CoChat
Sign Up
Cited by 557Fatty Acid Research and HealthNutritional Studies and DietCardiovascular Health and Risk Factors

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Intake of Fish and n3 Fatty Acids and Risk of Coronary Heart Disease Among Japanese: The Japan Public Health Center-Based (JPHC) Study Cohort I

Iso, Hiroyasu, Kobayashi, Minatsu, Ishihara, Junko, Sasaki, Satoshi, Okada, Katsutoshi, Kita, Yoshikuni, Kokubo, Yoshihiro, Tsugane, Shoichiro·2006·Circulation
DOI 10.1161/circulationaha.105.581355
Open this paper in CoChat — free account

Abstract

BACKGROUND: Once- or twice-weekly consumption of fish (or a small amount of fish intake) reduces the risk of coronary heart disease and sudden cardiac death in Western countries. It is uncertain whether a high frequency or large amount of fish intake, as is the case in Japan, further reduces the risk. METHODS AND RESULTS: To examine an association between high intake of fish and n3 polyunsaturated fatty acids and the risk of coronary heart disease, a total of 41,578 Japanese men and women aged 40 to 59 years who were free of prior diagnosis of cardiovascular disease and cancer and who completed a food frequency questionnaire were followed up from 1990-1992 to 2001. After 477,325 person-years of follow-up, 258 incident cases of coronary heart disease (198 definite and 23 probable myocardial infarctions and 37 sudden cardiac deaths) were documented, comprising 196 nonfatal and 62 fatal coronary events. The multivariable hazard ratios (HRs) and 95% confidence intervals in the highest (8 times per week, or median intake=180 g/d) versus lowest (once a week, or median intake=23 g/d) quintiles of fish intake were 0.63 (0.38 to 1.04) for total coronary heart disease, 0.44 (0.24 to 0.81) for definite myocardial infarction, and 1.14 (0.36 to 3.63) for sudden cardiac death. The reduced risk was primarily observed for nonfatal coronary events (HR=0.43 [0.23 to 0.81]) but not for fatal coronary events (HR=1.08 [0.42 to 2.76]). Strong inverse associations existed between dietary intake of n3 fatty acids and risk of definite myocardial infarction (HR=0.35 [0.18 to 0.66]) and nonfatal coronary events (HR=0.33 [0.17 to 0.63]). CONCLUSIONS: Compared with a modest fish intake of once a week or &20 g/d, a higher intake was associated with substantially reduced risk of coronary heart disease, primarily nonfatal cardiac events, among middle-aged persons.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1161/circulationaha.105.581355

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 34 references

Research works printed but not linked: 4

  1. 10.1161/circ.104.19.2269 · DOI
  2. 10.1161/circ.102.22.2677 · DOI
  3. Ministry of Health Labour and Welfare. The National Nutrition Survey in Japan 2001. Health and Nutrition Information Research Committee eds. Tokyo Japan: Daiichi Shuppan; 2003: 83–91.
  4. 10.1161/circ.90.1.8026046 · DOI

Cited by

Sorted by citations

Items 401–500 of 557

Related

See all

Metadata

Authors
Iso, H., Kobayashi, M., Ishihara, J., Sasaki, S., Okada, K., Kita, Y., Kokubo, Y., & Tsugane, S.
Affiliations
University of Tsukuba (JP)
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2006-01-17
Volume
113
Issue
2
Pages
195-202
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/circulationaha.105.581355
OpenAlex
W2167934388
Cited by
557
References
34
Citations by year
2026: 7 · 2025: 4 · 2024: 13 · 2023: 16 · 2022: 18 · 2021: 19 · 2020: 26 · 2019: 21 · 2018: 23 · 2017: 33 · 2016: 21 · 2015: 26 · 2014: 32 · 2013: 48 · 2012: 37
FWCI
43.24
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Funders
University of Minnesota
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
fish consumption, omega-3 fatty acids, coronary artery disease, myocardial infarction, sudden cardiac death, dietary fat, Japanese population, middle-aged adults, cardiovascular risk
MeSH terms
Adult, Coronary Disease, Female, Fish Products, Follow-Up Studies, Food Preferences, Heart Diseases, Humans, Male, Middle Aged, Myocardial Infarction, Surveys and Questionnaires, Fatty Acids, Omega-3, Incidence, Odds Ratio, Death, Sudden, Cardiac

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review