Liver fibrosis

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323

The Versatile Role of microRNA-30a in Human Cancer

Wang, C., Yang, X., Chen, Y., & Chen, L. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000471111 · Cited by 3,414

Natural history of liver fibrosis progression in patients with chronic hepatitis C

Poynard, T., Bedossa, P., & Opolon, P. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07642-8 · Cited by 3,011

Nonalcoholic Steatohepatitis

Ludwig, J., Viggiano, T. R., McGill, D. B., & Ott, B. J. (1980) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(24)00530-5 · Cited by 2,903

J. Submicrosc. Cytol. Pathol.

Thomas, A. C., & Campbell, J. H. (2000) · Cited by 2,800

Epithelial-mesenchymal transition and its implications for fibrosis

Kalluri, R., & Neilson, E. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci20530 · Cited by 2,715

Epithelial-mesenchymal transition and its implications for fibrosis

Kalluri, R., & Neilson, E. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200320530 · Cited by 2,171

Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection

Regev, A., Berho, M. E., Jeffers, L. J., Milikowski, C., Molina, E. G., Pyrsopoulos, N., Feng, Z.-Z., Reddy, K. R., & Schiff, E. R. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.06038.x · Cited by 2,078

Hepatogastroenterology

Xu, D., He, X., Chang, Y., Sun, S., Xu, C., & Lin, J. (2012) · Hepatogastroenterology · doi:10.5754/hge12458 · Cited by 1,977

Liver fibrosis – from bench to bedside

Friedman, S. L. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00429-4 · Cited by 1,780

Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z

Sciacchitano, S., Lavra, L., Morgante, A., Ulivieri, A., Magi, F., Francesco, G. P. D., Bellotti, C., Salehi, L. B., & Rícci, A. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020379 · Cited by 387

Reversal of Hepatic Fibrosis — Fact or Fantasy?

Friedman, S. L., & Bansal, M. B. (2006) · Hepatology · doi:10.1002/hep.20974 · Cited by 380

The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases

Soares, J., Pimentel‐Nunes, P., Roncon‐Albuquerque, R., & Leite-Moreira, A. F. (2010) · Hepatology International · doi:10.1007/s12072-010-9219-x · Cited by 378

A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis

Fickert, P., Stöger, U., Fuchsbichler, A., Moustafa, T., Marschall, H., Weiglein, A. H., Tsybrovskyy, O., Jaeschke, H., Zatloukal, K., Denk, H., et al. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.061133 · Cited by 375

Non-invasive diagnosis of liver fibrosis and cirrhosis

Lurie, Y. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i41.11567 · Cited by 374

Hepatic stellate cells in physiology and pathology

Kamm, D. R., & McCommis, K. S. (2022) · The Journal of Physiology · doi:10.1113/jp281061 · Cited by 374

Liver Fibrosis: Noninvasive Assessment with MR Elastography versus Aspartate Aminotransferase–to-Platelet Ratio Index

Huwart, L., Sempoux, C. L., Salameh, N., Jamart, J., Annet, L., Sinkus, R., Peeters, F., ter Beek, L. C., Horsmans, Y., & BEERS, B. E. V. (2007) · Radiology · doi:10.1148/radiol.2452061673 · Cited by 371

Insulin resistance in hepatocytes and sinusoidal liver cells: Mechanisms and consequences

Leclercq, I. A., Morais, A. D. S., Schroyen, B., Hul, N. V., & Geerts, A. E. (2007) · Journal of Hepatology · doi:10.1016/j.jhep.2007.04.002 · Cited by 370

Experimental models of liver fibrosis

Yanguas, S. C., Cogliati, B., Willebrords, J., Maes, M., Colle, I. O., Bossche, B. V. D., de Oliveira, C. P. M. S., Andraus, W., Alves, V. A. F., Leclercq, I. A., et al. (2015) · Archives of Toxicology · doi:10.1007/s00204-015-1543-4 · Cited by 364

Beneficial effects of naringenin in liver diseases: Molecular mechanisms

Hernández‐Aquino, E., & Muriel, P. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i16.1679 · Cited by 358

Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis

Fabregat, I., & Caballero‐Díaz, D. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00357 · Cited by 359

Fibrosis and cancer: Do myofibroblasts come also from epithelial cells via EMT?

