Gaps in Public Knowledge of Peripheral Arterial Disease: The First National PAD Public Awareness Survey
Abstract
Background— Lower-extremity peripheral arterial disease (PAD) is associated with decreased functional status, diminished quality of life, amputation, myocardial infarction, stroke, and death. Nevertheless, public knowledge of PAD as a morbid and mortal disease has not been previously assessed. Methods and Results— We performed a cross-sectional, population-based telephone survey of a nationally representative sample of 2501 adults ≥50 years of age, with oversampling of blacks and Hispanics. The survey instrument measured the demographic, risk factor, and cardiovascular disease characteristics of the study population; prevalent leg symptoms; PAD awareness relative to atherosclerosis risk factors and other cardiovascular and noncardiovascular diseases; perceived causes of PAD; and perceived systemic and limb consequences of PAD. Respondents were 67.2±12.6 years of age with a high prevalence of risk factors but only a modest burden of known coronary or cerebrovascular disease. Twenty-six percent of respondents expressed familiarity with PAD, a rate significantly lower than that for any other cardiovascular disease or atherosclerosis risk factor. Within the “PAD-aware” cohort, knowledge was poor. Half of these individuals were not aware that diabetes and smoking increase the risk for PAD; 1 in 4 knew that PAD is associated with increased risk of heart attack and stroke; and only 14% were aware that PAD could lead to amputation. All knowledge domains were lower in individuals with lower income and education levels. Conclusions— The public is poorly informed about PAD, with major knowledge gaps regarding the definition of PAD, risk factors that lead to PAD, and associated limb symptoms and amputation risk. The public is not aware that PAD imposes a high short-term risk of heart attack, stroke, and death. For the national cardiovascular disease burden to be reduced, public PAD knowledge could be improved by national PAD public education programs designed to reduce critical knowledge gaps.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Awareness about PAD is low in the general population but especially among Black Americans.
“In addition, awareness about PAD is low in the general population but especially among Black Americans.”
From Racial and Ethnic Disparities in Peripheral Artery Disease (2021) · cites this paper as [45]
The Knowledge of Risk Factors section reports low PAD awareness—about 25%—and the Ethnicity, Socioeconomic Status, Gender, and Health Disparities section reports lower awareness among nonwhite respondents. The paper does not establish the claim specifically for Black Americans rather than nonwhite respondents as a group. Its survey also covered adults aged 50 or older, not the general population of all ages. (LLM, conf=0.83)
Experimental — accuracy not yet measuredIn a sample of 2501 adults over the age of 50 years, 15.2% of NHW and 12.1% of Hispanics knew that PAD can lead to amputation, whereas only 6.2% of Black Americans surveyed knew this.
“In a sample of 2501 adults over the age of 50 years, 15.2% of NHW and 12.1% of Hispanics knew that PAD can lead to amputation, whereas only 6.2% of Black Americans surveyed knew this.45”
From Racial and Ethnic Disparities in Peripheral Artery Disease (2021) · cites this paper as [45]
Table 5 (shown in the Predictors of PAD Awareness section; page unavailable) gives the stated amputation percentages for white, Hispanic, and Black respondents. But its heading specifies that these percentages are among respondents aware of PAD, not all 2501 adults surveyed. The Sample and Survey Design section also defines the sample as adults aged 50 or older, rather than over 50. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)
Norgren, L., Hiatt, W. R., Dormandy, J. A., Nehler, M. R., Harris, K. A., & Fowkes, F. G. R. (2007) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2006.12.037 · Cited by 8,191 · see citing works
Hirsch, A. T., Haskal, Z. J., Hertzer, N. R., Bakal, C. W., Creager, M. A., Halperin, J. L., Hiratzka, L. F., Murphy, W. R. C., Olin, J. W., Puschett, J. B., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.174526 · Cited by 3,708 · see citing works
Self-citation(2004) · PsycEXTRA Dataset · doi:10.1037/e442802008-001 · Cited by 2,882 · see citing works
Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care
Hirsch, A. T. (2001) · JAMA · doi:10.1001/jama.286.11.1317 · Cited by 2,835 · see citing works
Self-citationMortality over a Period of 10 Years in Patients with Peripheral Arterial Disease
Criqui, M. H., Langer, R. D., Fronek, A., Feigelson, H. S., Klauber, M. R., McCann, T. J., & Browner, D. (1992) · New England Journal of Medicine · doi:10.1056/nejm199202063260605 · Cited by 2,579 · see citing works
Self-citationSelvin, E., & Erlinger, T. P. (2004) · Circulation · doi:10.1161/01.cir.0000137913.26087.f0 · Cited by 1,885 · cited 1× · see citing works
“. .?”), ( 2 ) subject exposure to atherosclerosis risk factors (eg, “Do you have high blood pressure or are you Table 5. Perceived Consequences of PAD Among Those Aware of PAD by Demographic Characteristics in Response to the Question, “Based on What You Know or Have Heard, What Can PAD Lead to if Not Treated?””
