Myocardial ischemia-reperfusion injury: a neglected therapeutic target

Myocardial Reperfusion Injury

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Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

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A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

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The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs.

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Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion.

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Myocardial reperfusion: a double-edged sword?

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Prognostic Significance of Microvascular Obstruction by Magnetic Resonance Imaging in Patients With Acute Myocardial Infarction

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Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

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Direct measurement of free radical generation following reperfusion of ischemic myocardium.

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Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction.

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From Brain to Heart: Possible Role of Amyloid-β in Ischemic Heart Disease and Ischemia-Reperfusion Injury

Gagno, G., Ferro, F., Fluca, A. L., Janjusevic, M., Rossi, M., Sinagra, G., Beltrami, A. P., Moretti, R., & Aleksova, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249655 · Cited by 36

Recent advances in potential of Fisetin in the management of myocardial ischemia-reperfusion injury–A systematic review

Prem, P. N., Sivakumar, B., Boovarahan, S. R., & Kurian, G. A. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154123 · Cited by 36

Emerging regulatory mechanisms in cardiovascular disease: Ferroptosis

Jin, S., Wang, H., Zhang, X., Song, M., Liu, B., & Sun, W. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116457 · Cited by 35

Restoration of autophagic flux in myocardial tissues is required for cardioprotection of sevoflurane postconditioning in rats

Zhang, Y., Yao, Y.-T., Fang, N., Zhou, C., Gong, J., & Li, L. (2014) · Acta Pharmacologica Sinica · doi:10.1038/aps.2014.20 · Cited by 35

Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size

Moon, S. H., Mancuso, D. J., Sims, H. F., Liu, X., Nguyen, A. L., Yang, K., Guan, S., Dilthey, B. G., Jenkins, C. M., Weinheimer, C. J., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.740597 · Cited by 37

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice

Witsch, T., Martinod, K., Sorvillo, N., Portier, I., Meyer, S. F. D., & Wagner, D. D. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.007004 · Cited by 35

Ligustrazine Exerts Cardioprotection in Animal Models of Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms

Zheng, Q., Huang, Y.-Y., Zhu, P.-C., Tong, Q., Bao, X., Zhang, Q., Zheng, G., & Wang, Y. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00729 · Cited by 35

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

Nagasaka, Y., Fernandez, B. O., Steinbicker, A. U., Spagnolli, E., Malhotra, R. K., Bloch, D. B., Bloch, K. D., Zapol, W. M., & Feelisch, M. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.08.006 · Cited by 35

Protective Effects ofGalium verum L.Extract against Cardiac Ischemia/Reperfusion Injury in Spontaneously Hypertensive Rats

Bradić, J., Zivkovic, V. I., Srejovic, I. M., Jakovljevic, V. L., Petković, A., Turnic, T. N., Jeremic, J. N., Jeremic, N. S., Mitrović, S., Šobot, T., et al. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/4235405 · Cited by 35

κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway

Wang, K., Liu, Z., Zhao, M., Zhang, F., Wang, K., Feng, N., Fu, F., Li, J., Li, J., Liu, Y., et al. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.172987 · Cited by 35

Computationally modeling mammalian succinate dehydrogenase kinetics identifies the origins and primary determinants of ROS production

Manhas, N., Duong, Q. V., Lee, P., Richardson, J. D., Robertson, J. D., Moxley, M. A., & Bazil, J. N. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.014483 · Cited by 36

Highly Efficient MicroRNA Delivery Using Functionalized Carbon Dots for Enhanced Conversion of Fibroblasts to Cardiomyocytes

Yang, L., Xue, S., Du, M., & Lian, F. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s304873 · Cited by 30

Liquiritin Protects Against Cardiac Fibrosis After Myocardial Infarction by Inhibiting CCL5 Expression and the NF-κB Signaling Pathway

Han, X., Yang, Y., Zhang, M., Li, L., Xue, Y., Jia, Q., Wang, X., & Guan, S. (2022) · Drug Design Development and Therapy · doi:10.2147/dddt.s386805 · Cited by 35