Radisky, D. C., Kenny, P. A., & Bissell, M. J. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21186 · Cited by 352

Role of immune cells in the removal of deleterious senescent cells

Kale, A., Sharma, A., Stolzing, A., Desprez, P.-Y., & Campisi, J. (2020) · Immunity & Ageing · doi:10.1186/s12979-020-00187-9 · Cited by 351

Myofibroblasts: Trust your heart and let fate decide

Davis, J., & Molkentin, J. D. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.10.019 · Cited by 347

The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma

Baglieri, J., Brenner, D. A., & Kisseleva, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071723 · Cited by 347

Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

Liedtke, C., Luedde, T., Sauerbruch, T., Scholten, D., Streetz, K. L., Tacke, F., Tolba, R. H., Trautwein, C., Trebicka, J., & Weiskirchen, R. (2013) · Fibrogenesis & Tissue Repair · doi:10.1186/1755-1536-6-19 · Cited by 346

The Immunology of Fibrosis

Wick, G., Grundtman, C., Mayerl, C., Wimpissinger, F., Feichtinger, J., Zelger, B. G., Sgonc, R., & Wolfram, D. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095937 · Cited by 347

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Omenetti, A., Porrello, A., Jung, Y., Yang, L., Popov, Y. V., Choi, S. S., Witek, R. P., Alpini, G. D., Venter, J., VanDongen, H. M. A., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci35875 · Cited by 346

Advances in the Diagnosis of Human Schistosomiasis

Weerakoon, K., Gobert, G. N., Cai, P., & McManus, D. P. (2015) · Clinical Microbiology Reviews · doi:10.1128/cmr.00137-14 · Cited by 341

Transforming growth factor-β and substrate stiffness regulate portal fibroblast activation in culture

Li, Z., Dranoff, J. A., Chan, E. P., Uemura, M., Sévigny, J., & Wells, R. G. (2007) · Hepatology · doi:10.1002/hep.21792 · Cited by 338

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

Aoyama, T., Paik, Y.-H., Watanabe, S., Laleu, B., Gaggini, F., Fioraso-Cartier, L., Molango, S., Heitz, F., Merlot, C., Szyndralewiez, C., et al. (2012) · Hepatology · doi:10.1002/hep.25938 · Cited by 336

Hepatocytes Do Not Undergo Epithelial-Mesenchymal Transition in Liver Fibrosis in Mice

Taura, K., Miura, K., Iwaisako, K., Österreicher, C. H., Kodama, Y., Penz-Österreicher, M., & Brenner, D. A. (2010) · Hepatology · doi:10.1002/hep.23368 · Cited by 336

Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease

Fouts, D. E., Torralba, M., Nelson, K. E., Brenner, D. A., & Schnabl, B. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.01.019 · Cited by 311

TGF ‐β as a driver of fibrosis: physiological roles and therapeutic opportunities

Budi, E. H., Schaub, J. R., Decaris, M. L., Turner, S., & Derynck, R. (2021) · The Journal of Pathology · doi:10.1002/path.5680 · Cited by 310

NF-κB signaling, liver disease and hepatoprotective agents

Sun, B., & Karin, M. (2008) · Oncogene · doi:10.1038/onc.2008.300 · Cited by 307

Septum Transversum-Derived Mesothelium Gives Rise to Hepatic Stellate Cells and Perivascular Mesenchymal Cells in Developing Mouse Liver §Δ

Asahina, K., Zhou, B., Pu, W. T., & Tsukamoto, H. (2010) · Hepatology · doi:10.1002/hep.24119 · Cited by 305

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

de Boer, Y. S., van Gerven, N. M. F., Zwiers, A., Verwer, B. J., van Hoek, B., van Erpecum, K. J., Beuers, U., van Buuren, H. R., Drenth, J. P. H., den Ouden, J. W., et al. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.04.022 · Cited by 304

Recent advancement of molecular mechanisms of liver fibrosis

Seki, E., & Brenner, D. A. (2015) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1002/jhbp.245 · Cited by 302