BackgroundOne-year cardiovascular event rates in outpatients with atherothrombosis
Steg, P. G., Bhatt, D. L., Wilson, P. W. F., D’Agostino, R., Ohman, E. M., Röther, J., Liau, C.-S., Hirsch, A. T., Mas, J.-L., Ikeda, Y., et al. (2007) · JAMA · doi:10.1001/jama.297.11.1197 · Cited by 1,382 · see citing works
Self-citationBurt, V. L., Cutler, J. A., HIGGINS, M. W., Horan, M. J., Labarthe, D. R., Whelton, P. K., Brown, C., & Roccella, E. J. (1995) · Hypertension · doi:10.1161/01.hyp.26.1.60 · Cited by 1,252 · see citing works
State of disparities in cardiovascular health in the United States.
Mensah, G. A., Mokdad, A. H., Ford, E. S., Greenlund, K. J., & Croft, J. B. (2005) · Circulation · doi:10.1161/01.cir.0000158136.76824.04 · Cited by 1,213 · see citing works
Medical treatment of peripheral arterial disease and claudication
Hiatt, W. R. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105243442108 · Cited by 1,121 · see citing works
The prevalence of peripheral arterial disease in a defined population.
Criqui, M. H., Fronek, A. S., Barrett-Connor, E. L., Klauber, M. R., GABRIEL, S., & Goodman, D. (1985) · Circulation · doi:10.1161/01.cir.71.3.510 · Cited by 1,083 · see citing works
Self-citationEthnic-Specific Prevalence of Peripheral Arterial Disease in the United States
Allison, M. A., Ho, E., Denenberg, J. O., Langer, R. D., Newman, A. B., Fabsitz, R. R., & Criqui, M. H. (2007) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2006.12.010 · Cited by 574 · see citing works
Self-citationCritical Issues in Peripheral Arterial Disease Detection and Management A Call to Action
Belch, J. J. F. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.8.884 · Cited by 551 · see citing works
Racial Disparities in Hypertension Prevalence, Awareness, and Management
Hertz, R. P., Unger, A. N., Cornell, J. A., & Saunders, E. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.18.2098 · Cited by 528 · see citing works
Benefit of exercise conditioning for patients with peripheral arterial disease.
Hiatt, W. R., Regensteiner, J. G., Hargarten, M. E., Wolfel, E. E., & Brass, E. P. (1990) · Circulation · doi:10.1161/01.cir.81.2.602 · Cited by 501 · see citing works
Mosca, L. J. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.6.506 · Cited by 346 · see citing works
Racial and Geographic Differences in Awareness, Treatment, and Control of Hypertension
Howard, G., Prineas, R., Moy, C. S., Cushman, M., Kellum, M., Temple, E. M., Graham, A., & Howard, V. J. (2006) · Stroke · doi:10.1161/01.str.0000217222.09978.ce · Cited by 304 · see citing works
Summary health statistics for the U.S. population: National Health Interview Survey, 2007.
Adams, P. F., Barnes, P. M., & Vickerie, J. L. (2008) · PubMed · Cited by 238 · see citing works
Ferris, A., Robertson, R. M., Fabunmi, R. P., & Mosca, L. J. (2005) · Circulation · doi:10.1161/01.cir.0000157745.46344.a1 · Cited by 161 · see citing works
Self-citationAwareness, Knowledge, and Attitudes of Older Americans About High Blood Pressure
Egan, B. M., Lackland, D. T., & Cutler, N. E. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.6.681 · Cited by 149 · see citing works
Bias In List-Assisted Telephone Samples
Brick, J. M., Waksberg, J., Kulp, D., & Starer, A. (1995) · Public Opinion Quarterly · doi:10.1086/269470 · Cited by 137 · see citing works
McDermott, M. M., Mandapat, A. L., Moates, A., Albay, M., Chiou, E., Celic, L., & Greenland, P. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.18.2157 · Cited by 135 · see citing works
Muntner, P., DeSalvo, K. B., Wildman, R. P., Raggi, P., He, J., & Whelton, P. K. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj124 · Cited by 101 · see citing works
Hirsch, A. T., Halverson, S. L., Treat‐Jacobson, D., Hotvedt, P. S., Lunzer, M. M., Krook, S. H., Rajala, S., & Hunninghake, D. B. (2001) · Vascular Medicine · doi:10.1177/1358836x0100600204 · Cited by 101 · see citing works
Self-citationOnysko, J., Maxwell, C. J., Eliasziw, M., Zhang, J. X., Johansen, H., & Campbell, N. R. C. (2006) · Hypertension · doi:10.1161/01.hyp.0000242335.32890.c6 · Cited by 89 · see citing works
The Importance of Increasing Public and Physician Awareness of Peripheral Arterial Disease
Becker, G. J., McClenny, T. E., Kovacs, M. E., Raabe, R. D., & Katzen, B. T. (2002) · Journal of Vascular and Interventional Radiology · doi:10.1016/s1051-0443(07)60002-5 · Cited by 86 · see citing works
Wilson, R. P., Freeman, A., Kazda, M. J., Andrews, T. C., Berry, L. L., Vaeth, P. A. C., & Victor, R. G. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(01)01049-x · Cited by 84 · see citing works
Awareness and misconception of hypertension in Canada: results of a national survey.
