Cited by 726Memory and Neural MechanismsMemory Processes and InfluencesNeurology and Historical Studies

What's new with the amnesic patient H.M.?

Corkin, Suzanne·2002·Nature Reviews Neuroscience

Abstract

H.M. became amnesic in 1953. Since that time, nearly 100 investigators, first at the Montreal Neurological Institute and since 1966 at the Massachusetts Institute of Technology, have participated in studying him. We all understand the rare opportunity we have had to work with him, and we are grateful for his dedication to research. He has taught us a great deal about the cognitive and neural organization of memory. We are in his debt.

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Crossref · 10.1038/nrn726

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7 of 7 references verified0 citation errors · 0 not checkable

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  • Integrity of hippocampal circuitry is a prerequisite for retaining an episode as well as spatial and temporal context information in memory for more than 15 min.

    “Integrity of hippocampal circuitry is a prerequisite for retaining an episode as well as spatial and temporal context information in memory for more than 15 min (231, 418).”

    From About Sleep's Role in Memory (2013) · cites this paper as [231]

  • The two-stage model has received strong support from lesion studies, indicating that lesions of the hippocampus abolish the ability to acquire new declarative memory and simultaneously produce a temporally graded retrograde amnesia where older memories remain intact.

    “For the declarative memory system, the two-stage model has received strong support from lesion studies, indicating that lesions of the hippocampus abolish the ability to acquire new declarative memory and simultaneously produce a temporally graded retrograde amnesia where older memories remain intact (231,418).”

    From About Sleep's Role in Memory (2013) · cites this paper as [231]

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Authors
Corkin, S.
Affiliations
Massachusetts Institute of Technology (US)
Corresponding author
Corkin, Suzanne
Venue
Nature Reviews Neuroscience
Published
2002-02
Volume
3
Issue
2
Pages
153-160
ISSN
  • 1471-003X (ISSN-L)
  • 1471-0048
OpenAlex
W1562191902
Cited by
726
References
7
Citations by year
2026: 15 · 2025: 23 · 2024: 32 · 2023: 22 · 2022: 33 · 2021: 24 · 2020: 31 · 2019: 92 · 2018: 21 · 2017: 50 · 2016: 29 · 2015: 28 · 2014: 32 · 2013: 42 · 2012: 41
FWCI
1.44
Type
journal article
Language
en
Open access
closed
Locations
  • Nature reviews. Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
Keywords
Henry Molaison, amnesia, memory systems, history of memory research
MeSH terms
Aged, Amnesia, Epilepsy, Temporal Lobe, Hippocampus, Humans, Longitudinal Studies, Male, Memory, Nerve Net, Neuropsychological Tests, Neurosurgical Procedures, Recovery of Function

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