Glucagon-Like Peptide-1

Giblett, J. P., Clarke, S. J., Dutka, D. P., & Hoole, S. P. (2016) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2016.03.011 · Cited by 36

Cardioprotective effect of the xanthones from Gentianella acuta against myocardial ischemia/reperfusion injury in isolated rat heart

Wang, Z., Wu, G., Liu, H., Xing, N., Sun, Y., Zhai, Y., Yang, B., Kong, A. T., Kuang, H., & Wang, Q. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.06.068 · Cited by 35

Investigation of Cardioprotective Activity of Silybin: Network Pharmacology, Molecular Docking, and In Vivo Studies

Pasala, P. K., Donakonda, M., Prasanth, D., Rudrapal, M., Gouru, S. A., & Ruksana, K. (2023) · ChemistrySelect · doi:10.1002/slct.202300148 · Cited by 34

LDHA exacerbates myocardial ischemia-reperfusion injury through inducing NLRP3 lactylation

Li, F., Yu, Z., Qian, X., Fang, H., & Wang, Y. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-04251-w · Cited by 34

Pharmacological Mechanisms of Cryptotanshinone: Recent Advances in Cardiovascular, Cancer, and Neurological Disease Applications

Zheng, Z., Ke, L., Ye, S., Shi, P., & Yao, H. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s494555 · Cited by 34

Cardioprotective Effect of Electroacupuncture Pretreatment on Myocardial Ischemia/Reperfusion Injury via Antiapoptotic Signaling

Lu, S.-F., Huang, Y., Wang, N., Shen, W., Fu, S., Li, Q., Yu, M., Liu, W., Chen, X., Jing, X., et al. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/4609784 · Cited by 34

Junctophilin-2 is a target of matrix metalloproteinase-2 in myocardial ischemia–reperfusion injury

Chan, B. Y. H., Roczkowsky, A., Cho, W. J., Poirier, M., Lee, T. Y. T., Mahmud, Z., & Schulz, R. (2019) · Basic Research in Cardiology · doi:10.1007/s00395-019-0749-7 · Cited by 34

Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion

Penela, P., Inserte, J., Ramos, P. S., Rodríguez‐Sinovas, A., David Garcia-dorado, A., & Mayor, F. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.09.019 · Cited by 34

Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury

Xiang, Q., Wu, M., Zhang, L., Fu, W., Yang, J., Zhang, B., Zheng, Z., Zhang, H., Lao, Y., & Xu, H. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00452 · Cited by 34

Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion

Ren, D., He, Z., Fedorova, J., Zhang, J., Wood, E., Zhang, X., Kang, D. E., & Li, J. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101824 · Cited by 34

Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16

Zhao, G., Zhang, H., Zhu, S., Wang, S., Zhu, K., Zhao, Y., Xu, L., Zhang, P., Xie, J., Sun, A., et al. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110141 · Cited by 35

Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/reperfusion injury in mice

El-Awaisi, J., Kavanagh, D. P. J., Rink, M. R., Weston, C. J., Drury, N. E., & Kalia, N. (2022) · JCI Insight · doi:10.1172/jci.insight.155236 · Cited by 34

LncRNA Rian reduces cardiomyocyte pyroptosis and alleviates myocardial ischemia–reperfusion injury by regulating by the miR-17-5p/CCND1 axis

Kang, H. D., Yu, H., Zeng, L., Ma, H., & Cao, G. (2022) · Hypertension Research · doi:10.1038/s41440-022-00884-6 · Cited by 34

Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment‐Induced Cardioprotection against Ischemia‐Reperfusion Injury in Rats

Sun, H., Lu, Y., Wang, H., Zhang, H., Wang, S.-R., Xu, W., Fu, H.-L., Yao, X., Yang, F. H., & Yuan, H. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/2186383 · Cited by 34

C-Phycocyanin Ameliorates Mitochondrial Fission and Fusion Dynamics in Ischemic Cardiomyocyte Damage

Gao, J., Zhao, L., Wang, J., Zhang, L., Zhou, D., Qu, J., Wang, H., Yin, M., Hong, J., & Zhao, W. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00733 · Cited by 34

