Protein–protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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Items 101–200 of 854

1. Oleanolic, Ursolic, and Betulinic Acids as Food Supplements or Pharmaceutical Agents for Type 2 Diabetes: Promise or Illusion?
   Filomena S. G. Silva, Paulo Jorge Oliveira, Maria F. Duarte · 2016 · Journal of Agricultural and Food Chemistry
2. Insulin resistance induced by tumor necrosis factor-α in myocytes and brown adipocytes12
   M. Lorenzo, Sonia Fernández‐Veledo, Rocío Vila‐Bedmar, Lucía García‐Guerra, Cristina de Álvaro, Iria Nieto-Vázquez · 2007 · Journal of Animal Science
3. Phosphoinositide 3-kinase regulatory subunit p85α suppresses insulin action via positive regulation of PTEN
   Cullen M. Taniguchi, Thien Thuan Tran, Tatsuya Kondo, Ji Luo, Kohjiro Ueki, Lewis C. Cantley, C. Ronald Kahn · 2006 · Proceedings of the National Academy of Sciences
4. Intrauterine Growth Restriction in Humans Is Associated with Abnormalities in Placental Insulin-Like Growth Factor Signaling
   Luigi Laviola, Sebastio Perrini, Gaetana Belsanti, Annalisa Natalicchio, Carmela Montrone, Anna Leonardini, Antonella Vimercati, Marco Scioscia, Luigi Eustacchio Selvaggi, RICCARDO GIORGINO et al. · 2004 · Endocrinology
5. JNK: a new therapeutic target for diabetes
   Brydon L. Bennett · 2003 · Current Opinion in Pharmacology
6. A Phosphatidylinositol 3-Kinase-independent Insulin Signaling Pathway to N-WASP/Arp2/3/F-actin Required for GLUT4 Glucose Transporter Recycling
   Zhen Y. Jiang, Anil Chawla, Avirup Bose, Michael Way, Michael Czech · 2002 · Journal of Biological Chemistry
7. The Q Allele Variant (GLN121) of Membrane Glycoprotein PC-1 Interacts With the Insulin Receptor and Inhibits Insulin Signaling More Effectively Than the Common K Allele Variant (LYS121)
   Benedetta V. Costanzo, Vincenzo Trischitta, Rosa Di Paola, Daniela Spampinato, Antonio Pizzuti, Riccardo Vigneri, Lucia Frittitta · 2001 · Diabetes
8. Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the p85α Regulatory Subunit
   Ueki, Kohjiro, Algenstaedt, Petra, Mauvais-Jarvis, Franck, Kahn, C. Ronald · 2000 · Molecular and Cellular Biology
9. Effects of androgens on insulin action in women: is androgen excess a component of female metabolic syndrome?
   A. Corbould · 2008 · Diabetes/Metabolism Research and Reviews
10. Molecular basis for the insulinomimetic effects of C-peptide
    George Grunberger, Xiaoling Qiang, Zhuojun Li, Suresh T. Mathews, Diego Sbrissa, Assia Shisheva, Anders A. F. Sima · 2001 · Diabetologia
11. Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes
    Ángela M. Valverde, Deborah Jane Burks, Isabel Fabregat, Tracey L. Fisher, José Carretero, Morris F. White, Manuel Benito · 2003 · Diabetes
12. TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
    Francis Kim, Byron M. Gallis, Marshall A. Corson · 2001 · American Journal of Physiology-Cell Physiology
13. The cytohesin Steppke is essential for insulin signalling in Drosophila
    Bernhard Fuß, Thomas Becker, Ingo Zinke, Michael Hoch · 2006 · Nature
14. Withdrawal: Insulin stimulates PKCζ -mediated phosphorylation of insulin receptor substrate-1 (IRS-1): A self-attenuated mechanism to negatively regulate the function of IRS proteins.