Non-Invasive markers for hepatic fibrosis

Baranova, A. V., Lal, P., Birerdinc, A., & Younossi, Z. M. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-91 · Cited by 299

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats #

Mejías, M., García‐Pras, E., Tiani, C., Miquel, R., Bosch, J., & Fernández, M. (2008) · Hepatology · doi:10.1002/hep.22758 · Cited by 299

Targeting Liver Fibrosis

Popov, Y. V., & Schuppan, D. (2009) · Hepatology · doi:10.1002/hep.23123 · Cited by 297

The role of TGF-β in the pathogenesis of primary open-angle glaucoma

Fuchshofer, R., & Tamm, E. R. (2011) · Cell and Tissue Research · doi:10.1007/s00441-011-1274-7 · Cited by 296

Mechanistic connection between inflammation and fibrosis

Lee, S. B., & Kalluri, R. (2010) · Kidney International · doi:10.1038/ki.2010.418 · Cited by 291

Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis

Kisseleva, T., & Brenner, D. A. (2007) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04658.x · Cited by 291

Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes

Deng, X., Zhang, X., Li, W., Feng, R.-X., Li, L., Yi, G.-R., Zhang, X.-N., Yin, C., Yu, H.-Y., Zhang, J.-P., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.05.022 · Cited by 289

Molecular Mechanisms Driving Progression of Liver Cirrhosis towards Hepatocellular Carcinoma in Chronic Hepatitis B and C Infections: A Review

Kanda, T., Goto, T., Hirotsu, Y., Moriyama, M., & Omata, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20061358 · Cited by 289

Liver fibrosis: Pathophysiology and clinical implications

Berumen, J. A., Baglieri, J., Kisseleva, T., & Mekeel, K. L. (2020) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1499 · Cited by 287

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models

Caddeo, S., Boffito, M., & Sartori, S. (2017) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2017.00040 · Cited by 285

Cytotherapy with M1-polarized macrophages ameliorates liver fibrosis by modulating immune microenvironment in mice

Ma, P.-F., Gao, C.-C., Yi, J., Zhao, J.-L., Liang, S.-Q., Zhao, Y., Ye, Y.-C., Bai, J., Zheng, Q.-J., Dou, K.-F., et al. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.05.022 · Cited by 284

Hepatic stellate cells and the reversal of fibrosis

Kisseleva, T., & Brenner, D. A. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04584.x · Cited by 283

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis

Inokuchi, S., Aoyama, T., Miura, K., Österreicher, C. H., Kodama, Y., Miyai, K. N., Akira, S., Brenner, D. A., & Seki, E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909781107 · Cited by 283

Role of the Inflammasome in Liver Disease

Ribeiro, M. D. C., & Szabó, G. (2021) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-032521-102529 · Cited by 286

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

Amann, T., Bataille, F., Spruß, T., Mühlbauer, M., Gäbele, E., Schölmerich, J., Kiefer, P., Bosserhoff, A., & Hellerbrand, C. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2009.01087.x · Cited by 282

Iron and liver fibrosis: Mechanistic and clinical aspects

Mehta, K. J., Farnaud, S., & Sharp, P. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i5.521 · Cited by 280

Cellular and Molecular Mechanisms Underlying Liver Fibrosis Regression

Caligiuri, A., Gentilini, A., Pastore, M., Gitto, S., & Marra, F. (2021) · Cells · doi:10.3390/cells10102759 · Cited by 283

Reversibility of liver fibrosis

Sun, M., & Kisseleva, T. (2015) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2015.06.015 · Cited by 280

STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity

Jeong, W., Park, O., Radaeva, S., & Gao, B. (2006) · Hepatology · doi:10.1002/hep.21419 · Cited by 279

Fibrosis Related Inflammatory Mediators: Role of the IL‐10 Cytokine Family

Sziksz, E., Pap, D., Lippai, R., Beres, N. J., Fekete, A., Szabo, A. J., & Vannay, Á. (2015) · Mediators of Inflammation · doi:10.1155/2015/764641 · Cited by 277

Lipid-based nanoparticle technologies for liver targeting

Böttger, R., Pauli, G., Chao, P., Fayez, N. A., Hohenwarter, L., & Li, S. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.017 · Cited by 277

