The DOI matches its Crossref record; 114 of the 115 references it cites were found in a registry or an index.
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Open accessAbstract
Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and limiting MI size is timely and effective myocardial reperfusion using either thombolytic therapy or primary percutaneous coronary intervention (PPCI). However, the process of reperfusion can itself induce cardiomyocyte death, known as myocardial reperfusion injury, for which there is still no effective therapy. A number of new therapeutic strategies currently under investigation for preventing myocardial reperfusion injury have the potential to improve clinical outcomes in patients with acute MI treated with PPCI.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In cases such as myocardial IR, nano drug delivery vehicles accumulate in the injured tissue due to inflammation-mediated increased vascular permeability.160”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [160]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Yellon, D. M., & Hausenloy, D. J. (2007) · New England Journal of Medicine · doi:10.1056/nejmra071667 · Cited by 3,797
Self-citationZhao, Z., Corvera, J. S., Halkos, M. E., Kerendi, F., Wang, N.-P., Guyton, R. A., & Vinten‐Johansen, J. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01064.2002 · Cited by 2,073
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Stefani, D. D., Raffaello, A., Teardo, E., Szabó, I., & Rizzuto, R. (2011) · Nature · doi:10.1038/nature10230 · Cited by 1,957
Reimer, K. A., Lowe, J. E., Rasmussen, M. M., & Jennings, R. B. (1977) · Circulation · doi:10.1161/01.cir.56.5.786 · Cited by 1,944
Przyklenk, K., Bauer, B., Ovize, M., Kloner, R. A., & Whittaker, P. (1993) · Circulation · doi:10.1161/01.cir.87.3.893 · Cited by 1,379
Myocardial reperfusion: a double-edged sword?
D, E. B. M., & Kloner, R. A. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112160 · Cited by 1,368
Wu, K. C., Zerhouni, E. A., Judd, R. M., Lugo-Olivieri, C. H., Barouch, L. A., Schulman, S. P., Blumenthal, R. S., & Lima, J. A. C. (1998) · Circulation · doi:10.1161/01.cir.97.8.765 · Cited by 1,356
Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction
Piot, C. A., Croisille, P., Staat, P., Thibault, H., Rioufol, G., Mewton, N., Belghiti, R. E., Cung, T. T., Bonnefoy‐Cudraz, E., Angoulvant, D., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa071142 · Cited by 1,339
Direct measurement of free radical generation following reperfusion of ischemic myocardium.
Zweier, J. L., Flaherty, J. T., & Weisfeldt, M. L. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.5.1404 · Cited by 1,189
Ito, H., Tomooka, T., Sakai, N., Yu, H., Higashino, Y., Fujii, K., Masuyama, T., Kitabatake, A., & Minamino, T. (1992) · Circulation · doi:10.1161/01.cir.85.5.1699 · Cited by 1,052
Flagged first, then by citations
1 of the 115 references couldn’t be matched to a known paper.
Research works printed but not linked: 5
- Miyamae, 1996, Am J Physiol., 271, H2145
- Lemasters, 1996, EXS., 76, 99
- Atar, 2009, EFX., 53, 720
- Ytrehus, 1994, Am J Physiol., 267, H2383
- Duncker, 1996, Am J Physiol., 270, H1189
Cited by
Sorted by citations
Items 1,001–1,001 of 1,001
Dong, Q., Wang, Z., Wu, Q., & Du, Y. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118765 · Cited by 4
Metadata
- Authors
- Hausenloy, D. J., & Yellon, D. M.
- Affiliations
- University College London (GB)
- Corresponding author
- Yellon, Derek M.
- Venue
- Journal of Clinical Investigation
- Published
- 2013-01-02
- Volume
- 123
- Issue
- 1
- Pages
- 92-100
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC3533275
- OpenAlex
- W2051395985
- Cited by
- 2,357
- References
- 115
- Citations by year
- 2026: 176 · 2025: 177 · 2024: 226 · 2023: 218 · 2022: 236 · 2021: 231 · 2020: 240 · 2019: 226 · 2018: 172 · 2017: 124 · 2016: 130 · 2015: 101 · 2014: 69 · 2013: 28
- FWCI
- 16.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institute for Health and Care Research (NF-SI-0510-10164)
- British Heart Foundation (RG/03/007, RG/08/015/26411, FS/06/023)
- University College London
- Medical Research Council (MR/K002066/1)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Ischemia and Reperfusion
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- myocardial ischemia-reperfusion injury, acute myocardial infarction, cardiomyocyte death, primary percutaneous coronary intervention, thrombolysis, therapeutic target, cardioprotection
- MeSH terms
- Animals, Humans, Myocardial Infarction, Myocardial Reperfusion Injury, Thrombolytic Therapy, Cell Death, Myocytes, Cardiac, Percutaneous Coronary Intervention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