Interleukin 35 protects cardiomyocytes following ischemia/reperfusion-induced apoptosis via activation of mitochondrial STAT3

Zhou, F., Feng, T., Lu, X., Wang, H.-C., Chen, Y., Zhang, Q., Zhang, X., & Xiu, J. (2021) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmab007 · Cited by 33

Dynamin‐related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury

Piao, L. H., Fang, Y., Fisher, M. L., Hamanaka, R. B., Ousta, A., Wu, R., Mutlu, G. M., Garcia, A. J., Archer, S. L., & Sharp, W. W. (2023) · The FASEB Journal · doi:10.1096/fj.202301040rr · Cited by 35

Endoplasmic reticulum stress response in spontaneously hypertensive rats is affected by myocardial ischemia reperfusion injury

GUO, X.-F., & Yang, X. (2014) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2014.2094 · Cited by 33

Mitochondrial Membrane Permeability Inhibitors in Acute Myocardial Infarction

Trankle, C. R., Thurber, C. J., Toldo, S. A., & Abbate, A. (2016) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2016.06.012 · Cited by 33

Propofol attenuates myocardial ischemia reperfusion injury partly through inhibition of resident cardiac mast cell activation

Yu, X., Sun, X., Zhao, M. L., Hou, Y., Yu, J., Yu, J., & Hou, Y. (2017) · International Immunopharmacology · doi:10.1016/j.intimp.2017.11.015 · Cited by 33

Trichosanthis Pericarpium Aqueous Extract Protects H9c2 Cardiomyocytes from Hypoxia/Reoxygenation Injury by Regulating PI3K/Akt/NO Pathway

Chu, D., & Zhang, Z. (2018) · Molecules · doi:10.3390/molecules23102409 · Cited by 33

Inhibition of Smurf2 translation by miR-322/503 protects from ischemia-reperfusion injury by modulating EZH2/Akt/GSK3β signaling

Dong, W., Xie, F., Chen, X., Huang, W.-L., Zhang, Y., Luo, W.-B., Chen, J., Xie, M.-T., & Peng, X. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00375.2018 · Cited by 33

Ginkgo biloba Pretreatment Attenuates Myocardial Ischemia-Reperfusion Injury via mitoBK Ca

Li, T., Zhang, Y., Tian, J., Yang, L., & Wang, J. (2019) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x1950054x · Cited by 33

Molecular mechanisms underlying gallic acid effects against cardiovascular diseases: An update review.

Akbari, G. (2020) · PubMed Central · doi:10.22038/ajp.2019.13537 · Cited by 33

Hydrogen Sulfide Promotes Cardiomyocyte Proliferation and Heart Regeneration via ROS Scavenging

Pei, J., Wang, F., Pei, S., Bai, R., Cong, X., Nie, Y., & Chen, X. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/1412696 · Cited by 34

The Cardiac Lipidome in Models of Cardiovascular Disease

Tomczyk, M. M., & Dolinsky, V. W. (2020) · Metabolites · doi:10.3390/metabo10060254 · Cited by 33

Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis

Peng, K., Liu, H., Yan, B., Meng, X., Song, S., Ji, F., & Xia, Z. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29938 · Cited by 33

The gut microbial metabolite phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion through activating β2AR

Xu, X., Lu, W.-J., Shi, J., Su, Y.-L., Liu, Y.-C., Wang, L., Xiao, C.-X., Chen, C., & Lu, Q. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108720 · Cited by 33

Puerarin protects cardiomyocytes from ischemia–reperfusion injury by upregulating LncRNA ANRIL and inhibiting autophagy

Han, Y., Wang, H., Wang, Y., Dong, P., Jia, J., & Yang, S. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03463-2 · Cited by 33

Biomimetic PLGA Microbubbles Coated with Platelet Membranes for Early Detection of Myocardial Ischaemia-Reperfusion Injury

Xu, L., Chen, Y., Jin, Q., Wu, Y., Deng, C., Zhong, Y., Lin, L., Chen, L., Fu, W., Yi, L., et al. (2021) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.1c00145 · Cited by 33