    Yanfang Liu, Keren Paz, Avia Herschkovitz, Addy Alt, Tamar Tennenbaum, Sanford R. Sampson, Motoi Ohba, Toshio Kuroki, Derek LeRoith, Yehiel Zick · 2018 · Journal of Biological Chemistry
15. Lipid rafts and insulin signaling
    Perry E. Bickel · 2002 · American Journal of Physiology-Endocrinology and Metabolism
16. Neurohormonal regulation of myocardial cell apoptosis during the development of heart failure
    Koji Hasegawa, Eri Iwai‐Kanai, Shigetake Sasayama · 2000 · Journal of Cellular Physiology
17. Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activator
    Seung Ho Jung, Yun Jung Ha, Eun Kyung Shim, Soo Young Choi, Jingling Jin, Hye Sook Yun‐Choi, Jong Ran Lee · 2007 · Biochemical Journal
18. Effect of Intensive Insulin Therapy on Insulin Sensitivity in the Critically Ill
    Lies Langouche, Sarah Vander Perre, Pieter Jozef Wouters, André J.L. D’Hoore, Troels Krarup Hansen, Greet Van den Berghe · 2007 · The Journal of Clinical Endocrinology & Metabolism
19. A Nucleoprotein Complex Containing Sp1, C/EBPβ, and HMGI-Y Controls Human Insulin Receptor Gene Transcription
    DANIELA PATRIZIA FOTI, Rodolfo Iuliano, EUSEBIO D. CHIEFARI, Antonio Brunetti · 2003 · Molecular and Cellular Biology
20. Melatonin enhances leptin expression by rat adipocytes in the presence of insulin
    Maria Isabel Cardoso Alonso‐Vale, Sandra Andreotti, Sidney Barnabé Peres, Gabriel Forato Anhê, Cristina N. Borges‐Silva, José Cipolla‐Neto, Fábio Bessa Lima · 2004 · American Journal of Physiology-Endocrinology and Metabolism
21. The metabolic abnormalities associated with non-alcoholic fatty liver disease
    Mahmadul Haque, Arun Jayant Sanyal · 2002 · Best Practice & Research Clinical Gastroenterology
22. Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2−/−Mouse Liver
    Kazuyuki Tobe, Ryo Suzuki, Masashi Aoyama, Toshimasa Yamauchi, Junji Kamon, Naoto Kubota, Yasuo Terauchi, Junji Matsui, Yasuo Akanuma, Satoshi Kimura et al. · 2001 · Journal of Biological Chemistry
23. Metabolic and molecular basis of insulin resistance
    Bajaj, Mandeep, DeFronzo, Ralph A · 2003 · Journal of Nuclear Cardiology
24. Lipoatrophic diabetes in Irs1−/−/Irs3−/− double knockout mice
    Palle G. Laustsen, M. Dodson Michael, Barbara E. Crute, Shmuel E. Cohen, Kohjiro Ueki, Rohit N. Kulkarni, Susanna R. Keller, Gustav E. Lienhard, C. Ronald Kahn · 2002 · Genes & Development
25. The metabolic syndrome in overweight epileptic patients treated with valproic acid
    Alberto Verrotti, Rossella Manco, Sergio Agostinelli, Giangennaro Coppola, Francesco Chiarelli · 2009 · Epilepsia
26. Isoproterenol, TNFα, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes
    Susan Kralisch, Johannes Christian Klein, Ulrike Lössner, Matthias Blüher, Ralf Paschke, Michael Stümvoll, Mathias Faßhauer · 2005 · Molecular and Cellular Endocrinology
27. Regulation of Glucose Transport and Insulin Signaling by Troglitazone or Metformin in Adipose Tissue of Type 2 Diabetic Subjects
    Theodore P. Ciaraldi, Alice P.S. Kong, Neelima V. Chu, Dennis Dong Hwan Kim, Sunita C. Baxi, Mattias Loviscach, Raymond A Plodkowski, Richard E. Reitz, Michael P. Caulfield, Sunder Raj D. Mudaliar et al. · 2002 · Diabetes
28. Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia
    Ji Luo, Cassandra L. Sobkiw, Michael F. Hirshman, M. Nicole Logsdon, Timothy Q. Li, Laurie J. Goodyear, Lewis C. Cantley · 2006 · Cell Metabolism
29. Hepatitis C Virus Activates the mTOR/S6K1 Signaling Pathway in Inhibiting IRS-1 Function for Insulin Resistance
    Sandip K. Bose, Shubham Shrivastava, Keith Meyer, Ratna B. Ray, Ranjit Ray · 2012 · Journal of Virology
30. Functions of insulin and insulin receptor signaling in retina: possible implications for diabetic retinopathy
    Chad E.N. Reiter · 2003 · Progress in Retinal and Eye Research
31. Dietary Fiber in the Prevention and Treatment of Metabolic Syndrome: A Review
    Amaya Aleixandre, Marta Miguel · 2008 · Critical Reviews in Food Science and Nutrition
32. Disruption of Sur2 -containing K ATP channels enhances insulin-stimulated glucose uptake in skeletal muscle
    William A. Chutkow, Varman T. Samuel, Polly A. Hansen, Jielin Pu, Carmen R. Valdivia, Jonathan C. Makielski, Charles Burant · 2001 · Proceedings of the National Academy of Sciences
33. Hepatitis C virus infection and insulin resistance
    Bose, Sandip K · 2014 · World J Diabetes
34. Molecular mechanism of insulin resistance
    Samir Bhattacharya, Debleena Dey, Sib Sankar Roy · 2007 · Journal of Biosciences
35. Lack of Insulin Receptor Substrate-2 Causes Progressive Neointima Formation in Response to Vessel Injury
    Tetsuya Kubota, Naoto Kubota, Masao Moroi, Yasuo Terauchi, Tsuneo Kobayashi, Katsuo Kamata, Ryo Suzuki, Kazuyuki Tobe, Atsushi Namiki, Shinichi Aizawa et al. · 2003 · Circulation
36. Dehydroepiandrosterone Stimulates Glucose Uptake in Human and Murine Adipocytes by Inducing GLUT1 and GLUT4 Translocation to the Plasma Membrane
    Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Gaetana Belsanti, Carmela Montrone, Angelo Cignarelli, Vincenza Minielli, Maria Grano, Giovanni De Pergola, RICCARDO GIORGINO et al. · 2004 · Diabetes
37. Impact of Genetic Background on Development of Hyperinsulinemia and Diabetes in Insulin Receptor/Insulin Receptor Substrate-1 Double Heterozygous Mice
    Rohit Kulkarni, Katrine Almind, H. Joseph Goren, Jonathon N. Winnay, Kohjiro Ueki, Terumasa Okada, C. Ronald Kahn · 2003 · Diabetes
38. Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review
    Mariana Di Lorenzo, Nunzia Cacciapuoti, Maria Serena Lonardo, G. Nasti, Claudia Gautiero, Annamaria Belfiore, Bruna Guida, Martina Chiurazzi · 2023 · Current Nutrition Reports
39. Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
    Jiyeon Yang, Yoonjung Park, Hanrui Zhang, Xiangbin Xu, Glen A. Laine, Kevin C. Dellsperger, Cuihua Zhang · 2009 · American Journal of Physiology-Heart and Circulatory Physiology
40. Insulin resistance and obesity
    Jerry Richard Greenfield, Lesley V. Campbell · 2004 · Clinics in Dermatology
41. IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress
    Ruth Potashnik, Asnat Bloch-Damti, Nava Bashan, Assaf Rudich · 2003 · Diabetologia
42. Anti-inflammatory effects of yerba maté extract (Ilex paraguariensis) ameliorate insulin resistance in mice with high fat diet-induced obesity