Petrella, R. J., & Campbell, N. R. C. (2005) · PubMed · Cited by 56 · see citing works
Fraser, A. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl031 · Cited by 52 · see citing works
Ethnic Differences in Older Americans: Awareness, Knowledge, and Beliefs About Hypertension
Okonofua, E. C., Cutler, N. E., Lackland, D. T., & Egan, B. M. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.02.019 · Cited by 47 · see citing works
Hirsch, A. T., Gloviczki, P., Drooz, A. T., Lovell, M. B., & Creager, M. A. (2004) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2003.09.028 · Cited by 37 · see citing works
Self-citationHypertension awareness and control in an inner-city African–American sample
Vn, P., Hyman, D. J., Vallbona, C., Toronjo, C. H., & Louis, K. (1997) · Journal of Human Hypertension · doi:10.1038/sj.jhh.1000445 · Cited by 34 · see citing works
Longstreth, W. T. (2006) · Stroke · doi:10.1161/01.str.0000217259.92964.62 · Cited by 15 · see citing works
Ismail, H. M., Jackson, K., & Smith, D. C. (2006) · Journal of Investigative Medicine · doi:10.2310/6650.2006.05049 · Cited by 8 · see citing works
Flagged first, then by citations
1 of the 37 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [17]17. NHLBI Workshop on Peripheral Arterial Disease (PAD): Developing a Public Awareness Campaign Meeting Summary. Bethesda, Md: US Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute; 2003.
Cited by
Sorted by citations
Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association
Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R., de Ferranti, S. D., Floyd, J., Fornage, M., Gillespie, C., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000485 · Cited by 12,591 · see citing works
Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Delling, F. N., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000757 · Cited by 9,175 · see citing works
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300 · see citing works
Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association
Writing Group Members, Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31823ac046 · Cited by 7,333 · see citing works
Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., Das, S. R., de Ferranti, S., Després, J.-P., Fullerton, H. J., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000350 · Cited by 6,596 · see citing works
Self-citationHeart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Adams, R. J., Berry, J. D., Brown, T. M., Carnethon, M. R., Dai, S., de Simone, G., Ford, E. S., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182009701 · Cited by 6,149 · see citing works
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Alonso, A., Beaton, A. Z., Bittencourt, M. S., Boehme, A. K., Buxton, A. E., Carson, A. P., Commodore-Mensah, Y., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001052 · Cited by 5,987 · see citing works
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797 · see citing works
Self-citationHeart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000950 · Cited by 5,784 · see citing works
Heart Disease and Stroke Statistics—2010 Update: A Report From the American Heart Association
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R. J., Brown, T. M., Carnethon, M., Dai, S., De Simone, G., Ferguson, T. B., Ford, E., Furie, K., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192667 · Cited by 5,700 · see citing works
Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31828124ad · Cited by 5,292 · see citing works
Self-citationHeart Disease and Stroke Statistics—2014 Update
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Blaha, M. J., Dai, S., Ford, E. S., Fox, C. S., Franco, S., et al. (2013) · Circulation · doi:10.1161/01.cir.0000441139.02102.80 · Cited by 5,207 · see citing works
Self-citationHeart Disease and Stroke Statistics—2009 Update
WRITING GROUP MEMBERS, Lloyd‐Jones, D. M., Adams, R. J., Carnethon, M. R., SIMONE, G. D., Ferguson, T. B., Flegal, K. M., Ford, E. S., Furie, K. L., Go, A. S., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191259 · Cited by 3,891 · see citing works
Heart Disease and Stroke Statistics—2008 Update
