseases
Naseer, A., & Nazir, A. (2023) · Springer eBooks · doi:10.1007/978-981-19-7443-4_1 · Cited by 2
Loveline, L. N., & Navti, L. K. (2024) · Journal of Diabetes and Endocrinology · doi:10.5897/jde2023.0155 · Cited by 2
Archana Gaur, T., Sakthivadivel, V., Taranikanti, M., John, N. A., Umesh, M., Ganji, V., & Medala, K. (2023) · INDIAN JOURNAL OF PHYSIOLOGY AND ALLIED SCIENCES · doi:10.55184/ijpas.v75i04.187 · Cited by 2
Peng, J., Huang, S., Wang, P., Luo, R., Zhang, W., Shi, X., Shi, L., Zhong, X., Lü, M., Peng, Y., et al. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003211 · Cited by 2
Assessment of cognitive disorders in elderly type 2 diabetic patients with obesity
Mohamed, A. H., Morsy, E. Y., Sorial, A. A. F., & Ramadan, A. M. (2024) · Alexandria Journal of Medicine · doi:10.1080/20905068.2024.2429302 · Cited by 3
Al‐Dwaikat, T. N., Al‐Samouri, H. K., Dalky, H. F., Hamaideh, S. H., ALBashtawy, M., & Khatatbeh, H. (2024) · Journal of Clinical Nursing · doi:10.1111/jocn.17606 · Cited by 2
Baye, A. M., Fenta, T. G., Karuranga, S., Nnakenyi, I. D., Young, E. E., Palmer, C., Pearson, E. R., Ulasi, I., & Dawed, A. Y. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1501383 · Cited by 2
Green Tea Mitigates the Hallmarks of Aging and Age-Related Multisystem Deterioration
Yilmaz, Y. N. (2013) · Aging and Disease · doi:10.14336/ad.2025.0398 · Cited by 3
Cnidoscolus Aconitifolius(Mill.) I.M. Johnst.: A Food Proposal Against Thromboembolic Diseases
Martínez, J. P. Q., & Campos, M. R. S. (2021) · Food Reviews International · doi:10.1080/87559129.2021.1934002 · Cited by 3
Cardiometabolic Profile Screening as an Early Detection of Cardiometabolic Risk
Sarastri, Y., Raynaldo, A. H., Ilyas, K. K., & Lubis, D. A. (2022) · Journal of Endocrinology Tropical Medicine and Infectiouse Disease (JETROMI) · doi:10.32734/jetromi.v4i2.9156 · Cited by 2
Bellissimo, N., Amalraj, R., Lee, J. J., Brett, N. R., de Zepetnek, J. O. T., Proteau, S., & Rousseau, D. (2020) · Nutrients · doi:10.3390/nu12092606 · Cited by 2
Physical Activity Correlates to Body Mass Index among Medical Students
Vikawati, N. E., Sarosa, H., Makarim, F. R., & Fasitasari, M. (2020) · Jurnal Kedokteran Brawijaya · doi:10.21776/ub.jkb.2020.031.02.8 · Cited by 2
Minuzzi, L. G., da Conceição, L. R., Muñoz, V. R., Vieira, R. F. L., Gaspar, R. C., da Silva, A. S. R., Cintra, D. E., de Moura, L. P., Ropelle, E. R., Teixeira, A. M., et al. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155306 · Cited by 2
(2020) · Актуальные проблемы медицины · doi:10.18413/2687-0940-2020-43-1-54-64 · Cited by 2
Sharma, M., Jha, I. P., Chawla, S., Pandey, N., Chandra, O., Mishra, S. V., & Kumar, V. (2022) · Briefings in Bioinformatics · doi:10.1093/bib/bbac241 · Cited by 2
Швед, М. І., Yastremska, I. O., & Овсійчук, Р. М. (2023) · Здобутки клінічної і експериментальної медицини · doi:10.11603/1811-2471.2022.v.i4.13496 · Cited by 2
Karolczak, K., Guligowska, A., Sołtysik, B. K., Kostanek, J., Kostka, T., & Watała, C. W. (2024) · Nutrients · doi:10.3390/nu16030332 · Cited by 2
Badru, O. A., Alabi, T. A., & Enwerem, K. E. (2024) · Journal of Population and Social Studies · doi:10.25133/jpssv322024.027 · Cited by 2
Ratnasari, P. M. D., Kurnianta, P. D. M., & Prasetya, A. A. N. P. R. (2020) · Majalah Farmasi dan Farmakologi · doi:10.20956/mff.v24i2.10384 · Cited by 2
Contribution of the Microbiota to Healthy Aging
Forssten, S. D., & Ouwehand, A. C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819265-8.00059-0 · Cited by 2
Chukwuma, C. (2022) · Mathews Journal of Diabetes & Obesity · doi:10.30654/mjdo.10014 · Cited by 2
Age-Related Changes in the Gut Microbiota Promote Atrial FibrillationPreprint
Zhang, Y., Zhang, S., Li, B., Luo, Y., Gong, Y., Jin, X., Zhang, J., Zhou, Y., Zhuo, X., Wang, Z., et al. (2020) · Research Square · doi:10.21203/rs.3.rs-51069/v1 · Cited by 2
Dynamic Risk Models for Characterising Chronic Diseases' Behaviour Using Process Mining Techniques
Valero-Ramón, Z. (2022) · doi:10.4995/thesis/10251/181652 · Cited by 2