    Demétrius Paiva Arçari, Waldemar Bartchewsky, Tanila Wood dos Santos, Karim A. Oliveira, Carlorine C. DeOliveira, Érica Martins Ferreira Gotardo, José Pedrazzoli, Alessandra Gambero, Lúcio Fábio Caldas Ferraz, Patrícia de Oliveira Carvalho et al. · 2011 · Molecular and Cellular Endocrinology
43. Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes
    Atsuko Takano, Tetsuro Haruta, Minoru Iwata, Isao Usui, Tatsuhito Uno, Junko Kawahara, Eiichi Ueno, Toshiyasu Sasaoka, Masashi Kobayashi · 2001 · Diabetes
44. Insulin resistance: a phosphorylation-based uncoupling of insulin signaling
    Yehiel Zick · 2001 · Trends in Cell Biology
45. Maternal Overweight Programs Insulin and Adiponectin Signaling in the Offspring
    Kartik Shankar, Ping Kang, Amanda Harrell, Ying Zhong, John C. Marecki, Martin J. J. Ronis, Thomas M. Badger · 2010 · Endocrinology
46. Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways
    Soojeong Kang, Elie R. Chemaly, Roger J. Hajjar, Djamel Lebeche · 2011 · Journal of Biological Chemistry
47. Overnutrition and maternal obesity in sheep pregnancy alter the JNK‐IRS‐1 signaling cascades and cardiac function in the fetal heart
    Jingying Wang, Heng Ma, Chao Tong, Hanying Zhang, Gavin B. Lawlis, Yuanda Li, Mengwei Zang, Jun Tao Ren, Mark J. Nijland, Stephen P. Ford et al. · 2010 · The FASEB Journal
48. Dietary Cod Protein Restores Insulin-Induced Activation of Phosphatidylinositol 3-Kinase/Akt and GLUT4 Translocation to the T-Tubules in Skeletal Muscle of High-Fat-Fed Obese Rats
    Frédéric Tremblay, Charles Lavigne, Hélène Jacques, André Marette · 2003 · Diabetes
49. Anabolic-androgenic steroids induce apoptotic cell death in adult rat ventricular myocytes
    Michael Zaugg, Nasir Z. Jamali, Eliana Lucchinetti, Weimin Xu, Mahmood Alam, Saiyid Ahmad Shafiq, M.A.Q. Siddiqui · 2001 · Journal of Cellular Physiology
50. Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice
    Xizhen Xu, Chun Xia Zhao, Luyun Wang, Ling Tu, Xiaosai Fang, Changlong Zheng, Matthew L. Edin, Darryl C. Zeldin, Dao Wen Wang · 2010 · Diabetes
51. Molecular aspects of diabetes mellitus: Resistin, microRNA, and exosome
    Mohammad Javad Saeedi Borujeni, Ebrahim Esfandiary, Gholamreza Taheripak, Pilar Codoñer‐Franch, Eulalia Alonso‐Iglesias, Hamed Mirzaei · 2017 · Journal of Cellular Biochemistry
52. Surfing the insulin signaling web
    Emmanuel VAN OBBERGHEN, Veronique T. Baron, Laurent Delahaye, Brice Emanuelli, Nathalie Filippa, Sophie Giorgetti‐Peraldi, P. Lebrun, Isabelle Mothe‐Satney, Pascal Peraldi, Stéphane Rocchi et al. · 2001 · European Journal of Clinical Investigation
53. Chronic Ethanol Intake Impairs Insulin Signaling in Rats by Disrupting Akt Association with the Cell Membrane
    Ling He, Frank A. Simmen, Harihara M. Mehendale, Martin J. J. Ronis, Thomas M. Badger · 2006 · Journal of Biological Chemistry
54. In Vivo Phosphorylation of Insulin Receptor Substrate 1 at Serine 789 by a Novel Serine Kinase in Insulin-resistant Rodents
    Qiao, Li-ya, Zhande, Rachel, Jetton, Thomas L., Zhou, Gaochao, Sun, Xiao Jian · 2002 · Journal of Biological Chemistry
55. Sphingomyelin and Its Role in Cellular Signaling