Writing Group Members, Rosamond, W. D., Flegal, K. M., Furie, K. L., Go, A. S., Greenlund, K. J., Haase, N., Hailpern, S. M., Ho, M., Howard, V. J., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.187998 · Cited by 3,745 · see citing works
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191261 · Cited by 3,140 · see citing works
Martin, S. S., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Barone Gibbs, B., Beaton, A. Z., Boehme, A. K., et al. (2024) · Circulation · doi:10.1161/cir.0000000000001209 · Cited by 2,800 · see citing works
The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030
Vogel, B., Mónica Acevedo, B., Appelman, Y., Merz, C. N. B., Chieffo, A., Figtree, G. A., Guerrero, M. E., Kunadian, V., Lam, C. S. P., Maas, A. H. E. M., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00684-x · Cited by 1,536 · see citing works
Song, P., Rudan, D., Zhu, Y., Fowkes, F. J. I., Rahimi, K., Fowkes, F. G. R., & Rudan, I. (2019) · The Lancet Global Health · doi:10.1016/s2214-109x(19)30255-4 · Cited by 1,338 · see citing works
Martin, S. S., Aday, A. W., Allen, N. B., Almarzooq, Z., Anderson, C. A. M., Arora, P. K., Avery, C. L., Baker-Smith, C. M., Bansal, N., Beaton, A., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001303 · Cited by 1,206 · see citing works
A Call to Action: Women and Peripheral Artery Disease
Hirsch, A. T., Allison, M., Gomes, A. S., Corriere, M. A., Duval, S., Ershow, A. G., Hiatt, W. R., Karas, R. H., Lovell, M. B., McDermott, M. M., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31824c39ba · Cited by 351 · see citing works
Self-citationAssociation of Statin Dose With Amputation and Survival in Patients With Peripheral Artery Disease
Arya, S., Khakharia, A., Binney, Z. O., DeMartino, R. R., Brewster, L. P., Goodney, P. P., & Wilson, P. W. F. (2018) · Circulation · doi:10.1161/circulationaha.117.032361 · Cited by 257 · see citing works
ESVM Guideline on peripheral arterial disease
Frank, U., Nikol, S., Belch, J. J. F., Boc, V., Brodmann, M., Carpentier, P., Chraim, A., Canning, C., Dimakakos, E. P., Gottsäter, A., et al. (2019) · VASA · doi:10.1024/0301-1526/a000834 · Cited by 251 · see citing works
Armstrong, E. J., Chen, D. C., Westin, G. G., Singh, S., McCoach, C. E., Bang, H., Yeo, K. K., Anderson, D. R., Amsterdam, E. A., & Laird, J. R. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.113.000697 · Cited by 247 · see citing works
Prior polyvascular disease: risk factor for adverse ischaemic outcomes in acute coronary syndromes
Bhatt, D. L., Peterson, E. D., Harrington, R. A., Ou, F., Cannon, C. P., Gibson, C. M., Kleiman, N. S., Brindis, R. G., Peacock, W. F., Brener, S., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp099 · Cited by 201 · see citing works
Creager, M. A., Matsushita, K., Arya, S., Beckman, J. A., Duval, S., Goodney, P. P., Gutierrez, J. A. T., Kaufman, J. A., Joynt Maddox, K. E., Pollak, A. W., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000967 · Cited by 164 · see citing works
Self-citationGoodney, P. P., Tarulli, M., Faerber, A. E., Schanzer, A., & Zwolak, R. M. (2014) · JAMA Surgery · doi:10.1001/jamasurg.2014.1007 · Cited by 145 · see citing works
Racial and Ethnic Disparities in Peripheral Artery Disease
Hackler, E. L., Hamburg, N. M., & White Solaru, K. T. (2021) · Circulation Research · doi:10.1161/circresaha.121.318243 · Cited by 141 · see citing works
Subherwal, S., Patel, M. R., Kober, L., Peterson, E. D., Bhatt, D. L., Gislason, G. H., Olsen, A.-M. S., Jones, W. S., Torp-Pedersen, C., & Fosbol, E. L. (2015) · European Journal of Preventive Cardiology · doi:10.1177/2047487313519344 · Cited by 129 · see citing works
An international survey: Public awareness and perception of sepsis*
Rubulotta, F. M., Ramsay, G., Parker, M. M., Dellinger, R. P., Levy, M. M., & Poeze, M. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181926883 · Cited by 118 · see citing works
Epidemiology of Peripheral Artery Disease: Narrative Review
Horváth, L., Németh, N., Fehér, G., Kívés, Z., Endrei, D., & Boncz, I. (2022) · Life · doi:10.3390/life12071041 · Cited by 108 · see citing works
Biomarkers of Peripheral Arterial Disease
Cooke, J. P., & Wilson, A. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.08.090 · Cited by 109 · see citing works
Peripheral arterial disease: Lack of awareness in Canada
