What H.M. Taught us
Abstract
Studies on H.M. generated five main findings: that memory is a distinct psychological function, that amnesia spares short-term and working memory, that amnesia is an impairment of declarative and episodic memory, that the hippocampus is a core brain structure supporting memory, and that the hippocampus supports the permanent consolidation of memories. Each of these basic findings has recently been challenged, but a consideration of these studies suggests the new observations serve to support the original findings on H.M. and improve our understanding of the memory functions of the hippocampal system.
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The hippocampus is crucial to the establishment of episodic memory.
“Based on studies of patients with injury to the medial temporal lobe, it is well-accepted that the hippocampus is crucial to the establishment of episodic memory (Burgess et al., 2002; Eichenbaum, 2013; Squire and Zola-Morgan, 1991; Tulving and Markowitsch, 1998).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Eichenbaum, 2013
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Chao, O. Y., de Souza Silva, M. A., Yang, Y.-M., & Huston, J. P. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.04.007 · Cited by 158 · see citing works
- Authors
- Eichenbaum, H.
- Affiliations
- Boston University (US)
- Corresponding author
- Eichenbaum, Howard
- ORCID
- Eichenbaum, Howard
- Venue
- Journal of Cognitive Neuroscience
- Publisher
- MIT Press
- Published
- 2013-01-01
- Volume
- 25
- Issue
- 1
- Pages
- 14-21
- ISSN
- 0898-929X (ISSN-L)
- 1530-8898
- OpenAlex
- W2101166320
- Cited by
- 87
- References
- 73
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 6 · 2021: 8 · 2020: 7 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 5 · 2014: 10 · 2013: 10 · 2012: 1
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cognitive Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
- Keywords
- H&M, amnesia, declarative memory, episodic memory, short-term memory, working memory, hippocampus, memory consolidation, hippocampal system, memory function
- MeSH terms
- Amnesia, Animals, Hippocampus, Humans, Memory, Neuropsychology, History, 20th Century, History, 21st Century
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