    Mahua Chakraborty, Xian‐Cheng Jiang · 2013 · Advances in experimental medicine and biology
56. PTEN, but Not SHIP2, Suppresses Insulin Signaling through the Phosphatidylinositol 3-Kinase/Akt Pathway in 3T3-L1 Adipocytes
    Xiaoqing Tang, Aimee M. Powelka, Neil A. Soriano, Michael Czech, Adı́lson Guilherme · 2005 · Journal of Biological Chemistry
57. Transcriptional regulation of human insulin receptor gene by the high‐mobility group protein HMGI(Y)
    Antonio Brunetti, Guidalberto Manfioletti, EUSEBIO D. CHIEFARI, Ira D. Goldfine, DANIELA PATRIZIA FOTI · 2001 · The FASEB Journal
58. Impaired PI 3-kinase activation in adipocytes from early growth-restricted male rats
    Susan Elizabeth Ozanne, M. W. Dorling, C. L. Wang, BARBARA T. NAVÉ · 2001 · American Journal of Physiology-Endocrinology and Metabolism
59. Both Src-Dependent and -Independent Mechanisms Mediate Phosphatidylinositol 3-Kinase Regulation of Colony-Stimulating Factor 1-Activated Mitogen-Activated Protein Kinases in Myeloid Progenitors
    Angel W.‐M. Lee, David J. States · 2000 · Molecular and Cellular Biology
60. The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes
    Hagit Eldar-Finkelman, Oksana Kaidanovich‐Beilin · 2002 · Expert Opinion on Therapeutic Targets
61. Insulin Therapy Improves Insulin-Stimulated Endothelial Function in Patients With Type 2 Diabetes and Ischemic Heart Disease
    Christian Rask‐Madsen, Nikolaj Ihlemann, Thure Krarup, Erik Christiansen, Lars Køber, Caroline Nervil Kistorp, Christian Tobias Torp-Pedersen · 2001 · Diabetes
62. The phenotype and functional alterations of macrophages in mice with hyperglycemia for long term
    Chenming Sun, Lina Sun, Haixia Ma, Jianxia Peng, Zhen Yu, Kaizhong Duan, Guangwei Liu, Wenjun Ding, Yong Xiang Zhao · 2011 · Journal of Cellular Physiology
63. Differential Roles of Insulin Receptor Substrates in the Anti-apoptotic Function of Insulin-like Growth Factor-1 and Insulin
    Tseng, Yu-Hua, Ueki, Kohjiro, Kriauciunas, Kristina M., Kahn, C. Ronald · 2002 · Journal of Biological Chemistry
64. Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia
    Rita Kohen Avramoglu, André Theriault, Khosrow Adeli · 2003 · Clinical Biochemistry
65. Direct Administration of Insulin Into Skeletal Muscle Reveals That the Transport of Insulin Across the Capillary Endothelium Limits the Time Course of Insulin to Activate Glucose Disposal
    Jenny D. Chiu, Joyce M. Richey, L. Nicole Harrison, Edward A. Zuniga, Cathryn M. Kolka, Erlinda L. Kirkman, Martin Ellmerer, Richard N. Bergman · 2008 · Diabetes
66. Insulin Signaling in Human Visceral and Subcutaneous Adipose Tissue In Vivo
    Luigi Laviola, Sebastio Perrini, Angelo Cignarelli, Annalisa Natalicchio, Anna Leonardini, Francesca De Stefano, Marilena Cuscito, Michele De Fazio, Vincenzo Memeo, Vincenzo Neri et al. · 2006 · Diabetes
67. Treatment of insulin resistance in diabetes mellitus
    Harold E. Lebovitz, Mary Ann Banerji · 2004 · European Journal of Pharmacology
68. New Insights into the Roles of Insulin/IGF-I in the Development and Maintenance of β-Cell Mass
    Rohit Kulkarni · 2005 · Reviews in Endocrine and Metabolic Disorders