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

Sicklick, J. K., Li, Y.-X., Jayaraman, A., Kannangai, R., Qi, Y. P., Vivekanandan, P., Ludlow, J. W., Owzar, K., Chen, W., Torbenson, M. S., et al. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi292 · Cited by 276

Transforming Growth Factor Beta Signaling in Hepatocytes Participates in Steatohepatitis Through Regulation of Cell Death and Lipid Metabolism in Mice

Yang, L., Roh, Y. S., Song, J., Zhang, B., Liu, C., Loomba, R., & Seki, E. (2014) · Hepatology · doi:10.1002/hep.26698 · Cited by 275

Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases

Gressner, O. A., & Gressner, A. M. (2008) · Liver International · doi:10.1111/j.1478-3231.2008.01826.x · Cited by 275

In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-α

Connolly, M. K., Bedrosian, A. S., Clair, J. M., Mitchell, A. P., Ibrahim, J., Stroud, A., Pachter, H. L., Bar‐Sagi, D., Frey, A. B., & Miller, G. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37581 · Cited by 272

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways

Wu, L., Zhang, Q., Mo, W., Feng, J., Li, S., Li, J., Liu, T., Xu, S., Wang, W., Lu, X., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-09673-5 · Cited by 271

Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C+ macrophage infiltration in mice

Baeck, C., Wei, X., Bartneck, M., Fech, V., Heymann, F., Gassler, N., Hittatiya, K., Eulberg, D., Luedde, T., Trautwein, C., et al. (2014) · Hepatology · doi:10.1002/hep.26783 · Cited by 270

Discovering Cell-Adhesion Peptides in Tissue Engineering: Beyond RGD

Huettner, N., Dargaville, T. R., & Forget, A. (2018) · Trends in biotechnology · doi:10.1016/j.tibtech.2018.01.008 · Cited by 270

Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target

Wang, H., Lafdil, F., Kong, X., & Gao, B. (2011) · International Journal of Biological Sciences · doi:10.7150/ijbs.7.536 · Cited by 270

Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis

Wehr, A., Baeck, C., Heymann, F., Niemietz, P. M., Hammerich, L., Martin, C., Zimmermann, H. W., Pack, O., Gassler, N., Hittatiya, K., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202909 · Cited by 268

Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

Berres, M., Koenen, R. R., Rueland, A., Zaldivar, M. M., Heinrichs, D., Sahin, H., Schmitz, P., Streetz, K. L., Berg, T., Gaßler, N., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41732 · Cited by 267

Platelet-derived serotonin links vascular disease and tissue fibrosis

Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Jüngel, A., Beyer, C., Krönke, G., Zwerina, J., et al. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20101629 · Cited by 266

Fructose Promotes Leaky Gut, Endotoxemia, and Liver Fibrosis Through Ethanol‐Inducible Cytochrome P450‐2E1–Mediated Oxidative and Nitrative Stress

Cho, Y., Kim, D., Seo, W., Gao, B., Yoo, S., & Song, B. (2019) · Hepatology · doi:10.1002/hep.30652 · Cited by 266

Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice

Yang, L., Kwon, J., Popov, Y. V., Gajdos, G. B., Ördög, T., Brekken, R. A., Mukhopadhyay, D., Schuppan, D., Bi, Y., Simonetto, D. A., et al. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.01.061 · Cited by 265

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

Karsdal, M. A., Manon‐Jensen, T., Genovese, F., Kristensen, J. H., Nielsen, M. J., Sand, J. M. B., Hansen, N. U. B., Bay‐Jensen, A., Bager, C. L., Krag, A. A., et al. (2015) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00447.2014 · Cited by 265

Hepatocellular Carcinoma: Etiology and Current and Future Drugs

Jindal, A., Thadi, A., & Shailubhai, K. (2019) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2019.01.004 · Cited by 264

Therapeutic strategies against TGF‐β signaling pathway in hepatic fibrosis

Liu, X., Hu, H., & Yin, J. Q. (2005) · Liver International · doi:10.1111/j.1478-3231.2005.01192.x · Cited by 263

Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts

Kim, K.-H., Chen, C.-C., Monzon, R. I., & Lau, L. F. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.00049-13 · Cited by 261

Hepatic triglyceride synthesis and nonalcoholic fatty liver disease

Choi, S. S., & Diehl, A. M. (2008) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3282ff5e55 · Cited by 261

Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice

Tipoe, G. L., Leung, T. M., Liong, E. C., Lau, T. Y. H., Fung, M., & Nanji, A. A. (2010) · Toxicology · doi:10.1016/j.tox.2010.04.014 · Cited by 261

miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1

Cardenas, C. L. L., Hénaoui, I. S., Courcot, E., Roderburg, C., Cauffiez, C., Aubert, S., Copin, M., Wallaert, B., Glowacki, F., Dewaeles, E., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003291 · Cited by 260

Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications

Alkhouri, N., Carter-Kent, C. A., & Feldstein, A. E. (2011) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.11.6 · Cited by 259

Microbiota, cirrhosis, and the emerging oral-gut-liver axis

Acharya, C., Sahingur, S. E., & Bajaj, J. S. (2017) · JCI Insight · doi:10.1172/jci.insight.94416 · Cited by 260

Exosome miR‐335 as a novel therapeutic strategy in hepatocellular carcinoma

Wang, F., Li, L., Piontek, K., Sakaguchi, M., & Selaru, F. M. (2018) · Hepatology · doi:10.1002/hep.29586 · Cited by 231

Cellular senescence controls fibrosis in wound healing

Jun, J.-I., & Lau, L. F. (2010) · Aging · doi:10.18632/aging.100201 · Cited by 255

Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease

Syn, W., Jung, Y., Omenetti, A., Abdelmalek, M. F., Guy, C. D., Yang, L., Wang, J., Witek, R. P., Fearing, C. M., Pereira, T. A., et al. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.06.051 · Cited by 257

Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

Hillebrandt, S., Wasmuth, H. E., Weiskirchen, R., Hellerbrand, C., Keppeler, H., Werth, A., Schirin-Sokhan, R., Wilkens, G., Geier, A., Lorenzen, J., et al. (2005) · Nature Genetics · doi:10.1038/ng1599 · Cited by 256

Review of MR elastography applications and recent developments

Glaser, K. J., Manduca, A., & Ehman, R. L. (2012) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.23597 · Cited by 255

Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics

Liaskou, E., Zimmermann, H. W., Li, K., Oo, Y. H., Suresh, S., Stamataki, Z., Qureshi, O. S., Lalor, P. F., Shaw, J., Syn, W., et al. (2012) · Hepatology · doi:10.1002/hep.26016 · Cited by 254

Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis

Ramachandran, P., Matchett, K. P., Dobie, R., Wilson-Kanamori, J. R., & Henderson, N. C. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-0304-x · Cited by 253

A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency

Burton, B. K., Balwani, M., Feillet, F., Barić, I., Burrow, T. A., Grande, C. C., Çöker, M., Consuelo‐Sánchez, A., Deegan, P. B., Rocco, M. D., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1501365 · Cited by 253

Cellular Mechanisms of Liver Fibrosis

Acharya, P., Chouhan, K., Weiskirchen, S., & Weiskirchen, R. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.671640 · Cited by 252

Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway

Shi, H., Dong, L., Jiang, J., Zhao, J., Zhao, G., Dang, X., Lu, X., & Jia, M. (2012) · Toxicology · doi:10.1016/j.tox.2012.10.025 · Cited by 251

Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review)

Katoh, M. (2018) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2018.3689 · Cited by 251

Abrogation of the Antifibrotic Effects of Natural Killer Cells/Interferon-γ Contributes to Alcohol Acceleration of Liver Fibrosis

Jeong, W., Park, O., & Gao, B. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.09.034 · Cited by 250

Fibrosis: ultimate and proximate causes

Thannickal, V. J., Zhou, Y., Gaggar, A., & Duncan, S. R. (2014) · Journal of Clinical Investigation · doi:10.1172/jci74368 · Cited by 249

Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches

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Hepatic fibrosis and cirrhosis: The (myo)fibroblastic cell subpopulations involved

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