The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.
Cocoa and Cardiovascular Health
Open accessAbstract
Epidemiological data demonstrate that regular dietary intake of plant-derived foods and beverages reduces the risk of coronary heart disease and stroke. Among many ingredients, cocoa might be an important mediator. Indeed, recent research demonstrates a beneficial effect of cocoa on blood pressure, insulin resistance, and vascular and platelet function. Although still debated, a range of potential mechanisms through which cocoa might exert its benefits on cardiovascular health have been proposed, including activation of nitric oxide and antioxidant and antiinflammatory effects. This review summarizes the available data on the cardiovascular effects of cocoa, outlines potential mechanisms involved in the response to cocoa, and highlights the potential clinical implications associated with its consumption.
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“In laboratory studies and randomized trials, flavonoid-rich cocoa has small but measurable benefits on BP, endothelial function, insulin resistance, and blood lipids.295-297”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [296]
In the citing paper
“A few short-term trials of other dietary sources (e.g., tea, red wine, grapes) or specific flavonoid extracts have not consistently improved BP, lipid levels, or endothelial function.295-297”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [296]
In the citing paper
“In laboratory studies and randomized trials, flavonoid-rich cocoa has small but measurable benefits on BP, endothelial function, insulin resistance, and blood lipids.295-297”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [297]
In the citing paper
“A few short-term trials of other dietary sources (e.g., tea, red wine, grapes) or specific flavonoid extracts have not consistently improved BP, lipid levels, or endothelial function.295-297”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [297]
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“However, recent evidence from intervention trials have reported that intake of chocolate resulted in decreased blood pressure [2], increased high-density lipoprotein (HDL) cholesterol concentration [3], and improved insulin sensitivity [4], which have been suggested to be due to the antioxidant effects of flavonoids i…”
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“74 i upośledzoną tolerancją glukozy gorzka czekolada nie tylko obniżyła ciśnienie krwi i poprawiła funkcję śródbłonka, lecz także poprawiła wrażliwość na insulinę i funkcjonowanie komórek β89 [55].”
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“This is based on its ability to regulate at a low level the proinflammatory cytokines and their subsequent biochemical pathways (Corti et al., 2009). reduce the risk of diabetes (Katz et al., 2011).”
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DESENVOLVIMENTO E ACEITAÇÃO DE SORVETE DE ABACATE COM CACAU
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Polyphenols: The Pharmaceutical Approach and International Health
Suyal, K., Dhali, S., Ojha, A., & Pant, N. C. (2022) · Journal of Biomedical and Pharmaceutical Research · doi:10.32553/jbpr.v11i5.923
Metadata
- Authors
- Corti, R., Flammer, A. J., Hollenberg, N. K., & Lüscher, T. F.
- Affiliations
- Brigham and Women's Hospital (US)
- From the Cardiovascular Center, Cardiology University Hospital, Zurich, Switzerland (R.C., A.J.F., T.F.L.), and Department of Medicine and Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass (N.K.H.).
- Venue
- Circulation
- Published
- 2009-03-17
- Volume
- 119
- Issue
- 10
- Pages
- 1433-1441
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2105296434
- Cited by
- 424
- References
- 105
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 14 · 2023: 12 · 2022: 23 · 2021: 17 · 2020: 15 · 2019: 19 · 2018: 35 · 2017: 29 · 2016: 30 · 2015: 27 · 2014: 31 · 2013: 38 · 2012: 46
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.zora.uzh.ch
- Licence
- other-oa
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Chemistry and Fat Analysis
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- Theobroma cacao, cardiovascular health, coronary artery disease, stroke, blood pressure, insulin resistance, vascular function, platelet function, nitric oxide, antioxidant activity, anti-inflammatory activity, plant-based foods
- MeSH terms
- Adult, Aged, Antioxidants, Beverages, Cacao, Catechin, Endothelium, Vascular, Female, Flavonoids, Food Handling, Heart Diseases, Humans, Hyperlipidemias, Hypertension, Indians, Central American, Insulin Resistance, Iowa, Male, Phytotherapy, Medicine, Traditional, Middle Aged, Nitric Oxide, Platelet Aggregation, Switzerland, Overweight
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