69. Identification of Shc as the Primary Protein Binding to the Tyrosine-phosphorylated β3 Subunit of αIIbβ3 during Outside-in Integrin Platelet Signaling
    Kyra J. Cowan, Debbie A. Law, David R. Phillips · 2000 · Journal of Biological Chemistry
70. Insulin Is a Stronger Inducer of Insulin Resistance than Hyperglycemia in Mice with Type 1 Diabetes Mellitus (T1DM)
    Hui-Yu Liu, Sophia Y. Cao, Tao Hong, Jianmin Han, Zhenqi Liu, Wenhong Cao · 2009 · Journal of Biological Chemistry
71. Isoform-specific insulin receptor signaling involves different plasma membrane domains
    Sabine Uhles, Tilo Moede, Barbara Leibiger, Per‐Olof Berggren, Ingo B. Leibiger · 2003 · The Journal of Cell Biology
72. Glycogen synthase kinase 3β mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1
    San-Hua Leng, Wenshuo Zhang, Yanbin Zheng, Ziva Liberman, Christopher J. Rhodes, Hagit Eldar-Finkelman, Xiao‐Jian Sun · 2010 · Journal of Endocrinology
73. PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
    Manlio Vinciguerra, Michelangelo Foti · 2006 · Archives of Physiology and Biochemistry
74. An ATG Repeat in the 3′-Untranslated Region of the Human Resistin Gene Is Associated with a Decreased Risk of Insulin Resistance
    Antonio Pizzuti, Alessandra Argiolas, Rosa Di Paola, Roberto Baratta, Anna Rauseo, Maura Bozzali, Riccardo Vigneri, Bruno Dallapiccola, Vincenzo Trischitta, Lucia Frittitta · 2002 · The Journal of Clinical Endocrinology & Metabolism
75. Moving the insulin-regulated glucose transporter GLUT4 into and out of storage
    Geoffrey David Holman, Ignacio V. Sandoval · 2001 · Trends in Cell Biology
76. Differential timing for programming of glucose homoeostasis, sensitivity to insulin and blood pressure by in utero exposure to dexamethasone in sheep
    Kathryn L. Gatford, E. Marelyn Wintour, Miles J. De Blasio, Julie A. Owens, Miodrag Dodic · 2000 · Clinical Science
77. Transcriptional and posttranscriptional regulation of the plasminogen activator system
    Robert Lindsay Medcalf, Pura Muñoz‐Cánoves, Yoshikuni Nagamine · 2005 · Thrombosis and Haemostasis
78. Association of SH2-Containing Inositol Phosphatase 2 With the Insulin Resistance of Diabetic db/db Mice
    Hiroyuki Hori, Toshiyasu Sasaoka, Hajime Ishihara, Tsutomu Wada, Shihou Murakami, Manabu Ishiki, Masashi Kobayashi · 2002 · Diabetes
79. Positive and Negative Regulatory Role of Insulin Receptor Substrate 1 and 2 (IRS-1 and IRS-2) Serine/Threonine Phosphorylation
    Michael W. Greene, Robert S. Garofalo · 2002 · Biochemistry
80. Regulation of Receptor Tyrosine Kinase Signaling by GRKs and β-Arrestins
    Christopher J. Hupfeld, Jerrold M. Olefsky · 2006 · Annual Review of Physiology
81. Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease
    Thomas L Platt, Tina L. Beckett, Katharina Köhler, Dana M. Niedowicz, M.P. Murphy · 2015 · Neuroscience
82. Oxysterol Binding Protein Induces Upregulation of SREBP-1c and Enhances Hepatic Lipogenesis
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83. Stimulation of MAPK cascades by insulin and osmotic shock: lack of an involvement of p38 mitogen-activated protein kinase in glucose transport in 3T3-L1 adipocytes.