Altered dynamics of ATP synthase cause functional irregularities in senescent hiPS-cardiomyocytesPreprint
Morris, S., Molina-Riquelme, I., Barrientos, G., Schmelter, F., Peischard, S., Seebohm, G., Eisner, V., & Busch, K. B. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.04.597306 · Cited by 2
Handayani, T., Darwinata, A. E., Wihandani, D. M., & Supadmanaba, I. G. P. (2021) · Indonesia Journal of Biomedical Science · doi:10.15562/ijbs.v15i2.333 · Cited by 1
Wang, Y., Hong, X., Cao, W. H., Lv, J., Yu, C., Huang, T., Sun, D., Liao, C., Pang, Y., Pang, Z., et al. (2023) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02164-7 · Cited by 1
Ageing-Related Alterations in Renal Epithelial Glucose Transport
Lee, C., Ng, H., Zhong, H.-R., Wang, Y., Liu, C.-H., & Lee, Y.-T. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216455 · Cited by 1
Li, M. H.-G., Boktor, R. R., Rowe, C. C., Weinberg, L., & Riedel, B. (2024) · Frontiers in Nuclear Medicine · doi:10.3389/fnume.2024.1412917 · Cited by 1
Ye, S., Fu, T., Tu, Y., Wellens, J., Chen, X., Larsson, S. C., Sun, J., Dan, L., Wang, X., Chen, J., et al. (2025) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjaf036 · Cited by 1
Metabolic dysfunction over a life course key to healthy ageing inequality
Littlewood, K., Gegic, J., Hickman, M., Henson, R. C. J., Bishop, J. R., Kershaw, T., Diamond, P., Slabaugh, G., Tranos, E., Vasilaki, A., et al. (2025) · Aging Clinical and Experimental Research · doi:10.1007/s40520-025-03034-3 · Cited by 2
Shrestha, R., Sapkota, S., & Briski, K. P. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin38142 · Cited by 1
Evans, M., Lewis, E. D., Joseph, A., Crowley, D., & Guthrie, N. (2025) · Journal of Food Science and Technology · doi:10.1007/s13197-025-06414-9 · Cited by 1
The protein phosphatase 6 subunit SAPS3 modulates lifespan by regulating metabolism
Yang, Y., Kang, D. E., Fan, Q., Hanse, E. A., Bae, H., Barahona, R. A., Shen, X., Ruiz, B. I., Lee, S., Pasterczyk, K. R., et al. (2025) · Science Advances · doi:10.1126/sciadv.adt3879 · Cited by 1
Abeywickrama, H. M., Koyama, Y., Uchiyama, M., & Okuda, A. (2025) · Healthcare · doi:10.3390/healthcare13212781 · Cited by 1
Brain Nutrient Sensing: A Unifying Framework
Blouet, C., & Schwartz, G. J. (2025) · Annual Review of Physiology · doi:10.1146/annurev-physiol-042324-100329 · Cited by 3
Glycemic status-dependent proteomic signatures of biological aging for health risk prediction
Li, J., Li, J., Xu, X., Yu, Y., Shen, W., Sun, Y., Fu, Y., Tan, X. W., Wang, N., Lu, Y., et al. (2025) · GeroScience · doi:10.1007/s11357-025-01950-w · Cited by 2
The effect of chronic hyperglycemia on aging: implications in cognitive impairment
Sarkar, A., Saha, S., & Bhattacharya, D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33355-2.00027-x · Cited by 1
Metadata
- Authors
- Chia, C. W., Egan, J. M., & Ferrucci, L.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Ferrucci, Luigi
- Venue
- Circulation Research
- Published
- 2018-09-14
- Volume
- 123
- Issue
- 7
- Pages
- 886-904
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC6205735
- OpenAlex
- W2891409258
- Semantic Scholar
- 5a8e379d2aa3e6281c5204edc4fa23822ef37775
- Cited by
- 454
- References
- 208
- Citations by year
- 2026: 61 · 2025: 71 · 2024: 72 · 2023: 82 · 2022: 70 · 2021: 38 · 2020: 42 · 2019: 15 · 2018: 1
- FWCI
- 3.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Aging (Z01AG000015)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- aging, glucose metabolism, hyperglycemia, cardiovascular risk, diabetes mellitus, older adults, obesity, insulin resistance, glycemic control, body composition, accelerated aging, cardiovascular disease
- MeSH terms
- Adipose Tissue, Age Factors, Aging, Animals, Blood Glucose, Cardiovascular Diseases, Health Status, Humans, Hyperglycemia, Insulin, Insulin Resistance, Models, Biological, Obesity, Prognosis, Risk Factors, Biomarkers, Prevalence, Risk Assessment, Adiposity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