Minimizing Ischemia Reperfusion Injury in Xenotransplantation

Patel, P. M., Connolly, M. R., Coe, T. M., Calhoun, A., Pollok, F., Markmann, J. F., Burdorf, L., Azimzadeh, A. M., Madsen, J. C., & Pierson, R. N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.681504 · Cited by 33

Treatment of myocardial ischaemia-reperfusion injury in patients with ST-segment elevation myocardial infarction: promise, disappointment, and hope

He, J., Bellenger, N. G., Ludman, A. J., Shore, A. C., & Strain, W. D. (2022) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2301023 · Cited by 33

Alpha-lipoic acid impedes myocardial ischemia-reperfusion injury, myocardial apoptosis, and oxidative stress by regulating HMGB1 expression

Qi, B., Zheng, Y., Gao, W., Qi, Z., Gong, Y., Liu, Y., Wang, Y., Cheng, X. W., Ning, M., Lang, Y., et al. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175295 · Cited by 33

The role of histone deacetylases in cardiac energy metabolism in heart diseases

Yu, Q., Zhao, G., Liu, J., Peng, Y., Xu, X., Zhao, F., Shi, Y., Jin, C., Zhang, J., & Wei, B. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155532 · Cited by 33

SIRT6 deficiency in endothelial cells exacerbates oxidative stress by enhancing HIF1α accumulation and H3K9 acetylation at the Ero1α promoter

Guo, Z., Yu, X., Zhao, S., Zhong, X., Huang, D., Feng, R., Li, P., Fang, Z., Hu, Y., Zhang, Z., et al. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1377 · Cited by 35

Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion-induced ferroptosis via the keap1/Nrf2/GPX4 signaling pathway

Zhong, G., Chen, J., Li, Y., Han, Y., Wang, M., Nie, Q., Xu, M., Zhu, Q., Chang, X., & Wang, L. (2024) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-024-04492-4 · Cited by 32

Neutrophil extracellular traps and cardiovascular disease: Associations and potential therapeutic approaches

Tang, Y., Jiao, Y., An, X., Tu, Q., & Jiang, Q. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117476 · Cited by 32

Crosstalk of autophagy and ferroptosis in cardiovascular diseases: from pathophysiology to novel therapy

Hu, C., Gao, S., Li, X., Yang, K., Cheng, Y., Guo, W., Wu, H., Cheng, X., Zhao, W., Kong, Y., et al. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103705 · Cited by 32

Mitochondrial dysfunction in H9c2 cells during ischemia and amelioration with Tribulus terrestris L.

Reshma, P. L., Sainu, N. S., Mathew, A. K., & Raghu, K. G. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.03.055 · Cited by 32

Protective roles of bioactive peptides during ischemia-reperfusion injury: From bench to bedside

Wu, D., Wang, J., Wang, H., Ji, A., & Li, Y. (2017) · Life Sciences · doi:10.1016/j.lfs.2017.05.014 · Cited by 32

Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury

Groehler, A. S., Kren, S. M., Li, Q., Robledo-Villafane, M., Schmidt, J., Garry, M. G., & Tretyakova, N. Y. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.03.010 · Cited by 32

Celastrol-type HSP90 modulators allow for potent cardioprotective effects

Aceros, H., Sarkissian, S. D., Borie, M., Stevens, L., Mansour, S., & Noiseux, N. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.04.025 · Cited by 32

Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats

Liu, X., Jiang, Y., Fu, W., Yu, X., & Sui, D. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4414 · Cited by 32

Regulation of metabolism by mitochondrial enzyme acetylation in cardiac ischemia-reperfusion injury

Herr, D. J., Singh, T. N., Dhammu, T. S., & Menick, D. R. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2020.165728 · Cited by 32

Role of nitroxyl (HNO) in cardiovascular system: From biochemistry to pharmacology

Sun, H., Wu, Z., Cao, L., Zhu, M., Nie, X.-W., Huang, D., Sun, M., & Bian, J. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104961 · Cited by 32

Preclinical rodent models of cardiac fibrosis

Wang, Y., Wang, M., Samuel, C. S., & Widdop, R. E. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15450 · Cited by 33