Lovell, M. B., Harris, K., Forbes, T. L., Twillman, G., Abramson, B. L., Criqui, M. H., Schroeder, P., Mohler, E. R., & Hirsch, A. T. (2009) · Canadian Journal of Cardiology · doi:10.1016/s0828-282x(09)70021-2 · Cited by 103 · see citing works
Self-citationLower extremity amputation in peripheral artery disease: improving patient outcomes
Jones, S., Swaminathan, A. C., Patel, M. R., & Vemulapalli, S. (2014) · Vascular Health and Risk Management · doi:10.2147/vhrm.s50588 · Cited by 102 · see citing works
Kalbaugh, C. A., Kucharska‐Newton, A., Wruck, L. M., Lund, J. L., Selvin, E., Matsushita, K., Bengtson, L. G. S., HEISS, G. M., & Loehr, L. R. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.116.003796 · Cited by 101 · see citing works
Hussain, M. A., Al-Omran, M. A., Mamdani, M., Eisenberg, N., Premji, A., Saldanha, L. S., Wang, X., Verma, S., & Lindsay, T. F. (2016) · JAMA Surgery · doi:10.1001/jamasurg.2016.0415 · Cited by 90 · see citing works
Endovascular Versus Open Revascularization for Peripheral Arterial Disease
Wiseman, J. T., Fernandes‐Taylor, S., Saha, S. A., Havlena, J. A., Rathouz, P. J., Smith, M. A., & Kent, K. C. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000001676 · Cited by 88 · see citing works
Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases
Levin, M. G., Klarin, D. M., Assimes, T. L., Freiberg, M. S., Ingelsson, E., Lynch, J. A., Natarajan, P., O’Donnell, C. J., Rader, D. J., Tsao, P. S., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.34461 · Cited by 85 · see citing works
Depression in patients with peripheral arterial disease: A systematic review
Brostow, D. P., Petrik, M. L., Starosta, A. J., & Waldo, S. W. (2017) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515116687222 · Cited by 81 · see citing works
Jaff, M. R., Cahill, K. E., Yu, A. P., Birnbaum, H. G., & Engelhart, L. (2010) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2010.03.015 · Cited by 78 · see citing works
Nonatherosclerotic Arterial Disorders of the Lower Extremities
Weinberg, I., & Jaff, M. R. (2012) · Circulation · doi:10.1161/circulationaha.111.060335 · Cited by 77 · see citing works
Song, P., Rudan, D., Wang, M., Chang, X., & Rudan, I. (2019) · Journal of Global Health · doi:10.7189/jogh.09.010601 · Cited by 76 · see citing works
Li, Z., Yang, Y., Wang, X., Yang, N., He, L., Wang, J., Ping, F., Xu, L., Zhang, H., Li, W., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03527-4 · Cited by 75 · see citing works
Abaraogu, U. O., Ezenwankwo, E. F., Dall, P., & Seenan, C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207456 · Cited by 71 · see citing works
Genetics of Peripheral Artery Disease
Leeper, N. J., Kullo, I. J., & Cooke, J. P. (2012) · Circulation · doi:10.1161/circulationaha.111.033878 · Cited by 70 · see citing works
Medication Underuse During Long-Term Follow-Up in Patients With Peripheral Arterial Disease
Hoeks, S. E., Reimer, W. J. M. S. O., van Gestel, Y. R. B. M., Schouten, O., Lenzen, M. J., Flu, W., van Kuijk, J., Latour, C. H. M., Bax, J. J., van Urk, H., et al. (2009) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.109.868505 · Cited by 69 · see citing works
Physiology in Medicine: Peripheral arterial disease
Muller, M. D., Reed, A. B., Leuenberger, U. A., & Sinoway, L. I. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00885.2013 · Cited by 69 · see citing works
Bridgwood, B. M., Nickinson, A., Houghton, J. S. M., Pepper, C., & Sayers, R. D. (2020) · Vascular Medicine · doi:10.1177/1358863x19893003 · Cited by 68 · see citing works
Polonsky, T. S., Taillon, L. A., Sheth, H., Min, J. K., Archer, S. L., & Ward, R. P. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.05.005 · Cited by 66 · see citing works
The role of nutrition and body composition in peripheral arterial disease
Brostow, D. P., Hirsch, A. T., Collins, T. C., & Kurzer, M. S. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.117 · Cited by 66 · see citing works
Self-citationInequalities in Scientific Understanding
Su, L. Y.-F., Cacciatore, M. A., Scheufele, D. A., Brossard, D., & Xenos, M. A. (2014) · Science Communication · doi:10.1177/1075547014529093 · Cited by 65 · see citing works
Disparities in Diagnosis, Treatment, and Outcomes of Peripheral Artery Disease