    Ayse G. Kayali, Darrell A. Austin, Nicholas J. G. Webster · 2000 · Diabetes
84. Insulin can block apoptosis by decreasing oxidative stress via phosphatidylinositol 3-kinase- and extracellular signal-regulated protein kinase-dependent signaling pathways in HepG2 cells
    S Kang, Jinghai Song, Hyunju Kang, S Kim, Youngsook Lee, Daeui Park · 2003 · European Journal of Endocrinology
85. Monitoring the Activation State of the Insulin Receptor Using Bioluminescence Resonance Energy Transfer
    Nicolas Boute, Karine Siquier-Pernet, Tarik Issad · 2001 · Molecular Pharmacology
86. Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance
    Franck Mauvais‐Jarvis, Rohit Kulkarni, C. Ronald Kahn · 2002 · Clinical Endocrinology
87. Coordinate Control of Muscle Cell Survival by Distinct Insulin-like Growth Factor Activated Signaling Pathways
    Margaret A. Lawlor, Peter S. Rotwein · 2000 · The Journal of Cell Biology
88. The Activation Mechanism of the Insulin Receptor: A Structural Perspective
    Eunhee Choi, Xiao‐chen Bai · 2023 · Annual Review of Biochemistry
89. Insulin Signal Transduction in Skeletal Muscle From Glucose-Intolerant Relatives With Type 2 Diabetes
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90. Overlapped Metabolic and Therapeutic Links between Alzheimer and Diabetes
    Waqar Ahmad · 2012 · Molecular Neurobiology
91. Insulin Stimulates Tyrosine Phosphorylation and Inactivation of Protein-tyrosine Phosphatase 1B in Vivo
    Jiangchuan Tao, Craig C. Malbon, Hsien‐yu Wang · 2001 · Journal of Biological Chemistry
92. Acidosis impairs insulin receptor substrate-1-associated phosphoinositide 3-kinase signaling in muscle cells: consequences on proteolysis
    Harold A. Franch, Sina Raissi, Xiaonan Wang, Bin Zheng, James Lynch Bailey, Stephen Russ Price · 2004 · American Journal of Physiology-Renal Physiology
93. Expression of Inducible 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase/PFKFB3 Isoforms in Adipocytes and Their Potential Role in Glycolytic Regulation
    Toshiya Atsumi, Taro Nishio, Hirokatsu Niwa, Jun Takeuchi, Hidenori Bando, Chikara Shimizu, Narihito Yoshioka, Richard Bucala, Takao Koike · 2005 · Diabetes
94. The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle
    Xuxia Wu, Jelai Wang, Xiangqin Cui, Lidia Maianu, Brian K. Rhees, James Rosinski, W. Venus So, Steven Matthew Willi, Michael V. Osier, Helliner S. Hill et al. · 2007 · Endocrine
95. Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect
    Daniel E. Francés, Marı́a Teresa Ronco, Juan Alberto Monti, Paola I. Ingaramo, Gerardo Bruno Pisani, Juan Pablo Parody, José Manuel Pellegrino, Paloma Martín Sanz, Marı́a Cristina Carrillo, Cristina Ester Carnovale · 2010 · Journal of Endocrinology
96. Racial Differences in Insulin Resistance and Mid‐Thigh Fat Deposition in Postmenopausal Women
    Alice S. Ryan, Barbara J. Nicklas, Dora M. Berman · 2002 · Obesity Research
97. Human Insulin Receptor Substrate-1 (IRS-1) Polymorphism G972R Causes IRS-1 to Associate with the Insulin Receptor and Inhibit Receptor Autophosphorylation
    Aileen McGettrick, Edward P. Feener, C. Ronald Kahn · 2004 · Journal of Biological Chemistry
98. Requirement for PIKfyve Enzymatic Activity in Acute and Long-Term Insulin Cellular Effects
    Ognian Christov Ikonomov, Diego Sbrissa, Krzysztof Mlak, Assia Shisheva · 2002 · Endocrinology
99. Insulin Resistance the Link between T2DM and CVD: Basic Mechanisms and Clinical Implications
    Muhammad A Abdul‐Ghani, Amin Jayyousi, Ralph A. DeFronzo, Nidal Asaad, Jassim M. S. Al Suwaidi · 2017 · Current Vascular Pharmacology
100. Role for membrane remodeling in cell death: Implication for health and disease
     Xavier Tekpli, Jørn Andreas Holme, Odile Sergent, Dominique Lagadic‐Gossmann · 2012 · Toxicology