Transcriptomic Hallmarks of Ischemia-Reperfusion Injury

Movahed, M., Brockie, S. T., Hong, J., & Fehlings, M. G. (2021) · Cells · doi:10.3390/cells10071838 · Cited by 33

miR-190-5p Alleviates Myocardial Ischemia-Reperfusion Injury by Targeting PHLPP1

Li, Y., Li, Z., Liu, J., Liu, Y., & Miao, G. (2021) · Disease Markers · doi:10.1155/2021/8709298 · Cited by 32

Propofol protects cardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling pathways

Lu, Z., Liu, Z., & Fang, B. (2022) · Bioengineered · doi:10.1080/21655979.2022.2036895 · Cited by 32

Indole-3-Carbinol (I3C) Protects the Heart From Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Cellular Apoptosis in Mice

Li, Q., Xia, B., Wu, J., Yuan, X., Xu, L., Huang, C., Gu, H., Zheng, K., You, Q., & Liu, K. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.924174 · Cited by 32

Mammalian Target of Rapamycin Inhibition in Patients With ST-Segment Elevation Myocardial Infarction

Stähli, B. E., Klingenberg, R., Heg, D., Branca, M., Manka, R., Kapos, I., Müggler, O., Denegri, A., Kesterke, R., Berger, F., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.08.747 · Cited by 32

Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction

Kraan, T. C. T. M. V. D. P., Bernink, F. J. P., Yıldırım, C., Koolwijk, P., Baggen, J. M. C., Timmers, L., Beek, A. M., Diamant, M., Chen, W. J. Y., van Rossum, A. C., et al. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.12.021 · Cited by 32

Alternative Interventions to Prevent Oxidative Damage following Ischemia/Reperfusion

Rodríguez-Lara, S. Q., Cardona-Muñóz, E. G., Ramírez-Lizardo, E. J., Totsuka-Sutto, S. E., Castillo‐Romero, A., García-Cobián, T. A., & García‐Benavides, L. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/7190943 · Cited by 32

2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice

Morihara, H., Obana, M., Tanaka, S., Kawakatsu, I., Tsuchiyama, D., Mori, S., Suizu, H., Ishida, A., Kimura, R., Tsuchimochi, I., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0189948 · Cited by 32

Curcumin attenuates hypoxia/reoxygenation‑induced cardiomyocyte injury by downregulating Notch signaling

Zhu, P., Yang, M., He, H., Kuang, Z., Liang, M., Lin, A., Song, L., Wen, Q., Cheng, Z., & Sun, C. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10371 · Cited by 32

Poly (ADP‐ribose) polymerase inhibition protects against myocardial ischaemia/reperfusion injury via suppressing mitophagy

Cao, S., Sun, Y., Wang, W., Wang, B., Zhang, Q., Pan, C., Yuan, Q., Xu, F., Wei, S., & Chen, Y. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14573 · Cited by 33

MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis

Liu, H., Li, S., Jiang, W., & Li, Y. (2019) · Korean Circulation Journal · doi:10.4070/kcj.2019.0107 · Cited by 32

Large animal models of cardiac ischemia-reperfusion injury: Where are we now?

Rahman, A., 香港中文大学医学院内科与药物治疗学系, 香., Li, Y., Chan, T.-K., Zhao, H., Xiang, Y., Chang, X., Zhou, H., Xu, D., Ong, S., et al. (2023) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2022.487 · Cited by 31

Pyroptosis in myocardial ischemia/reperfusion and its therapeutic implications

Liu, Y., Li, X., Sun, T., Li, T., & Li, Q. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176464 · Cited by 31

Inorganic nitrite modulates miRNA signatures in acute myocardial in vivo ischemia/reperfusion

Hendgen-Cotta, U. B., Messiha, D., Esfeld, S., Deenen, R., Rassaf, T., & Totzeck, M. (2017) · Free Radical Research · doi:10.1080/10715762.2017.1282158 · Cited by 31

A growing role for the Hippo signaling pathway in the heart

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Argon Exposure Induces Postconditioning in Myocardial Ischemia–Reperfusion

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