McDermott, M. M., Ho, K. J., Alabi, O., Criqui, M. H., Goodney, P. P., Hamburg, N. M., McNeal, D. M., Pollak, A. W., Smolderen, K. G. E., & Bonaca, M. P. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.09.830 · Cited by 65 · see citing works
Self-citationWang, Z., Wang, X., Hao, G., Chen, Z., Zhang, L., Shao, L., Tian, Y., Dong, Y., Zheng, C., Kang, Y., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.10.047 · Cited by 60 · see citing works
Gray, W. A., Garcia, L. A., Amin, A., & Shammas, N. W. (2017) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2017.12.015 · Cited by 55 · see citing works
Challenges associated with peripheral arterial disease in women
Barochiner, J., Aparicio, L. S., & Waisman, G. D. (2014) · Vascular Health and Risk Management · doi:10.2147/vhrm.s45181 · Cited by 53 · see citing works
Peripheral Arterial Disease in Women: The Gender Effect
Patel, T., Baydoun, H., Patel, N. K., Tripathi, B., Nanavaty, S. P., Savani, S., Mojadidi, M. K., Agarwal, N., Patel, G., Patel, S., et al. (2019) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2019.05.026 · Cited by 53 · see citing works
Peripheral Arterial Disease Associated With Caries and Periodontal Disease
Soto‐Barreras, U., Olvera‐Rubio, J. O., Loyola-Rodríguez, J. P., Reyes-Macias, J. F., Martínez-Martínez, R. E., Patiño‐Marín, N., Martínez-Castañón, G. A., Aradillas-García, C., & Little, J. W. (2012) · Journal of Periodontology · doi:10.1902/jop.2012.120051 · Cited by 52 · see citing works
Meadows, T. A., Bhatt, D. L., Hirsch, A. T., Creager, M. A., Califf, R. M., Ohman, E. M., Cannon, C. P., Eagle, K. A., Alberts, M. J., Goto, S., et al. (2009) · American Heart Journal · doi:10.1016/j.ahj.2009.09.014 · Cited by 50 · see citing works
Self-citationPeripheral arterial disease: A growing problem for the internist
Stehouwer, C. D. A., Clement, D. L., Davidson, C., Diehm, C., Elte, J. W. F., Lambert, M., & Séréni, D. (2008) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2008.09.013 · Cited by 50 · see citing works
RetractedNorgren, L., Hiatt, W. R., Dormandy, J., Hirsch, A. T., Jaff, M. R., Diehm, C., Baumgärtner, I., & Belch, J. J. F. (2010) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2010.05.005 · Cited by 49 · see citing works
Self-citationA hidden problem: peripheral artery disease in women
Kavurma, M. M., Boccanfuso, L. M., Cutmore, C., Passam, F. H., Patel, S., Hennessy, A., Loa, J., Figtree, G. A., Golledge, J., Robinson, D. A., et al. (2023) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcad011 · Cited by 47 · see citing works
Management of peripheral arterial disease patients: comparing the ACC/AHA and TASC-II guidelines
Mohler, E. R., & Giri, J. S. (2008) · Current Medical Research and Opinion · doi:10.1185/03007990802274379 · Cited by 48 · see citing works
Self-citationEvaluation of cuff-induced ischemia in the lower extremity by magnetic resonance oximetry
Langham, M. C., Floyd, T. F., Mohler, E. R., Magland, J. F., & Wehrli, F. W. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.08.068 · Cited by 46 · see citing works
Self-citationJeremias, A., Gruberg, L., Patel, J., Connors, G. W., & Brown, D. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.12.043 · Cited by 46 · see citing works
Sex Differences in Management and Outcomes of Critical Limb Ischemia in the Medicare Population
Mentias, A. G., Vaughan‐Sarrazin, M., Saad, M. S., & Girotra, S. R. (2020) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.120.009459 · Cited by 43 · see citing works
Robinson, W. P., Owens, C. D., Nguyen, L. L., Chong, T. T., Conte, M. S., & Belkin, M. (2009) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2009.02.010 · Cited by 43 · see citing works
Management of Peripheral Arterial Disease
Steffen, L. M., Duprez, D. A., Boucher, J. L., Ershow, A. G., & Hirsch, A. T. (2008) · Diabetes Spectrum · doi:10.2337/diaspect.21.3.171 · Cited by 42 · see citing works
Self-citationLiu, W., Yang, C., Chen, Z., Lei, F., Qin, J., Liu, H., Ji, Y., Zhang, P., Cai, J., Liu, Y.-M., et al. (2022) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2022.03.002 · Cited by 41 · see citing works
Prevalence of peripheral arterial disease in type 2 diabetics in Pakistan.
Akram, J., Aamir, A. H., Basit, A., Qureshi, M. S., Mehmood, T., Shahid, S. K., Khosa, I. A., Ebrahim, M. A., & Omair, A. A. (2011) · PubMed · Cited by 37 · see citing works
Peters, F., Kuchenbecker, J., Kreutzburg, T., Marschall, U., Debus, E. S., & Behrendt, C. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.018338 · Cited by 37 · see citing works
Global burden of atherosclerotic cardiovascular disease attributed to lifestyle and metabolic risks
Xu, S., Liu, Y., Zhu, M., Chen, K., Xu, F., & Liu, Y. (2025) · Science China Life Sciences · doi:10.1007/s11427-025-2948-y · Cited by 36 · see citing works
Kals, J., Zagura, M., Serg, M., Kampus, P., Zilmer, K., Unt, E., Lieberg, J., Eha, J., Peetsalu, A., & Zilmer, M. (2011) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2011.558108 · Cited by 36 · see citing works
Rafie, A. H. S., Stefanick, M. L., Sims, S. T., Phan, T., Higgins, M., Gabriel, A., Assimes, T. L., Narasimhan, B., Nead, K. T., MYERS, J. N., et al. (2010) · Vascular Medicine · doi:10.1177/1358863x10388345 · Cited by 36 · see citing works
Intermittent Claudication and Asymptomatic Peripheral Arterial Disease
Rümenapf, G., Morbach, S., Schmidt, A., & Sigl, M. (2020) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2020.0188 · Cited by 35 · see citing works
Girijala, R. L., & Bush, R. L. (2018) · Cureus · doi:10.7759/cureus.3418 · Cited by 33 · see citing works
Striberger, R., Axelsson, M., Zarrouk, M., & Kumlien, C. (2020) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2020.103723 · Cited by 34 · see citing works
Smolderen, K. G. E., Alabi, O., Collins, T. C., Dennis, B., Goodney, P. P., Mena‐Hurtado, C., Spertus, J. A., & Decker, C. (2022) · Circulation · doi:10.1161/cir.0000000000001105 · Cited by 33 · see citing works
Kolossváry, E., Farkas, K., Karahan, O., Golledge, J., Schernthaner, G.-H., Karplus, T. E., Bernardo, J. J., Marschang, S., Abola, M. T. B., Heinzmann, M., et al. (2023) · Vascular Medicine · doi:10.1177/1358863x231169316 · Cited by 32 · see citing works
Brunner, G., Yang, E. Y., Kumar, A., Sun, W., Virani, S. S., Negi, S., Murray, T. O., Lin, P. H., Hoogeveen, R. C., Chen, C., et al. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.09.034 · Cited by 30 · see citing works
Morikami, Y., Natsuaki, M., Morimoto, T., Ono, K., Nakagawa, Y., Furukawa, Y., Sakata, R., Aota, M., Okada, Y., Onoe, M., et al. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.04.005 · Cited by 30 · see citing works
n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial
Grenon, S. M., Owens, C. D., Alley, H. F., Chong, K. C., Yen, P. K., Harris, W. S., Hughes‐Fulford, M., & Conte, M. S. (2013) · Vascular Medicine · doi:10.1177/1358863x13503695 · Cited by 29 · see citing works
Identifying gaps in disease knowledge among patients with peripheral artery disease
Byskosh, N., Pamulapati, V., Xu, S., Vavra, A. K., Hoel, A. W., Tian, L., McDermott, M. M., Butt, Z. A., & Ho, K. J. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2021.11.036 · Cited by 28 · see citing works
Ho, V., Brown Johnson, C., Ghanzouri, I., Amal, S., Asch, S., & Ross, E. (2023) · JMIR Cardio · doi:10.2196/44732 · Cited by 28 · see citing works
Naicker, K., Liddy, C. E., Singh, J., Taljaard, M., & Hogg, W. E. (2014) · BMC Family Practice · doi:10.1186/1471-2296-15-123 · Cited by 28 · see citing works
Vaartjes, I. C. H., de Borst, G. J., Reitsma, J. B., de Bruin, A., Moll, F. L., Grobbee, D. E., & Bots, M. L. (2009) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-9-43 · Cited by 28 · see citing works
Statin use improves limb salvage after intervention for peripheral arterial disease
Parmar, G. M., Novak, Z., Spangler, E. L., Patterson, M. A., Passman, M. A., Beck, A. W., & Pearce, B. J. (2019) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.07.089 · Cited by 28 · see citing works
Polyunsaturated fatty acids and peripheral artery disease
Grenon, S. M., Hughes‐Fulford, M., Rapp, J. H., & Conte, M. S. (2012) · Vascular Medicine · doi:10.1177/1358863x11429175 · Cited by 27 · see citing works
Clinical and socioeconomic factors associated with unrecognized peripheral artery disease
Chang, P., Nead, K. T., Olin, J. W., Cooke, J. P., & Leeper, N. J. (2014) · Vascular Medicine · doi:10.1177/1358863x14535475 · Cited by 26 · see citing works
Treatment of Infrapopliteal Critical Limb Ischemia in 2013: The Wound Perfusion Approach
Bunte, M. C., & Shishehbor, M. H. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0363-5 · Cited by 25 · see citing works
the PANDORA Study Investigators, Cimminiello, C., Borghi, C., Kownator, S., Wautrecht, J.-C., Carvounis, C. P., Kranendonk, S. E., Kindler, B., & Mangrella, M. (2010) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-10-35 · Cited by 25 · see citing works
Peripheral artery disease, biomarkers, and darapladib
Berger, J. S., Ballantyne, C. M., Davidson, M. H., Johnson, J. L., Tarka, E. A., Lawrence, D., Trivedi, T., Zalewski, A. A., & Mohler, E. R. (2011) · American Heart Journal · doi:10.1016/j.ahj.2011.01.017 · Cited by 25 · see citing works
Self-citationHibi, K., Kimura, T., Kimura, K., Morimoto, T., Hiro, T., Miyauchi, K., Nakagawa, Y., Yamagishi, M., Ozaki, Y., Saito, S., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.08.024 · Cited by 25 · see citing works
Peripheral Artery Disease: A Marked Lack of Awareness in Ireland
Cronin, C. T., McCartan, D. P., McMonagle, M. P., Cross, K. S., & Dowdall, J. F. (2015) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2014.12.017 · Cited by 24 · see citing works
Ahn, S., Park, Y., Min, S., Kim, S. Y., Ha, J., Kim, S. J., Kim, H.-S., Yoon, B., & Min, S. (2012) · Journal of Korean Medical Science · doi:10.3346/jkms.2012.27.6.625 · Cited by 24 · see citing works
Kim, C., Yang, Y. S., Ryu, G. W., & Choi, M. (2021) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvaa022 · Cited by 24 · see citing works
Risk Factor Treatment in Veteran Women at Risk for Cardiovascular Disease
Canter, D. L., Atkins, M. D., McNeal, C. J., & Bush, R. L. (2008) · Journal of Surgical Research · doi:10.1016/j.jss.2008.07.014 · Cited by 24 · see citing works
El Morr, C., AlHamzah, M., Ng, P., Purewal, A., & Al-Omran, M. (2017) · Vascular · doi:10.1177/1708538116689355 · Cited by 23 · see citing works
Sex and Racial Disparities in Peripheral Artery Disease
Divakaran, S., Krawisz, A. K., Secemsky, E. A., & Kant, S. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319399 · Cited by 23 · see citing works
Jeevanantham, V., Chehab, B., Austria, É., Shrivastava, R. K., Wiley, M. A., Tadros, P., Dawn, B., Vacek, J. L., & Gupta, K. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.07.023 · Cited by 22 · see citing works
Peripheral artery disease patients are poorly aware of their disease
Builytė, I. U., Baltrūnas, T., Butkutė, E., Srinanthalogen, R., Skrebūnas, A., Urbonavičius, S., & Ručinskas, K. (2019) · Scandinavian Cardiovascular Journal · doi:10.1080/14017431.2019.1645350 · Cited by 22 · see citing works
Lifetime risk of lower extremity peripheral arterial disease: a Danish nationwide longitudinal study
Søgaard, M., Behrendt, C., Eldrup, N., & Skjøth, F. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae867 · Cited by 20 · see citing works
- Authors
- Hirsch, A. T., Murphy, T. P., Lovell, M. B., Twillman, G., Treat-Jacobson, D., Harwood, E. M., Mohler, E. R., Creager, M. A., Hobson, R. W., Robertson, R. M., Howard, W. J., Schroeder, P., & Criqui, M. H.
- Affiliations
- University of Minnesota (US)
- From the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (A.T.H., E.M.H.); Minneapolis Heart Institute Foundation, Minneapolis, Minn (A.T.H.); Rhode Island Hospital and Lifespan, Inc, Providence (T.P.M.); Division of Vascular Surgery, London Health Sciences Center, London, Ontario, Canada (M.B.L.); Peripheral Arterial Disease Coalition, Washington, DC (G.T.); University of Minnesota School of Nursing, Minneapolis (D.T.-J.); University of...
- Corresponding author
- Hirsch, Alan T.
- Venue
- Circulation
- Published
- 2007-10-30
- Volume
- 116
- Issue
- 18
- Pages
- 2086-2094
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2120827920
- Semantic Scholar
- 4d0f333b1d5b9eda793adabe9d5315707a7b95fa
- Cited by
- 273
- References
- 37
- Citations by year
- 2026: 10 · 2025: 12 · 2024: 16 · 2023: 22 · 2022: 17 · 2021: 17 · 2020: 14 · 2019: 14 · 2018: 10 · 2017: 8 · 2016: 18 · 2015: 6 · 2014: 13 · 2013: 13 · 2012: 18
- FWCI
- 16.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bristol-Myers Squibb
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Boston Scientific Corporation
- Otsuka America
- National Institutes of Health
- Abbott Vascular
- National Heart, Lung, and Blood Institute
- Topics
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
- Keywords
- peripheral arterial disease, public awareness, health knowledge gaps, atherosclerosis risk factors, diabetes mellitus, smoking, amputation risk, stroke risk, myocardial infarction risk, lower extremity symptoms, socioeconomic disparities, health education
- MeSH terms
- Adult, Aged, Aged, 80 and over, Awareness, Cross-Sectional Studies, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Risk Factors, United States, Peripheral Vascular Diseases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
